KALRN (NM_001024660) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	ARHGEF24; CHD5; CHDS5; DUET; DUO; HAPIP; TRAD
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >SC318742 representing NM_001024660. Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGACGGACCGCTTCTGGGACCAGTGGTATCTCTGGTATCTCCGCTTGCTCCGGCTGCTGGATCGAGGG TCTTTTCGGAATGATGGTTTGAAAGCTTCTGATGTCCTTCCTATCCTAAAGGAAAAGGTGGCCTTCGTG TCTGGGGGTCGTGATAAGCGAGGCGGACCCATCCTGACCTTCCCTGCTCGCAGCAATCATGACAGAATA AGACAGGAAGACCTGCGGAAACTCGTGACGTATTTGGCCAGCGTGCCAAGTGAGGACGTGTGCAAACGT GGCTTCACTGTCATCATCGACATGCGGGGCTCCAAGTGGGACCTCATCAAGCCCCTCCTCAAAACGCTG CAGGAAGCCTTTCCAGCTGAGATCCATGTGGCCCTCATCATTAAACCCGACAACTTCTGGCAGAAACAG AAGACCAACTTTGGCAGCTCCAAATTCATCTTTGAGACGAGCATGGTATCTGTGGAGGGCCTCACAAAG CTGGTGGACCCCTCCCAGCTGACGGAGGAGTTTGATGGCTCCCTGGACTACAACCATGAGGAGTGGATC GAACTGCGGCTCTCCCTGGAGGAGTTCTTCAACAGCGCCGTGCACCTGCTCTCGCGCCTCGAGGACCTC CAGGAGATGCTAGCCCGGAAGGAGTTTCCTGTGGATGTGGAGGGCTCTCGGCGGCTCATTGACGAACAC ACACAGCTCAAGAAAAAGGTGCTGAAGGCCCCTGTGGAGGAGCTGGACCGGGAGGGGCAGCGGCTGCTG CAGTGCATCCGCTGCAGCGACGGCTTCTCAGGACGCAACTGCATCCCGGGCAGTGCTGACTTCCAGAGC CTGGTGCCCAAGATCACCAGTCTCCTGGACAAGCTGCACTCCACCCGGCAGCACCTGCACCAGATGTGG CATGTGCGCAAGCTCAAGCTGGACCAGTGCTTTCAGCTGCGGCTCTTCGAGCAGGATGCTGAGAAGATG TTTGACTGGATAAGCCACAACAAGGAGTTATTCCTCCAGAGCCACACGGAGATCGGAGTCAGCTACCAG TACGCCCTTGACCTCCAGACGCAGCACAATCACTTTGCCATGAACTCCATGAATGCCTATGTCAACATC AACCGCATCATGTCCGTGGCTTCCCGCCTCTCTGAGGCCGGTCATTATGCCTCACAACAAATCAAGCAG ATCTCCACCCAGCTGGACCAGGAGTGGAAGAGCTTCGCTGCTGCCCTGGATGAACGCAGCACCATCCTC GCCATGTCTGCTGTGTTCCACCAGAAGGCTGAGCAGTTCCTGTCGGGAGTGGATGCCTGGTGCAAGATG TGCAGTGAAGGTGGTCTGCCATCCGAGATGCAAGACCTAGAGCTGGCAATCCACCACCACCAGACCTTG TATGAGCAGGTGACCCAAGCCTACACAGAGGTCAGCCAGGATGGCAAAGCACTACTTGATGTGCTGCAG CGGCCCCTGAGCCCTGGGAACTCCGAATCCCTCACGGCCACAGCCAACTACTCCAAGGCAGTGCACCAG GTGCTGGACGTGGTGCATGAGGTGTTACATCACCAGCGACGGCTGGAGAGCATCTGGCAGCACCGCAAG GTGCGGCTCCACCAGCGGCTGCAGCTCTGCGTCTTCCAGCAGGATGTACAGCAGGTGTTGGACTGGATT GAAAACCATGGTGAGGCCTTTCTCAGCAAACACACTGGAGTTGGGAAGTCCCTACATCGAGCCCGGGCC