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FER (NM_005246) Human Untagged Clone
CAT＃: SC323485
FER (untagged)-Kinase deficient mutant (K591M) of Human fer (fps/fes related) tyrosine kinase (FER)
CNY 6,032.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | p94-Fer; PPP1R74; TYK3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_005246, the custom clone sequence may differ by one or more nucleotides
ATGGGGTTTGGGAGTGACCTGAAGAATTCACATGAAGCAGTGTTAAAATTGCAAGACTGGGAATTACGGT TACTGGAAACAGTAAAGAAATTTATGGCCCTGAGAATAAAAAGTGATAAAGAATATGCATCTACTTTACA GAACCTTTGTAATCAAGTTGATAAGGAAAGTACTGTCCAAATGAATTATGTCAGCAACGTATCCAAGTCT TGGCTACTTATGATTCAGCAGACAGAACAACTTAGTAGGATAATGAAGACACATGCAGAGGACTTGAACT CTGGACCTTTACACAGGCTCACCATGATGATTAAGGACAAGCAGCAGGTGAAGAAAAGTTACATAGGTGT TCATCAGCAGATAGAGGCAGAGATGATCAAGGTTACCAAAACAGAATTGGAGAAGTTAAAATGCAGCTAT AGACAATTAATAAAAGAAATGAATTCTGCCAAAGAGAAATATAAAGAAGCTTTAGCTAAAGGGAAGGAAA CTGAAAAGGCCAAGGAACGATACGACAAAGCCACAATGAAACTTCATATGTTGCACAATCAGTATGTATT GGCGTTGAAAGGGGCACAGCTCCATCAGAATCAGTATTATGATATCACACTTCCCCTGCTTCTGGACTCC TTACAAAAGATGCAAGAAGAAATGATAAAAGCACTCAAAGGTATATTTGATGAATACAGCCAGATAACCA GTCTTGTCACAGAGGAAATAGTGAATGTCCATAAAGAGATTCAAATGTCGGTTGAACAGATAGATCCTAG TACAGAATACAATAATTTCATAGATGTTCACAGAACAACGGCTGCTAAAGAACAAGAAATAGAGTTTGAT ACTTCCTTACTGGAAGAAAATGAAAATCTTCAGGCAAATGAGATCATGTGGAATAACTTAACAGCAGAAA GTTTGCAAGTAATGTTGAAAACGTTAGCGGAAGAACTTATGCAAACACAGCAGATGCTTTTAAACAAGGA GGAGGCTGTTTTGGAGTTAGAGAAGAGAATTGAAGAATCTTCTGAAACTTGTGAGAAGAAGTCTGATATT GTGCTTCTGCTAAGCCAAAAACAGGCACTTGAAGAACTGAAACAGTCAGTCCAGCAGCTGAGATGCACTG AAGCAAAGTTTTCAGCACAGAAGGAATTACTAGAGCAAAAAGTGCAAGAAAATGATGGGAAAGAGCCACC TCCAGTAGTAAATTATGAAGAAGATGCACGATCAGTTACATCTATGGAAAGAAAGGAGAGGCTATCCAAA TTTGAATCTATTCGTCATTCAATTGCTGGAATAATTAGGTCTCCAAAATCTGCACTGGGCTCTTCAGCAC TTTCTGATATGATCTCCATCAGTGAGAAGCCTTTGGCAGAACAGGACTGGTACCATGGTGCAATTCCCAG AATAGAAGCTCAAGAACTGTTAAAAAAACAAGGAGACTTTTTGGTGCGAGAGAGTCATGGGAAACCTGGT GAATATGTCCTTTCTGTATATTCTGATGGACAGAGGAGACATTTTATCATACAATATGTTGATAACATGT ATCGATTCGAGGGCACTGGGTTTTCAAACATTCCTCAACTTATAGATCATCACTATACAACAAAACAGGT CATCACTAAGAAATCAGGTGTAGTTCTGCTGAATCCTATTCCTAAGGACAAGAAATGGATTCTCAGTCAT GAAGATGTCATATTGGGAGAATTACTGGGCAAGGGAAATTTTGGTGAAGTATATAAGGGCACATTAAAGG ATAAAACTTCTGTTGCTGTTAAAACATGTAAAGAAGATCTTCCTCAGGAATTGAAAATAAAATTTTTACA AGAAGCCAAAATTCTCAAGCAATATGATCATCCCAATATTGTCAAACTTATAGGAGTTTGCACACAAAGA CAGCCTGTCTACATCATTATGGAACTGGTTTCAGGAGGTGATTTCCTCACCTTTCTGAGAAGGAAGAAGG ATGAACTAAAACTCAAACAGTTAGTGAAATTTTCATTAGACGCTGCTGCTGGTATGTTGTATCTCGAGAG TAAAAACTGTATACACAGGGACCTTGCTGCAAGAAACTGCCTGGTAGGTGAAAATAATGTTCTGAAAATC AGTGACTTTGGAATGTCTCGTCAAGAGGATGGTGGAGTGTATTCATCTTCTGGCTTAAAGCAGATTCCCA TTAAATGGACAGCACCGGAAGCTCTTAATTATGGGAGATACAGTTCAGAGAGTGACGTGTGGAGCTTTGG CATCCTTCTCTGGGAGACCTTCAGCTTAGGGGTTTGTCCGTACCCTGGAATGACAAATCAGCAAGCAAGA GAGCAAGTAGAAAGAGGATACCGGATGTCAGCTCCCCAGCACTGTCCAGAGGATATTTCCAAAATCATGA TGAAGTGTTGGGATTATAAACCTGAAAATCGCCCTAAGTTCAGTGAACTTCAGAAAGAGCTCACTATCAT CAAGAGAAAACTCACATAG >OriGene 5' read for mutant NM_005246 unedited
ACCGCCGTTGAGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAA CCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTTCTAGATATGTG CTGATTAGAAGGCTCACTTGTGCAGTGTGGAGGATAACCAGTGCCTTACAAAATGGGGTTTGGGAGTGAC CTGAAGAATTCACATGAAGCAGTGTTAAAATTGCAAGACTGGGAATTACGGTTACTGGAAACAGTAAAGA AATTTATGGCCCTGAGAATAAAAAGTGATAAAGAATATGCATCTACTTTTACAGAACCTTTGTAATCAAG TGTGATAAAGGAAAGTACTGTCCCAAATGAATTTATGTCAGCAACGTATCCAAGTCTTGCCTACTTTATG AATTCAGCAGACAGAACCAACTTTAGTAGGATAATGAAGGACCACATGGCCAAAGGACTTGACCTCTGAA CCTTTACCCAGGCTAACAAGGAGGATTAAGGACAGGCCGAAGGGGAAAAAAAGTTACTAAGTGTGTTTTC CAGCAGTAGAGGGGCGAAATATATCAAGGGTAACCAAAACAAATTGAGAAATTTAAATGCGCCTTTTACA CATTTTATAAGAGATGTGATTTCTGCCAGAGAAAAATATAGAGACGCTTTCCCTAAGGGAGAGGAACTGA AAGCGCCAGGGCACGACGCACAGCCCATGGGACTCTCATGTGTGCCAACACCATTATATGCGTGTAAAGG GCACACTCTCTCAATAGTATTATGATATCCCTTCTCCGTGCTGGCTCTCACATGCGCGAGTGTGTAAGCC TCAAGAGTTTGTGAAACGGCGGATACGCTGTTCGAGGAGATATGATCAAGATCACTGCCTGTGACTGATC ATCGGACACACGTCCATGCCAGCTGTGGACACAGGAAAAGTGAGTACTTCTATCGGAGA >SC323485 kinase domain raw sequence. By performing BLASTX analysis with this sequence against NCBI refernce protein database, you can confirm the presence of the kinase-deficient mutation
GTKKWWKYMWWTTGKGRGAWTACTGGGCAGGGAATTWTGGTGAAGTATATAAGGGCACATTAAASSMTAW YAWKTCTGTTGCTGTTATGACATGTAAAGAAGATCTTCCTCAGGAATTGAAAATAAAATTTTTACAAGAA GCCAAAATTCTCAAGCAATATGATCATCCCAATATTGTCAAACTTATAGGAGTTTGCACACAAAKACAGC CTGTCTACRTCATTATGGAACTGGTTTCAGGARGTGATTTCCTCA |
| Restriction Sites | Please inquire |
| ACCN | NM_005246 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_005246.1. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005246.1, NP_005237.1 |
| RefSeq Size | 2950 bp |
| RefSeq ORF | 2469 bp |
| Locus ID | 2241 |
| UniProt ID | P16591 |
| Domains | pkinase, SH2, FCH, TyrKc, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Adherens junction |
| Gene Summary | The protein encoded by this gene is a member of the FPS/FES family of non-transmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Apr 2015] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a, also known as p94-Fer or FerS). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219948 | FER (Myc-DDK-tagged)-Human fer (fps/fes related) tyrosine kinase (FER) |
CNY 6,024.00 |
|
| RC219948L1 | Lenti-ORF clone of FER (Myc-DDK-tagged)-Human fer (fps/fes related) tyrosine kinase (FER) |
CNY 7,700.00 |
|
| RC219948L2 | Lenti-ORF clone of FER (mGFP-tagged)-Human fer (fps/fes related) tyrosine kinase (FER) |
CNY 7,700.00 |
|
| RC219948L3 | Lenti-ORF clone of FER (Myc-DDK-tagged)-Human fer (fps/fes related) tyrosine kinase (FER) |
CNY 7,700.00 |
|
| RC219948L4 | Lenti-ORF clone of FER (mGFP-tagged)-Human fer (fps/fes related) tyrosine kinase (FER) |
CNY 7,700.00 |
|
| RG219948 | FER (tGFP-tagged) - Human fer (fps/fes related) tyrosine kinase (FER) |
CNY 7,624.00 |
|
| SC310093 | FER (untagged)-Human fer (fps/fes related) tyrosine kinase (FER) |
CNY 6,032.00 |
