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GUCY1B1 (NM_000857) Human Untagged Clone
CAT＃: SC322151
GUCY1B3 (untagged)-Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3)
CNY 4,616.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GC-S-beta-1; GC-SB3; GUC1B3; GUCB3; GUCSB3; GUCY1B3 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for SC322151
GTGGCCGCTGCCGCCTCTGCCTGGGTCCCTTCGGCCGTACCTCTGCGTGGGGGCTGCCTC
CCCGGCTCCCGGTGCAGACACCATGTACGGATTTGTGAATCACGCCCTGGAGTTGCTGGT GATCCGCAATTACGGCCCCGAGGTGTGGGAAGACATCAAAAAAGAGGCACAGTTAGATGA AGAAGGACAGTTTCTTGTCAGAATAATATATGATGACTCCAAAACTTATGATTTGGTTGC TGCTGCAAGCAAAGTCCTCAATCTCAATGCTGGAGAAATCCTCCAAATGTTTGGGAAGAT GTTTTTCGTCTTTTGCCAAGAATCTGGTTATGATACAATCTTGCGTGTCCTGGGCTCTAA TGTCAGAGAATTTCTACAGAACCTTGATGCTCTGCACGACCACCTTGCTACCATCTACCC AGGAATGCGTGCACCTTCCTTTAGGTGCACTGATGCAGAAAAGGGCAAAGGACTCATTTT GCACTACTACTCAGAGAGAGAAGGACTTCAGGATATTGTCATTGGAATCATCAAAACAGT GGCACAACAAATCCATGGCACTGAAATAGACATGAAGGTTATTCAGCAAAGAAATGAAGA ATGTGATCATACTCAATTTTTAATTGAAGAAAAAGAGTCAAAAGAAGAGGATTTTTATGA AGATCTTGACAGATTTGAAGAAAATGGTACCCAGGAATCACGCATCAGCCCATATACATT CTGCAAAGCTTTTCCTTTTCATATAATATTTGACCGGGACCTAGTGGTCACTCAGTGTGG CAATGCTATATACAGAGTTCTCCCCCAGCTCCAGCCTGGGAATTGCAGCCTTCTGTCTGT CTTCTCGCTGGTTCGTCCTCATATTGATATTAGTTTCCATGGGATCCTTTCTCACATCAA TACTGTTTTTGTATTGAGAAGCAAGGAAGGATTGTTGGATGTGGAGAAATTAGAATGTGA GGATGAACTGACTGGGACTGAGATCAGCTGCTTACGTCTCAAGGGTCAAATGATCTACTT ACCTGAAGCAGATAGCATACTTTTTCTATGTTCACCAAGTGTCATGAACCTGGACGATTT GACAAGGAGAGGGCTGTATCTAAGTGACATCCCTCTGCATGATGCCACACGCGATCTTGT TCTTTTGGGAGAACAATTTAGAGAGGAATACAAACTCACCCAAGAACTGGAAATCCTCAC TGACAGGCTACAGCTCACGTTAAGAGCCCTGGAAGATGAAAAGAAAAAGACAGACACATT GCTGTATTCTGTCCTTCCTCCGTCTGTTGCCAATGAGCTGCGGCACAAGCGTCCAGTGCC TGCCAAAAGATATGACAATGTGACCATCCTCTTTAGTGGCATTGTGGGCTTCAATGCTTT CTGTAGCAAGCATGCATCTGGAGAAGGAGCCATGAAGATCGTCAACCTCCTCAACGACCT CTACACCAGATTTGACACACTGACTGATTCCCGGAAAAACCCATTTGTTTATAAGGTGGA GACTGTTGGTGACAAGTATATGACAGTGAGTGGTTTACCAGAGCCATGCATTCACCATGC ACGATCCATCTGCCACCTGGCCTTGGACATGATGGAAATTGCTGGCCAGGTTCAAGTAGA TGGTGAATCTGTTCAGATAACAATAGGGATACACACTGGAGAGGTAGTTACAGGTGTCAT AGGACAGCGGATGCCTCGATACTGTCTTTTTGGGAATACTGTCAACCTCACAAGCCGAAC AGAAACCACAGGAGAAAAGGGAAAAATAAATGTGTCTGAATATACATACAGATGTCTTAT GTCTCCAGAAAATTCAGATCCACAATTCCACTTGGAGCACAGAGGCCCAGTGTCCATGAA GGGCAAAAAAGAACCAATGCAAGTTTGGTTTCTATCCAGAAAAAATACAGGAACAGAGGA AACAAAGCAGGATGATGACTGAATCTTGGATTGTGGGGTGAAGAGGAGTACAGACTAGGT TCCAGTTTTCTCCTAACACGTGCCAAGCCCAGGAGCAGTTCTTCCCTATGGATACAGATT TTCTTTTGTCCTTGTCCATTACCCCAAGACTTTCTTCTAGATATATCTCTCACTATCCGT TATTCAACCTTAGCTCTGCTTTCTATTACTTTTTAGGCTTTAGTATATTATCTAAAGTTT GGCTTTTGATGTGGATGATGTGAGCTTCATGTGTCTTAAAATCTACTACAAGCATTACCT AACATGGTGATCTGCAAGTAGTAGGCACCCAATAAATATTTGTTGAATTTAGTTAAATGA