United States
Germany
Japan
United Kingdom
China
PP2A-alpha (PPP2CA) (NM_002715) Human Untagged Clone
CAT＃: SC321401
PPP2CA (untagged)-Human protein phosphatase 2, catalytic subunit, alpha isozyme (PPP2CA)
CNY 2,400.00
CNY 2,950.00
| Cited in 4 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | NEDLBA; PP2Ac; PP2CA; PP2Calpha; RP-C |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_002715.2
CTCTGGAGCCTCAGCGAGCGGAGGAGGAGGCGCAGCGGCCGACGGCCGAGTACTGCGGTG
AGAGCCAGCGGGCCAGCGCCAGCCTCAACAGCCGCCAGAAGTACACGAGGAACCGGCGGC GGCGTGTGCGTGTAGGCCCGTGTGCGGGCGGCGGCGCGGGAGCAGCGCGGAGCGGCAGCC GGCTGGGGCGGGTGGCATCATGGACGAGAAGGTGTTCACCAAGGAGCTGGACCAGTGGAT CGAGCAGCTGAACGAGTGCAAGCAGCTGTCCGAGTCCCAGGTCAAGAGCCTCTGCGAGAA GGCTAAAGAAATCCTGACAAAAGAATCCAACGTGCAAGAGGTTCGATGTCCAGTTACTGT CTGTGGAGATGTGCATGGGCAATTTCATGATCTCATGGAACTGTTTAGAATTGGTGGCAA ATCACCAGATACAAATTACTTGTTTATGGGAGATTATGTTGACAGAGGATATTATTCAGT TGAAACAGTTACACTGCTTGTAGCTCTTAAGGTTCGTTACCGTGAACGCATCACCATTCT TCGAGGGAATCATGAGAGCAGACAGATCACACAAGTTTATGGTTTCTATGATGAATGTTT AAGAAAATATGGAAATGCAAATGTTTGGAAATATTTTACAGATCTTTTTGACTATCTTCC TCTCACTGCCTTGGTGGATGGGCAGATCTTCTGTCTACATGGTGGTCTCTCGCCATCTAT AGATACACTGGATCATATCAGAGCACTTGATCGCCTACAAGAAGTTCCCCATGAGGGTCC AATGTGTGACTTGCTGTGGTCAGATCCAGATGACCGTGGTGGTTGGGGTATATCTCCTCG AGGAGCTGGTTACACCTTTGGGCAAGATATTTCTGAGACATTTAATCATGCCAATGGCCT CACGTTGGTGTCTAGAGCTCACCAGCTAGTGATGGAGGGATATAACTGGTGCCATGACCG GAATGTAGTAACGATTTTCAGTGCTCCAAACTATTGTTATCGTTGTGGTAACCAAGCTGC AATCATGGAACTTGACGATACTCTAAAATACTCTTTCTTGCAGTTTGACCCAGCACCTCG TAGAGGCGAGCCACATGTTACTCGTCGTACCCCAGACTACTTCCTGTAATGAAATTTTAA ACTTGTACAGTATTGCCATGAACCATATATCGACCTAATGGAAATGGGAAGAGCAACAGT AACTCCAAAGTGTCAGAAAATAGTTAACATTCAAAAAACTTGTTTTCACATGGACCAAAA GATGTGCCATATAAAAATACAAAGCCTCTTGTCATCAACAGCCGTGACCACTTTAGAATG AACCAGTTCATTGCATGCTGAAGCGACATTGTTGGTCAAGAAACCAGTTTCTGGCATAGC GCTATTTGTAGTTACTTTTGCTTTCTCTGAGAGACTGCAGATAATAAGATGTAAACATTA ACACCTCGTGAATACAATTTAACTTCCATTTAGCTATAGCTTTACTCAGCATGACTGTAG ATAAGGATAGCAGCAAACAATCATTGGAGCTTAATGAACATTTTTAAAAATAATTACCAA GGCCTCCCTTCTACTTGTGAGTTTTGAAATTGTTCTTTTTATTTTCAGGGATACCGTTTA ATTTAATTATATGATTTGTCTGCACTCAGTTTATTCCCTACTCAAATCTCAGCCCCATGT TGTTCTTTGTTATTGTCAGAACCTGGTGAGTTGTTTTGAACAGAACTGTTTTTTCCCCTT CCTGTAAGACGATGTGACTGCACAAGAGCACTGCAGTGTTTTTCATAATAAACTTGTGAA CTAAGAACTGAGAAGGTCAAATTTTAATTGTATCAATGGGCAAGACTGGTGCTGTTTATT AAAAAAGTTAAATCAATTGAGTAAATTTTAGAATTTGTAGACTTGTAGGTAAAATAAAAA TCAAGGGCACTACATAACCTCTCTGGTAACTCCTTGACATTCTTCAGATTAACTTCAGGA TTTATTTGTATTTCACATATTACAATTTGTCACATTGTTGGTGTGCACTTTGTGGGTTCT TCCTGCATATTAACTTGTTTGTAAGAAAGGAAATCTGTGCTGCTTCAGTAAGACTTAATT GTAAAACCATATAACTTGAGATTTAAGTCTTTGGGTTTTGTTTTAATAAAACAGCATGTT TTCAGGTAGAGCTTAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_002715 |
