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SIRT7 (NM_016538) Human Untagged Clone
CAT＃: SC319613
SIRT7 (untagged)-Human sirtuin 7 (SIRT7)
CNY 5,488.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | SIR2L7 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_016538.1
GTCTCCAGGGGAGCGATGGCAGCCGGGGGTCTGAGCCGCTCCGAGCGCAAAGCGGCGGAG
CGGGTCCGGAGGTTGCGGGAGGAGCAGCAGAGGGAGCGCCTCCGCCAGGTGTCGCGCATC CTGAGGAAGGCGGCGGCGGAGCGCAGCGCCGAGGAGGGCCGGCTGCTGGCCGAGAGCGCG GACCTGGTAACGGAGCTGCAGGGCCGGAGCCGGCGGCGCGAGGGCCTGAAGCGGCGGCAG GAGGAGGTGTGCGACGACCCGGAGGAGCTGCGGGGGAAGGTCCGGGAGCTGGCCAGCGCC GTCCGGAACGCCAAATACTTGGTCGTCTACACAGGCGCGGGAATCAGCACGGCAGCGTCT ATCCCAGACTACCGGGGCCCTAATGGAGTGTGGACACTGCTTCAGAAAGGGAGAAGCGTT AGTGCTGCCGACCTGAGCGAGGCCGAGCCAACCCTCACCCACATGAGCATCACCCGTCTG CATGAGCAGAAGCTGGTGCAGCATGTGGTGTCTCAGAACTGTGACGGGCTCCACCTGAGG AGTGGGCTGCCGCGCACGGCCATCTCCGAGCTCCACGGGAACATGTACATTGAAGTCTGT ACCTCCTGCGTTCCCAACAGGGAGTACGTGCGGGTGTTCGATGTGACGGAGCGCACTGCC CTCCACAGACACCAGACAGGCCGGACCTGCCACAAGTGTGGGACCCAGCTGCGGGACACC ATTGTGCACTTTGGGGAGAGGGGGACGTTGGGGCAGCCTCTGAACTGGGAAGCGGCGACC GAGGCTGCCAGCAGAGCAGACACCATCCTGTGTCTAGGGTCCAGCCTGAAGGTTCTAAAG AAGTACCCACGCCTCTGGTGCATGACCAAGCCCCCTAGCCGGCGGCCGAAGCTTTACATC GTGAACCTGCAGTGGACCCCGAAGGATGACTGGGCTGCCCTGAAGCTACATGGGAAGTGT GATGACGTCATGCGGCTCCTCATGGCCGAGCTGGGCTTGGAGATCCCCGCCTATAGCAGG TGGCAGGATCCCATTTTCTCACTGGCGACTCCCCTGCGTGCTGGTGAAGAAGGCAGCCAC AGTCGGAAGTCGCTGTGCAGAAGCAGAGAGGAGGCCCCGCCTGGGGACCGGGGTGCACCG CTTAGCTCGGCCCCCATCCTAGGGGGCTGGTTTGGCAGGGGCTGCACAAAACGCACAAAA AGGAAGAAAGTGACGTAATCACGTGCTCGATGAAGAACAGTTGGCACTTTGCAGATGGCC AGTGTCACGGTGAAGGCTGGGTTGCCCCCACGGGTCTAGGGAGAACGAACTCTTTGGGGA TGACATTTTCACCGTGACATTTTTAGCCATTTGTCCTTGAGGAAGCCCCTTGCACTGCTG CGGTTGTACCCTGATACGGCCTGGCCATCGAGGACACCTGCCCATCCGGCCTCTGTGTCA AGAGGTGGCAGCCGCACCTTTCTGTGAGAACGGAACTCGGGTTATTTCAGCCCCGGCCTG CAGAGTGGAAGCGCCCAGCGGCCTTTCCTCGCTCACCAGGCCAGTCTCAGGGCCTCACCG TATTTCTACTACTACTTAATGAAAAAGTGTGAACTTTATAGAATCCTCTCTGTACTGGAT GTGCGGCAGAGGGGTGGCTCCGAGCCTCGGCTCTATGCAGACCTTTTTATTTCTATTAAA CGTTTCTGCACTGGCAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_016538 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_016538.1, NP_057622.1 |
| RefSeq Size | 1718 bp |
| RefSeq ORF | 1203 bp |
| Locus ID | 51547 |
| UniProt ID | Q9NRC8 |
| Domains | SIR2 |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts
,null,
American Journal of Physiology - Lung Cellular and Molecular Physiology
,PubMed ID 28385812
[SIRT7]
|
|
Altered Sirtuin 7 Expression is Associated with Early Stage Breast Cancer
,Aljada, A;Saleh, AM;Alkathiri, M;Shamsa, HB;Al-Bawab, A;Nasr, A;,
Breast Cancer (Auckl)
,PubMed ID 25922576
[SIRT7]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205658 | SIRT7 (Myc-DDK-tagged)-Human sirtuin 7 (SIRT7) |
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|
| RC205658L1 | Lenti ORF clone of Human sirtuin 7 (SIRT7), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC205658L2 | Lenti ORF clone of Human sirtuin 7 (SIRT7), mGFP tagged |
CNY 5,890.00 |
|
| RC205658L3 | Lenti ORF clone of Human sirtuin 7 (SIRT7), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205658L4 | Lenti ORF clone of Human sirtuin 7 (SIRT7), mGFP tagged |
CNY 5,890.00 |
|
| RG205658 | SIRT7 (tGFP-tagged) - Human sirtuin 7 (SIRT7) |
CNY 7,088.00 |
