United States
Germany
Japan
United Kingdom
China
PNRC2 (NM_017761) Human Untagged Clone
CAT＃: SC321359
PNRC2 (untagged)-Human proline-rich nuclear receptor coactivator 2 (PNRC2)
CNY 1,200.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_017761.2
AGAAGGAGAAGGTCGGGTTGTAGAAGCTGGGGTGGCCGGCAGCTCGCTCATCGGTGTTCG
TGGGCTTTGTCGGTCCGTGCCTCGTCTCTCCCTGGAAAGGGAGGGAGGCTTCGACGTCGA GAGGGAGCCGCTGCCGCGTTAGTTCCGAGCTTGAAGTCACTAGGACTTCTCTCAAACTTG TGTGCTGAGGAGACTCAGATGTTGGCCTCAGCTCCTAGGCTGAACTCAGCAGATCGGCCC ATGAAAACTTCTGTATTGAGACAAAGGAAGGGATCTGTCAGAAAGCAACACTTGTTATCT TGGGCTTGGCAGCAAGGAAGAGGACAGGTAGTGGAGATCCTGCAATCTGAAAAGCAGACT GAAAGGTGACAAAGAAGCTGAAGATGGGTGGTGGAGAGAGGTATAACATTCCAGCCCCTC AATCTAGAAATGTTAGTAAGAACCAACAACAGCTTAACAGACAGAAGACCAAGGAACAGA ATTCCCAGATGAAGATTGTTCATAAGAAAAAAGAAAGAGGACATGGTTATAACTCATCAG CAGCTGCCTGGCAGGCCATGCAAAATGGGGGGAAGAACAAAAATTTTCCAAATAATCAAA GTTGGAATTCTAGCTTATCAGGTCCCAGGTTACTTTTTAAATCTCAAGCTAATCAGAACT ATGCTGGTGCCAAATTTAGTGAGCCGCCATCACCAAGTGTTCTTCCCAAACCACCAAGCC ACTGGGTCCCTGTTTCCTTTAATCCTTCAGATAAGGAAATAATGACATTTCAACTTAAAA CCTTACTTAAAGTACAGGTATAAAATAAGACAAATGTTTAAATTTAGTTATGTTCACGGA TAGTTGTCAATTGGTCTGAAACAAATTCGCTAGGGAATCTATTTGTGTAGAACTAATTAA TGTAAAAAAAACAGACCATCTCGTGTTGTGTGCACTGTGATATAATGGTAGTATCAGTGC AACTTTAATGATTGTACTTGATATTAAGTGTTCTCAACTGAGTAACTTTTAAGTGGAAAC CAAGTTTAGATTTGGGGAGTGGTAAAGGAATCAGCTTTTTCTATTGTTAGGGGAAGACAG TAATTTATCATTCATGGACCAGTAGATTGTTGAAAGTTGGTGAATCGGATTATAAGCTTC TAGCTAACACAAGGATTCAGAATTAGGTAAACATCTGAAGGTTTAGTATATTAGAAACAC CCAAACCAGTAATATGCTAACCTGATGCACTGCTGAAAGAAAATGTGAATTTTTCGTAAT AATTGCATTTTAGTGAATTGTACAGTGGGTGGAAAGGGCATTTGGAGCTCATTAGAATGA GACATAGTACACCCCAATGGCCCTGTTTATTAAATGTAGTGGATTAAGTGTCTGTCAACA AATACACCAAAACCATTTTTTATAGAAACAGTATTTAATGGTCACTCAATAGCTTTCAAA ATACATTTTTGTATTACAGCACTGCACAAGCTATTCTAATAGTGCTCTCGCCTCATCATT CCTGCAAAGCTTGCTTTGGGGAGTTGGATAATGTGAAAATTTTAAGTACCTAGGGGAGAA AGAGCCATGTAAATATCTGTAATAAACTTGTAGCATATGTAAAGTTTTCTTGGCCTTTAT CTTACAAAAATGGAGTATTTTAGTATGAATTTGCTGAATGTAAGACCGTGGACTGTTTTT TATAATATGGCCTAATTTTAAAGGTCCAAAATAACTTGTTTTTAAAGTTTGCCCTTGTGC TAAAGTGCCAGTGTATGTATGTTATACTTGATTTGGTTGTAAACTATATTTCAAAGTAAA CCCTAGTGTAATAAGTTTTATAACTAAAAAGGTTTAAGCTGCTAAAACTATTTTTAAGAG ATGTGAAATGCAGTATGGGACTATCTTTTTTTCCTCCTCTAAGCCCAAAGATTAACTAGA GTCCCTCCAACCTTATAGATTGTTGGCTTTCACAATCTTATAACCTAGGATACAGGTAGT TTCGAGTATGGTGCCAGTGATGTTTTGTTTTTGTTTGGTCAAGGGGTAGGTGCAACCCAA TGGACCACTTATGCAAAAGATGTAAACTCTTGCATAATACATTGATAACATGTTTTGCCA ACTTTAAATGCTTAAACATAAGCGAAACCAGTAGCAAGTATGTGGGTCAGCTTAAAAATT TTGATTGTTAATGCCCTATTTTCTAATTTGGCACCTCTTGATGCCTAAGCAGGTAAGCAG ATGCCTAAGCTGTATTTCTCCAAATAAATCAAGATGAAGTACTGCCCAAGTTAAATATTG ATAGCCTAAAGACAAGTTTATGTAGTACTTAATGTACATGATATGAATGTGAAGCATAAA ATTAAATAAAATTTTTCCCCATTAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_017761 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_017761.2, NP_060231.1 |
| RefSeq Size | 2382 bp |
| RefSeq ORF | 420 bp |
| Locus ID | 55629 |
| UniProt ID | Q9NPJ4 |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery (PubMed:19150429). May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs (PubMed:19150429). Required for UPF1/RENT1 localization to the P-body (PubMed:19150429). Plays a role in glucocorticoid receptor-mediated mRNA degradation by interacting with the glucocorticoid receptor NR3C1 in a ligand-dependent manner when it is bound to the 5' UTR of target mRNAs and recruiting the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay (PubMed:25775514). Also acts as a nuclear receptor coactivator (PubMed:11574675). May play a role in controlling the energy balance between energy storage and energy expenditure (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200098 | PNRC2 (Myc-DDK-tagged)-Human proline-rich nuclear receptor coactivator 2 (PNRC2) |
CNY 1,200.00 |
|
| RC200098L3 | Lenti ORF clone of Human proline-rich nuclear receptor coactivator 2 (PNRC2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200098L4 | Lenti ORF clone of Human proline-rich nuclear receptor coactivator 2 (PNRC2), mGFP tagged |
CNY 5,890.00 |
|
| RG200098 | PNRC2 (tGFP-tagged) - Human proline-rich nuclear receptor coactivator 2 (PNRC2) |
CNY 2,800.00 |
