Beclin 1 (BECN1) (NM_003766) Human Untagged Clone

CAT#: SC324265

BECN1 (untagged)-Human beclin 1, autophagy related (BECN1)



  "NM_003766" in other vectors (7)

CNY 5,488.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
BECN1 (Beclin 1) mouse monoclonal antibody, clone OTI1F1 (formerly 1F1)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms ATG6; beclin1; VPS30
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_003766.2 GCTGAAGACAGAGCGATGGTAGTTCTGGAGGCCTCGCTCCGGGGCCGACCCGAGGCCACA
GTGCCTCCGCGGTAGACCGGACTTGGGTGACGGGCTCCGGGCTCCCGAGGTGAAGAGCAT
CGGGGGCTGAGGGATGGAAGGGTCTAAGACGTCCAACAACAGCACCATGCAGGTGAGCTT
CGTGTGCCAGCGCTGCAGCCAGCCCCTGAAACTGGACACGAGTTTCAAGATCCTGGACCG
TGTCACCATCCAGGAACTCACAGCTCCATTACTTACCACAGCCCAGGCGAAACCAGGAGA
GACCCAGGAGGAAGAGACTAACTCAGGAGAGGAGCCATTTATTGAAACTCCTCGCCAGGA
TGGTGTCTCTCGCAGATTCATCCCCCCAGCCAGGATGATGTCCACAGAAAGTGCCAACAG
CTTCACTCTGATTGGGGAGGCATCTGATGGCGGCACCATGGAGAACCTCAGCCGAAGACT
GAAGGTCACTGGGGACCTTTTTGACATCATGTCGGGCCAGACAGATGTGGATCACCCACT
CTGTGAGGAATGCACAGATACTCTTTTAGACCAGCTGGACACTCAGCTCAACGTCACTGA
AAATGAGTGTCAGAACTACAAACGCTGTTTGGAGATCTTAGAGCAAATGAATGAGGATGA
CAGTGAACAGTTACAGATGGAGCTAAAGGAGCTGGCACTAGAGGAGGAGAGGCTGATCCA
GGAGCTGGAAGACGTGGAAAAGAACCGCAAGATAGTGGCAGAAAATCTCGAGAAGGTCCA
GGCTGAGGCTGAGAGACTGGATCAGGAGGAAGCTCAGTATCAGAGAGAATACAGTGAATT
TAAACGACAGCAGCTGGAGCTGGATGATGAGCTGAAGAGTGTTGAAAACCAGATGCGTTA
TGCCCAGACGCAGCTGGATAAGCTGAAGAAAACCAACGTCTTTAATGCAACCTTCCACAT
CTGGCACAGTGGACAGTTTGGCACAATCAATAACTTCAGGCTGGGTCGCCTGCCCAGTGT
TCCCGTGGAATGGAATGAGATTAATGCTGCTTGGGGCCAGACTGTGTTGCTGCTCCATGC
TCTGGCCAATAAGATGGGTCTGAAATTTCAGAGATACCGACTTGTTCCTTACGGAAACCA
TTCATATCTGGAGTCTCTGACAGACAAATCTAAGGAGCTGCCGTTATACTGTTCTGGGGG
GTTGCGGTTTTTCTGGGACAACAAGTTTGACCATGCAATGGTGGCTTTCCTGGACTGTGT
GCAGCAGTTCAAAGAAGAGGTTGAGAAAGGCGAGACACGTTTTTGTCTTCCCTACAGGAT
GGATGTGGAGAAAGGCAAGATTGAAGACACAGGAGGCAGTGGCGGCTCCTATTCCATCAA
AACCCAGTTTAACTCTGAGGAGCAGTGGACAAAAGCTCTCAAGTTCATGCTGACGAATCT
TAAGTGGGGTCTTGCTTGGGTGTCCTCACAATTTTATAACAAATGACTTTTTTCCTTAGG
GGGAGGTTTGCCTTAAAGGCTTTTAATTTTGTTTTGTTTGCAAACATGTTTTAAATTAAA
TTCGGGTAATATTAAACAGTACATGTTTACAATACCAAAAAAGAAAAAATCCACAAAAGC
CACTTTATTTTAAAATATCATGTGACAGATACTTTCCAGAGCTACAACATGCCATCTATA
GTTGCCAGCCCTGGTCAGTTTTGATTCTTAACCCCATGGACTCCTTTCCCTTTCTTCTCT
GAAAAAAACTAATTTAAATTTGCTTTTCTTTTTTTTAACTGAGTTGAATTGAGATTGATG
TGTTTTCACTGGATTTTTATCTCTCTCAACTTCCTGCACTTAACAATATGAAATAGAAAC
TTTTGTCTTTACTGAGATGAGGATATGTTTGAGATGCACAGTTGGATAATGTGGGAAAAT
GACATCTAAGCTTTACCTGGTCACCATGTGATGTGATCAGATGCTTGAAATTTAACACTT
TTCACTTGGTTCTTATACTGAATGCCGACTCTGCTCTGTGTTAGAGATATGAAATGGTGT
TTGATACTGTTTGAGACATTATGGAGAGATTTAATTATTTGTAATAAAAGATTTGCTGCA
GTCTGAAAACTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_003766
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_003766.2, NP_003757.1
RefSeq Size 2144 bp
RefSeq ORF 1353 bp
Locus ID 8678
UniProt ID Q14457
Domains APG6
Protein Families Druggable Genome
Protein Pathways Regulation of autophagy
Gene Summary This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1 and 2 encode the same isoform.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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