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Endothelin 3 (EDN3) (NM_207034) Human Untagged Clone
CAT＃: SC324408
EDN3 (untagged)-Human endothelin 3 (EDN3), transcript variant 4
CNY 2,400.00
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ET-3; ET3; HSCR4; PPET3; WS4B |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_207034.1
CGCTGTCCTGGGTGCGCCTCGGGCCGCTGCGCTCCTGGCCAGCTCCCCCCAGCGCCTGGG
AGGCGACCCCCAGTGCGCCCGGGTTCAAAGGCCCGGCGAGGCAGTTCCAGCCCCTCTGGG GGGCGGGGAGGCGACGGGGGTGGTGCAGAAGCCAGAAAAGCCCGAGCCACAGCCGGCCAG CTCCGCGCAGGGATGGGCAGCGCGCTCTGAAAGTTTATGACCGCCGCAGCCAACTCCTGG CCGGAGCTGGAGACGCAGCGAGCGATCGGCCGGCCTCGAACCCCCACAGCTGGAGGGCGA GGCCAGCTGTACCCGGCCCCAGTGCCCTTTCGCGGCCACAAGCGGCCGTCCTCCTGGTCC GGTGCTCCGGCGCCTGATCTAGGTTCATGGAGCCGGGGCTGTGGCTCCTTTTCGGGCTCA CAGTGACCTCCGCCGCAGGATTCGTGCCTTGCTCCCAGTCTGGGGATGCTGGCAGGCGCG GCGTGTCCCAGGCCCCCACTGCAGCCAGATCTGAGGGGGACTGTGAAGAGACTGTGGCTG GCCCTGGCGAGGAGACTGTGGCTGGCCCTGGCGAGGGGACTGTGGCCCCGACAGCACTGC AGGGTCCAAGCCCTGGAAGCCCTGGGCAGGAGCAGGCGGCCGAGGGGGCCCCTGAGCACC ACCGATCCAGGCGCTGCACGTGCTTCACCTACAAGGACAAGGAGTGTGTCTACTATTGCC ACCTGGACATCATTTGGATCAACACTCCCGAACAGACGGTGCCCTATGGACTGTCCAACT ACAGAGGAAGCTTCCGGGGCAAGAGGTCTGCGGGGCCACTTCCAGGGAATCTGCAGCTCT CACATCGGCCACACTTGCGCTGCGCTTGTGTGGGGAGATATGACAAGGCCTGCCTGCACT TTTGCACCCAAACTCTGGACGTCAGCAGTAATTCAAGGACGGCAGAAAAAACAGACAAAG AAGAGGAAGGGAAGGTTGAAGTCAAGGACCAACAAAGCAAGCAGGCTTTAGACCTCCACC ATCCAAAGCTCATGCCCGGCAGTGGACTCGCCCTCGCTCCATCTACCTGCCCCCGCTGCC TCTTTCAGGAAGGAGCCCCTTAGGAGGACAGGCCTGCAGCATCCTGGTCTCGGGAGGCTT CTGTCATTGCTCACACACAGTTCAGATTTCCACCTCTTTATAGACAAGAAGTGAATTTGC CTGGGGCAGAACACCCACCCAAAGAGTCCCCACTTAACAATACCCCCCCCCCACGGCAAG AATGCCCAAATCCGAATGACCCCAGTTTTCCTAATGAGTAAAATGATCCCAGATGTGCCC CAGAGCATGACGCCTGCAGCTCCGGTTTCATGCAGGAAATTGGTTTTGGAGAGTTTTGGC AAGTTGGAAAGCCACTTACTGGCTTTTGACATGACTTCTCTTGGAGAATAAGTGGACTCC AAGCTAACTCTTTGCAAATGTAAACACATGTCCATCTTGTAATAAATGCAAAATGCCCGT GCAGCAGAAGCATGCGACTTTCATATCCTTGCCTAGAATAGGCTGCATGGTGTATGTCAG TGAGGGCCACGAGGCGTCGGCTTTAGACACAGATCATAGCTCTACAGGAGTTTATGAATT TGAAGCTTATGGGATTTTGGCAGAGAAATTTTCAGCTGTGCTTGATACCCACCAAAAGAA TGTATCTCGAAAGAATGAAGGAAGAAGAAAAAAGGATCCTTGATGTTTGTGACAAGAAAA TGAGAAAGTTAGTATCTGCAATACAGAGCTTGTTCCTGTTCAGTGACTGACCCTCTGTAT TCTGTATAGACACCAGGCCGATACACAGTGGAGTTCCCAGGCCTTGTTTGCAGGAAGCCG ACTGTAAAGACAGCCCCAGCTCAAGGCTATTAGGTTGAATATTTGCTTTCATGAGTAAAT GTGGATCTTTGGGGAATGGCTTCAAAATAAGTCACGAACACAAATTCTTTGTAAATTATG TAAATTCCTGTTTATATAAATTGGCAACAACTTATACCGTCTGACAGTTCAAAATCTCTT TCAGCTGCGCTCTTCCCACCGAGCCGAGCTTACTGTGAGTGTGGAGATGTTATCCCACCA TGTAAAGTCGCCTGCGCAGGGGAGGGCTGCCCATCTCCCCAACCCAGTCACAGAGAGATA GGAAACGGCATTTGAGTGGGTGTCCAGGGCCCCGTAGAGAGACATTTAAGATGGTGTATG ACAGAGCATTGGCCTTGACCAAATGTTAAATCCTCTGTGTGTATTTCATAAGTTATTACA GGTATAAAAGTGATGACCTATCATGAGGAAATGAAAGTGGCTGATTTGCTGGTAGGATTT TGTACAGTTTAGAGAAGCGATTATTTATTGTGAAACTGTTCTCCACTCCAACTCCTTTAT GTGGATCTGTTCAAAGTAGTCACTGTATATACGTATAGAGAGGTAGATAGGTAGGTAGAT TTTAAATTGCATTCTGAATACAAACTCATACTCCTTAGAGCTTGAATTACATTTTTAAAA TGCATATGTGCTGTTTGGCACCGTGGCAAGATGGTATCAGAGAGAAACCCATCAATTGCT CAAATACTCAGAAAGTACTGTCAAAAGCCTAATAAAAAACCTAAAGTTTGCTCTGAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_207034 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_207034.1, NP_996917.1 |
| RefSeq Size | 2659 bp |
| RefSeq ORF | 717 bp |
| Locus ID | 1908 |
| UniProt ID | P14138 |
| Protein Families | Druggable Genome, Secreted Protein |
| Gene Summary | The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014] Transcript Variant: This variant (4) encodes the longest isoform (1). |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203410 | EDN3 (Myc-DDK-tagged)-Human endothelin 3 (EDN3), transcript variant 4 |
CNY 2,400.00 |
|
| RC203410L3 | Lenti ORF clone of Human endothelin 3 (EDN3), transcript variant 4, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203410L4 | Lenti ORF clone of Human endothelin 3 (EDN3), transcript variant 4, mGFP tagged |
CNY 5,890.00 |
|
| RG203410 | EDN3 (tGFP-tagged) - Human endothelin 3 (EDN3), transcript variant 4 |
CNY 4,000.00 |
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