United States
Germany
Japan
United Kingdom
China
CAP1 (NM_006367) Human Untagged Clone
CAT＃: SC321219
CAP1 (untagged)-Human CAP, adenylate cyclase-associated protein 1 (yeast) (CAP1), transcript variant 1
CNY 5,488.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CAP; CAP1-PEN |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_006367.2
GCTGATCGCAGTCCGGAGGTGAGGCGGAACTCTGAGGTGGTCCATTATGGCTGACATGCA
AAATCTGGTAGAAAGATTGGAGAGGGCAGTGGGCCGCCTGGAGGCAGTATCTCATACCTC TGACATGCACCGTGGGTATGCAGACAGTCCTTCAAAAGCAGGAGCAGCTCCATATGTGCA GGCATTTGACTCGCTGCTTGCTGGTCCTGTGGCAGAGTACTTGAAGATCAGTAAAGAGAT TGGGGGAGACGTGCAGAAACATGCGGAGATGGTCCACACAGGTTTGAAGTTGGAGCGAGC TCTGTTGGTTACAGCTTCTCAGTGTCAACAGCCAGCAGAAAATAAGCTTTCCGATTTGTT GGCACCCATCTCAGAGCAGATCAAAGAAGTGATAACCTTTCGGGAGAAGAACCGAGGCAG CAAGTTGTTTAATCACCTGTCAGCTGTCAGCGAAAGTATCCAGGCCCTGGGCTGGGTGGC TATGGCTCCCAAGCCTGGCCCTTATGTGAAAGAAATGAATGATGCCGCCATGTTTTATAC AAACCGAGTCCTCAAAGAGTACAAAGATGTGGATAAGAAGCATGTAGACTGGGTCAAAGC TTATTTAAGTATATGGACAGAGCTGCAGGCTTACATTAAGGAGTTCCATACCACCGGACT GGCCTGGAGCAAAACGGGGCCTGTGGCAAAAGAACTGAGCGGACTGCCATCTGGACCCTC TGCCGGATCAGGTCCTCCTCCCCCTCCACCAGGCCCCCCTCCTCCCCCAGTCTCTACCAG TTCAGGCTCAGATGAGTCTGCTTCCCGCTCAGCACTGTTCGCGCAGATTAATCAGGGGGA GAGCATTACACATGCCCTGAAACATGTATCTGATGACATGAAGACTCACAAGAACCCTGC CCTGAAGGCTCAGAGTGGTCCAGTACGCAGTGGCCCCAAACCATTCTCTGCACCTAAACC CCAAACCAGCCCATCCCCCAAACGAGCCACAAAGAAGGAGCCAGCTGTACTTGAACTGGA GGGCAAGAAGTGGAGAGTGGAAAATCAGGAAAATGTTTCCAACCTGGTGATTGAGGACAC AGAGCTGAAACAGGTGGCTTACATATACAAGTGTGTCAACACGACATTGCAAATCAAGGG CAAAATTAACTCCATTACAGTAGATAACTGTAAGAAACTTGGCCTGGTATTCGATGACGT GGTGGGCATTGTGGAGATAATCAACAGTAAGGATGTCAAAGTTCAGGTAATGGGTAAAGT GCCAACCATATCCATCAACAAAACAGATGGCTGCCATGCTTACCTGAGCAAGAATTCCCT GGATTGTGAAATAGTCAGTGCCAAATCTTCCGAGATGAATGTCCTCATTCCTACAGAAGG CGGTGACTTTAATGAATTCCCAGTTCCTGAGCAGTTCAAGACCCTATGGAACGGGCAGAA GTTGGTCACCACAGTGACAGAAATTGCTGGATAAGCGAAGTGCCACTGGGTTCTTTGCCC TCCCTTCACACCATGGGATAAATCTGTATCAAGACGGTTCTTTTCTAGATTTCCTCTACC TTTTTGCTCTTAAAACTGCTTCTCTGCTCTGAGAAGCACAGCTACCTGCCTTCACTGAAA TATACCTCAGGCTGAAATTTGGGGTGGGATAGCAGGTCAGTTGATCTTCTGCAGGAAGGT GCAGCTTTTCCATATCAGCTCAACCACGCCGCCAGTCCATTCTTAAGGAACTGCCGACTA GGACTGATGATGCATTTTAGCTTTGAGCTTTTGGGGGTTATTCTACCAACAAACAGTCCA TTGGAAAGAAAACAGTCCCTGGAATTAACAGATCAGAATGTTCACACTGGTTAATCTTTT TTTAACAATGAGCATGAAGGTAGCAGAAGCTGGTGTGTTTCCAGATGGTTCTTCTAACCA AACTAATTTTTCACTGTTGACAAGCGAGGCAAGGGTTGCACTGGACCAAAGGCTGAGGCT TGGCCATCTAGCATTCCATACAAAATTGTTTCCTATAAGCATTCCTTTTATTCTCTATTC TATCCTGGGTCTGCCTCAACCGTGAGATAGGAGAGTCTCTGGTACTAGCTGCTGTAGCAG TGCCCTTCATCCAGGGCAGTTAATGGAGTCTTGGACCCTTTCTTTCTCTGGGATCCCTGC CCAGCACCTTCCTATAGAGATGACTTTAAAAGGAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_006367 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_006367.2, NP_006358.1 |
| RefSeq Size | 2614 bp |
| RefSeq ORF | 1428 bp |
| Locus ID | 10487 |
| UniProt ID | Q01518 |
| Domains | CAP, CARP |
| Protein Families | Druggable Genome |
| Gene Summary | The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2016] Transcript Variant: This variant (1) encodes the longer isoform (a). Variants 1, 2, and 4-10 encode the same isoform (a). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Cyclase associated protein (CAP) and the physiological disassembly of actin
,Normoyle, KP;,
Thesis
[CAP1]
|
|
Cyclase-associated Protein (CAP) Acts Directly on F-actin to Accelerate Cofilin-mediated Actin Severing across the Range of Physiological pH
,Kieran P. M. Normoyle and William M. Brieher,
J. Biol. Chem., Oct 2012; 287: 35722 - 35732.
[CAP1]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201394 | CAP1 (Myc-DDK-tagged)-Human CAP, adenylate cyclase-associated protein 1 (yeast) (CAP1), transcript variant 1 |
CNY 5,488.00 |
|
| RC201394L1 | Lenti ORF clone of Human CAP, adenylate cyclase-associated protein 1 (yeast) (CAP1), transcript variant 1, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC201394L2 | Lenti ORF clone of Human CAP, adenylate cyclase-associated protein 1 (yeast) (CAP1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC201394L3 | Lenti ORF clone of Human CAP, adenylate cyclase-associated protein 1 (yeast) (CAP1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201394L4 | Lenti ORF clone of Human CAP, adenylate cyclase-associated protein 1 (yeast) (CAP1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG201394 | CAP1 (tGFP-tagged) - Human CAP, adenylate cyclase-associated protein 1 (yeast) (CAP1), transcript variant 1 |
CNY 7,088.00 |
