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Filamin C (FLNC) (NM_001127487) Human Untagged Clone
CAT＃: SC323318
FLNC (untagged)-Human filamin C, gamma (FLNC), transcript variant 2
CNY 51,870.00
货期*
详询
规格
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经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ABP-280; ABP280A; ABPA; ABPL; CMH26; FLN2; MFM5; MPD4; RCM5 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001127487, the custom clone sequence may differ by one or more nucleotides
ATGATGAACAACAGCGGCTACTCAGACGCCGGCCTCGGCCTGGGCGATGAGACAGACGAG ATGCCGTCCACGGAGAAGGACCTGGCGGAGGACGCGCCGTGGAAGAAGATCCAGCAGAAC ACATTCACGCGCTGGTGCAATGAGCACCTCAAGTGCGTGGGCAAGCGCCTGACCGACCTG CAGCGCGACCTCAGCGACGGGCTCCGGCTCATCGCGCTGCTCGAGGTGCTCAGCCAGAAG CGCATGTACCGCAAGTTCCATCCGCGCCCCAACTTCCGCCAAATGAAGCTGGAGAACGTG TCCGTGGCCCTCGAGTTCCTCGAGCGCGAGCACATCAAGCTCGTGTCCATAGACAGCAAG GCCATCGTGGATGGGAACCTGAAGCTGATCCTGGGCCTGATCTGGACGCTGATCCTGCAC TACTCCATCTCCATGCCCATGTGGGAGGATGAAGATGATGAGGATGCCCGCAAACAGACG CCCAAGCAGCGGCTGCTTGGCTGGATCCAGAACAAGGTGCCCCAGCTGCCCATCACCAAC TTCAACCGTGACTGGCAGGACGGCAAAGCTCTGGGCGCCCTGGTGGACAACTGCGCCCCC GGTCTCTGCCCCGACTGGGAGGCCTGGGACCCCAACCAGCCCGTGGAGAACGCCCGGGAG GCCATGCAGCAGGCCGACGACTGGCTTGGGGTGCCCCAGGTCATTGCCCCTGAGGAGATT GTGGACCCCAACGTGGATGAGCATTCTGTTATGACCTACCTGTCCCAGTTCCCCAAGGCC AAGCTCAAACCTGGTGCCCCTGTTCGATCCAAGCAGCTGAACCCCAAGAAAGCCATCGCC TATGGGCCTGGCATCGAGCCACAGGGCAACACCGTGCTGCAGCCTGCCCACTTCACCGTG CAGACGGTGGACGCGGGCGTGGGCGAGGTGCTGGTCTACATCGAGGACCCTGAAGGCCAC ACCGAGGAGGCTAAGGTGGTTCCCAACAATGACAAGGATCGCACCTATGCTGTCTCCTAT GTGCCCAAGGTCGCTGGGTTACACAAGGTGACCGTGCTCTTTGCTGGCCAGAACATTGAA CGCAGTCCCTTTGAGGTGAACGTGGGCATGGCCCTGGGAGATGCCAACAAGGTGTCAGCC CGTGGCCCTGGCCTGGAACCTGTGGGCAATGTGGCCAACAAACCCACCTACTTTGACATC TACACTGCGGGGGCCGGCACTGGCGATGTTGCTGTGGTGATCGTGGACCCACAGGGCCGG CGGGACACAGTGGAGGTGGCCCTGGAGGACAAGGGTGACAGCACGTTCCGCTGCACATAC AGACCTGCCATGGAGGGGCCACATACCGTGCATGTGGCCTTTGCGGGTGCCCCCATCACC CGCAGTCCCTTCCCTGTCCATGTGTCGGAAGCCTGTAACCCCAACGCCTGCCGCGCCTCT GGGCGAGGCCTGCAGCCCAAGGGTGTTCGCGTGAAAGAGGTGGCTGACTTCAAGGTGTTT ACCAAGGGTGCCGGCAGCGGGGAGCTCAAGGTCACGGTCAAGGGGCCAAAGGGCACAGAG GAGCCAGTGAAGGTGCGGGAGGCTGGGGATGGTGTGTTCGAGTGCGAGTACTACCCGGTG GTGCCTGGGAAGTATGTGGTGACCATCACGTGGGGCGGCTACGCCATCCCTCGCAGCCCC TTTGAGGTACAGGTGAGCCCAGAGGCAGGAGTGCAAAAGGTCCGGGCCTGGGGTCCTGGT