PPM1B (NM_177969) Human Untagged Clone

CAT#: SC324040

PPM1B (untagged)-Human protein phosphatase, Mg2+/Mn2+ dependent, 1B (PPM1B), transcript variant 3



  "NM_177969" in other vectors (5)

CNY 2,400.00

CNY 3,990.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
PPM1B mouse monoclonal antibody, clone OTI3C9 (formerly 3C9)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms PP2C-beta; PP2C-beta-X; PP2CB; PP2CBETA; PPC2BETAX
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_177969.2 TGCTCAATGGCGGAAAAGCCGCCGGTGCTCTGACGGCCTCGTTCCCCTAGCAGTTGCGGG
GGAGTTTCCTGCCGGCGCGGCTGGAGTCTCTGATTCTCAGGGTTCGGTGGTTGGAAGATG
CTCCAGAGAGACGAGGCTGCGGCGGAGGAGGTGGCGGCGGCCGAATCGGCAACGGCGCTA
GGGTGGAGAGAAGGCGGCAGCGGCGGCGGCGGCGGCGTGAGGGGCCGGGCGGTGTAAACA
GCCCCGGAGGCGGCGGAGGCGGCGGTCGAGACCCCGAGGGGGAAGCGGCGGCTGAGTCAG
GGTCGCGCCTCCGTTGGAAACTTGGGCTGAGTACCGCGGCGGGCGCGAGCGAGGCGCCCT
AGACATCTTCTCCCTCCCTTGCCTCAGATTTATTGCTAAACATGGGTGCATTTTTGGATA
AACCCAAAACTGAAAAACATAATGCTCATGGTGCTGGGAATGGTTTACGTTATGGCCTGA
GCAGCATGCAAGGATGGAGAGTGGAAATGGAAGATGCACACACAGCTGTTGTAGGTATTC
CTCACGGCTTGGAAGACTGGTCATTTTTTGCAGTTTATGATGGTCATGCTGGATCCCGAG
TGGCAAATTACTGCTCAACACATTTATTAGAACACATCACTACTAACGAAGACTTTAGGG
CAGCTGGAAAATCAGGATCTGCTCTTGAGCTTTCAGTGGAAAATGTTAAGAATGGTATCA
GAACTGGATTTTTGAAAATTGATGAATACATGCGTAACTTTTCAGACCTCAGAAACGGGA
TGGACAGGAGTGGTTCAACTGCAGTGGGAGTTATGATTTCACCTAAGCATATCTACTTTA
TCAACTGTGGTGATTCACGTGCTGTTCTGTATAGGAATGGACAAGTCTGCTTTTCTACCC
AGGATCACAAACCTTGCAATCCAAGGGAAAAGGAGCGAATCCAAAATGCAGGAGGCAGCG
TGATGATACAACGTGTTAATGGTTCATTAGCAGTATCTCGTGCTCTGGGGGACTATGATT
ACAAGTGTGTTGATGGCAAGGGCCCAACAGAACAACTTGTTTCTCCAGAGCCTGAGGTTT
ATGAAATTTTAAGAGCAGAAGAGGATGAATTTATCATCTTGGCTTGTGATGGGATCTGGG
ATGTTATGAGTAATGAGGAGCTCTGTGAATATGTTAAATCTAGGCTTGAGGTATCTGATG
ACCTGGAAAATGTGTGCAATTGGGTAGTGGACACTTGTTTACACAAGGGAAGTCGAGATA
ACATGAGTATTGTACTAGTTTGCTTTTCAAATGCTCCCAAGGTCTCAGATGAAGCGGTGA
AAAAAGATTCAGAGTTGGATAAGCACTTGGAATCACGGGTTGAAGAGATTATGGAGAAGT
CTGGCGAGGAAGGAATGCCTGATCTTGCCCATGTCATGCGCATCTTGTCTGCAGAAAATA
TCCCAAATTTGCCTCCTGGGGGAGGTCTTGCTGGCAAGCGTAATGTTATTGAAGCTGTTT
ATAGTAGACTGAATCCACATAGAGAAAGTGATGGGGCCTCCGATGAAGCAGAGGAAAGTG
GATCACAGGGAAAATTGGTGGAAGCTCTCAGGCAAATGAGAATTAATCATAGGGGAAACT
ACCGACAACTTCTGGAGGAGATGCTGACTAGTTACAGGCTAGCTAAAGTAGAGGGAGAAG
AAAGCCCTGCTGAACCAGCTGCCACAGCTACTTCTTCGAACAGTGATGCTGGAAACCCAG
TGACAATGCAGGAAAGCCATACTGAATCAGAAAGTGGTCTTGCTGAATTAGACAGCTCTA
ATGAAGATGCAGGGACAAAGATGAGTGGTGAAAAAATATGACTTTCCTTTTTGGTAATAT
TTTTGTGATCTTTGATGGTTTTTAACCTAGGAAGTGTAATGTATGCATTTATATAACTGT
TTTGTTATTTGAATCTTGGAAAACTAGTTTTATTATATTCAGATAGCCTTGTTTTTTAAA
AAGGCCTTTGCATACACCTTTATGAGATAGTGTAAAATTGACTATTTATAGTACTATGGA
TTTAATGAAATTATATGTCATTTCACATTGTATGCCAGAAATTAGGCTACCAATTATGAA
TTAAAGTCAGTAGTTAAATTAATACTAGATAGAATTAGAAATTTTGATTAGAGAGATTAT
GCTATATTATGGAAAAACTTGTTAATGTAGAATTATACTGCTTCATATTATTTTACCTAT
TAGTACACTCATAGTTAGCTTTGTAATAAATTTATGTTTTCTTTAATAATTTTAGTTCTT
CAAAGAATGGCTGATGCTGGCCTGTAATTTTTCTTTCAAGGATGATAATTTGTGTGTTGT
TTGATTTGTTTATATTTTACATCTCTGTAGTTTTATTTTTAGAAGTTGTGAGATATTGGA
TGTGTGGCTATTTTTCCTTTCTCTGTATTCTTTATGAAACATAACTTTTGAAAAACCTAT
GTATTATTCATACAGCTTTGGTTTGTATATTCTGTATAGCCTAACTACACACATCAAAAT
GTATGTCAACCAAGTGTTTAGAATGAAATTATAAGTGTTTAAGTCCAAATAAAGCATGTG
ATGTGGAATAATCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites ECoRI-NOT     
ACCN NM_177969
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_177969.2, NP_808908.1
RefSeq Size 1776 bp
RefSeq ORF 579 bp
Locus ID 5495
UniProt ID O75688
Protein Families Druggable Genome, Phosphatase, Stem cell - Pluripotency
Protein Pathways MAPK signaling pathway
Gene Summary The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (3) lacks an alternate exon, and it thus differs in its 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (3) is shorter at the N-terminus, compared to isoform 1.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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