CTGCAGAAGAGGCATGATGACTTTGAAGAGGTGGCTCAGAATACGTACACCAATGCGGACAAGCTCCTA GAAGCAGCAGAGCAGTTGGCTCAGACGGGGGAATGTGACCCCGAGGAGATCTACAAGGCAGCTCGACAC CTGGAGGTGCGCATCCAAGACTTCGTGCGCAGGGTGGAGCAGCGGAAGCTTCTCCTGGACATGTCTGTT TCCTTCCACACACACACCAAAGAGTTGTGGACATGGATGGAAGACCTTCAGAAGGAGATGTTGGAGGAT GTCTGTGCAGATTCTGTGGATGCAGTCCAGGAACTGATCAAGCAGTTCCAGCAGCAGCAGACCGCCACT CTAGATGCCACACTCAATGTCATCAAGGAAGGCGAAGACCTTATCCAGCAGCTCAGGTCAGCGCCTCCC TCCCTCGGGGAGCCCAGCGAGGCCAGGGACTCGGCTGTGTCCAACAACAAAACACCCCACAGCAGCTCC ATCAGCCACATCGAGTCGGTCCTGCAGCAGCTTGATGATGCCCAGGTGCAGATGGAGGAGCTGTTCCAC GAGCGGAAGATCAAGCTGGACATCTTCCTGCAACTGCGCATCTTTGAGCAGTACACCATCGAGGTGACA GCAGAGCTAGACGCCTGGAATGAAGACTTGCTTCGGCAGATGAATGACTTCAACACAGAGGACCTAACC CTGGCAGAACAGCGGCTGCAGCGCCACACAGAACGGAAGCTAGCCATGAACAACATGACCTTTGAGGTT ATCCAGCAGGGACAGGATCTGCACCAGTACATCACGGAGGTCCAGGCATCAGGAATTGAGTTGATCTGT GAAAAAGACATTGATCTGGCAGCCCAGGTGCAAGAGTTATTGGAATTTCTCCATGAGAAGCAGCATGAA TTGGAGCTCAATGCAGAGCAGACTCATAAGCGGCTAGAGCAGTGCCTCCAATTACGTCACCTCCAGGCT GAAGTCAAACAGGTTCTGGGATGGATCCGCAATGGAGAGTCAATGCTCAACGCCAGCCTGGTCAATGCC AGCTCTTTGTCGGAAGCAGAGCAGCTGCAGCGGGAGCACGAGCAGTTCCAACTGGCCATCGAGTCCCTC TTTCATGCCACTTCCTTGCAGAAGACGCACCAGAGTGCCCTGCAGGTACAGCAGAAAGCCGAGGTGCTG CTCCAGGCCGGCCACTACGATGCCGATGCCATCCGGGAATGTGCTGAGAAGGTGGCCCTCCACTGGCAG CAGCTCATGCTGAAGATGGAAGACCGGCTAAAATTGGTCAATGCCTCTGTGGCCTTTTACAAAACTTCT GAACAGGTGTGTAGTGTCCTGGAGAGCTTAGAGCAAGAATACCGGAGAGATGAGGACTGGTGTGGTGGA CGAGATAAGCTGGGGCCAGCAGCAGAGATCGACCATGTCATTCCCCTCATCAGCAAACATTTGGAACAA AAGGAGGCCTTTCTTAAGGCCTGCACCCTGGCTCGGCGGAATGCTGAGGTGTTTCTCAAGTACATCCAC AGGAACAACGTCAGCATGCCCAGTGTCGCCAGCCACACTCGGGGACCCGAGCAACAAGTGAAAGCCATC CTGAGTGAGCTCCTGCAGAGGGAGAATCGCGTGCTGCATTTCTGGACCTTGAAGAAGCGGCGGTTAGAC CAATGCCAGCAATATGTGGTGTTCGAGCGCAGCGCTAAGCAGGCGCTTGACTGGATCCAAGAAACAGGT GAATTTTACCTCTCAACACATACCTCCACTGGAGAGACCACAGAGGAGACTCAGGAACTGCTGAAAGAA TATGGGGAATTCAGGGTGCCTGCCAAGCAAACAAAGGAGAAGGTGAAGCTTCTGATTCAGCTGGCCGAT AGCTTTGTGGAAAAAGGCCACATTCATGCCACGGAGATAAGGAAATGGGTGACCACGGTGGACAAGCAC TACAGAGATTTCTCCCTGAGGATGGGAAAGTACCGATACTCACTGGAGAAAGCCCTAGGAGTCAACACA