IL15 (NM_000585) Human Untagged Clone

CAT#: SC324164

IL15 (untagged)-Human interleukin 15 (IL15), transcript variant 3



  "NM_000585" in other vectors (4)

CNY 1,200.00

CNY 3,990.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
IL15 mouse monoclonal antibody, clone OTI2B4 (formerly 2B4)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms IL-15
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_000585.2 ACTCCGGGTGGCAGGCGCCCGGGGGAATCCCAGCTGACTCGCTCACTGCCTTCGAAGTCC
GGCGCCCCCCGGGAGGGAACTGGGTGGCCGCACCCTCCCGGCTGCGGTGGCTGTCGCCCC
CCACCCTGCAGCCAGGACTCGATGGAGGTACAGAGCTCGGCTTCTTTGCCTTGGGAGGGG
AGTGGTGGTGGTTGAAAGGGCGATGGAATTTTCCCCGAAAGCCTACGCCCAGGGCCCCTC
CCAGCTCCAGCGTTACCCTCCGGTCTATCCTACTGGCCGAGCTGCCCCGCCTTCTCATGG
GGAAAACTTAGCCGCAACTTCAATTTTTGGTTTTTCCTTTAATGACACTTCTGAGGCTCT
CCTAGCCATCCTCCCGCTTCCGGAGGAGCGCAGATCGCAGGTCCCTTTGCCCCTGGCGTG
CGACTCCCTACTGCGCTGCGCTCTTACGGCGTTCCAGGCTGCTGGCTAGCGCAAGGCGGG
CCGGGCACCCCGCGCTCCGCTGGGAGGGTGAGGGACGCGCGTCTGGCGGCCCCAGCCAAG
CTGCGGGTTTCTGAGAAGACGCTGTCCCGCAGCCCTGAGGGCTGAGTTCTGCACCCAGTC
AAGCTCAGGAAGGCCAAGAAAAGAATCCATTCCAATATATGGCCATGTGGCTCTTTGGAG
CAATGTTCCATCATGTTCCATGCTGCTGACGTCACATGGAGCACAGAAATCAATGTTAGC
AGATAGCCAGCCCATACAAGATCGTATTGTATTGTAGGAGGCATCGTGGATGGATGGCTG
CTGGAAACCCCTTGCCATAGCCAGCTCTTCTTCAATACTTAAGGATTTACCGTGGCTTTG
AGTAATGAGAATTTCGAAACCACATTTGAGAAGTATTTCCATCCAGTGCTACTTGTGTTT
ACTTCTAAACAGTCATTTTCTAACTGAAGCTGGCATTCATGTCTTCATTTTGGGCTGTTT
CAGTGCAGGGCTTCCTAAAACAGAAGCCAACTGGGTGAATGTAATAAGTGATTTGAAAAA
AATTGAAGATCTTATTCAATCTATGCATATTGATGCTACTTTATATACGGAAAGTGATGT
TCACCCCAGTTGCAAAGTAACAGCAATGAAGTGCTTTCTCTTGGAGTTACAAGTTATTTC
ACTTGAGTCCGGAGATGCAAGTATTCATGATACAGTAGAAAATCTGATCATCCTAGCAAA
CAACAGTTTGTCTTCTAATGGGAATGTAACAGAATCTGGATGCAAAGAATGTGAGGAACT
GGAGGAAAAAAATATTAAAGAATTTTTGCAGAGTTTTGTACATATTGTCCAAATGTTCAT
CAACACTTCTTGATTGCAATTGATTCTTTTTAAAGTGTTTCTGTTATTAACAAACATCAC
TCTGCTGCTTAGACATAACAAAACACTCGGCATTTCAAATGTGCTGTCAAAACAAGTTTT
TCTGTCAAGAAGATGATCAGACCTTGGATCAGATGAACTCTTAGAAATGAAGGCAGAAAA
ATGTCATTGAGTAATATAGTGACTATGAACTTCTCTCAGACTTACTTTACTCATTTTTTT
AATTTATTATTGAAATTGTACATATTTGTGGAATAATGTAAAATGTTGAATAAAAATATG
TACAAGTGTTGTTTTTTAAGTTGCACTGATATTTTACCTCTTATTGCAAAATAGCATTTG
TTTAAGGGTGATAGTCAAATTATGTATTGGTGGGGCTGGGTACCAATGCTGCAGGTCAAC
AGCTATGCTGGTAGGCTCCTGCCTGTGTGGAACCACTGACTACTGGCTCTCATTGACTTC
CTTACTAAGCATAGCAAACAGAGGAAGAATTTGTTATCAGTAAGAAAAAGAAGAACTATA
TGTGAATCCTCTTCTTTACACTGTAATTTAGTTATTGATGTATAAAGCAACTGTTATGAA
ATAAAGAAATTGCAATAACTGGCAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites ECoRI-NOT     
ACCN NM_000585
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_000585.2, NP_000576.1
RefSeq Size 1496 bp
RefSeq ORF 489 bp
Locus ID 3600
UniProt ID P40933
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
Gene Summary The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011]
Transcript Variant: This variant (3) represents the shortest transcript and encodes the longer isoform (1, also known as 48aa(LSP)-IL15).
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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