AACTGAACAGTGTTTGGCCATGTGTATATTTATATCATGTTTACCAAATCTGTTTAGTGT TCCACATATATGTATATGTATATTTTAATGACTATAATGTAATAAAGTTTATATCATGTT GGTGTATATCATTATAGAAATCATTTTCTAAAGGAGTGAATTCTAAGTTTTAGGGGAAAA AATGCAATTTATTTTCAGACTCCCAAAGTAAGAATTAACATATCATGCTAAGAAAATAGT GACTATTTTGAAGTATGCTACTTCCCTTTCAGAAATATAGAATACACGTTTCTGTTATTA AAGTATTTGATTACTAATTCAAATCATATGGCAATTATAATTCTTCTAAAATGCTATCAT TTGTAACTGTATCCCCTGTATTAAATCTCATTAACCACAGGCAGCTGTTACAGAAAGCTG CATTGTTTCACATTGAGCTGTTACATTAGTTCAGGCTAAATGTTGGGCGCTCCAACCACA TCCAAGAATAAATCTGGAAACACACTGCTGGGATACTGCTGTTAGAGCCCTTCTTGGCCT TGTATTCCCAGAAATGAGCTCCCTTTCCTTAGCTTAGAAGAATGTGATTATATCCAGGAC ATCATGTTCAGAAAACTTAGTTTACTTTCAGCATAGAATGCATTACTGTTGGAATAATTG GCCTCTAGCTCTTAAATGTCTCTGATAACTTATTAATATCTATCTTTATAAAATAGAGTG CAACTACTTTTGTGTAAAAATGTTTGCCTTTAAATTTAGTATTTCATATCAGCACATCGA TATATGTATAAATGTTCCATGTTAATGTGTAAAAGAGTCTGTAATAAATTATTTTTTTCA CGTGTCAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_000857 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000857.1, NP_000848.1 |
| RefSeq Size | 2443 bp |
| RefSeq ORF | 1860 bp |
| Locus ID | 2983 |
| UniProt ID | Q02153 |
| Domains | CYCc |
| Protein Families | Druggable Genome |
| Protein Pathways | Gap junction, Long-term depression, Purine metabolism, Vascular smooth muscle contraction |
| Gene Summary | This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform 2, which lacks an internal segment and is shorter than isoform 1. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Soluble Guanylyl Cyclase a1 and p53 Cytoplasmic Sequestration and Down-Regulation in Prostate Cancer
,Changmeng Cai, Chen-Lin Hsieh, Shuai Gao, Archana Kannan, Meenakshi Bhansali, Kumara Govardhan, Ranendra Dutta, and Lirim Shemshedini,
Mol. Endocrinol., Feb 2012; 26: 292 - 307.
[GUCY1B1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208205 | GUCY1B3 (Myc-DDK-tagged)-Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3) |
CNY 4,608.00 |
|
| RC208205L1 | Lenti ORF clone of Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3), Myc-DDK-tagged |
CNY 7,008.00 |
|
| RC208205L2 | Lenti ORF clone of Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3), mGFP tagged |
CNY 5,890.00 |
|
| RC208205L3 | Lenti ORF clone of Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208205L4 | Lenti ORF clone of Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3), mGFP tagged |
CNY 5,890.00 |
|
| RG208205 | GUCY1B3 (tGFP-tagged) - Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3) |
CNY 6,208.00 |
|
| SC119659 | GUCY1B3 (untagged)-Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3) |
CNY 4,616.00 |
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