TTGGAGACTGGCCAGGTGGGCAAGTCAGCCGATTTTGTGGTGGAAGCCATTGGCACCGAG GTGGGGACACTGGGCTTCTCCATCGAGGGGCCCTCACAAGCCAAGATCGAATGTGACGAC AAGGGGGATGGCTCCTGCGATGTGCGGTACTGGCCCACGGAGCCTGGGGAGTACGCTGTG CACGTCATCTGTGACGATGAGGACATCCGAGACTCACCCTTCATTGCCCACATCCTGCCC GCCCCACCTGACTGCTTCCCAGATAAGGTGAAGGCCTTTGGGCCTGGCCTGGAGCCTACC GGCTGCATCGTGGACAAGCCCGCTGAGTTCACCATTGATGCTCGTGCAGCTGGCAAGGGA GACCTGAAGCTCTATGCCCAGGACGCCGACGGCTGTCCCATCGACATCAAGGTGATCCCC AACGGCGACGGCACCTTCCGCTGCTCCTACGTGCCCACCAAGCCCATTAAGCACACCATC ATCATCTCCTGGGGAGGCGTAAACGTGCCCAAGAGCCCCTTCCGGGTGAACGTGGGCGAG GGCAGCCACCCCGAGCGGGTAAAGGTGTACGGCCCCGGAGTGGAGAAGACAGGCCTCAAG GCCAATGAGCCCACCTACTTCACGGTGGACTGCAGCGAGGCGGGGCAAGGCGACGTGAGC ATCGGCATCAAGTGCGCCCCAGGCGTGGTGGGCCCTGCAGAGGCTGACATTGACTTCGAC ATCATCAAGAATGACAACGACACCTTCACCGTCAAGTACACGCCACCAGGGGCGGGCCGC TACACCATCATGGTGCTGTTTGCCAACCAGGAGATCCCCGCCAGCCCCTTCCACATCAAG GTGGACCCATCCCACGATGCCAGCAAAGTCAAGGCCGAGGGCCCTGGGCTGAATCGCACA GGTGTGGAAGTCGGGAAGCCCACCCACTTCACGGTGCTGACCAAGGGAGCCGGCAAGGCC AAGCTGGATGTGCAGTTTGCAGGGACAGCCAAGGGCGAGGTTGTGCGGGACTTTGAGATC ATAGACAACCATGACTACTCCTACACTGTCAAGTACACCGCTGTCCAGCAGGGCAACATG GCAGTGACAGTGACTTATGGCGGGGACCCTGTCCCCAAGAGCCCCTTTGTGGTGAATGTG GCACCCCCGCTGGACCTCAGCAAAATCAAAGTTCAGGGCCTTAATAGCAAGGTGGCTGTG GGACAGGAACAAGCATTCTCTGTGAACACACGAGGGGCTGGCGGTCAGGGCCAACTGGAT GTGCGGATGACTTCGCCCTCTCGCCGGCCCATCCCCTGCAAGCTGGAGCCAGGCGGTGGA GCGGAAGCCCAGGCTGTGCGCTACATGCCCCCGGAGGAGGGGCCCTACAAGGTGGATATC ACCTACGATGGTCACCCGGTGCCTGGCAGCCCGTTTGCTGTGGAGGGTGTCCTGCCCCCT GATCCCTCCAAGGTCTGTGCTTATGGCCCGGGTCTCAAGGGTGGACTGGTAGGCACCCCC GCGCCATTCTCCATCGACACCAAGGGGGCTGGCACAGGTGGCCTGGGGCTGACCGTAGAG GGCCCCTGCGAGGCCAAGATCGAGTGCCAGGACAATGGTGATGGCTCATGTGCTGTCAGC TACCTGCCCACGGAGCCTGGCGAGTACACCATCAACATCCTGTTTGCTGAGGCCCACATC CCTGGCTCGCCCTTCAAAGCCACCATTCGGCCTGTGTTTGACCCGAGCAAGGTGCGGGCC AGTGGACCGGGCCTGGAGCGCGGCAAGGTCGGTGAGGCAGCCACCTTCACTGTGGACTGC TCAGAGGCAGGCGAGGCGGAGCTGACCATTGAGATCCTGTCGGATGCCGGGGTCAAGGCC GAGGTGCTGATCCACAACAACGCGGATGGCACCTACCACATCACCTACAGCCCTGCCTTC CCTGGCACCTACACCATTACCATCAAGTATGGCGGGCATCCCGTGCCCAAATTCCCCACC CGTGTCCATGTGCAGCCTGCGGTCGATACCAGTGGCGTCAAGGTCTCAGGGCCTGGTGTT GAGCCACACGGTGTCCTGCGGGAGGTGACCACTGAGTTCACTGTGGATGCAAGATCCCTA ACAGCCACAGGCGGCAACCACGTGACGGCTCGTGTGCTCAACCCCTCGGGGGCCAAGACA GACACCTATGTGACAGACAATGGGGACGGCACCTACCGAGTGCAGTACACCGCCTACGAG GAGGGCGTGCATCTGGTGGAGGTCCTGTATGATGAGGTCGCTGTGCCCAAGAGCCCCTTC