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CCR1 (NM_001295) Human Untagged Clone
CAT＃: SC321474
CCR1 (untagged)-Human chemokine (C-C motif) receptor 1 (CCR1)
CNY 3,656.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD191; CKR-1; CKR1; CMKBR1; HM145; MIP1aR; SCYAR1 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_001295.2
AAAGCCCCAGAAACAAAGACTTCACGGACAAAGTCCCTTGGAACCAGAGAGAAGCCGGGA
TGGAAACTCCAAACACCACAGAGGACTATGACACGACCACAGAGTTTGACTATGGGGATG CAACTCCGTGCCAGAAGGTGAACGAGAGGGCCTTTGGGGCCCAACTGCTGCCCCCTCTGT ACTCCTTGGTATTTGTCATTGGCCTGGTTGGAAACATCCTGGTGGTCCTGGTCCTTGTGC AATACAAGAGGCTAAAAAACATGACCAGCATCTACCTCCTGAACCTGGCCATTTCTGACC TGCTCTTCCTGTTCACGCTTCCCTTCTGGATCGACTACAAGTTGAAGGATGACTGGGTTT TTGGTGATGCCATGTGTAAGATCCTCTCTGGGTTTTATTACACAGGCTTGTACAGCGAGA TCTTTTTCATCATCCTGCTGACGATTGACAGGTACCTGGCCATCGTCCACGCCGTGTTTG CCTTGCGGGCACGGACCGTCACTTTTGGTGTCATCACCAGCATCATCATTTGGGCCCTGG CCATCTTGGCTTCCATGCCAGGCTTATACTTTTCCAAGACCCAATGGGAATTCACTCACC ACACCTGCAGCCTTCACTTTCCTCACGAAAGCCTACGAGAGTGGAAGCTGTTTCAGGCTC TGAAACTGAACCTCTTTGGGCTGGTATTGCCTTTGTTGGTCATGATCATCTGCTACACAG GGATTATAAAGATTCTGCTAAGACGACCAAATGAGAAGAAATCCAAAGCTGTCCGTTTGA TTTTTGTCATCATGATCATCTTTTTTCTCTTTTGGACCCCCTACAATTTGACTATACTTA TTTCTGTTTTCCAAGACTTCCTGTTCACCCATGAGTGTGAGCAGAGCAGACATTTGGACC TGGCTGTGCAAGTGACGGAGGTGATCGCCTACACGCACTGCTGTGTCAACCCAGTGATCT ACGCCTTCGTTGGTGAGAGGTTCCGGAAGTACCTGCGGCAGTTGTTCCACAGGCGTGTGG CTGTGCACCTGGTTAAATGGCTCCCCTTCCTCTCCGTGGACAGGCTGGAGAGGGTCAGCT CCACATCTCCCTCCACAGGGGAGCATGAACTCTCTGCTGGGTTCTGACTCAGACCATAGG AGGCCAACCCAAAATAAGCAGGCGTGACCTGCCAGGCACACTGAGCCAGCAGCCTGGCTC TCCCAGCCAGGTTCTGACTCTTGGCACAGCATGGAGTCACAGCCACTTGGGATAGAGAGG GAATGTAATGGTGGCCTGGGGCTTCTGAGGCTTCTGGGGCTTCAGTCTTTTCCATGAACT TCTCCCCTGGTAGAAAGAAGATGAATGAGCAAAACCAAATATTCCAGAGACTGGGACTAA GTGTACCAGAGAAGGGCTTGGACTCAAGCAAGATTTCAGATTTGTGACCATTAGCATTTG TCAACAAAGTCACCCACTTCCCACTATTGCTTGCACAAACCAATTAAACCCAGTAGTGGT GACTGTGGGCTCCATTCAAAGTGAGCTCCTAAGCCATGGGAGACACTGATGTATGAGGAA TTTCTGTTCTTCCATCACCTCCCCCCCCCCGCCACCCTCCCACTGCCAAAGAACTTGGAA ATAGTGATTTCCACAGTGACTCCACTCTGAGTCCCAGAGCCAATCAGTAGCCAGCATCTG CCTCCCCTTCACTCCCACCGCAGGATTTGGGCTCTTGGAATCCTGGGGAACATAGAACTC ATGACGGAAGAGTTGAGACCTAACGAGAAATAGAAATGGGGAACTACTGCTGGCAGTGGA ACTAAGAAAGCCCTTAGGAAGAATTTTTATATCCACTAAAATCAAACAATTCAGGGAGTG GGCTAAGCACGGGCCATATGAATAACATGGTGTGCTTCTTAAAATAGCCATAAAGGGGAG GGACTCATCATTTCCATTTACCCTTCTTTTCTGACTATTTTTCAGAATCTCTCTTCTTTT CAAGTTGGGTGATATGTTGGTAGATTCTAATGGCTTTATTGCAGCGATTAATAACAGGCA AAAGGAAGCAGGGTTGGTTTCCCTTCTTTTTGTTCTTCATCTAAGCCTTCTGGTTTTATG GGTCAGAGTTCCGACTGCCATCTTGGACTTGTCAGCAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001295 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001295.2, NP_001286.1 |
| RefSeq Size | 2690 bp |
| RefSeq ORF | 1068 bp |
| Locus ID | 1230 |
| UniProt ID | P32246 |
| Domains | 7tm_1 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
| Gene Summary | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The Lupane-type Triterpene 30-Oxo-calenduladiol Is a CCR5 Antagonist with Anti-HIV-1 and Anti-chemotactic Activities
,Jonathan Barroso-González, Nabil El Jaber-Vazdekis, Laura García-Expósito, José-David Machado, Rafael Zárate, Ángel G. Ravelo, Ana Estévez-Braun, and Agustín Valenzuela-Fernández,
J. Biol. Chem., Jun 2009; 284: 16609 - 16620.
[CCR1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208605 | CCR1 (Myc-DDK-tagged)-Human chemokine (C-C motif) receptor 1 (CCR1) |
CNY 3,656.00 |
|
| RC208605L1 | Lenti ORF clone of Human chemokine (C-C motif) receptor 1 (CCR1), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC208605L2 | Lenti ORF clone of Human chemokine (C-C motif) receptor 1 (CCR1), mGFP tagged |
CNY 5,890.00 |
|
| RC208605L3 | Lenti ORF clone of Human chemokine (C-C motif) receptor 1 (CCR1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208605L4 | Lenti ORF clone of Human chemokine (C-C motif) receptor 1 (CCR1), mGFP tagged |
CNY 6,056.00 |
|
| RG208605 | CCR1 (tGFP-tagged) - Human chemokine (C-C motif) receptor 1 (CCR1) |
CNY 5,256.00 |