GAGGATAATAAGGACCTGGAGCTGGATATTATCCCAGCAAGCCTTTCGGATCGGGAGGTCAAGCTGCGG GACGCCAACCACGAAGTCAATGAAGAGAAGCGGAAGTCAGCCCGGAAGAAAGAATTTATTATGGCTGAA CTACTCCAGACAGAGAAGGCTTATGTAAGGGATTTGCATGAGTGCTTAGAGACCTACCTGTGGGAAATG ACCAGTGGTGTGGAGGAGATCCCCCCTGGGATCCTCAATAAAGAGCATATCATCTTTGGCAACATCCAA GAGATCTACGATTTCCATAACAACATCTTCCTCAAAGAGCTGGAGAAGTACGAGCAACTGCCTGAGGAT GTGGGACACTGCTTTGTTACCTGGGCAGACAAATTTCAGATGTATGTCACCTACTGTAAAAACAAGCCT GATTCCAACCAGCTTATCCTGGAGCATGCGGGCACCTTCTTTGATGAGATACAACAGCGGCATGGTCTG GCCAACTCCATCTCTTCCTACCTAATTAAGCCTGTCCAAAGGATCACCAAATATCAACTGCTCCTGAAG GAACTTTTAACTTGCTGTGAAGAAGGGAAAGGGGAGCTCAAGGATGGCCTGGAGGTGATGCTCAGTGTC CCAAAGAAAGCCAATGATGCCATGCATGTCAGCATGCTGGAAGGGTTCGACGAGAACCTGGATGTGCAG GGGGAGTTGATTCTCCAGGATGCCTTTCAAGTGTGGGACCCGAAGTCGCTGATCCGGAAGGGGCGGGAG CGGCACTTGTTCCTCTTTGAGATCTCCTTGGTTTTTAGCAAGGAGATCAAAGATTCTTCAGGACACACG AAATATGTTTACAAGAACAAGCTACTGACCTCAGAGCTGGGTGTGACCGAGCACGTGGAGGGCGATCCC TGCAAATTCGCCTTGTGGTCTGGGCGCACCCCATCCTCAGACAATAAAACAGTGCTGAAAGCCTCCAAC ATTGAAACCAAGCAGGAGTGGATCAAGAACATTCGAGAAGTGATTCAAGAAAGGATCATTCACCTGAAA GGAGCTTTAAAGGAGCCACTTCAGCTCCCCAAAACACCAGCCAAACAGAGGAACAATAGTAAGAGGGAT GGAGTGGAGGATATTGACAGCCAGGGGGATGGGAGCAGCCAACCAGACACCATCTCCATTGCTTCTAGG ACCTCTCAGAACACAGTGGACAGTGACAAGCTCTCTGGTGGATGTGAGCTGACAGTGGTCCTCCAGGAC TTCAGTGCGGGCCACAGCAGTGAGCTGACCATCCAGGTGGGGCAGACGGTAGAGCTGCTGGAGCGGCCC AGCGAGCGGCCTGGTTGGTGTCTGGTCCGTACCACCGAACGGAGCCCGCCCTTGGAGGGTCTGGTCCCC AGCAGCGCCCTGTGCATCTCACACTCCCGAAGCAGCGTGGAGATGGACTGCTTCTTCCCCTTGGTGAAA GATGCATACTCTCATTCCTCAAGCGAGAATGGAGGCAAGTCCGAGTCCGTGGCCAACCTGCAGGCCCAG CCCTCCCTGAACTCCATCCACAGTTCCCCGGGTCCCAAGCGCTCCACCAACACTCTTAAGAAGTGGCTG ACGAGTCCTGTGCGTCGGCTTAACAGCGGGAAGGCAGATGGAAACATCAAAAAGCAGAAGAAAGTTCGC GATGGTCGGAAGAGCTTTGACCTGGGATCTCCCAAGCCTGGGGATGAAACAACCCCTCAGGGAGACAGC GCTGATGAGAAGAGCAAGAAAGGTTGGGGTGAAGATGAGCCGGATGAAGAGTCACACACACCCCTCCCA CCACCTATGAAGATTTTTGACAACGACCCTACACAGGATGAAATGTCCTCCTCTTTGCTAGCAGCCCGG CAGGCTTCCACTGAAGTACCTACTGCTGCAGACCTTGTCAATGCAATAGAAAAGTTGGTCAAAAACAAG CTGAGTCTAGAAGGAAGCTCATACCGGGGGAGCTTGAAAGACCCTGCAGGCTGCCTGAATGAGGGGATG