CGAGTGGGCGTGACCGAGGGCTGTGATCCCACCCGCGTCCGAGCCTTCGGGCCAGGCCTG GAGGGTGGCTTGGTCAACAAGGCCAACCGATTCACTGTGGAGACCAGGGGAGCGGGCACC GGGGGCCTTGGCCTAGCCATCGAGGGTCCCTCGGAAGCCAAGATGTCCTGCAAGGACAAC AAGGATGGTAGCTGCACCGTGGAGTACATCCCCTTCACTCCTGGAGACTATGACGTCAAC ATCACCTTCGGGGGGCGGCCCATCCCAGGGAGCCCGTTCCGCGTGCCAGTGAAGGATGTG GTGGACCCTGGGAAGGTGAAGTGCTCAGGGCCAGGGCTGGGGGCTGGTGTCAGGGCCCGG GTTCCTCAGACCTTCACAGTGGACTGCAGTCAAGCTGGCCGGGCGCCCCTGCAGGTGGCT GTGCTGGGCCCCACAGGTGTGGCCGAGCCTGTGGAGGTGCGGGACAATGGAGATGGCACC CACACTGTCCACTACACCCCAGCCACTGACGGGCCCTACACGGTAGCCGTCAAGTATGCT GACCAGGAGGTGCCACGCAGCCCCTTCAAGATCAAGGTCCTCCCAGCTCATGATGCCAGC AAGGTGCGGGCCAGCGGCCCAGGCCTCAACGCCTCTGGCATCCCTGCCAGCCTGCCTGTG GAGTTCACCATCGACGCACGGGACGCGGGCGAGGGGTTGCTCACTGTCCAGATCTTGGAC CCCGAGGGTAAGCCCAAGAAGGCCAACATCCGGGACAATGGGGATGGCACGTACACTGTG TCCTACCTGCCGGACATGAGTGGCCGGTACACCATCACCATCAAGTATGGCGGTGATGAG ATCCCCTACTCGCCCTTCCGCATCCATGCTCTGCCCACTGGGGATGCCAGCAAGTGCCTC GTCACAGTGTCCATTGGAGGCCATGGCCTGGGTGCCTGCCTGGGCCCTCGAATCCAGATT GGGCAGGAGACGGTGATCACGGTGGATGCCAAGGCAGCCGGTGAGGGGAAGGTGACATGC ACGGTGTCCACGCCGGATGGGGCAGAGCTCGATGTGGATGTGGTTGAGAACCATGACGGT ACCTTTGACATCTACTACACAGCGCCCGAGCCGGGCAAGTACGTCATCACCATCCGCTTC GGGGGTGAGCACATCCCCAACAGCCCCTTCCACGTGCTGGCCACAGAGGAGCCAGTGGTG CCTGTGGAGCCAATGGAGTCCATGCTGAGGCCCTTCAACCTGGTCATCCCCTTCGCGGTG CAGAAAGGGGAGCTCACAGGAGAGGTGCGGATGCCCTCGGGGAAGACGGCACGGCCCAAC ATCACCGACAACAAGGACGGCACCATCACGGTGAGGTATGCACCCACTGAGAAAGGCCTG CACCAGATGGGGATCAAGTATGACGGCAACCACATCCCTGGGAGCCCCTTACAGTTCTAT GTGGATGCCATCAACAGCCGCCATGTCAGTGCCTATGGGCCAGGCCTGAGCCATGGCATG GTCAACAAGCCAGCCACCTTCACTATTGTCACCAAAGATGCTGGAGAAGGGGGTCTGTCA CTGGCCGTGGAGGGCCCATCCAAGGCAGAGATCACCTGTAAGGACAACAAGGATGGCACC TGCACCGTGTCCTATCTGCCGACTGCGCCTGGAGACTACAGCATCATCGTGCGCTTCGAT GACAAGCACATCCCGGGGAGCCCCTTCACAGCCAAGATCACAGGTGATGACTCCATGAGG ACCTCACAGCTGAATGTGGGCACCTCCACGGACGTGTCACTGAAGATCACCGAGAGTGAT CTGAGCCAGCTGACCGCCAGCATCCGTGCCCCCTCGGGCAACGAGGAGCCCTGCCTGCTG AAGCGCCTGCCCAACCGGCACATTGGGATCTCCTTCACCCCCAAGGAGGTCGGGGAGCAC GTGGTGAGCGTGCGCAAGAGTGGCAAGCATGTCACCAACAGCCCCTTCAAGATCCTGGTG GGGCCATCTGAGATCGGGGACGCCAGCAAGGTGCGGGTCTGGGGCAAGGGGCTTTCCGAG GGACACACATTCCAGGTGGCAGAGTTCATCGTGGACACTCGCAATGCAGGTTATGGGGGC TTGGGGCTGAGTATTGAAGGCCCAAGCAAGGTGGACATCAACTGTGAGGACATGGAGGAC GGGACATGCAAAGTCACCTACTGCCCCACCGAGCCCGGCACCTACATCATCAACATCAAG