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XPG (ERCC5) (NM_000123) Human Untagged Clone
CAT＃: SC322497
ERCC5 (untagged)-Human excision repair cross-complementing rodent repair deficiency, complementation group 5 (ERCC5)
CNY 8,264.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | COFS3; ERCC5-201; ERCM2; UVDR; XPG; XPGC |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for SC322497
TGCGGACCCACCAGCGAAGGCGGGAGGTGTCGCAGGGACATCTTCTGGCTGTTTCCGTCG
CCTGCGTGGCCCTTGCACCCCGGTCTTCCATTAGCGGCGCAGACGTTTGGGCCTAAGCGC TGGGCGAGGCGAGGCCCTGCCCCTCCCCGCCAACGGCCATTCTCTGGACCTGTCTTTCTT CCGGGAGGCGGTGACAGCTGCTGAGACGTGTTGCAGCCAGAGTCTCTCCGCTTTAATGCG CTCCCATTAGTGCCGTCCCCCACTGGAAAACCGTGGCTTCTGTATTATTTGCCATCTTTG TTGTGTAGGAGCAGGGAGGGCTTCCTCCCGGGGTCCTAGGCGGCGGTGCAGTCCGTCGTA GAAGAATTAGAGTAGAAGTTGTCGGGGTCCGCTCTTAGGACGCAGCCGCCTCATGGGGGT CCAGGGGCTCTGGAAGCTGCTGGAGTGCTCCGGGCGGCAGGTCAGCCCCGAAGCGCTGGA AGGGAAGATCCTGGCTGTTGATATTAGCATTTGGTTAAACCAAGCACTTAAAGGAGTCCG GGATCGCCACGGGAACTCAATAGAAAATCCTCATCTTCTCACTTTGTTTCATCGGCTCTG CAAACTCTTATTTTTTCGAATTCGTCCTATTTTTGTGTTTGATGGGGATGCTCCACTATT GAAGAAACAGACTTTGGTGAAGAGAAGGCAGAGAAAGGACTTAGCGTCCAGTGACTCCAG GAAAACGACAGAGAAGCTTCTGAAAACATTTTTGAAAAGACAAGCCATCAAAACTGCCTT CAGAAGCAAAAGAGATGAAGCACTACCCAGTCTTACCCAAGTTCGAAGAGAAAACGACCT CTATGTTTTGCCTCCTTTACAAGAGGAAGAAAAACACAGTTCAGAAGAGGAAGATGAAAA AGAATGGCAAGAAAGAATGAATCAAAAACAAGCATTACAGGAAGAGTTCTTTCATAATCC TCAAGCGATAGATATTGAGTCTGAGGACTTCAGCAGCCTGCCCCCTGAAGTAAAGCATGA AATCTTGACTGATATGAAAGAGTTCACCAAGCGCAGAAGAACATTATTTGAAGCAATGCC AGAGGAGTCTGATGACTTTTCACAGTACCAACTCAAAGGCTTGCTTAAAAAGAACTATCT GAACCAGCATATAGAACATGTCCAAAAGGAAATGAATCAGCAACATTCAGGACACATCCG AAGGCAGTATGAAGATGAAGGGGGCTTTCTGAAGGAGGTAGAGTCAAGGAGAGTGGTCTC TGAAGACACTTCACATTACATCTTGATAAAAGGTATTCAAGCTAAGACAGTTGCAGAAGT GGATTCAGAGTCTCTTCCTTCTTCCAGCAAAATGCACGGCATGTCTTTTGACGTGAAGTC ATCTCCATGTGAAAAACTGAAGACAGAGAAAGAGCCTGATGCTACCCCTCCTTCTCCAAG AACTTTACTAGCTATGCAAGCTGCCCTGCTGGGAAGTAGCTCAGAAGAGGAGCTGGAGAG TGAAAATCGAAGGCAGGCCCGTGGGAGGAACGCACCTGCTGCTGTAGACGAAGGCTCCAT ATCACCCCGGACTCTTTCAGCCATTAAGAGAGCTCTTGACGATGACGAAGATGTAAAAGT GTGTGCTGGGGATGATGTGCAGACGGGAGGGCCAGGAGCAGAAGAAATGCGTATAAACAG CTCCACCGAGAACAGTGATGAAGGACTTAAAGTGAGAGATGGAAAAGGAATACCGTTTAC TGCAACACTTGCGTCATCTAGTGTGAACTCTGCAGAGGAGCACGTAGCCAGCACTAATGA GGGGAGAGAGCCCACAGACTCAGTTCCAAAAGAACAAATGTCACTTGTTCACGTGGGGAC TGAAGCCTTTCCGATAAGTGATGAGTCTATGATTAAGGACAGAAAAGATCGGCTGCCTCT GGAGAGTGCAGTGGTTAGACATAGTGACGCACCTGGGCTCCCGAATGGAAGGGAACTGAC ACCGGCATCTCCAACTTGTACAAATTCTGTGTCAAAGAATGAAACACATGCTGAAGTGCT TGAGCAGCAGAACGAACTTTGCCCATATGAGAGTAAATTCGATTCTTCTCTTCTTTCAAG TGATGATGAAACAAAATGTAAACCGAATTCTGCTTCTGAAGTCATTGGCCCTGTCAGTTT GCAAGAAACAAGTAGCATAGTAAGTGTCCCTTCAGAGGCAGTAGATAATGTGGAAAATGT GGTGTCATTTAATGCTAAAGAGCATGAGAATTTTCTGGAAACCATCCAAGAACAGCAGAC CACTGAATCTGCAGGCCAGGATTTAATTTCCATTCCAAAGGCCGTGGAACCAATGGAAAT TGACTCGGAAGAAAGTGAATCTGATGGAAGTTTCATTGAAGTGCAAAGTGTGATTAGTGA TGAGGAACTTCAAGCAGAATTCCCTGAAACTTCCAAACCTCCCTCAGAACAAGGCGAAGA GGAACTGGTAGGAACTAGGGAGGGAGAAGCCCCTGCTGAGTCCGAGAGCCTCCTGAGGGA CAACTCTGAGAGGGACGACGTGGATGGTGAGCCACAGGAAGCTGAGAAAGATGCGGAAGA TTCGCTCCATGAATGGCAAGATATTAATTTGGAGGAGTTGGAAACTCTGGAGAGCAACCT