AEBP2 (NM_001114176) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_001114176, the custom clone sequence may differ by one or more nucleotides ATGGCCGCCGCTATCACCGACATGGCCGACCTGGAGGAGCTCTCCCGCCTGAGCCCTCTG CCCCCCGGCAGCCCGGGTTCGGCGGCGCGGGGCCGGGCTGAGCCCCCCGAGGAGGAGGAG GAAGAGGAGGAGGAGGAAGAGGAGGCGGAGGCCGAGGCGGTGGCGGCGCTGCTGCTGAAC GGCGGCAGCGGTGGGGGCGGCGGAGGCGGCGGCGGAGGAGTGGGGGGCGGCGAGGCAGAG ACGATGTCGGAGCCGAGCCCCGAGAGCGCCAGCCAGGCCGGGGAGGACGAAGACGAGGAG GAGGACGACGAGGAGGAGGAAGATGAGAGCAGCAGCAGCGGCGGGGGTGAGGAGGAGAGT AGCGCCGAGAGCCTGGTGGGCAGCAGCGGCGGGAGCAGCAGCGACGAGACCCGCTCGTTG AGCCCCGGCGCCGCCAGCAGCAGCAGCGGGGATGGGGACGGCAAGGAGGGCCTGGAGGAG CCCAAGGGACCGCGGGGCAGCCAGGGCGGCGGCGGGGGCGGCAGCAGTAGCAGCAGCGTA GTCTCCAGCGGCGGCGACGAGGGCTACGGGACTGGGGGAGGCGGAAGCAGCGCGACCTCC GGGGGCCGGCGGGGCAGCTTGGAGATGTCGTCGGATGGGGAACCCCTGAGCCGCATGGAC TCGGAGGACAGCATAAGCAGTACTATAATGGATGTAGACAGCACAATTTCCAGTGGGCGT TCAACTCCAGCAATGATGAATGGACAAGGAAGCACTACTTCTTCAAGCAAAAATATTGCC TATAATTGTTGTTGGGACCAGTGCCAGGCTTGCTTCAACTCTAGCCCAGATCTGGCAGAT CACATCCGTTCCATACATGTAGATGGTCAGCGAGGAGGGGTATTTGTTTGCTTATGGAAA GGTTGTAAAGTATATAACACTCCATCTACCAGTCAAAGTTGGTTACAAAGGCATATGCTG ACACACAGTGGAGACAAACCTTTCAAGTGTGTTGTTGGTGGCTGCAATGCCAGCTTTGCT TCTCAGGGAGGGCTAGCTCGTCATGTACCCACACACTTCAGTCAGCAGAACTCCTCAAAA GTTTCTAGCCAGCCAAAGGCCAAAGAAGAATCTCCTTCTAAAGCTGGAATGAACAAAAGG AGGAAATTAAAGAACAAAAGACGACGCTCATTACCACGGCCACATGATTTCTTCGATGCA CAAACACTGGATGCGATAAGACATCGAGCCATATGCTTTAACCTCTCAGCTCATATAGAA AGTTTAGGGAAGGGACACAGTGTTGTTTTTCATAGTACTGTAATAGCTAAGAGAAAAGAA GATTCTGGGAAGATCAAACTTTTGCTTCATTGGATGCCTGAAGACATTCTGCCTGATGTG TGGGTGAATGAAAGTGAACGACATCAGTTAAAAACTAAAGTAGTTCATTTATCAAAGCTA CCCAAAGATACTGCCTTGCTTTTGGACCCAAACATATACAGAACAATGCCGCAGAAGAGG TTGAAGAGAACTCTGATAAGAAAAGTGTTCAATTTGTATTTAAGCAAACAG
Restriction Sites	Please inquire
ACCN	NM_001114176
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001114176.1, NP_001107648.1
RefSeq Size	5099 bp
RefSeq ORF	1554 bp
Locus ID	121536
UniProt ID	Q6ZN18
Gene Summary	DNA-binding transcriptional repressor. May interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) lacks a segment in the 3' coding region, compared to variant 1, which results in a protein (isoform B) with a longer and distinct C-terminus, compared to isoform A.

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