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Beclin 1 (BECN1) (NM_003766) Human Untagged Clone
CAT＃: SC324265
BECN1 (untagged)-Human beclin 1, autophagy related (BECN1)
CNY 5,488.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ATG6; beclin1; VPS30 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_003766.2
GCTGAAGACAGAGCGATGGTAGTTCTGGAGGCCTCGCTCCGGGGCCGACCCGAGGCCACA
GTGCCTCCGCGGTAGACCGGACTTGGGTGACGGGCTCCGGGCTCCCGAGGTGAAGAGCAT CGGGGGCTGAGGGATGGAAGGGTCTAAGACGTCCAACAACAGCACCATGCAGGTGAGCTT CGTGTGCCAGCGCTGCAGCCAGCCCCTGAAACTGGACACGAGTTTCAAGATCCTGGACCG TGTCACCATCCAGGAACTCACAGCTCCATTACTTACCACAGCCCAGGCGAAACCAGGAGA GACCCAGGAGGAAGAGACTAACTCAGGAGAGGAGCCATTTATTGAAACTCCTCGCCAGGA TGGTGTCTCTCGCAGATTCATCCCCCCAGCCAGGATGATGTCCACAGAAAGTGCCAACAG CTTCACTCTGATTGGGGAGGCATCTGATGGCGGCACCATGGAGAACCTCAGCCGAAGACT GAAGGTCACTGGGGACCTTTTTGACATCATGTCGGGCCAGACAGATGTGGATCACCCACT CTGTGAGGAATGCACAGATACTCTTTTAGACCAGCTGGACACTCAGCTCAACGTCACTGA AAATGAGTGTCAGAACTACAAACGCTGTTTGGAGATCTTAGAGCAAATGAATGAGGATGA CAGTGAACAGTTACAGATGGAGCTAAAGGAGCTGGCACTAGAGGAGGAGAGGCTGATCCA GGAGCTGGAAGACGTGGAAAAGAACCGCAAGATAGTGGCAGAAAATCTCGAGAAGGTCCA GGCTGAGGCTGAGAGACTGGATCAGGAGGAAGCTCAGTATCAGAGAGAATACAGTGAATT TAAACGACAGCAGCTGGAGCTGGATGATGAGCTGAAGAGTGTTGAAAACCAGATGCGTTA TGCCCAGACGCAGCTGGATAAGCTGAAGAAAACCAACGTCTTTAATGCAACCTTCCACAT CTGGCACAGTGGACAGTTTGGCACAATCAATAACTTCAGGCTGGGTCGCCTGCCCAGTGT TCCCGTGGAATGGAATGAGATTAATGCTGCTTGGGGCCAGACTGTGTTGCTGCTCCATGC TCTGGCCAATAAGATGGGTCTGAAATTTCAGAGATACCGACTTGTTCCTTACGGAAACCA TTCATATCTGGAGTCTCTGACAGACAAATCTAAGGAGCTGCCGTTATACTGTTCTGGGGG GTTGCGGTTTTTCTGGGACAACAAGTTTGACCATGCAATGGTGGCTTTCCTGGACTGTGT GCAGCAGTTCAAAGAAGAGGTTGAGAAAGGCGAGACACGTTTTTGTCTTCCCTACAGGAT GGATGTGGAGAAAGGCAAGATTGAAGACACAGGAGGCAGTGGCGGCTCCTATTCCATCAA AACCCAGTTTAACTCTGAGGAGCAGTGGACAAAAGCTCTCAAGTTCATGCTGACGAATCT TAAGTGGGGTCTTGCTTGGGTGTCCTCACAATTTTATAACAAATGACTTTTTTCCTTAGG GGGAGGTTTGCCTTAAAGGCTTTTAATTTTGTTTTGTTTGCAAACATGTTTTAAATTAAA TTCGGGTAATATTAAACAGTACATGTTTACAATACCAAAAAAGAAAAAATCCACAAAAGC CACTTTATTTTAAAATATCATGTGACAGATACTTTCCAGAGCTACAACATGCCATCTATA GTTGCCAGCCCTGGTCAGTTTTGATTCTTAACCCCATGGACTCCTTTCCCTTTCTTCTCT GAAAAAAACTAATTTAAATTTGCTTTTCTTTTTTTTAACTGAGTTGAATTGAGATTGATG TGTTTTCACTGGATTTTTATCTCTCTCAACTTCCTGCACTTAACAATATGAAATAGAAAC TTTTGTCTTTACTGAGATGAGGATATGTTTGAGATGCACAGTTGGATAATGTGGGAAAAT GACATCTAAGCTTTACCTGGTCACCATGTGATGTGATCAGATGCTTGAAATTTAACACTT TTCACTTGGTTCTTATACTGAATGCCGACTCTGCTCTGTGTTAGAGATATGAAATGGTGT TTGATACTGTTTGAGACATTATGGAGAGATTTAATTATTTGTAATAAAAGATTTGCTGCA GTCTGAAAACTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_003766 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003766.2, NP_003757.1 |
| RefSeq Size | 2144 bp |
| RefSeq ORF | 1353 bp |
| Locus ID | 8678 |
| UniProt ID | Q14457 |
| Domains | APG6 |
| Protein Families | Druggable Genome |
| Protein Pathways | Regulation of autophagy |
| Gene Summary | This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1 and 2 encode the same isoform. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201629 | BECN1 (Myc-DDK-tagged)-Human beclin 1, autophagy related (BECN1) |
CNY 5,488.00 |
|
| RC201629L1 | Lenti ORF clone of Human beclin 1, autophagy related (BECN1), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC201629L2 | Lenti ORF clone of Human beclin 1, autophagy related (BECN1), mGFP tagged |
CNY 7,888.00 |
|
| RC201629L3 | Lenti ORF clone of Human beclin 1, autophagy related (BECN1), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC201629L4 | Lenti ORF clone of Human beclin 1, autophagy related (BECN1), mGFP tagged |
CNY 7,888.00 |
|
| RG201629 | BECN1 (tGFP-tagged) - Human beclin 1, autophagy related (BECN1) |
CNY 7,088.00 |
|
| SC117750 | BECN1 (untagged)-Human beclin 1, autophagy related (BECN1) |
CNY 2,950.00 |
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