United States
Germany
Japan
United Kingdom
China
BIGM103 (SLC39A8) (NM_022154) Human Untagged Clone
CAT＃: SC320928
SLC39A8 (untagged)-Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1
CNY 3,656.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BIGM103; CDG2N; LZT-Hs6; PP3105; ZIP8 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_022154.5
CCGCGGACCTGTCAGAGATACAGAGGTTGTGGGGGCGGGAGACAGAAAGAGAGAGAGATC
CAGAGACCGAGTCTTACGTTGACACGCAGAGAGAAAGACGCAGAGACAGACAAACAAACA GATAGGAGAGGCTCTCCAGGAGGCCGGGGGGCCCACTCCGCCTATCGCTCCCCTCGGCTA CGCTGCCACTTCAATGCCCCGCAGGTCGCGAGCTGCTGTTCTTTCGAAGGCGTCGGAGAA CCAGGGGCGTCCCGCGCCACCTCTGACTCGGAGCAGCGCCGAGCACTGACGCTCCCGCCC TTGGGCAAGGACGCCAGTGCGCCCGCGCGCGTCCCTCTGCGCGGCAGCCCGTCGCGGGCC CTCAAGGGGAAGCCCAGGCCAGGATGGCCCCGGGTCGCGCGGTGGCCGGGCTCCTGTTGC TGGCGGCCGCCGGCCTCGGAGGAGTGGCGGAGGGGCCAGGGCTAGCCTTCAGCGAGGATG TGCTGAGCGTGTTCGGCGCGAATCTGAGCCTGTCGGCGGCGCAGCTCCAGCACTTGCTGG AGCAGATGGGAGCCGCCTCCCGCGTGGGCGTCCCGGAGCCTGGCCAGCTGCACTTCAACC AGTGTTTAACTGCTGAAGAGATCTTTTCCCTTCATGGCTTTTCAAATGCTACCCAAATAA CCAGCTCCAAATTCTCTGTCATCTGTCCAGCAGTCTTACAGCAATTGAACTTTCACCCAT GTGAGGATCGGCCCAAGCACAAAACAAGACCAAGTCATTCAGAAGTTTGGGGATATGGAT TCCTGTCAGTGACGATTATTAATCTGGCATCTCTCCTCGGATTGATTTTGACTCCACTGA TAAAGAAATCTTATTTCCCAAAGATTTTGACCTTTTTTGTGGGGCTGGCTATTGGGACTC TTTTTTCAAATGCAATTTTCCAACTTATTCCAGAGGCATTTGGATTTGATCCCAAAGTCG ACAGTTATGTTGAGAAGGCAGTTGCTGTGTTTGGTGGATTTTACCTACTTTTCTTTTTTG AAAGAATGCTAAAGATGTTATTAAAGACATATGGTCAGAATGGTCATACCCACTTTGGAA ATGATAACTTTGGTCCTCAAGAAAAAACTCATCAACCTAAAGCATTACCTGCCATCAATG GTGTGACATGCTATGCAAATCCTGCTGTCACAGAAGCTAATGGACATATCCATTTTGATA ATGTCAGTGTGGTATCTCTACAGGATGGAAAAAAAGAGCCAAGTTCATGTACCTGTTTGA AGGGGCCCAAACTGTCAGAAATAGGGACGATTGCCTGGATGATAACGCTCTGCGATGCCC TCCACAATTTCATCGATGGCCTGGCGATTGGGGCTTCCTGCACCTTGTCTCTCCTTCAGG GACTCAGTACTTCCATAGCAATCCTATGTGAGGAGTTTCCCCACGAGTTAGGAGACTTTG TGATCCTACTCAATGCAGGGATGAGCACTCGACAAGCCTTGCTATTCAACTTCCTTTCTG CATGTTCCTGCTATGTTGGGCTAGCTTTTGGCATTTTGGTGGGCAACAATTTCGCTCCAA ATATTATATTTGCACTTGCTGGAGGCATGTTCCTCTATATTTCTCTGGCAGATATGTTTC CAGAGATGAATGATATGCTGAGAGAAAAGGTAACTGGAAGAAAAACCGATTTCACCTTCT TCATGATTCAGAATGCTGGAATGTTAACTGGATTCACAGCCATTCTACTCATTACCTTGT ATGCAGGAGAAATCGAATTGGAGTAATAGAAAATGGAAGATGGTGTTGTTAATAAAGGCA TTTAATAGATAAAAACATCTCCAAAAAGGATTTTGAAGCTGATCCTATTTAGTTAAAAAG ATAATTTTGCTTTCAACCGTAGGTCCAGAAAACTAATTATTGGCATCAGTCTGTGAAATA GTCCATTATTTGTTGTTAAAAATGCTTCAAAAGGTTTTCAGTGTCAGTCTGAGATGCCTG GTATATAGGAGCCTTTGGGAAATACCTATTTTTCAGTATTCCATGCATATTGGATATCAC CATGAAGCAAGAGACATGCATTCTATAATCATGTAGACACTCAGACTCAGGGGAAAATAC AAGTTATATCCTGAAAGCCTTTAAAACTCTATGGTAGGATCAAAGATTCAAATGGTTTCA GAGAGGTTTTATTTCAATTAATTTGTTCTAGTGCTTTCAAGAGCAAGTACATCAAAATGT AGAAGGTAAAATGTATGCAACACTAATATAAATTATTCCAAGTCTTTAAGGAGCCAAAGA