GCCCCACCCACACCTCCTAAAAACCCAGAAGAAGAACAGAAAGCCAAGGCCCTGAGAGGCAGGATGTTT GTCCTGAATGAGCTGGTACAGACAGAGAAAGACTATGTCAAGGATCTGGGCATTGTGGTGGAGGGCTTC ATGAAGAGAATAGAAGAAAAGGGTGTCCCTGAGGATATGCGAGGAAAGGACAAAATCGTGTTTGGAAAT ATTCATCAGATTTATGACTGGCATAAGGATTTTTTCCTGGCGGAACTGGAAAAGTGTATCCAGGAGCAA GACAGATTGGCACAGCTCTTTATTAAGCACGAGCGGAAGCTGCACATCTACGTGTGGTATTGTCAGAAT AAGCCGCGCTCAGAGTACATCGTTGCTGAGTATGACGCCTACTTTGAGGAGGTAAAACAGGAGATAAAT CAGAGGCTGACACTGAGTGACTTCCTCATCAAGCCCATTCAGAGAATAACAAAATACCAGTTGCTCCTC AAGGACTTCCTGAGATACAGTGAGAAGGCTGGTTTGGAGTGTTCAGATATTGAGAAAGCAGTGGAGTTA ATGTGCCTTGTTCCCAAACGCTGCAATGACATGATGAATCTAGGACGTCTGCAGGGCTTTGAGGGCACT CTGACTGCTCAGGGGAAGCTGCTGCAGCAGGACACATTCTATGTGATCGAGCTGGATGCAGGCATGCAG TCCCGGACCAAAGAGAGGCGCGTGTTCCTCTTCGAGCAGATTGTCATCTTCAGTGAACTGCTCAGGAAG GGATCCCTCACCCCTGGCTACATGTTCAAAAGGAGCATCAAGATGAATTACTTGGTCCTGGAGGAGAAT GTGGACAATGATCCCTGCAAGTTTGCACTCATGAACAGAGAGACTTCTGAGAGGGTTGTTCTGCAAGCC GCCAACGCTGACATCCAGCAGGCCTGGGTGCAGGACATCAATCAAGTCTTAGAAACACAGCGAGACTTT TTGAATGCACTGCAATCGCCCATTGAGTATCAACGGAAAGAAAGGAGCACAGCTGTGATGAGGTCTCAA CCTGCCAGGCTTCCCCAAGCCAGCCCCAGGCCCTACTCCTCTGTTCCTGCGGGCTCAGAGAAGCCCCCA AAGGGCTCCAGCTATAACCCACCTCTGCCTCCCCTGAAGATATCTACCTCCAATGGCAGTCCAGGGTTT GAATACCACCAGCCTGGGGACAAGTTCGAAGCCAGCAAGCAGAACGACCTGGGAGGCTGCAATGGGACC TCGTCCATGGCCGTGATCAAAGATTACTATGCACTGAAGGAGAATGAAATCTGTGTGAGCCAAGGTGAG GTGGTCCAGGTCCTCGCCGTCAACCAGCAGAACATGTGTCTGGTGTACCAGCCTGCCAGCGACCATTCC CCCGCCGCCGAGGGCTGGGTCCCAGGCAGCATCCTGGCGCCCCTCACCAAAGCCACAGCAGCAGAAAGT AGTGACGGGAGCATCAAGAAGTCATGTTCATGGCATACTCTACGCATGAGAAAGCGGGCGGAAGTGGAG AACACGGGTAAAAATGAAGCCACAGGGCCTCGTAAACCCAAGGATATTCTGGGCAACAAAGTCTCTGTT AAAGAGACGAACAGTTCCGAGGAATCAGAGTGTGATGATCTTGACCCTAATACTAGCATGGAGATCTTA AATCCAAATTTCATCCAAGAAGTGGCCCCAGAATTCCTTGTGCCCTTGGTGGATGTGACCTGCTTGCTT GGGGACACAGTGATACTGCAGTGCAAAGTCTGTGGGCGGCCAAAGCCCACCATCACTTGGAAGGGTCCA GACCAGAACATCCTTGACACTGATAACAGCTCAGCCACATACACGGTCTCCTCTTGTGATTCTGGAGAA ATCACCCTGAAGATCTGTAATCTGATGCCCCAAGACAGTGGGATTTATACCTGCATAGCAACAAATGAC CACGGGACCACATCAACGTCTGCAACAGTCAAAGTGCAAGGTGTTCCAGCAGCCCCTAACCGCCCCATT