CTTAGCACAGCAGAATTCACTGAAAGCTCAAAAACAGCAGCAAGAACGGATCGCTGCTAC TGTCACCGGACAGATGTTCCTGGAAAGCCAGGAACTCCTGCGCCTGTTCGGCATTCCCTA CATCCAGGCTCCCATGGAAGCAGAGGCGCAGTGCGCCATCCTGGACCTGACTGATCAGAC TTCCGGAACCATCACTGATGACAGTGATATCTGGCTGTTTGGAGCGCGGCATGTCTATAG AAACTTTTTTAATAAAAACAAGTTTGTAGAATATTATCAATATGTGGACTTTCACAATCA ATTGGGATTGGACCGGAATAAGTTAATAAATTTGGCTTATTTGCTTGGAAGTGATTATAC CGAAGGAATACCAACTGTGGGTTGTGTAACCGCCATGGAAATTCTCAATGAATTCCCTGG GCATGGCCTGGAACCTCTCCTAAAATTCTCAGAATGGTGGCATGAAGCTCAAAAAAATCC AAAGATAAGACCTAATCCTCATGACACCAAAGTGAAAAAAAAATTACGGACATTGCAACT CACCCCTGGCTTTCCTAACCCAGCTGTTGCCGAGGCCTACCTCAAACCCGTGGTGGATGA CTCGAAGGGATCCTTTCTGTGGGGGAAACCTGATCTCGACAAAATTAGAGAATTTTGTCA GCGGTATTTCGGCTGGAACAGAACGAAGACAGATGAATCTCTGTTTCCTGTATTAAAGCA ACTCGATGCCCAGCAGACACAGCTCCGAATTGATTCCTTCTTTAGATTAGCACAACAGGA GAAAGAAGATGCTAAACGTATTAAGAGCCAGAGACTAAACAGAGCTGTGACATGTATGCT AAGGAAAGAGAAAGAAGCAGCAGCCAGCGAAATAGAAGCAGTTTCTGTTGCCATGGAGAA AGAATTTGAGCTACTTGATAAGGCAAAACGAAAAACCCAGAAGAGAGGCATAACAAATAC CTTAGAAGAGTCATCAAGCCTGAAAAGAAAGAGGCTTTCAGATTCTAAACGAAAGAATAC ATGCGGTGGATTTTTGGGGGAGACCTGCCTCTCAGAATCATCTGATGGATCTTCAAGTGA AGATGCTGAAAGTTCATCTTTAATGAATGTACAAAGGAGAACAGCTGCGAAAGAGCCAAA AACCAGTGCTTCAGATTCGCAGAACTCAGTGAAGGAAGCTCCCGTGAAGAATGGAGGTGC GACCACCAGCAGCTCTAGTGATAGTGATGACGATGGAGGGAAAGAGAAGATGGTCCTCGT GACCGCCAGATCTGTGTTTGGGAAGAAAAGAAGGAAACTAAGACGTGCGAGGGGAAGAAA AAGGAAAACCTAATTAAAAAATATGTATCCTCTATAATTAGTTATGACAGCCATTTGTAA TGAATTTGTCGCAAAGACGTAATAAAATTAACTGGTAGCACGGTAAAAAAAAAAAAAAAA AA |
| Restriction Sites | Please inquire |
| ACCN | NM_000123 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000123.2, NP_000114.2 |
| RefSeq Size | 4100 bp |
| RefSeq ORF | 3561 bp |
| Locus ID | 2073 |
| UniProt ID | P28715 |
| Domains | HhH2, XPG_N, XPG_I |
| Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
| Protein Pathways | Nucleotide excision repair |
| Gene Summary | This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, cognitive disability, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. [provided by RefSeq, Feb 2011] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201994 | ERCC5 (Myc-DDK-tagged)-Human excision repair cross-complementing rodent repair deficiency, complementation group 5 (ERCC5) |
CNY 8,256.00 |
|
| RC201994L1 | Lenti ORF clone of Human excision repair cross-complementing rodent repair deficiency, complementation group 5 (ERCC5), Myc-DDK-tagged |
CNY 10,656.00 |
|
| RC201994L2 | Lenti ORF clone of Human excision repair cross-complementing rodent repair deficiency, complementation group 5 (ERCC5), mGFP tagged |
CNY 12,070.00 |
|
| RC201994L3 | Lenti ORF clone of Human excision repair cross-complementing rodent repair deficiency, complementation group 5 (ERCC5), Myc-DDK-tagged |
CNY 12,070.00 |
|
| RC201994L4 | Lenti ORF clone of Human excision repair cross-complementing rodent repair deficiency, complementation group 5 (ERCC5), mGFP tagged |
CNY 10,656.00 |
|
| RG201994 | ERCC5 (tGFP-tagged) - Human excision repair cross-complementing rodent repair deficiency, complementation group 5 (ERCC5) |
CNY 9,856.00 |
