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IRAG1 (NM_001098579) Human Untagged Clone
CAT＃: SC316432
MRVI1 (untagged)-Human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 1
CNY 17,390.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IRAG; JAW1L; MRVI1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC316432 representing NM_001098579.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGGAATGGATTTGACTTGTCCTTTTGGCATCTCCCCAGCCTGTGGAGCCCAGGCCTCTTGGAGCATC TTTGGGGCTGACGCAGCGGAGGTTCCGGGCACACGTGGCCACTCCCAGCAGGAGGCTGCCATGCCCCAC ATTCCCGAGGACGAGGAGCCCCCCGGAGAGCCACAGGCAGCCCAGAGCCCTGCCGGCCAAGGTCCTCCT GCCGCAGGAGTATCTTGCAGTCCAACTCCCACGATTGTCCTGACTGGGGATGCCACTTCACCAGAAGGA GAAACCGACAAAAACCTGGCCAACAGAGTTCACAGTCCCCACAAGAGGCTTTCTCACCGACACTTGAAG GTGTCCACTGCCTCCCTGACATCTGTGGACCCCGCGGGGCACATCATTGACCTGGTGAATGACCAGCTG CCAGACATCAGCATCTCAGAGGAGGACAAGAAGAAAAACCTGGCGCTGCTGGAAGAAGCCAAGTTGGTG AGTGAGCGATTCCTGACCCGCCGTGGGAGGAAGTCCAGGAGCAGCCCCGGAGACTCCCCATCAGCTGTT TCCCCGAACCTCAGCCCCAGCGCTTCTCCTACATCCTCTCGGAGCAACTCACTTACAGTCCCCACCCCG CCAGGTTTGGATGTGTGCAGTGGCCCGCCATCCCCTCTGCCTGGAGCACCACCACAGCAGAAGGGGGAT GAGGCCGACGTCTCTTCACCTCACCCTGGCGAGCCTAACGTCCCCAAAGGGCTAGCTGACAGGAAGCAG AATGACCAGAGGAAAGTGTCTCAGGGCAGGCTGGCTCCTCGTCCTCCTCCAGTTGAGAAGTCCAAAGAG ATTGCAATAGAACAAAAGGAAAACTTCGATCCCCTCCAGTACCCCGAGACCACACCCAAAGGCCTAGCT CCTGTTACAAACAGCAGTGGGAAAATGGCCCTGAACAGCCCTCAGCCTGGCCCCGTGGAGAGCGAGCTG GGGAAGCAGCTCTTGAAAACGGGCTGGGAGGGCAGCCCTCTGCCGAGAAGTCCAACCCAGGATGCGGCA GGAGTGGGTCCCCCAGCCTCCCAGGGGAGAGGCCCAGCTGGAGAGCCGATGGGGCCCGAGGCTGGCTCC AAAGCTGAGCTTCCACCCACTGTGTCCCGGCCCCCGCTGCTGCGAGGGCTCTCCTGGGACAGTGGCCCT GAAGAACCTGGCCCCCGGCTGCAGAAAGTGCTTGCCAAGCTGCCACTGGCAGAGGAAGAAAAGCGTTTT GCAGGCAAGGCCGGCGGCAAGCTGGCCAAGGCCCCTGGTCTCAAAGACTTTCAGATACAAGTGCAGCCC GTGCGGATGCAGAAACTGACCAAGCTCCGAGAGGAGCACATCCTGATGAGAAATCAGAACTTAGTGGGG CTCAAGCTTCCAGACCTTAGTGAAGCAGCTGAGCAGGAAAAAGGGCTTCCTTCTGAACTCTCCCCAGCT ATTGAGGAAGAAGAGTCAAAGAGTGGCTTAGATGTCATGCCTAATATTTCTGATGTGCTGCTGCGCAAA CTGCGGGTCCACAGGAGTCTCCCTGGAAGTGCCCCTCCACTCACTGAAAAGGAAGTTGAGAACGTGTTT GTGCAACTGTCCTTGGCCTTTAGAAATGACAGCTACACTCTGGAATCTAGAATTAACCAGGCTGAAAGG GAACGCAACCTGACAGAGGAGAACACTGAGAAAGAACTGGAAAACTTCAAAGCTTCCATTACGTCCTCA GCTTCACTCTGGCACCACTGTGAGCACCGGGAAACCTACCAGAAGTTGCTGGAGGACATCGCTGTCCTG CACCGCCTGGCTGCCCGCCTCTCCAGCCGAGCTGAGGTGGTAGGCGCCGTCCGCCAGGAAAAGCGCATG TCGAAAGCAACGGAAGTGATGATGCAGTATGTGGAGAATCTAAAGAGGACGTATGAGAAGGACCATGCG GAGCTCATGGAGTTTAAAAAGCTTGCAAATCAGAATTCAAGCCGCAGCTGTGGCCCCTCTGAAGATGGG GTCCCTCGCACGGCACGGTCCATGTCCCTCACGCTGGGAAAGAATATGCCTCGCCGGAGGGTCAGCGTT GCTGTGGTTCCTAAGTTTAATGCCCTGAATCTGCCTGGCCAAACTCCCAGCTCATCATCCATTCCCTCC TTACCAGCCTTGTCGGAATCACCCAATGGGAAAGGCAGCCTACCTGTCACTTCAGCACTGCCTGCACTT TTGGAAAATGGAAAGACAAATGGGGACCCAGATTGTGAAGCCTCTGCTCCTGCGCTGACCCTGAGCTGC CTGGAGGAGCTTAGTCAGGAGACCAAGGCCAGGATGGAGGAAGAAGCCTACAGCAAGGGATTCCAAGAA GGTCTAAAGAAGACCAAAGAACTTCAAGACCTGAAGGAGGAGGAGGAAGAACAGAAGAGTGAGAGTCCT GAGGAACCTGAAGAGGTAGAAGAAACTGAGGAAGAGGAAAAGGGCCCAAGAAGCAGCAAACTTGAAGAA TTGGTCCATTTCTTACAAGTCATGTATCCCAAACTGTGTCAGCACTGGCAAGTGATCTGGATGATGGCT GCAGTGATGCTGGTCTTGACTGTTGTGCTGGGGCTCTACAATTCCTATAACTCTTGTGCAGAGCAGGCT GATGGGCCCCTTGGAAGATCCACTTGCTCGGCAGCCCAGAGGGACTCCTGGTGGAGCTCAGGACTCCAG CATGAGCAGCCTACAGAGCAGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001098579 |
| Insert Size | 2715 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001098579.2 |
| RefSeq Size | 6045 bp |
| RefSeq ORF | 2715 bp |
| Locus ID | 10335 |
| UniProt ID | Q9Y6F6 |
| Protein Families | Transmembrane |
| Protein Pathways | Vascular smooth muscle contraction |
| MW | 98 kDa |
| Gene Summary | This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, and alternative translation start sites, including a non-AUG (CUG) start site, are used. [provided by RefSeq, May 2011] Transcript Variant: This variant (1) encodes isoform a, also known as MRVI1A. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220170 | MRVI1 (Myc-DDK-tagged)-Human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 1 |
CNY 6,616.00 |
|
| RC220170L3 | Lenti ORF clone of Human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 1, Myc-DDK-tagged |
CNY 11,400.00 |
|
| RC220170L4 | Lenti ORF clone of Human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 1, mGFP tagged |
CNY 11,400.00 |
|
| RG220170 | MRVI1 (tGFP-tagged) - Human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 1 |
CNY 10,450.00 |
