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ARS2 (SRRT) (NM_015908) Human Untagged Clone
CAT＃: SC318351
SRRT (untagged)-Human serrate RNA effector molecule homolog (Arabidopsis) (SRRT), transcript variant 1
CNY 16,910.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARS2; ASR2; serrate |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC318351 representing NM_015908.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGGTGACAGTGATGACGAGTACGATCGAAGGCGCAGGGACAAGTTCAGAAGAGAGCGCAGCGACTAC GACCGTTCCCGCGAGAGAGATGAAAGACGTCGAGGGGACGATTGGAATGACAGAGAGTGGGACCGTGGC CGTGAGCGCCGTAGTCGGGGTGAATATCGGGACTATGACCGGAATCGGCGAGAGCGCTTCTCGCCACCT CGCCACGAACTCAGCCCGCCACAGAAGCGCATGAGGAGAGACTGGGATGAGCACAGCTCTGACCCATAC CACAGTGGCTATGAGATGCCCTATGCTGGGGGGGGTGGGGGCCCAACTTATGGCCCCCCTCAGCCCTGG GGCCACCCTGACGTCCACATCATGCAGCACCATGTCCTGCCTATCCAGGCCAGGCTGGGCAGCATTGCA GAGATTGACCTGGGTGTGCCGCCGCCCGTGATGAAGACCTTCAAGGAGTTTCTCCTCTCCCTGGATGAC TCGGTGGATGAGACGGAGGCCGTCAAGCGCTATAATGACTACAAGCTGGATTTCCGGAGGCAACAGATG CAGGATTTCTTCCTGGCGCACAAAGATGAGGAGTGGTTTCGGTCTAAGTACCACCCAGATGAGGTGGGG AAGCGTCGGCAGGAGGCCCGGGGGGCCCTGCAAAACCGACTGAGGGTCTTCCTGTCCCTCATGGAGACT GGCTGGTTTGATAACCTTCTCCTGGACATAGACAAAGCTGATGCCATTGTCAAGATGCTGGATGCAGCC GTGATTAAGATGGAAGGAGGCACGGAGAATGATCTTCGCATCCTGGAGCAGGAGGAGGAGGAGGAGCAG GCAGGAAAGCCTGGGGAGCCCAGCAAGAAAGAAGAAGGACGGGCTGGAGCAGGCCTAGGGGACGGGGAG CGCAAAACCAACGACAAGGATGAGAAGAAGGAAGACGGCAAGCAGGCTGAGAATGACAGTTCTAATGAT GACAAAACAAAGAAGTCGGAGGGTGATGGGGACAAGGAAGAGAAGAAAGAAGACTCCGAGAAGGAAGCC AAAAAGAGTAGCAAGAAGCGGAACCGGAAGCACAGTGGTGACGACAGCTTTGACGAGGGCAGCGTGTCA GAGTCTGAGTCGGAGTCAGAGAGCGGCCAGGCTGAGGAGGAGAAGGAGGAGGCCGAAGAAGCGCTCAAG GAGAAGGAGAAGCCCAAGGAAGAAGAATGGGAGAAGCCCAAGGACGCCGCGGGGCTGGAGTGCAAGCCG CGGCCGCTGCATAAGACCTGCTCCCTCTTCATGCGCAACATCGCGCCCAACATCTCCCGGGCCGAGATC ATCTCCCTTTGTAAAAGGTACCCAGGCTTTATGCGGGTGGCGCTCTCAGAGCCCCAGCCAGAGAGGAGG TTTTTCCGTCGTGGCTGGGTGACCTTCGACCGCAGTGTTAACATTAAAGAGATCTGTTGGAACCTGCAG AACATCCGTCTCCGGGAGTGTGAGCTGAGCCCTGGTGTGAACAGGGACCTGACCCGGCGCGTTCGCAAC ATCAACGGCATCACCCAGCACAAGCAGATTGTGCGCAACGACATCAAGCTGGCGGCCAAGCTGATCCAC ACGCTGGATGACAGGACACAGCTTTGGGCCTCAGAACCAGGGACGCCTCCCCTGCCCACGAGCCTGCCC TCGCAAAACCCGATCTTGAAGAATATCACCGACTACCTGATCGAGGAAGTAAGCGCCGAGGAGGAGGAG CTGCTGGGGAGCAGCGGGGGCGCTCCTCCTGAGGAGCCTCCTAAGGAAGGGAACCCGGCAGAGATCAAC GTGGAGCGGGATGAGAAGTTGATTAAGGTCTTGGACAAGCTCCTCCTTTACCTGCGCATCGTGCATTCC TTGGATTATTACAACACCTGTGAGTACCCCAACGAGGACGAGATGCCCAATCGCTGTGGGATCATCCAC GTTCGGGGGCCCATGCCACCCAACCGCATCAGTCACGGGGAAGTGCTGGAGTGGCAGAAGACTTTTGAG GAGAAGCTCACGCCGTTGCTGAGTGTGCGGGAGTCACTCTCAGAGGAAGAGGCCCAGAAGATGGGGCGC AAAGACCCAGAGCAGGAAGTGGAGAAGTTCGTCACCTCCAACACGCAGGAACTGGGCAAGGATAAGTGG CTGTGTCCTCTCAGTGGCAAGAAATTCAAGGGTCCTGAGTTTGTGCGCAAACATATCTTCAACAAGCAT GCAGAGAAAATTGAGGAAGTGAAAAAGGAAGTCGCGTTTTTTAACAACTTCCTCACTGATGCTAAGCGC CCAGCTCTGCCTGAGATCAAGCCAGCCCAGCCACCTGGCCCCGCCCAGATACTCCCCCCAGGTTTGACC CCAGGACTCCCCTACCCACACCAGACTCCCCAGGGCCTGATGCCCTATGGTCAGCCCCGGCCCCCGATC TTGGGCTATGGAGCTGGTGCTGTCCGCCCTGCAGTCCCCACAGGAGGCCCTCCATACCCCCATGCCCCG TATGGTGCTGGTCGAGGGAACTATGATGCCTTCCGAGGCCAGGGAGGTTATCCTGGGAAACCTCGCAAC AGGATGGTTCGTGGAGACCCAAGGGCCATTGTGGAATATCGGGACCTGGATGCCCCAGACGATGTTGAT TTCTTTTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_015908 |
| Insert Size | 2631 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_015908.5 |
| RefSeq Size | 3032 bp |
| RefSeq ORF | 2631 bp |
| Locus ID | 51593 |
| UniProt ID | Q9BXP5 |
| MW | 100.7 kDa |
| Gene Summary | Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214814 | SRRT (Myc-DDK-tagged)-Human serrate RNA effector molecule homolog (Arabidopsis) (SRRT), transcript variant 1 |
CNY 6,416.00 |
|
| RC214814L3 | Lenti ORF clone of Human serrate RNA effector molecule homolog (Arabidopsis) (SRRT), transcript variant 1, Myc-DDK-tagged |
CNY 11,120.00 |
|
| RC214814L4 | Lenti ORF clone of Human serrate RNA effector molecule homolog (Arabidopsis) (SRRT), transcript variant 1, mGFP tagged |
CNY 11,120.00 |
|
| RG214814 | SRRT (tGFP-tagged) - Human serrate RNA effector molecule homolog (Arabidopsis) (SRRT), transcript variant 1 |
CNY 10,170.00 |
|
| SC114586 | SRRT (untagged)-Human serrate RNA effector molecule homolog (Arabidopsis) (SRRT), transcript variant 1 |
CNY 3,656.00 |
