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Oct-1 (POU2F1) (NM_002697) Human Untagged Clone
CAT＃: SC321473
POU2F1 (untagged)-Human POU class 2 homeobox 1 (POU2F1), transcript variant 1
CNY 8,176.00
| Cited in 4 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | oct-1B; OCT1; OTF1 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_002697 edited
CGGAGGAGCAGCGAGTCAAGATGAGAGTTCAGCCGCGGCGGCAGCAGCAGCAGACTGGAA AAGTAAGAAGAGCTTTCCTGCCTTTTTAATTACCAAACTACTCTCAGTTTTCAATGAATC AGTTCAAAGAAAGAATGCAGTCTTTCTATACCTGACTCAAGAATGAACAATCCGTCAGAA ACCAGTAAACCATCTATGGAGAGTGGAGATGGCAACACAGGCACACAAACCAATGGTCTG GACTTTCAGAAGCAGCCTGTGCCTGTAGGAGGAGCAATCTCAACAGCCCAGGCGCAGGCT TTCCTTGGACATCTCCATCAGGTCCAACTCGCTGGAACAAGTTTACAGGCTGCTGCTCAG TCTTTAAATGTACAGTCTAAATCTAATGAAGAATCGGGGGATTCGCAGCAGCCAAGCCAG CCTTCCCAGCAGCCTTCAGTGCAGGCAGCCATTCCCCAGACCCAGCTTATGCTAGCTGGA GGACAGATAACTGGGCTTACTTTGACGCCTGCCCAGCAACAGTTACTACTCCAGCAGGCA CAGGCACAGGCACAGCTGCTGGCTGCTGCAGTGCAGCAGCACTCCGCCAGCCAGCAGCAC AGTGCTGCTGGAGCCACCATCTCCGCCTCTGCTGCCACGCCCATGACGCAGATCCCCCTG TCTCAGCCCATACAGATCGCACAGGATCTTCAACAACTGCAACAGCTTCAACAGCAGAAT CTCAACCTGCAACAGTTTGTGTTGGTGCATCCAACCACCAATTTGCAGCCAGCGCAGTTT ATCATCTCACAGACGCCCCAGGGCCAGCAGGGTCTCCTGCAAGCGCAAAATCTTCTAACG CAACTACCTCAGCAAAGCCAAGCCAACCTCCTACAGTCGCAGCCAAGCATCACCCTCACC TCCCAGCCAGCAACCCCAACACGCACAATAGCAGCAACCCCAATTCAGACACTTCCACAG AGCCAGTCAACACCAAAGCGAATTGATACTCCCAGCTTGGAGGAGCCCAGTGACCTTGAG GAGCTTGAGCAGTTTGCCAAGACCTTCAAACAAAGACGAATCAAACTTGGATTCACTCAG GGTGATGTTGGGCTCGCTATGGGGAAACTATATGGAAATGACTTCAGCCAAACTACCATC TCTCGATTTGAAGCCTTGAACCTCAGCTTTAAGAACATGTGCAAGTTGAAGCCACTTTTA GAGAAGTGGCTAAATGATGCAGAGAACCTCTCATCTGATTCGTCCCTCTCCAGCCCAAGT GCCCTGAATTCTCCAGGAATTGAGGGCTTGAGCCGTAGGAGGAAGAAACGCACCAGCATA GAGACCAACATCCGTGTGGCCTTAGAGAAGAGTTTCTTGGAGAATCAAAAGCCTACCTCG GAAGAGATCACTATGATTGCTGATCAGCTCAATATGGAAAAAGAGGTGATTCGTGTTTGG TTCTGTAACCGCCGCCAGAAAGAAAAAAGAATCAACCCACCAAGCAGTGGTGGGACCAGC AGCTCACCTATTAAAGCAATTTTCCCCAGCCCAACTTCACTGGTGGCGACCACACCAAGC CTTGTGACTAGCAGTGCAGCAACTACCCTCACAGTCAGCCCTGTCCTCCCTCTGACCAGT GCTGCTGTGACGAATCTTTCAGTTACAGGCACTTCAGACACCACCTCCAACAACACAGCA ACCGTGATTTCCACAGCGCCTCCAGCTTCCTCAGCAGTCACGTCCCCCTCTCTGAGTCCC TCCCCTTCTGCCTCAGCCTCCACCTCCGAGGCATCCAGTGCCAGTGAGACCAGCACAACA CAGACCACCTCCACTCCTTTGTCCTCCCCTCTTGGGACCAGCCAGGTGATGGTGACAGCA TCAGGTTTGCAAACAGCAGCAGCTGCTGCCCTTCAAGGAGCTGCACAGTTGCCAGCAAAT GCCAGTCTTGCTGCCATGGCAGCTGCTGCAGGACTAAACCCAAGCCTGATGGCACCCTCA CAGTTTGCGGCTGGAGGTGCCTTACTCAGTCTGAATCCAGGGACCCTGAGCGGTGCTCTC