ETS1 associated protein II (TDP2) (NM_016614) Human Untagged Clone
CAT#: SC324645
TDP2 (untagged)-Human tyrosyl-DNA phosphodiesterase 2 (TDP2)
CNY 3,656.00
CNY 7,220.00
Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | AD022; dJ30M3.3; EAP2; EAPII; hTDP2; TTRAP |
Vector | pCMV6-AC |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>OriGene sequence for NM_016614.2
CCCACGCGTCCGGGGGCGGTGCAGAGGCGGCAGGAAGATGGAGTTGGGGAGTTGCCTGGA
GGGCGGGAGGGAGGCGGCGGAGGAAGAGGGCGAGCCTGAGGTGAAAAAGCGGCGACTTCT GTGTGTGGAGTTTGCCTCGGTCGCAAGCTGCGATGCCGCAGTGGCTCAGTGCTTCCTGGC CGAGAACGACTGGGAGATGGAAAGGGCTCTGAACTCCTACTTCGAGCCTCCGGTGGAGGA GAGCGCCTTGGAACGCCGACCTGAAACCATCTCTGAGCCCAAGACCTATGTTGACCTAAC CAATGAAGAAACAACTGATTCCACCACTTCTAAAATCAGCCCATCTGAAGATACTCAGCA AGAAAATGGCAGCATGTTCTCTCTCATTACCTGGAATATTGATGGATTAGATCTAAACAA TCTGTCAGAGAGGGCTCGAGGGGTGTGTTCCTACTTAGCTTTGTACAGCCCAGATGTGAT ATTTCTACAGGAAGTTATTCCCCCATATTATAGCTACCTAAAGAAGAGATCAAGTAATTA TGAGATTATTACAGGTCATGAAGAAGGATATTTCACAGCTATAATGTTGAAGAAATCAAG AGTGAAATTAAAAAGCCAAGAGATTATTCCTTTTCCAAGTACCAAAATGATGAGAAACCT TTTATGTGTGCATGTGAATGTGTCAGGAAATGAGCTTTGCCTTATGACATCCCATTTGGA GAGCACCAGAGGGCATGCTGCGGAACGAATGAATCAGTTAAAAATGGTTTTAAAGAAAAT GCAAGAGGCTCCAGAGTCAGCTACAGTTATATTTGCAGGAGATACAAATCTAAGGGATCG AGAGGTTACCAGATGTGGTGGTTTACCCAACAACATTGTGGATGTCTGGGAGTTTTTGGG CAAACCTAAACATTGCCAGTATACATGGGATACACAAATGAACTCTAATCTTGGAATAAC TGCTGCTTGTAAACTTCGTTTTGATCGAATATTTTTCAGAGCAGCAGCAGAAGAGGGACA CATTATTCCCCGAAGTTTGGACCTTCTTGGATTAGAAAAACTGGACTGTGGTAGATTTCC TAGTGATCACTGGGGTCTTCTGTGCAACTTAGATATAATATTGTAAAATGCTTTTCAAGT GTGGGTTTTGCCCTGATTGTTGCAAATACAATTTCCACCTTCTGGAAAGGTAGGTTTGCT GTGGAGGAAATAATGTACTAGATCATTGTCACAGAAAAACCAACTATGATTTATGGTTGT GTTTTCAGAATTCAACATTAAAGATTAATGTTTATTTAAACGAACACATTCCTGCATTCA GGATGTGAGGCCATTTAATAAAAAGGGCACAAAGCCTGTCAGAGTTTTCAACGGTGCTTA TAGCTGCCAGCTGGATTCCAAACAGGTACCCCATTGTCTCTGAGCTAATGTTTATATTTT TCCATTCAGGCACCGAAATAGTTAATATTTAAAATAAGTCTTCAAAAGAAAACATAAGAG ATTATTGAGTTCTTGGGACTGGATCCTTTATTTCATAAGTTCAGATCATCTTAAATGAAA ATGCCATGATTATCTGCAGTTAAGTAGATGACAGCTATTCTACATCAGACTTGATTTTTG TCAGCTAATTACATAATTGGTAAGCTATAATTGAAACCTTATGGCTTAAAATTCCTTAAC TCCTTTTTGATTCATGTTTGTAGTCATGTTGTCAACAGAGGCAAAGTTAAGCTTGATGAT GGTTAAAATCGGTTTGATAGCACCATGGGACATTTTTCTAACAAAAATAAATGCATGAAG AGACATAGCCTTTTAGTTTTGCTAATTGTGAAATGGAAATGCTTTACAGGAAGTAAATGC AAATTACTTTTAAGTGTGCTTTAAAGAAAAATATTTTCCCCACAAGAGAAATTTAAATAA AGAATTTTATTTGTTTAAAAAAAAAAAAAAAA |
Restriction Sites | Please inquire |
ACCN | NM_016614 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_016614.2, NP_057698.2 |
RefSeq Size | 1940 bp |
RefSeq ORF | 1089 bp |
Locus ID | 51567 |
UniProt ID | O95551 |
Domains | Exo_endo_phos |
Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
Gene Summary | This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
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Specific functions of the Rep and Rep? proteins of porcine circovirus during copy-release and rolling-circle DNA replication
,Cheung, AK;,
Virology
,PubMed ID 25768890
[TDP2]
|
Biochemical Characterization of Human Tyrosyl-DNA Phosphodiesterase 2 (TDP2/TTRAP): A Mg2+/Mn2+-DEPENDENT PHOSPHODIESTERASE SPECIFIC FOR THE REPAIR OF TOPOISOMERASE CLEAVAGE COMPLEXES
,Rui Gao, Shar-yin N. Huang, Christophe Marchand, and Yves Pommier,
J. Biol. Chem., Aug 2012; 287: 30842 - 30852.
[TDP2]
|
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC202015 | TDP2 (Myc-DDK-tagged)-Human tyrosyl-DNA phosphodiesterase 2 (TDP2) |
CNY 3,656.00 |
|
RC202015L1 | Lenti ORF clone of Human tyrosyl-DNA phosphodiesterase 2 (TDP2), Myc-DDK-tagged |
CNY 6,056.00 |
|
RC202015L2 | Lenti ORF clone of Human tyrosyl-DNA phosphodiesterase 2 (TDP2), mGFP tagged |
CNY 5,890.00 |
|
RC202015L3 | Lenti ORF clone of Human tyrosyl-DNA phosphodiesterase 2 (TDP2), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC202015L4 | Lenti ORF clone of Human tyrosyl-DNA phosphodiesterase 2 (TDP2), mGFP tagged |
CNY 5,890.00 |
|
RG202015 | TDP2 (tGFP-tagged) - Human tyrosyl-DNA phosphodiesterase 2 (TDP2) |
CNY 5,256.00 |
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