SEP15 (NM_203341) Human Untagged Clone

CAT#: SC321079

41532 (untagged)-Human 15 kDa selenoprotein (SEP15), transcript variant 2 (10ug), (Note: selenocysteine protein, Internal stop codon present. see reference data summary below)



  "NM_203341" in other vectors (4)

CNY 3,696.00

CNY 3,990.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00


Rabbit Polyclonal Anti-SEP15 Antibody
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Type Human Untagged Clone
Synonyms SEP15
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_203341.1 GGGGAGGCAGCCAGAAACCTGCGGAAAATGGTAGCGATGGCGGCTGGGCCGAGTGGGTGT
CTGGTGCCGGCGTTTGGGCTACGGTTGTTGTTGGCGACTGTGCTTCAAGCGGTGTCTGCT
TTTGGGGCAGAGTTTTCATCGGAGGCATGCAGAGAGTTAGGCTTTTCTAGCAACTTGCTT
TGCAGCTCTTGTGATCTTCTCGGACAGTTCAACCTGCTTCAGCTGGATCCTGATTGCAGA
GGATGCTGTCAGGAGGAAGCACAATTTGAAACCAAAAAGCTGTATGCAGGAGCTATTCTT
GAAGTTTGTGGATGAAAATTGGGAAGGTTCCCTCAAGTCCAAGTATGTCCGTGGTTCAGA
CCCTGTATTAAAGCTTTTGGACGACAATGGGAACATTGCTGAAGAACTGAGCATTCTCAA
ATGGAACACAGACAGTGTAGAAGAATTCCTGAGTGAAAAGTTGGAACGCATATAAATCTT
GCTTAAATTTTGTCCTATCCTTTTGTTACCTTATCAAATGAAATATTACAGCACCTAGAA
AATAATTTAGTTTTGCTTGCTTCCATTGATCAGTCTTTTACTTGAGGCATTAAATATCTA
ATTAAATCGTGAAATGGCAGTATAGTCCATGATATCTAAGGAGTTGGCAAGCTTAACAAA
ACCCATTTTTTATAAATGTCCATCCTCCTGCATTTGTTGATACCACTAACAAAATGCTTT
GTAACAGACTTGCGGTTAATTATGCAAATGATAGTTTGTGATAATTGGTCCAGTTTTACG
AACAACAGATTTTTAAATTAGAGAGGTTAACAAGACAGATGATTACTATGCCTCATGTGC
TGTGTGCTCTTTGAAAGGAATGACAGCAGACTACAAAGCAAATAAGATATACTGAGCCTC
AACAGATTGCCTGCTCCTCAGAGTCTCTCCTATTTTTGTATTACCCAGCTTTCTTTTTAA
TACAAATGTTATTTATAGTTTACAATGAATGCACTGCATAAAAACTTTGTAGCTTCATTA
TTGTAAAACATATTCAAGATCCTACAGTAAGAGTGAAACATTCACAAAGATTTGCGTTAA
TGAAGACTACACAGAAAACCTTTCTAAGGATTTGTGTGGATCAGATACATACTTGGCAAA
TTTTTGAGTTTTACATTCTTACAGAAAAGTCCATTTAAAAGTGATCATTTGTAAGACCAA
AATATAAATAAAAAGTTACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_203341
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). The expression of this clone is not guaranteed due to the nature of selenoproteins.
OTI Annotation This clone encodes a selenoprotein containing the rare amino acid selenocysteine (Sec). Sec is encoded by UGA codon, which normally signals translational termination. Expression of this clone is not guaranteed due to the nature of selenoproteins.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_203341.1, NP_976086.1
RefSeq Size 1801 bp
Locus ID 9403
UniProt ID O60613
Gene Summary The protein encoded by this gene belongs to the SEP15/selenoprotein M family. The exact function of this protein is not known; however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this protein in the ER, where it may play a role in protein folding. It has also been suggested to have a role in cancer etiology. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2016]
Transcript Variant: This variant (2) lacks an exon in the 3' coding region, which results in a frameshift compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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