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POT1 (NM_001042594) Human Untagged Clone
CAT＃: SC321304
POT1 (untagged)-Human protection of telomeres 1 homolog (S. pombe) (POT1), transcript variant 4
CNY 3,752.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CMM10; GLM9; HPOT1 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_001042594.1
CTCAAATCAACTGTTTATGTTTATGTCAAATCTTTAAGAGATTTTTCTACAGAATCAATG
TCTTTGGTTCCAGCAACAAATTATATATATACACCCCTGAATCAACTTAAGGGTGGTACA ATTGTCAATGTCTATGGTGTTGTGAAGTTCTTTAAGCCCCCATATCTAAGCAAAGGAACT GATTATTGCTCAGTTGTAACTATTGTGGACCAGACAAATGTAAAACTAACTTGCCTGCTC TTTAGTGGAAACTATGAAGCCCTTCCAATAATTTATAAAAATGGAGATATTGTTCGCTTT CACAGGCTGAAGATTCAAGTATATAAAAAGGAGACTCAGGGTATCACCAGCTCTGGCTTT GCATCTTTGACGTTTGAGGGAACTTTGGGAGCCCCTATCATACCTCGCACTTCAAGCAAG TATTTTAACTTCACTACTGAGGACCACAAAATGGTAGAAGCCTTACGTGTTTGGGCATCT ACTCATATGTCACCGTCTTGGACATTACTAAAATTGTGTGATGTTCAGCCAATGCAGTAT TTTGACCTGACTTGTCAGCTCTTGGGCAAAGCAGAAGTGGACGGAGCATCATTTCTTCTA AAGGTATGGGATGGCACCAGGACACCATTTCCATCTTGGAGAGTCTTAATACAAGACCTT GTTCTTGAAGGTGATTTAAGTCACATCCATCGGCTACAAAATCTGACAATAGACATTTTA GTCTACGATAACCATGTTCATGTGGCAAGATCTCTGAAGGTTGGAAGCTTTCTTAGAATC TATAGCCTTCATACCAAACTTCAATCAATGAATTCAGAGAATCAGACAATGTTAAGTTTA GAGTTTCATCTTCATGGAGGTACCAGTTACGGTCGGGGAATCAGGGTCTTGCCAGAAAGT AACTCTGATGTGGATCAACTGAAAAAGGATTTAGAATCTGCAAATTTGACAGCCAATCAG CATTCAGATGTTATCTGTCAATCAGAACCTGACGACAGCTTTCCAAGCTCTGGATCAGTA TCATTATACGAGGTAGAAAGATGTCAACAGCTATCTGCTACAATACTTACAGATCATCAG TATTTGGAGAGGACACCACTATGTGCCATTTTGAAACAAAAAGCTCCTCAACAATACCGC ATCCGAGCAAAATTGAGGTCATATAAGCCCAGAAGACTATTTCAGTCTGTTAAACTTCAT TGCCCTAAATGTCATTTGCTGCAAGAAGTTCCACATGAGGGCGATTTGGATATAATTTTT CAGGATGGTGCAACTAAAACCCCAGATGTCAAGCTACAAAATACATCATTATATGATTCA AAAATCTGGACCACTAAAAATCAAAAAGGACGAAAAGTAGCAGTTCATTTTGTGAAAAAT AATGGTATTCTCCCGCTTTCAAATGAATGTCTACTTTTGATAGAAGGAGGTACACTCAGT GAAATTTGCAAACTCTCGAACAAGTTTAATAGTGTAATTCCTGTGAGATCTGGCCACGAA GACCTGGAACTTTTGGACCTTTCAGCACCATTTCTTATACAAGGAACAATACATCACTAT GGATGTAAACAGTGTTCTAGTTTGAGATCCATACAAAATCTAAATTCCCTGGTTGATAAA ACATCGTGGATTCCTTCTTCTGTGGCAGAAGCACTGGGTATTGTACCCCTCCAATATGTG TTTGTTATGACCTTTACACTTGATGATGGAACAGGAGTACTAGAAGCCTATCTCATGGAT TCTGACAAATTCTTCCAGATTCCAGCATCAGAAGTTCTGATGGATGATGACCTTCAGAAA AGTGTGGATATGATCATGGATATGTTTTGTCCTCCAGGAATAAAAATTGATGCATATCCG TGGTTGGAATGCTTCATCAAGTCATACAATGTCACAAATGGAACAGATAATCAAATTTGC TATCAGATTTTTGACACCACAGTTGCAGAAGATGTAATCTAATATTGCCATCCAATTTAG CATACATAAAATGTTGCCACTCAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001042594 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001042594.1, NP_001036059.1 |
| RefSeq Size | 3964 bp |
| RefSeq ORF | 1512 bp |
| Locus ID | 25913 |
| UniProt ID | Q9NUX5 |
| Gene Summary | This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (4) lacks an alternate in-frame exon in the 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (5, also known as POT1-55) has a shorter N-terminus, compared to isoform 1. There are currently no publicly available full-length transcripts representing this variant, but it is supported by data in PMIDs 12391173 and 15973431. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202396 | POT1 (Myc-DDK-tagged)-Human protection of telomeres 1 homolog (S. pombe) (POT1), transcript variant 4 |
CNY 6,370.00 |
|
| RC202396L3 | Lenti-ORF clone of POT1 (Myc-DDK-tagged)-Human protection of telomeres 1 homolog (S. pombe) (POT1), transcript variant 4 |
CNY 8,270.00 |
|
| RC202396L4 | Lenti-ORF clone of POT1 (mGFP-tagged)-Human protection of telomeres 1 homolog (S. pombe) (POT1), transcript variant 4 |
CNY 8,270.00 |
|
| RG202396 | POT1 (tGFP-tagged) - Human protection of telomeres 1 homolog (S. pombe) (POT1), transcript variant 4 |
CNY 7,030.00 |
