PIAS2 (NM_173206) Human Untagged Clone

CAT#: SC321603

PIAS2 (untagged)-Human protein inhibitor of activated STAT, 2 (PIAS2), transcript variant alpha



  "NM_173206" in other vectors (6)

CNY 4,264.00

CNY 7,220.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
PIAS2 mouse monoclonal antibody,clone OTI5B4
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms ARIP3; DIP; MIZ1; PIASX; SIZ2; ZMIZ4
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_173206.2 GACGGGCCCGGCTGTAGCGGCGGCGGCCGCGGCGTCTTAAGCGGCGCCCAGTGCAGGATG
GTGCTGGAGGCGGCGGCGGCCGTGGTGGCGGCAGCGTCGTTGGCGGCAGCGGGAGTGGGT
GCGGCGGCAGCGGCGGCGGCGCCCGCGGGTGGTATAAAATGGCGGATTTCGAAGAGTTGA
GGAATATGGTTTCTAGTTTTAGGGTTTCTGAACTACAAGTATTACTAGGCTTTGCTGGAC
GGAATAAAAGTGGACGCAAGCATGACCTCCTGATGAGGGCGCTGCATTTATTGAAGAGCG
GCTGCAGCCCTGCGGTTCAGATTAAAATCCGAGAATTGTATAGACGCCGATATCCACGAA
CTCTTGAAGGACTTTCTGATTTATCCACAATCAAATCATCGGTTTTCAGTTTGGATGGTG
GCTCATCACCTGTAGAACCTGACTTGGCCGTGGCTGGAATCCACTCGTTGCCTTCCACTT
CAGTTACACCTCACTCACCATCCTCTCCTGTTGGTTCTGTGCTGCTTCAAGATACTAAGC
CCACATTTGAGATGCAGCAGCCATCTCCCCCAATTCCTCCTGTCCATCCTGATGTGCAGT
TAAAAAATCTGCCCTTTTATGATGTCCTTGATGTTCTCATCAAGCCCACGAGTTTAGTTC
AAAGCAGTATTCAGCGATTTCAAGAGAAGTTTTTTATTTTTGCTTTGACACCTCAACAAG
TTAGAGAGATATGCATATCCAGGGATTTTTTGCCAGGTGGTAGGAGAGATTATACAGTCC
AAGTTCAGTTGAGACTTTGCCTGGCAGAGACAAGTTGCCCTCAAGAAGATAACTATCCAA
ATAGTCTATGTATAAAAGTAAATGGGAAGCTATTTCCTTTGCCTGGCTATGCACCACCGC
CTAAAAATGGGATTGAACAGAAGCGCCCTGGACGCCCCTTGAATATTACATCTTTAGTTA
GGTTATCTTCAGCTGTGCCAAACCAAATTTCCATTTCTTGGGCATCAGAAATTGGGAAGA
ATTACTCTATGTCTGTATATCTTGTACGGCAGCTTACATCAGCCATGTTATTACAGAGAT
TAAAAATGAAAGGTATTAGAAACCCTGATCATTCCAGAGCACTAATTAAAGAAAAACTTA
CTGCAGATCCTGATAGTGAAATTGCTACAACTAGCCTTCGGGTATCCTTGATGTGCCCTT
TAGGAAAAATGAGGCTGACAATCCCATGCCGTGCAGTGACTTGTACACATCTGCAGTGTT
TTGATGCTGCCCTCTATCTACAAATGAATGAGAAAAAGCCCACCTGGATTTGTCCTGTGT
GTGACAAAAAAGCTGCCTATGAAAGTCTAATATTAGATGGGCTTTTTATGGAAATTCTCA
ATGACTGTTCTGATGTAGATGAGATCAAATTCCAAGAAGATGGTTCTTGGTGTCCAATGA
GACCGAAGAAAGAAGCTATGAAAGTATCCAGCCAACCGTGTACAAAAATAGAAAGTTCAA
GCGTCCTCAGTAAGCCTTGTTCAGTGACTGTAGCCAGTGAGGCAAGCAAGAAGAAAGTAG
ATGTTATTGATCTTACAATAGAAAGCTCTTCTGACGAAGAGGAAGACCCTCCTGCCAAAA
GGAAATGCATCTTTATGTCAGAAACACAAAGCAGCCCAACCAAAGGGGTTCTCATGTATC
AGCCATCTTCTGTAAGGGTGCCCAGTGTGACTTCGGTTGATCCTGCTGCTATTCCGCCTT
CATTAACAGACTACTCAGTACCATTCCACCATACGCCAATATCAAGCATGTCATCAGATT
TGCCAGGAGAACAAAGAAGAAATGATATTAATAATGAACTGAAGCTTGGAACATCTTCTG
ATACTGTGCAACAGTGAATACAAAATAAAACAAATAATTCGAAAAAAAAAAAAAAAAAAA
AAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_173206
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_173206.2, NP_775298.1
RefSeq Size 1919 bp
RefSeq ORF 1719 bp
Locus ID 9063
UniProt ID O75928
Protein Families Stem cell - Pluripotency, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors
Protein Pathways Jak-STAT signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis
Gene Summary This gene encodes a member of the protein inhibitor of activated STAT family, which function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2017]
Transcript Variant: This variant (alpha) utilizes an alternate 3' coding exon, compared to variant beta, resulting in a shorter isoform (alpha) that has a unique C-terminus compared to isoform beta. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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