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DLL1 (NM_005618) Human Untagged Clone
CAT＃: SC316255
DLL1 (untagged)-Human delta-like 1 (Drosophila) (DLL1)
CNY 7,952.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Delta; DELTA1; DL1; NEDBAS |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_005618 edited
GAATTCGGCACGAGGGCCCATCGATCCCCCGCGCGTCCGCCGCTGTTCTAAGGAGAGAAG TGGGGGCCCCCCAGGCTCGCGCGTGGAGCGAAGCAGCATGGGCAGTCGGTGCGCGCTGGC CCTGGCGGTGCTCTCGGCCTTGCTGTGTCAGGTCTGGAGCTCTGGGGTGTTCGAACTGAA GCTGCAGGAGTTCGTCAACAAGAAGGGGCTGCTGGGGAACCGCAACTGCTGCCGCGGGGG CGCGGGGCCACCGCCGTGCGCCTGCCGGACCTTCTTCCGCGTGTGCCTCAAGCACTACCA GGCCAGCGTGTCCCCCGAGCCGCCCTGCACCTACGGCAGCGCCGTCACCCCCGTGCTGGG CGTCGACTCCTTCAGTCTGCCCGACGGCGGGGGCGCCGACTCCGCGTTCAGCAACCCCAT CCGCTTCCCCTTCGGCTTCACCTGGCCGGGCACCTTCTCTCTGATTATTGAAGCTCTCCA CACAGATTCTCCTGATGACCTCGCAACAGAAAACCCAGAAAGACTCATCAGCCGCCTGGC CACCCAGAGGCACCTGACGGTGGGCGAGGAGTGGTCCCAGGACCTGCACAGCAGCGGCCG CACGGACCTCAAGTACTCCTACCGCTTCGTGTGTGACGAACACTACTACGGAGAGGGCTG CTCCGTTTTCTGCCGTCCCCGGGACGATGCCTTCGGCCACTTCACCTGTGGGGAGCGTGG GGAGAAAGTGTGCAACCCTGGCTGGAAAGGGCCCTACTGCACAGAGCCGATCTGCCTGCC TGGATGTGATGAGCAGCATGGATTTTGTGACAAACCAGGGGAATGCAAGTGCAGAGTGGG CTGGCAGGGCCGGTACTGTGACGAGTGTATCCGCTATCCAGGCTGTCTCCATGGCACCTG CCAGCAGCCCTGGCAGTGCAACTGCCAGGAAGGCTGGGGGGGCCTTTTCTGCAACCAGGA CCTGAACTACTGCACACACCATAAGCCCTGCAAGAATGGAGCCACCTGCACCAACACGGG CCAGGGGAGCTACACTTGCTCTTGCCGGCCTGGGTACACAGGTGCCACCTGCGAGCTGGG GATTGACGAGTGTGACCCCAGCCCTTGTAAGAACGGAGGGAGCTGCACGGATCTCGAGAA CAGCTACTCCTGTACCTGCCCACCCGGCTTCTACGGCAAAATCTGTGAATTGAGTGCCAT GACCTGTGCGGACGGCCCTTGCTTTAACGGGGGTCGGTGCTCAGACAGCCCCGATGGAGG GTACAGCTGCCGCTGCCCCGTGGGCTACTCCGGCTTCAACTGTGAGAAGAAAATTGACTA CTGCAGCTCTTCACCCTGTTCTAATGGTGCCAAGTGTGTGGACCTCGGTGATGCCTACCT GTGCCGCTGCCAGGCCGGCTTCTCGGGGAGGCACTGTGACGACAACGTGGACGACTGCGC CTCCTCCCCGTGCGCCAACGGGGGCACCTGCCGGGATGGCGTGAACGACTTCTCCTGCAC CTGCCCGCCTGGCTACACAGGCAGGAACTGCAGTGCCCCCGTCAGCAGGTGCGAGCACGC ACCCTGCCACAATGGGGCCACCTGCCACGAGAGGGGCCACCGCTATGTGTGCGAGTGTGC CCGAGGCTACGGGGGTCCCAACTGCCAGTTCCTGCTCCCCGAGCTGCCCCCGGGCCCAGC GGTGGTGGACCTCACTGAGAAGCTAGAGGGCCAGGGCGGGCCATTCCCCTGGGTGGCCGT GTGCGCCGGGGTCATCCTTGTCCTCATGCTGCTGCTGGGCTGTGCCGCTGTGGTGGTCTG CGTCCGGCTGAGGCTGCAGAAGCACCGGCCCCCAGCCGACCCCTGCCGGGGGGAGACGGA GACCATGAACAACCTGGCCAACTGCCAGCGTGAGAAGGACATCTCAGTCAGCATCATCGG GGCCACGCAGATCAAGAACACCAACAAGAAGGCGGACTTCCACGGGGACCACAGCGCCGA