STX17 (NM_017919) Human Untagged Clone

CAT#: SC322067

STX17 (untagged)-Human syntaxin 17 (STX17)



  "NM_017919" in other vectors (7)

CNY 3,600.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
STX17 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>NCBI ORF sequence for NM_017919, the custom clone sequence may differ by one or more nucleotides


ATGTCTGAAGATGAAGAAAAAGTGAAATTACGCCGTCTTGAACCAGCTATCCAGAAATTCATTAAGATAG
TAATCCCAACAGACCTGGAAAGGTTAAGAAAGCACCAGATAAATATTGAGAAGTATCAAAGGTGCAGAAT
CTGGGACAAGTTGCATGAAGAGCATATCAATGCAGGACGTACAGTTCAGCAACTCCGATCCAATATCCGA
GAAATTGAGAAACTTTGTTTGAAAGTCCGAAAGGATGACCTAGTACTTCTGAAGAGAATGATAGATCCTG
TTAAAGAAGAAGCATCAGCAGCAACAGCAGAATTTCTCCAACTCCATTTGGAATCTGTAGAAGAACTTAA
GAAGCAATTTAATGATGAAGAAACTTTGCTACAGCCTCCTTTGACCAGATCCATGACTGTTGGTGGAGCA
TTTCATACTACTGAAGCTGAAGCTAGTTCTCAGAGTTTGACTCAGATATATGCCTTACCTGAAATTCCTC
AAGATCAAAATGCTGCAGAATCGTGGGAAACCTTAGAAGCGGACTTAATTGAACTTAGCCAACTGGTCAC
TGACTTCTCTCTCCTAGTGAATTCTCAGCAGGAGAAGATTGACAGCATTGCAGACCATGTCAACAGTGCT
GCTGTGAATGTTGAAGAGGGAACCAAAAACTTAGGGAAGGCTGCAAAATACAAGCTGGCAGCTCTGCCTG
TGGCAGGTGCACTCATCGGGGGAATGGTAGGGGGTCCTATTGGCCTCCTTGCAGGCTTCAAAGTGGCAGG
AATTGCAGCTGCACTTGGTGGTGGGGTGTTGGGCTTCACAGGTGGAAAATTGATACAAAGAAAGAAACAG
AAAATGATGGAGAAGCTCACTTCCAGCTGTCCAGATCTTCCCAGCCAAACTGACAAGAAATGCAGTTAA


Restriction Sites Please inquire     
ACCN NM_017919
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_017919.1, NP_060389.1
RefSeq Size 2678 bp
RefSeq ORF 909 bp
Locus ID 55014
UniProt ID P56962
Domains t_SNARE
Protein Families Druggable Genome, Transmembrane
Protein Pathways SNARE interactions in vesicular transport
Gene Summary SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion (PubMed:23217709, PubMed:25686604, PubMed:28306502). STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane (PubMed:23217709, PubMed:25686604, PubMed:28306502). May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi (PubMed:21545355).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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