AAAAAAAGATTTCTCACAGCTTTTTGTTCTGTTTTGTATTTCAATTAGGAACTTGCAGTA TTATTTTGAAAACCATTCTAAAATAATAGGAGTTAGGAAATAAATAAAGTTTTGCTAGCC CTGCTAAGTTCAGGCTTAGAGGCTTATCGCTAAGTGTAAACTTCACCAGATTCCACGAAA AGCTGGATAGCTTTTTTTCTGACTTATGTTGTGGTTGCACCCCTCACAAATGGCAGAACA GTATGTAAAGCTGGTAACACCTCGGTTTCAGTGCACCATGTGTTTGCTTTGTGAAGGTGA AGAATATGTTGGTTTAGAGAAAGAAATTGGATGTAATTTTATGCAATTTACTTTTAAAGA CAAACATAACTATTTAGCAGAGAATATTTTAATAAATGCAAAACAACAGCTGGACTGCTG TACATCAAGGACAGATTAACTGGAAAACATATGTTCCTTATGTGTGATTGAGAGCCATTC AGAAAAGACTTCCTTTGTGTTCAGCCTATACTTTTCCATATGGTATACCTTGAAAAAAAT TAGCACACCATGGTTATTTTTCTACCTTTTATAAAAGACAGAGCCTGTTTACTCATTTAG AAGATAGAGAAAATTGGTCTAAAATTGAACATCCTAGATTCACACTCCCAAGTCACTTAA GGTGATTTGATGGTGAGGAAAATGATTGACAAAGCCCAACAATGATCTCAGGAATTACAT TTTCCAACAGACCAAAAAATGTTTTCATGTAGCAGCAATGCAGATTTGGTGAATATTTAA TATATATTTTAGTATGTATTTCACTTTATGACTGACAATTAAAAAATATTGTTTGGCCAA ATAGTAAACACCCTTTTGAAACCAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_022154 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_022154.5, NP_071437.3 |
| RefSeq Size | 3309 bp |
| RefSeq ORF | 1383 bp |
| Locus ID | 64116 |
| UniProt ID | Q9C0K1 |
| Domains | Zip |
| Protein Families | Transmembrane |
| Gene Summary | This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008] Transcript Variant: This variant (1) encodes the longest isoform (a). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Zinc transporter ZIP8 (SLC39A8) and zinc influence IFN- expression in activated human T cells
,Tolunay B. Aydemir, Juan P. Liuzzi, Steve McClellan, and Robert J. Cousins,
J. Leukoc. Biol., Aug 2009; 86: 337 - 348. 2009
[SLC39A8]
|
|
The Human Zinc Transporter SLC39A8 (Zip8) is Critical in Zinc-mediated Cytoprotection in Lung Epithelia
,Beth Besecker, Shengying Bao, Barbara Bohacova, Audrey Papp, Wolfgang Sadee, and Daren L Knoell,
Am J Physiol Lung Cell Mol Physiol. published 4 April 2008, 10.1152/ajplung.00057.2008
[SLC39A8]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204200 | SLC39A8 (Myc-DDK-tagged)-Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1 |
CNY 3,656.00 |
|
| RC204200L1 | Lenti ORF clone of Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC204200L2 | Lenti ORF clone of Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC204200L3 | Lenti ORF clone of Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204200L4 | Lenti ORF clone of Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1, mGFP tagged |
CNY 6,056.00 |
|
| RG204200 | SLC39A8 (tGFP-tagged) - Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1 |
CNY 5,256.00 |
|
| SC112817 | SLC39A8 (untagged)-Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1 |
CNY 3,656.00 |
其它BIGM103产品