| Insert Size | 930 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002715.2, NP_002706.1 |
| RefSeq Size | 2643 bp |
| RefSeq ORF | 930 bp |
| Locus ID | 5515 |
| UniProt ID | P67775 |
| Domains | Metallophos, PP2Ac |
| Protein Families | Druggable Genome, Phosphatase, Transcription Factors |
| Protein Pathways | Long-term depression, Oocyte meiosis, TGF-beta signaling pathway, Tight junction, Wnt signaling pathway |
| Gene Summary | This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (4)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
CD25 and protein phosphatase 2A cooperate to enhance IL-2R signaling in human regulatory T cells
,null,
Journal of immunology (Baltimore, Md. : 1950)
,PubMed ID 31085588
[PPP2CA]
|
|
Involvement of vacuolar H(+) -ATPase in killing of human melanoma cells by the sphingosine kinase analogue FTY720
,Tay, KH;Liu, X;Chi, M;Jin, L;Jiang, CC;Guo, ST;Verrills, NM;Tseng, HY;Zhang, XD;,
Pigment Cell Melanoma Res
,PubMed ID 25358761
[PPP2CA]
|
|
Suppression of PP2A is critical for protection of melanoma cells upon endoplasmic reticulum stress
,K H Tay, L Jin, H-Y Tseng, C C Jiang, Y Ye, R F Thorne, T Liu, S T Guo, N M Verrills, P Hersey & X D Zhang,
Cell Death and Disease 3, e337 doi:10.1038/cddis.2012.79
[PPP2CA]
|
|
Suppression of PP2A is critical for protection of melanoma cells upon endoplasmic reticulum stress
,null,
Cell Death & Disease
,PubMed ID 22739989
[PPP2CA]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201334 | PPP2CA (Myc-DDK-tagged)-Human protein phosphatase 2, catalytic subunit, alpha isozyme (PPP2CA) |
CNY 2,400.00 |
|
| RC201334L1 | Lenti ORF clone of Human protein phosphatase 2, catalytic subunit, alpha isozyme (PPP2CA), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC201334L2 | Lenti ORF clone of Human protein phosphatase 2, catalytic subunit, alpha isozyme (PPP2CA), mGFP tagged |
CNY 5,890.00 |
|
| RC201334L3 | Lenti ORF clone of Human protein phosphatase 2, catalytic subunit, alpha isozyme (PPP2CA), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC201334L4 | Lenti ORF clone of Human protein phosphatase 2, catalytic subunit, alpha isozyme (PPP2CA), mGFP tagged |
CNY 4,800.00 |
|
| RG201334 | PPP2CA (tGFP-tagged) - Human protein phosphatase 2, catalytic subunit, alpha isozyme (PPP2CA) |
CNY 4,000.00 |
其它PP2A-alpha产品