AGCCCAGCTCTAATGAGCAACAGTACACTGGCAACTATTCAAGCTCTTGCTTCTGGTGGC TCTCTTCCAATAACATCACTTGATGCAACTGGGAACCTGGTATTTGCCAATGCGGGAGGA GCCCCCAACATCGTGACTGCCCCTCTGTTCCTGAACCCTCAGAACCTCTCTCTGCTCACC AGCAACCCTGTTAGCTTGGTCTCTGCCGCCGCAGCATCTGCAGGGAACTCTGCACCTGTA GCCAGCCTTCACGCCACCTCCACCTCTGCTGAGTCCATCCAGAACTCTCTCTTCACAGTG GCCTCTGCCAGCGGGGCTGCGTCCACCACCACCACCGCCTCCAAGGCACAGTGAGCTGGG CAGAGCTGGGCTGCCAGAAGCCTTTTTCACTCTGCAGTGTGATTGGACTGCCAGCCAGGT TAATAAACTGAAAAATGTGATTGGCTTCCTCTCGCCGTGTTGTGAGGGCAAAGGAGAGAA GGGAGAAAAAAAAAAAAAAACCACACACACCCATACACACATACCAGAAAAAGAAAGAAA GGATGGAGACGGAACATTTGCCTAATTTTGTAATAAAACACTGTCTTTTCAGGATTGCTT CATGGATTGGAGAACTTTCTAACCAAAAATTAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_002697 |
| Insert Size | 2500 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_002697.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002697.2, NP_002688.2 |
| RefSeq Size | 2689 bp |
| RefSeq ORF | 2232 bp |
| Locus ID | 5451 |
| UniProt ID | P14859 |
| Domains | POU, homeobox |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010] Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (4)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Tumor cell-secreted angiogenin induces angiogenic activity of endothelial cells by suppressing miR-542-3p
,He, T;Qi, F;Jia, L;Wang, S;Wang, C;Song, N;Fu, Y;Li, L;Luo, Y;,
Cancer Lett.
,PubMed ID 26272182
[POU2F1]
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Distinct Interaction of Nilotinib and Imatinib with P-Glycoprotein in Intracellular Accumulation and Cytotoxicity in CML Cell Line K562 Cells
,Yamakawa, Y;Hamada, A;Uchida, T;Sato, D;Yuki, M;Hayashi, M;Kawaguchi, T;Saito, H;,
Biol. Pharm. Bull.
,PubMed ID 25087954
[POU2F1]
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Identification of functional amino Acid residues involved in polyamine and agmatine transport by human organic cation transporter 2
,Higashi, K;Imamura, M;Fudo, S;Uemura, T;Saiki, R;Hoshino, T;Toida, T;Kashiwagi, K;Igarashi, K;,
PLoS ONE July 2014
,PubMed ID 25019617
[POU2F1]
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The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina
,Sacha Reichman, Ravi Kiran Reddy Kalathur, Sophie Lambard, Najate Aït-Ali, Yanjiang Yang, Aurélie Lardenois, Raymond Ripp, Olivier Poch, Donald J. Zack, José-Alain Sahel, and Thierry Léveillard,
Hum. Mol. Genet., Jan 2010; 19: 250 - 261
[POU2F1]
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