CAAGAATGGCTTCAAGGCCCGCTACCCAGCGGTGGACTATAACCTCGTGCAGGACCTCAA GGGTGACGACACCGCCGTCAGGGACGCGCACAGCAAGCGTGACACCAAGTGCCAGCCCCA GGGCTCCTCAGGGGAGGAGAAGGGGACCCCGACCACACTCAGGGGTGGAGAAGCATCTGA AAGAAAAAGGCCGGACTCGGGCTGTTCAACTTCAAAAGACACCAAGTACCAGTCGGTGTA CGTCATATCCGAGGAGAAGGATGAGTGCGTCATAGCAACTGAGGTGTAAAATGGAAGTGA GATGGCAAGACTCCCGTTTCTCTTAAAATAAGTAAAATTCCAAGGATATATGCCCCAACG AATGCTGCTGAAGAGGAGGGAGGCCTCGTGGACTGCTGCTGAGAAACCGAGTTCAGACCG AGCAGGTTCTCCTCCTGAGGTCCTCGACGCCTGCCGACAGCCTGTCGCGGCCCGGCCGCC TGCGGCACTGCCTTCCGTGACGTCGCCGTTGCACTATGGACAGTTGCTCTTAAGAGAATA TATATTTAAATGGGTGAACTGAATTACGCATAAGAAGCATGCACTGCCTGAGTGTATATT TTGGATTCTTATGAGCCAGTCTTTTCTTGAATTAGAAACACAAACACTGCCTTTATTGTC CTTTTTGATACGAAGATGTGCTTTTTCTAGATGGAAAAGATGTGTGTTATTTTTTGGATT |
| Restriction Sites | Please inquire |
| ACCN | NM_005618 |
| Insert Size | 2700 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005618.3, NP_005609.3 |
| RefSeq Size | 3366 bp |
| RefSeq ORF | 2172 bp |
| Locus ID | 28514 |
| UniProt ID | O00548 |
| Domains | DSL, EGF_CA, EGF, EGF |
| Protein Families | Adult stem cells, Cancer stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transmembrane |
| Protein Pathways | Notch signaling pathway |
| Gene Summary | DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
MEDI0639: A Novel Therapeutic Antibody Targeting Dll4 Modulates Endothelial Cell Function and Angiogenesis In Vivo
,David W. Jenkins, Sarah Ross, Margaret Veldman-Jones, Ian N. Foltz, Brandon C. Clavette, Kathy Manchulenko, Cath Eberlein, Jane Kendrew, Philip Petteruti, Song Cho, Melissa Damschroder, Li Peng, Dawn Baker, Neil R. Smith, Hazel M. Weir, David C. Blakey, Vahe Bedian, and Simon T. Barry,
Mol. Cancer Ther., Aug 2012; 11: 1650 - 1660.
[DLL1]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222399 | DLL1 (Myc-DDK-tagged)-Human delta-like 1 (Drosophila) (DLL1) |
CNY 7,944.00 |
|
| RC222399L1 | Lenti ORF clone of Human delta-like 1 (Drosophila) (DLL1), Myc-DDK-tagged |
CNY 10,344.00 |
|
| RC222399L2 | Lenti ORF clone of Human delta-like 1 (Drosophila) (DLL1), mGFP tagged |
CNY 10,344.00 |
|
| RC222399L3 | Lenti ORF clone of Human delta-like 1 (Drosophila) (DLL1), Myc-DDK-tagged |
CNY 10,344.00 |
|
| RC222399L4 | Lenti ORF clone of Human delta-like 1 (Drosophila) (DLL1), mGFP tagged |
CNY 10,344.00 |
|
| RG222399 | DLL1 (tGFP-tagged) - Human delta-like 1 (Drosophila) (DLL1) |
CNY 9,544.00 |
