United States
Germany
Japan
United Kingdom
China
Heme Oxygenase 1 (HMOX1) (NM_002133) Human Untagged Clone
CAT＃: SC320297
HMOX1 (untagged)-Human heme oxygenase (decycling) 1 (HMOX1)
CNY 2,400.00
CNY 2,950.00
| Cited in 5 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | bK286B10; HMOX1D; HO-1; HSP32 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_002133 edited
CTCTCGAGCGTCCTCAGCGCAGCCGCCGCCCGCGGAGCCAGCACGAACGAGCCCAGCACC GGCCGGATGGAGCGTCCGCAACCCGACAGCATGCCCCAGGATTTGTCAGAGGCCCTGAAG GAGGCCACCAAGGAGGTGCACACCCAGGCAGAGAATGCTGAGTTCATGAGGAACTTTCAG AAGGGCCAGGTGACCCGAGACGGCTTCAAGCTGGTGATGGCCTCCCTGTACCACATCTAT GTGGCCCTGGAGGAGGAGATTGAGCGCAACAAGGAGAGCCCAGTCTTCGCCCCTGTCTAC TTCCCAGAAGAGCTGCACCGCAAGGCTGCCCTGGAGCAGGACCTGGCCTTCTGGTACGGG CCCCGCTGGCAGGAGGTCATCCCCTACACACCAGCCATGCAGCACTATGTGAAGCGGCTC CACGAGGTGGGGCGCACAGAGCCCGAGCTGCTGGTGGCCCACGCCTACACCCGCTACCTG GGTGACCTGTCTGGGGGCCAGGTGCTCAAAAAGATTGCCCAGAAAGCCCTGGACCTGCCC AGCTCTGGCGAGGGCCTGGCCTTCTTCACCTTCCCCAACATTGCCAGTGCCACCAAGTTC AAGCAGCTCTACCGCTCCCGCATGAACTCCCTGGAGATGACTCCCGCAGTCAGGCAGAGG GTGATAGAAGAGGCCAAGACTGCGTTCCTGCTCAACATCCAGCTCTTTGAGGAGTTGCAG GAGCTGCTGACCCATGACACCAAGGACCAGAGCCCCTCACGGGCACCAGGGCTTCGCCAG CGGGCCAGCAACAAAGTGCAAGATTCTGCCCCCGTGGAGACTCCCAGAGGGAAGCCCCCA CTCAACACCCGCTCCCAGGCTCCGCTTCTCCGATGGGTCCTTACACTCAGCTTTCTGGTG GCGACAGTTGCTGTAGGGCTTTATGCCATGTGAATGCAGGCATGCTGGCTCCCAGGGCCA TGAACTTTGTCCGGTGGAAGGCCTTCTTTCTAGAGAGGGAATTCTCTTGGCTGGCTTCCT TACCGTGGGCACTGAAGGCTTTCAGGGCCTCCAGCCCTCTCACTGTGTCCCTCTCTCTGG AAAGGAGGAAGGAGCCTATGGCATCTTCCCCAACGAAAAGCACATCCAGGCAATGGCCTA AACTTCAGAGGGGGCGAAGGGATCAGCCCTGCCCTTCAGCATCCTCAGTTCCTGCAGCAG AGCCTGGAAGACACCCTAATGTGGCAGCTGTCTCAAACCTCCAAAAGCCCTGAGTTTCAA GTATCCTTGTTGACACGGCCATGACCACTTTCCCCGTGGGCCATGGCAATTTTTACACAA ACCTGAAAAGATGTTGTGTCTTGTGTTTTTGTCTTATTTTTGTTGGAGCCACTCTGTTCC TGGCTCAGCCTCAAATGCAGTATTTTTGTTGTGTTCTGTTGTTTTTATAGCAGGGTTGGG GTGGTTTTTTGAGCCATGCGTGGGTGGGGAGGGAGGTGTTTAACGGCACTGTGGCCTTGG TCTAACTTTTGTGTGAAATAATAAACAACATTGTCTGATAGTAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_002133 |
| Insert Size | 1600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002133.1, NP_002124.1 |
| RefSeq Size | 1550 bp |
| RefSeq ORF | 867 bp |
| Locus ID | 3162 |
| UniProt ID | P09601 |
| Domains | Heme_oxygenase |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Porphyrin and chlorophyll metabolism |
| Gene Summary | Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008] |
Citations (5)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Downregulation of heme oxygenase 1 (HO-1) activity in hematopoietic cells enhances their engraftment after transplantation
,null,
Cell transplantation
,PubMed ID 27412411
[HMOX1]
|
|
Activation of the complement cascade enhances motility of leukemic cells by downregulating expression of HO-1
,null,
Leukemia
,PubMed ID 27451975
[HMOX1]
|
|
Myeloperoxidase Oxidized LDL Interferes with Endothelial Cell Motility through miR-22 and Heme Oxygenase 1 Induction: Possible Involvement in Reendothelialization of Vascular Injuries
,null,
Mediators of Inflammation
,PubMed ID 25530680
[HMOX1]
|
|
The Cytoprotective Enzyme Heme Oxygenase-1 Suppresses Ebola virus Replication
,Hill-Batorski, L;Halfmann, P;Neumann, G;Kawaoka, Y;,
J Virol. 2013 Dec;87(24):13795-802
,PubMed ID 24109237
[HMOX1]
|
|
Induction of Heme Oxygenase-1 In Vivo Suppresses NADPH Oxidase Derived Oxidative Stress
,Srinivasa R Datla, Gregory J Dusting, Trevor A Mori, Caroline J Taylor, Kevin D Croft, and Fan Jiang,
Hypertension. 2007 Oct;50(4):636-42.
[HMOX1]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200463 | HMOX1 (Myc-DDK-tagged)-Human heme oxygenase (decycling) 1 (HMOX1) |
CNY 2,400.00 |
|
| RC200463L1 | Lenti ORF clone of Human heme oxygenase (decycling) 1 (HMOX1), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC200463L2 | Lenti ORF clone of Human heme oxygenase (decycling) 1 (HMOX1), mGFP tagged |
CNY 5,890.00 |
|
| RC200463L3 | Lenti ORF clone of Human heme oxygenase (decycling) 1 (HMOX1), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC200463L4 | Lenti ORF clone of Human heme oxygenase (decycling) 1 (HMOX1), mGFP tagged |
CNY 4,800.00 |
|
| RG200463 | HMOX1 (tGFP-tagged) - Human heme oxygenase (decycling) 1 (HMOX1) |
CNY 4,000.00 |
|
| SC128080 | HMOX1 (untagged)-Human heme oxygenase (decycling) 1 (HMOX1) |
CNY 2,400.00 |
其它Heme Oxygenase 1产品