GCCCAGGAGAGAAGCTGCACCTCCGTGATTCTCCGCTGGCTGCCCCCCTCCAGCACAGGAAACTGCACT ATTTCTGGTTACACTGTGGAGTACAGAGAGGAAGGTTCTCAGATCTGGCAGCAGTCAGTGGCTTCGACC TTGGACACTTACCTCGTCATCGAAGACCTTAGTCCCGGGTGTCCTTATCAGTTCAGAGTCAGTGCCAGT AACCCCTGGGGAATCAGCCTTCCCAGCGAGCCCTCGGAGTTTGTGCGACTTCCAGAATATGATGCTGCT GCTGATGGTGCCACCATTTCTTGGAAGGAAAATTTTGACTCAGCTTACACTGAGCTGAATGAAATTGGA AGAGGCCGTTTCTCTATAGTAAAGAAATGCATTCACAAAGCTACCCGCAAAGATGTGGCTGTGAAATTT GTTAGCAAAAAAATGAAGAAGAAAGAACAGGCTGCCCACGAGGCTGCCCTGCTTCAGCACCTACAGCAC CCCCAGTACATCACTCTCCATGACACCTATGAGTCCCCCACATCCTACATCCTGATCTTGGAACTGATG GATGATGGCCGGCTCTTAGACTACCTTATGAATCATGATGAACTGATGGAGGAAAAAGTAGCTTTCTAT ATCCGAGACATCATGGAGGCTCTGCAGTACCTTCACAACTGCAGGGTTGCACATTTGGACATAAAGCCT GAAAACCTGCTCATTGACCTACGGATTCCAGTGCCTCGAGTGAAGCTCATTGACTTGGAGGATGCTGTC CAGATCTCGGGTCACTTCCACATTCACCACCTGCTGGGGAACCCTGAGTTTGCTGCCCCAGAAGTCATT CAAGGCATCCCCGTCTCCCTGGGGACAGACATCTGGAGCATCGGGGTTCTGACATATGTCATGCTGAGT GGGGTCTCCCCCTTCTTGGATGAGAGCAAAGAGGAGACATGTATCAACGTATGCAGGGTGGATTTCAGC TTCCCCCATGAATACTTCTGTGGTGTGAGCAATGCTGCCAGAGATTTCATCAATGTGATCTTACAGGAA GATTTTCGGAGGCGGCCCACAGCAGCCACATGCTTGCAGCATCCATGGCTGCAGCCCCATAATGGCAGC TACTCTAAGATCCCCCTGGACACCTCCCGCCTAGCATGCTTCATAGAACGTCGCAAGCACCAGAATGAT GTGCGGCCTATTCCCAATGTCAAGAGCTACATTGTCAACCGGGTGAACCAAGGGACGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
Restriction Sites	SgfI-MluI
ACCN	NM_001024660
Insert Size	8961 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001024660.4
RefSeq Size	15982 bp
RefSeq ORF	8961 bp
Locus ID	8997
UniProt ID	O60229
Protein Families	Druggable Genome, Protein Kinase
MW	340.3 kDa
Gene Summary	Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. [provided by RefSeq, Apr 2016] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). There are no publicly available transcripts representing the full-length splicing pattern of this variant; it is inferred from data in PMID:11891045 and from the rat homolog, NM_032062.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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