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CD247 (NM_000734) Human Untagged Clone
CAT＃: SC321778
CD247 (untagged)-Human CD247 molecule (CD247), transcript variant 2
CNY 1,200.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD3-ZETA; CD3H; CD3Q; CD3Z; IMD25; T3Z; TCRZ |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_000734.2
CGTCCCGGCCACCGCTGCCTCAGCCTCTGCCTCCCAGCCTCTTTCTGAGGGAAAGGACAA
GATGAAGTGGAAGGCGCTTTTCACCGCGGCCATCCTGCAGGCACAGTTGCCGATTACAGA GGCACAGAGCTTTGGCCTGCTGGATCCCAAACTCTGCTACCTGCTGGATGGAATCCTCTT CATCTATGGTGTCATTCTCACTGCCTTGTTCCTGAGAGTGAAGTTCAGCAGGAGCGCAGA CGCCCCCGCGTACCAGCAGGGCCAGAACCAGCTCTATAACGAGCTCAATCTAGGACGAAG AGAGGAGTACGATGTTTTGGACAAGAGACGTGGCCGGGACCCTGAGATGGGGGGAAAGCC GCAGAGAAGGAAGAACCCTCAGGAAGGCCTGTACAATGAACTGCAGAAAGATAAGATGGC GGAGGCCTACAGTGAGATTGGGATGAAAGGCGAGCGCCGGAGGGGCAAGGGGCACGATGG CCTTTACCAGGGTCTCAGTACAGCCACCAAGGACACCTACGACGCCCTTCACATGCAGGC CCTGCCCCCTCGCTAACAGCCAGGGGATTTCACCACTCAAAGGCCAGACCTGCAGACGCC CAGATTATGAGACACAGGATGAAGCATTTACAACCCGGTTCACTCTTCTCAACCACTGAA GTATTCCCCTTTATGTACAGGATGCTTTGGTTATATTTAGCTCCAAACCTTCACACACAG ACTGTTGTCCCTGCACTCTTTAAGGGAGTGTACTCCCAGGGCTTACGGCCCTGGCCTTGG GCCCTCTGGTTTGCCGGTGGTGCAGGTAGACCTGTCTCCTGGCGGTTCCTCGTTCTCCCT GGGAGGCGGGCGCACTGCCTCTCACAGCTGAGTTGTTGAGTCTGTTTTGTAAAGTCCCCA GAGAAAGCGCAGATGCTAGCACATGCCCTAATGTCTGTATCACTCTGTGTCTGAGTGGCT TCACTCCTGCTGTAAATTTGGCTTCTGTTGTCACCTTCACCTCCTTTCAAGGTAACTGTA CTGGGCCATGTTGTGCCTCCCTGGTGAGAGGGCCGGGCAGAGGGGCAGATGGAAAGGAGC CTAGGCCAGGTGCAACCAGGGAGCTGCAGGGGCATGGGAAGGTGGGCGGGCAGGGGAGGG TCAGCCAGGGCCTGCGAGGGCAGCGGGAGCCTCCCTGCCTCAGGCCTCTGTGCCGCACCA TTGAACTGTACCATGTGCTACAGGGGCCAGAAGATGAACAGACTGACCTTGATGAGCTGT GCACAAAGTGGCATAAAAAACATGTGGTTACACAGTGTGAATAAAGTGCTGCGGAGCAAG AGGAGGCCGTTGATTCACTTCACGCTTTCAGCGAATGACAAAATCATCTTTGTGAAGGCC TCGCAGGAAGACCCAACACTTGGGACCTATAACTGCCCAGCGGACAGTGGCAGGACAGGA AAAACCCGTCAATGTACTAGGATACTGCTGCGTCATTACAGGGCACAGGCCATGGATGGA AAACGCTCTCTGCTCTGCTTTTTTTCTACTGTTTTAATTTATACTGGCATGCTAAAGCCT TCCTATTTTGCATAATAAATGCTTCAGTGAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_000734 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000734.2, NP_000725.1 |
| RefSeq Size | 1674 bp |
| RefSeq ORF | 492 bp |
| Locus ID | 919 |
| UniProt ID | P20963 |
| Domains | ITAM |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway |
| Gene Summary | The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) uses an alternate splice site in the mid-coding region, which results in a missing in-frame codon, as compared to variant 1. The encoded isoform (2) is thus missing an internal amino acid, as compared to isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206562 | CD247 (Myc-DDK-tagged)-Human CD247 molecule (CD247), transcript variant 2 |
CNY 1,200.00 |
|
| RC206562L1 | Lenti ORF clone of Human CD247 molecule (CD247), transcript variant 2, Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC206562L2 | Lenti ORF clone of Human CD247 molecule (CD247), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC206562L3 | Lenti ORF clone of Human CD247 molecule (CD247), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206562L4 | Lenti ORF clone of Human CD247 molecule (CD247), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG206562 | CD247 (tGFP-tagged) - Human CD247 molecule (CD247), transcript variant 2 |
CNY 2,800.00 |
