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Thimet Oligopeptidase (THOP1) (NM_003249) Human Untagged Clone
CAT＃: SC324358
THOP1 (untagged)-Human thimet oligopeptidase 1 (THOP1)
CNY 5,056.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EP24.15; MEPD_HUMAN; MP78; TOP |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_003249.3
GCCCCGGGAGCGCGGGCGGCGGGCCCCTTGGTCCTCAGGCGGCCGTGGCGGCGGTGGCGG
CGGTTGGGCCGAGGCAGGCGGCCTCAGTGGCCGAGGTGGCTGGACGCGTAGCAGGTGGAA GGAGGGAGGGAGCCGCAGGCGCAGACCCACCCGCCATGAAGCCCCCCGCAGCCTGTGCAG GAGACATGGCGGACGCAGCATCTCCGTGCTCTGTGGTAAACGACCTGCGGTGGGACCTGA GTGCCCAGCAGATAGAGGAGCGCACCAGGGAGCTCATCGAGCAGACCAAGCGCGTGTATG ACCAGGTTGGCACCCAGGAGTTTGAGGACGTGTCCTACGAGAGCACGCTCAAGGCGCTGG CCGATGTGGAGGTCACCTACACAGTTCAGAGGAATATCCTTGACTTCCCCCAGCATGTTT CCCCCTCCAAGGACATCCGGACAGCCAGCACAGAGGCCGACAAGAAGCTCTCTGAGTTCG ACGTGGAGATGAGCATGAGGGAGGACGTGTACCAGAGGATCGTGTGGCTCCAGGAGAAAG TTCAGAAGGACTCACTGAGGCCCGAGGCTGCGCGGTACCTGGAGCGGCTAATCAAGCTGG GCCGGAGAAATGGGCTTCACCTCCCCAGAGAGACTCAGGAAAACATCAAACGCATCAAGA AGAAGCTGAGCCTTCTGTGCATCGACTTCAACAAGAACCTGAACGAGGACACGACCTTCC TGCCCTTCACGCTCCAGGAGCTAGGAGGGCTCCCCGAGGACTTTCTGAACTCCCTGGAGA AGATGGAGGACGGCAAGTTGAAGGTCACCCTCAAGTACCCCCATTACTTCCCCCTCCTGA AGAAATGCCACGTGCCTGAGACCAGGAGGAAAGTGGAGGAGGCCTTCAACTGCCGGTGCA AGGAGGAGAACTGCGCTATCCTCAAGGAGCTGGTGACGCTGCGGGCCCAGAAGTCCCGCC TGCTGGGGTTCCACACGCACGCCGACTATGTCCTGGAGATGAACATGGCCAAGACCAGCC AGACCGTGGCCACCTTCCTAGATGAGCTGGCGCAGAAGCTGAAGCCCCTGGGGGAGCAGG AGCGTGCGGTGATTCTGGAGCTGAAGCGTGCGGAGTGCGAGCGCCGGGGCCTGCCCTTCG ACGGCCGCATCCGTGCCTGGGACATGCGCTACTACATGAACCAGGTGGAGGAGACGCGCT ACTGCGTGGACCAGAACCTGCTCAAGGAGTACTTCCCCGTGCAGGTGGTCACGCACGGGC TGCTGGGCATCTACCAGGAGCTCCTGGGGCTGGCCTTCCACCACGAGGAGGGCGCCAGTG CCTGGCATGAGGACGTGCGGCTCTACACCGCGAGGGACGCGGCCTCGGGGGAGGTGGTCG GCAAGTTCTACCTGGACCTGTACCCGCGGGAAGGAAAGTACGGGCACGCGGCCTGCTTTG GCCTGCAGCCCGGCTGCCTGCGGCAGGATGGGAGCCGCCAGATCGCCATCGCGGCCATGG TGGCCAACTTCACCAAGCCCACAGCCGACGCGCCCTCGCTGCTGCAGCATGACGAGGTGG AGACCTACTTCCATGAGTTTGGCCACGTGATGCACCAGCTCTGCTCCCAGGCGGAGTTCG CCATGTTCAGCGGGACCCACGTGGAGCGGGACTTTGTGGAGGCGCCGTCGCAGATGCTGG AGAACTGGGTGTGGGAGCAGGAGCCGCTGCTGCGGATGTCGCGGCACTACCGCACAGGCA GCGCCGTGCCCCGGGAGCTCCTGGAGAAGCTCATTGAGTCCCGGCAGGCCAACACAGGCC TCTTCAACCTGCGCCAGATCGTCCTCGCCAAGGTGGACCAGGCCCTGCACACGCAGACGG ACGCAGACCCCGCCGAGGAGTATGCGCGGCTCTGCCAGGAGATCCTCGGGGTCCCGGCCA CGCCAGGAACCAACATGCCTGCAACCTTCGGCCATCTGGCAGGTGGCTACGACGCCCAGT ACTACGGGTACCTGTGGAGCGAGGTGTATTCCATGGACATGTTCCACACGCGCTTCAAGC AGGAGGGTGTCCTGAACAGCAAGGTTGGCATGGATTACAGAAGCTGCATCCTGAGACCCG GCGGTTCCGAGGATGCCAGCGCCATGCTGAGGCGCTTCCTGGGCCGTGACCCCAAGCAGG ACGCCTTCCTCCTGAGCAAGGGGCTGCAGGTCGGGGGCTGCGAGCCCGAGCCGCAGGTCT GCTGAGGCCTGGCACTGCGACTGCCCAGTCTGGCCTGCGCTCCCGCCGCCCTGGTGCCTT AGCCCCCGGCACAGGATGGGGCAGGCTCTGGCACAGTGCCTGGGACTGGCAGGGTGGCTG AGCGGCTGTCTTGCCTCTTGTCATTGTCTGTCCCCACCCGGTCGTGGCCCACCCGGCTAG AGACGGCGTCCTCAAGGCATCTGGAGGGCTTTCGTGGCTGCCAGGGCCTGGTCTTTGTTG CACTAACACGTCTCCTCTCTGGGAAACGTCCCTTGTCAGGAGACGGCTCTTCTTTGAAAT GAGGTCATTAAAAGGAAACAGAAAAAGAGAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_003249 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003249.3, NP_003240.1 |
| RefSeq Size | 2568 bp |
| RefSeq ORF | 2070 bp |
| Locus ID | 7064 |
| UniProt ID | P52888 |
| Domains | Peptidase_M3 |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Renin-angiotensin system |
| Gene Summary | The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. [provided by RefSeq, Nov 2015] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201738 | THOP1 (Myc-DDK-tagged)-Human thimet oligopeptidase 1 (THOP1) |
CNY 5,048.00 |
|
| RC201738L3 | Lenti ORF clone of Human thimet oligopeptidase 1 (THOP1), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC201738L4 | Lenti ORF clone of Human thimet oligopeptidase 1 (THOP1), mGFP tagged |
CNY 7,448.00 |
|
| RG201738 | THOP1 (tGFP-tagged) - Human thimet oligopeptidase 1 (THOP1) |
CNY 6,648.00 |
|
| SC118078 | THOP1 (untagged)-Human thimet oligopeptidase 1 (THOP1) |
CNY 5,056.00 |
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