TTTGCTGACAAGCACGTGCCTGGAAGCCCCTTCACTGTGAAGGTGACCGGCGAGGGCCGC ATGAAGGAGAGCATCACCCGGCGGAGACAGGCACCTTCCATCGCCACCATCGGCAGCACC TGTGACCTCAACCTCAAGATCCCAGGAAACTGGTTCCAGATGGTGTCTGCCCAGGAGCGC CTGACACGCACCTTCACACGCAGCAGCCACACCTACACCCGCACGGAGCGCACGGAGATC AGCAAGACGCGGGGCGGGGAGACAAAGCGCGAGGTGCGGGTGGAGGAGTCCACCCAGGTC GGCGGGGACCCCTTCCCTGCTGTGTTTGGGGACTTCCTGGGCCGGGAGCGCCTGGGATCC TTCGGCAGCATCACCCGGCAGCAGGAGGGTGAGGCCAGCTCTCAGGACATGACTGCACAG GTGACCAGCCCATCGGGCAAGGTGGAAGCCGCAGAGATCGTCGAGGGCGAGGACAGCGCC TACAGCGTGCGCTTTGTGCCCCAGGAAATGGGGCCCCATACGGTCGCTGTCAAGTACCGT GGCCAGCACGTGCCCGGCAGCCCCTTTCAGTTCACTGTGGGGCCGCTGGGTGAAGGTGGT GCCCACAAGGTGCGGGCCGGAGGCACAGGGCTGGAGCGAGGTGTGGCCGGCGTGCCAGCC GAGTTCAGCATCTGGACCCGGGAGGCTGGCGCTGGGGGCCTGTCCATTGCTGTGGAGGGT CCTAGCAAAGCGGAGATTGCATTTGAGGATCGCAAAGATGGCTCCTGCGGCGTCTCCTAT GTCGTCCAGGAACCAGGTGACTATGAGGTCTCCATCAAGTTCAATGATGAGCACATCCCA GACAGCCCCTTTGTGGTGCCTGTGGCCTCCCTCTCGGATGACGCTCGCCGTCTCACTGTC ACCAGCCTCCAGGAGACGGGGCTCAAGGTGAACCAGCCAGCGTCCTTTGCCGTGCAGCTG AACGGTGCCCGGGGCGTGATTGATGCCCGGGTGCACACACCCTCGGGGGCTGTGGAGGAG TGCTACGTCTCTGAGCTGGACAGTGACAAGCACACCATCCGCTTCATCCCCCACGAGAAT GGCGTCCACTCCATCGATGTCAAGTTCAACGGTGCCCACATCCCTGGAAGTCCCTTCAAG ATCCGCGTTGGGGAGCAGAGCCAGGCTGGGGACCCAGGCTTGGTGTCAGCCTACGGTCCT GGGCTCGAGGGAGGCACTACCGGTGTGTCATCAGAGTTCATCGTGAACACCCTGAATGCC GGCTCGGGGGCCTTGTCTGTCACCATTGATGGCCCCTCCAAGGTGCAGCTGGACTGTCGG GAGTGTCCTGAGGGCCATGTGGTCACTTATACTCCCATGGCCCCTGGCAACTACCTCATT GCCATCAAGTACGGTGGCCCCCAGCACATCGTGGGCAGCCCCTTCAAGGCCAAGGTCACT GGTCCGAGGCTGTCCGGAGGCCACAGCCTTCACGAAACATCCACGGTTCTGGTGGAGACT GTGACCAAGTCCTCCTCAAGCCGGGGCTCCAGCTACAGCTCCATCCCCAAGTTCTCCTCA GATGCCAGCAAGGTGGTGACTCGGGGCCCTGGGCTGTCCCAGGCCTTCGTGGGCCAGAAG AACTCCTTCACCGTGGACTGCAGCAAAGCAGGCACCAACATGATGATGGTGGGCGTGCAC GGCCCCAAGACCCCCTGTGAGGAGGTGTACGTGAAGCACATGGGGAACCGGGTGTACAAT GTCACCTACACTGTCAAGGAGAAAGGGGACTACATCCTCATTGTCAAGTGGGGTGACGAA AGTGTCCCTGGAAGCCCCTTCAAAGTCAAGGTCCCT |
| Restriction Sites | Please inquire |
| ACCN | NM_001127487 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001127487.1, NP_001120959.1 |
| RefSeq Size | 9050 bp |
| RefSeq ORF | 8079 bp |
| Locus ID | 2318 |
| UniProt ID | Q14315 |
| Protein Pathways | Focal adhesion, MAPK signaling pathway |
| Gene Summary | This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. |
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