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Cytoglobin (CYGB) (NM_134268) Human Untagged Clone
CAT＃: SC321813
CYGB (untagged)-Human cytoglobin (CYGB)
CNY 2,400.00
CNY 2,950.00
| Cited in 9 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HGB; STAP |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_134268.3
CCGCCGCCGAGCAAAGCCGGGCTGGGCTTGGAGCTGCTCATGGAGAAAGTGCCAGGCGAG
ATGGAGATCGAGCGCAGGGAGCGGAGCGAGGAGCTGTCCGAGGCGGAGAGGAAGGCGGTG CAGGCTATGTGGGCCCGGCTCTATGCCAGCTGCGAGGACGTGGGGGTGGCCATCCTGGTG AGGTTCTTTGTGAACTTCCCCTCGGCCAAGCAGTACTTCAGCCAGTTCAAGCACATGGAG GATCCCCTGGAGATGGAGCGGAGCCCCCAGCTGCGGAAGCACGCCTGCCGAGTCATGGGG GCCCTCAACACTGTCGTGGAGAACCTGCATGACCCCGACAAGGTGTCCTCTGTGCTCGCC CTTGTGGGGAAAGCCCACGCCCTCAAGCACAAGGTGGAACCGGTGTACTTCAAGATCCTC TCTGGGGTCATTCTGGAGGTGGTCGCCGAGGAATTTGCCAGTGACTTCCCACCTGAGACG CAGAGAGCCTGGGCCAAGCTGCGTGGCCTCATCTACAGCCACGTGACCGCTGCCTACAAG GAAGTGGGCTGGGTGCAGCAGGTCCCCAACGCCACCACCCCACCGGCCACACTGCCCTCT TCGGGGCCGTAGGACCCCTCCCTCCACCCCCCTCCCTGGCAGCACCTCGAGCAGAAGGCC GAGTTCTGAAGACCCTCCTTGACGCTCCATTTCTGGGTGCCAAGGAAGCTGGAGGAATCC CTGACTCAACTTCCCCGAAGGAGGCCTCTGTGGCGGCCAGGGTCCCCCCCTGGAGCTGCT GGGAGGCGGCGCTGGCTGCCTGGATGCTGACCCCAGCGCGGCGGGCAGAGCGGGGCCCAC TCTTCTTAGCTTTTCTACTCACTGTTAGAGAGAGACCTAGCTGAGCGGCTGGCAGGAAGC GGGACAGGTCTAGGAGTCCCTTAGGGAATAAACCAGCCCCGTTTCTATCAGCCCGGCCAG CATGCAGGTCTCCACATCACCATCTAGAGTATCACGCACACATCTACCATATATACAGAT ACATTCTATATACGAGCTATATATAAATATATATATACATATATATATACACACATACAT ATCTAGAATGTGTATCCGCGGCGCCCAGAAGCCTCGGTTTGGCCCACCTGTGAGTGGGGC AGGGAGGGGTTCCGGTTGTGCAGAGAACAGAGTGTTCTGGCAAAGAGGAAATCCCACAGC AGCGCAGAGGACCTGGGCCTGGAGGGGCAGGGCTGGGGCAACCCGGCTTGGCGGCAAAGC CCAGCCCCTTCTCAGACCAGCTCCCCACATTCCTGAATTCCACTTCCAGGCAGAAAGGAG TGGGCTCCCCCTACTCCCTCAGAGGAACTGACTCACCGGCTGTCCTAGAATGGGCAGGGG CAGAGCGAAGTTCTGGGTGGGATGACCGCACTGGGGGAGGGGCCTCAGTCCAGAAACCTC GACCGCTAGCTCCACCTGCCTTGGCCACCAGGGCAGCCCCAGGGGATCCGGGCTGCTGGG CAGCAGGTCGGCGGGACCACATGCCTGGGTCTCACCCTCAGCTCCGAGGGCCGAGGGCTT TCCCCACCCCACCCTCCTCCTGGCCGGCAGTCGGCCCTGTCTATTCATCTGCGTCAGGCT TGCCAGGGGGGCCCCCCGTGTGTGCCCCTTGGTCACGTGTGTCGTCTTCAAGGATGTTTT GCTGCTGTGGCTCCTGCTGTGTCCCCTCCTGGCCCATCCTCATCCTCATCTTCATCCTCA TCCTCATCTGTGCAACCGCCCGTCCTCCTTTTCTAGTTTCTGATGTTTGTAACCAGACCC AGCTGTGTCATTAAACAGACCCGTTCTTGCTGTAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_134268 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_134268.3, NP_599030.1 |
| RefSeq Size | 1951 bp |
| RefSeq ORF | 573 bp |
| Locus ID | 114757 |
| UniProt ID | Q8WWM9 |
| Domains | globin |
