United States
Germany
Japan
United Kingdom
China
STK38 (NM_007271) Human Untagged Clone
CAT＃: SC323502
STK38 (untagged)-Kinase deficient mutant (K118M) of Human serine/threonine kinase 38 (STK38)
CNY 3,656.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | NDR; NDR1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC323502 sequence for NM_007271 edited (data generated by NextGen Sequencing)
ATGGCAATGACAGGCTCAACACCTTGCTCATCCATGAGTAACCACACAAAGGAAAGGGTG ACAATGACCAAAGTGACACTGGAGAATTTTTATAGCAACCTTATCGCTCAACATGAAGAA CGAGAAATGAGACAAAAGAAGTTAGAAAAGGTGATGGAAGAAGAAGGCCTAAAAGATGAG GAGAAACGACTCCGGAGATCAGCACATGCTCGGAAGGAAACAGAGTTTCTTCGTTTGAAG AGAACAAGACTTGGATTGGAAGATTTTGAGTCCTTAAAAGTAATAGGCAGAGGAGCATTT GGTGAGGTACGGCTTGTTCAGAAGAAAGATACGGGACATGTGTATGCAATGATGATACTC CGTAAAGCAGATATGCTTGAAAAAGAGCAGGTTGGCCACATTCGTGCGGAGCGTGACATT CTAGTGGAGGCAGACAGTTTGTGGGTTGTGAAAATGTTCTATAGTTTTCAGGATAAGCTA AACCTCTACCTAATCATGGAGTTCCTGCCTGGAGGGGACATGATGACCTTGTTGATGAAA AAAGACACTCTGACAGAAGAGGAGACTCAGTTTTATATAGCAGAAACAGTATTAGCCATA GACTCTATTCACCAACTTGGATTCATCCACAGAGACATCAAACCAGACAACCTTCTTTTG GACAGCAAGGGCCATGTGAAACTTTCTGACTTTGGTCTTTGCACAGGACTGAAAAAAGCA CATAGGACAGAATTTTATAGGAATCTGAACCACAGCCTCCCCAGTGATTTCACTTTCCAG AACATGAATTCCAAAAGGAAAGCAGAAACCTGGAAAAGAAATAGACGTCAGCTAGCCTTC TCCACAGTAGGCACTCCTGACTACATTGCTCCTGAGGTGTTCATGCAGACCGGGTACAAC AAGCTCTGTGATTGGTGGTCGCTTGGGGTGATCATGTATGAGATGCTCATCGGCTACCCA CCTTTCTGTTCTGAGACCCCTCAAGAGACATATAAGAAGGTGATGAACTGGAAAGAAACT TTGACTTTTCCTCCAGAAGTTCCCATCTCTGAGAAAGCCAAGGATCTAATTTTGAGGTTC TGCTGTGAATGGGAACATAGAATTGGAGCTCCTGGAGTTGAGGAAATAAAAAGTAACTCT TTTTTTGAAGGCGTTGACTGGGAACATATCAGAGAGAGACCTGCTGCAATATCTATTGAA ATCAAAAGCATTGATGATACCTCAAACTTCGATGAGTTTCCAGAATCTGATATTCTTAAG CCAACAGTGGCCACAAGTAATCATCCTGAGACTGACTACAAGAACAAAGACTGGGTCTTC ATCAATTACACGTACAAGCGCTTTGAGGGCCTGACTGCAAGGGGGGCAATACCTTCCTAC ATGAAAGCAGCAAAATAG Clone variation with respect to NM_007271.2 353 a=>t;354 a=>g >OriGene 5' read for mutant NM_007271 unedited
CCCGCCGTTGAGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAA CCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTGGGCTCTGCCAT GGCAATGACAGGCTCAACACCTTGCTCATCCATGAGTAACCACACAAAGGAAAGGGTGACAATGACCAAA GTGACACTGGAGAATTTTTATAGCAACCTTATCGCTCAACATGAAGAACGAGAAATGAGACAAAAGAAGT TAGAAAAGGTGATGGAAGAAGAAGGCCTAAAAGATGAGGAGAAACGACTCCGGAGATCAGCACATGCTCG GAAGGAAAACAGAGTTTCTTCGTTTGAAGAAGAACAAGACTTTGGATGGGAAGATTTTGAGTCCTTAAAA GTAATAGGCAGAGGAGCATTTGGTGAGGTACGGTTGTTCAGAGAAAGATCCGGGACAGGTGTATGCAATG AATGATACTCGTAAACAAATTGCTTAAAAGAACAGTTGGCCAATCGGCGGACTGCTTCATGGGAGCAAAG TGGGTTGGAAAGTCTATTTCGGAAGCTACCTACAACTGGATTCCGCTGGGAAGGAACTGTGTAAAAACCT GCAAGAAACGTTTTAGAACGTTCTATCTTCCATGGATCCGGACTAACAACTTTTGCAAGGCGTGACTGCC TGGTTCGAGCTGAAGCCTGCACATTAAGTTGCACGCGCAGATCTCAGGTCCCCAGCACTGGAAAGCGTAG CTCTGAGGCCTGGC >SC323502 kinase domain raw sequence. By performing BLASTX analysis with this sequence against NCBI refernce protein database, you can confirm the presence of the kinase-deficient mutation
TMGMTTGGATTGGAGWTTTGAGTCCTTAAAGTAATAGGCAGAGGAGCATTTGGTGAGGTACGGCTTGTTC AGAAGAAAGATACGGGACATGTGTATGCAATGATGATACTCCGTAAAGCAGATATGCTTGAAAAAGAGCA GGTTGGCCACATTCGTGCGGAGCGTGACATTCTAGTGGAGGCAGACAGTTTGTGGGTTGTGAAAATGTTC TATAGTTTTCAGGATAAGCTAAACCTCTACCTAATCATGGAGTTC |
| Restriction Sites | Please inquire |
| ACCN | NM_007271 |
| Insert Size | 3500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This kinase-deficient mutant clone was generated by created by site-directed mutagenesis from the corresponding wild-type clone. See details in "Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling." Cell. 2008 May p536-548. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_007271.2, NP_009202.1 |
| RefSeq Size | 3593 bp |
| RefSeq ORF | 1398 bp |
| Locus ID | 11329 |
| UniProt ID | Q15208 |
| Domains | pkinase, TyrKc, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Gene Summary | This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015] Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204133 | STK38 (Myc-DDK-tagged)-Human serine/threonine kinase 38 (STK38) |
CNY 3,656.00 |
|
| RC204133L1 | Lenti ORF clone of Human serine/threonine kinase 38 (STK38), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204133L2 | Lenti ORF clone of Human serine/threonine kinase 38 (STK38), mGFP tagged |
CNY 5,890.00 |
|
| RC204133L3 | Lenti ORF clone of Human serine/threonine kinase 38 (STK38), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204133L4 | Lenti ORF clone of Human serine/threonine kinase 38 (STK38), mGFP tagged |
CNY 5,890.00 |
|
| RG204133 | STK38 (tGFP-tagged) - Human serine/threonine kinase 38 (STK38) |
CNY 4,370.00 |
|
| SC115629 | STK38 (untagged)-Human serine/threonine kinase 38 (STK38) |
CNY 2,950.00 |