| Gene Summary | This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation. [provided by RefSeq, Jan 2012] |
Citations (9)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Strong modulation of nitrite reductase activity of cytoglobin by disulfide bond oxidation: Implications for nitric oxide homeostasis
,Reeder, BJ;Ukeri, J;,
Nitric Oxide
,PubMed ID 29128400
[CYGB]
|
|
Cell cycle-dependent regulation of cytoglobin by Skp2
,John, R;Atri, Y;Chand, V;Jaiswal, N;Raj, K;Nag, A;,
FEBS Lett.
,PubMed ID 28948618
[CYGB]
|
|
Peroxidase activation of cytoglobin by anionic phospholipids: Mechanisms and consequences
,Tejero, J;Kapralov, AA;Baumgartner, MP;Sparacino-Watkins, CE;Anthonymutu, TS;Vlasova, II;Camacho, CJ;Gladwin, MT;Bayir, H;Kagan, VE;,
Biochim. Biophys. Acta
,PubMed ID 26928591
[CYGB]
|
|
Characterization of zebrafish neuroglobin and cytoglobins 1 and 2: Zebrafish cytoglobins reveal functional divergences with mammalian proteins
,Corti, P;Ieraci, M;Tejero, J;,
Nitric Oxide
,PubMed ID 26721561
[CYGB]
|
|
Effect of the distal histidine on the peroxidatic activity of monomeric cytoglobin
,Beckerson, P;Svistunenko, D;Reeder, B;,
F1000Research
[CYGB]
|
|
Cytoglobin ligand binding regulated by changing haem-coordination in response to intramolecular disulfide bond formation and lipid interaction
,Beckerson, P;Wilson, MT;Svistunenko, DA;Reeder, BJ;,
Biochem. J.
,PubMed ID 25327890
[CYGB]
|
|
DNA damage induced activation of Cygb stabilizes p53 and mediates G1 arrest
,John, R;Chand, V;Chakraborty, S;Jaiswal, N;Nag, A;,
DNA Repair (Amst.)
,PubMed ID 25269893
[CYGB]
|
|
Expression and biological role of cytoglobin in human ovarian cancer
,Chen, H;Zhao, X;Meng, T;,
Tumour Biol. April 2014
,PubMed ID 24737588
[CYGB]
|
|
Cytoglobin has bimodal: tumour suppressor and oncogene functions in lung cancer cell lines
,Urszula Oleksiewicz, Triantafillos Liloglou, Kalliopi-Maria Tasopoulou, Nikoleta Daskoulidou, Julie Bryan, John R. Gosney, John K. Field, and George Xinarianos,
Hum. Mol. Genet., Aug 2013; 22: 3207 - 3217.
,PubMed ID 23591990
[CYGB]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206642 | CYGB (Myc-DDK-tagged)-Human cytoglobin (CYGB) |
CNY 2,400.00 |
|
| RC206642L3 | Lenti ORF clone of Human cytoglobin (CYGB), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206642L4 | Lenti ORF clone of Human cytoglobin (CYGB), mGFP tagged |
CNY 5,890.00 |
|
| RG206642 | CYGB (tGFP-tagged) - Human cytoglobin (CYGB) |
CNY 4,000.00 |
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