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MPEG1 (NM_001039396) Human Untagged Clone
CAT＃: SC316021
MPEG1 (untagged)-Human macrophage expressed 1 (MPEG1)
CNY 7,880.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Mpg-1; MPG1; MPS1; P-2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>NCBI ORF sequence for NM_001039396, the custom clone sequence may differ by one or more nucleotides
ATGAACAACTTCAGGGCCACCATCCTCTTCTGGGCAGCGGCAGCATGGGCTAAATCAGGCAAGCCTTCGG GAGAGATGGACGAAGTTGGAGTTCAAAAATGCAAGAATGCCTTGAAACTACCTGTCCTGGAAGTCCTACC TGGAGGGGGCTGGGACAATCTGCGGAATGTGGACATGGGACGAGTTATGGAATTGACTTACTCCAACTGC AGGACAACAGAGGATGGACAGTATATCATCCCTGATGAAATCTTCACCATTCCCCAGAAACAGAGCAACC TGGAGATGAACTCAGAAATCCTGGAATCCTGGGCAAATTACCAGAGTAGCACCTCCTACTCCATCAACAC AGAACTCTCTCTTTTTTCCAAAGTCAATGGCAAGTTTTCCACTGAGTTCCAGAGGATGAAGACCCTCCAA GTGAAGGACCAAGCTATAACTACCCGAGTTCAGGTAAGAAACCTCGTCTACACAGTCAAAATCAACCCAA CTTTAGAGCTAAGCTCAGGTTTTAGGAAGGAACTCCTTGACATCTCTGACCGTCTAGAGAACAACCAGAC GAGGATGGCCACCTACCTGGCAGAACTCCTGGTGCTCAACTATGGCACCCACGTCACCACCAGTGTCGAC GCTGGGGCTGCTCTTATTCAGGAGGACCACCTCAGGGCCTCCTTCCTCCAAGACAGCCAGAGCAGTCGTA GTGCCGTGACCGCCTCTGCTGGACTTGCCTTTCAAAACACCGTGAACTTCAAATTTGAGGAAAACTATAC CTCGCAGAATGTCCTCACCAAGAGCTACCTCTCAAACCGAACCAACTCCAGGGTGCAGAGCATTGGAGGG GTTCCTTTTTACCCAGGCATCACCCTCCAGGCCTGGCAGCAGGGTATCACCAACCACCTGGTGGCCATCG ACCGCTCTGGCCTGCCGCTGCATTTCTTCATCAACCCCAACATGCTACCTGACTTGCCAGGCCCCCTGGT GAAGAAGGTGTCAAAGACAGTGGAAACTGCTGTGAAGCGCTATTATACATTCAACACCTACCCTGGCTGC ACAGATCTCAATTCTCCCAACTTCAATTTTCAGGCCAACACGGATGATGGCTCCTGCGAGGGGAAAATGA CCAACTTCTCTTTCGGTGGGGTTTATCAGGAATGCACTCAGCTCTCAGGGAATAGGGATGTCCTCCTCTG CCAAAAGTTGGAGCAGAAGAATCCACTCACTGGTGATTTCTCCTGCCCCTCTGGCTACTCCCCGGTGCAC CTGTTATCCCAGATCCACGAGGAGGGTTACAACCACCTGGAGTGTCATCGAAAGTGCACTCTCCTCGTCT TCTGCAAGACCGTGTGTGAAGATGTGTTCCAGGTGGCAAAAGCTGAATTTAGGGCTTTTTGGTGTGTGGC CAGCAGCCAAGTACCTGAAAACTCAGGACTGCTTTTTGGGGGCCTCTTCAGCAGCAAGAGCATAAACCCC ATGACAAATGCACAGTCATGCCCAGCCGGCTACTTTCCACTGAGACTCTTTGAAAACCTCAAGGTATGTG TTTCTCAGGACTATGAGTTGGGAAGCAGGTTTGCGGTCCCCTTTGGCGGGTTCTTTAGCTGCACAGTTGG GAACCCCCTGGTAGATCCTGCTATATCCAGAGATTTAGGGGCACCGTCTCTGAAAAAGTGCCCCGGGGGC TTCAGCCAGCACCCAGCCCTCATCAGCGATGGATGCCAAGTGTCCTATTGCGTCAAATCCGGGCTCTTCA CAGGAGGGTCCCTGCCCCCTGCCAGGCTCCCACCTTTCACCCGGCCACCCCTCATGAGTCAGGCTGCCAC CAATACTGTCATAGTGACCAATTCTGAGAATGCGAGATCCTGGATTAAAGACTCCCAGACCCACCAGTGG AGGCTGGGAGAACCGATAGAGCTGCGGAGGGCCATGAATGTCATCCATGGGGATGGTGGTGGTCTGTCAG GAGGGGCTGCAGCTGGGGTCACAGTGGGGGTCACCACCATTCTGGCTGTTGTTATCACCTTGGCCATCTA CGGCACCCGGAAGTTCAAGAAGAAAGCATATCAGGCAATTGAGGAAAGGCAGAGTTTGGTTCCAGGCACT GCAGCAACTGGAGACACCACTTACCAAGAGCAGGGGCAGAGTCCAGCTTAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001039396 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001039396.1, NP_001034485.1 |
| RefSeq Size | 4527 bp |
| RefSeq ORF | 2151 bp |
| Locus ID | 219972 |
| UniProt ID | Q2M385 |
| Protein Families | Transmembrane |
| Gene Summary | Plays a key role in the innate immune response following bacterial infection by inserting into the bacterial surface to form pores (By similarity). By breaching the surface of phagocytosed bacteria, allows antimicrobial effectors to enter the bacterial periplasmic space and degrade bacterial proteins such as superoxide dismutase sodC which contributes to bacterial virulence (By similarity). Shows antibacterial activity against a wide spectrum of Gram-positive, Gram-negative and acid-fast bacteria (PubMed:23753625, PubMed:26402460, PubMed:30609079). Reduces the viability of the intracytosolic pathogen L.monocytogenes by inhibiting acidification of the phagocytic vacuole of host cells which restricts bacterial translocation from the vacuole to the cytosol (By similarity). Required for the antibacterial activity of reactive oxygen species and nitric oxide (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224739 | MPEG1 (Myc-DDK-tagged)-Human macrophage expressed 1 (MPEG1) |
CNY 7,864.00 |
|
| RC224739L1 | Lenti ORF clone of Human macrophage expressed 1 (MPEG1), Myc-DDK-tagged |
CNY 10,264.00 |
|
| RC224739L2 | Lenti ORF clone of Human macrophage expressed 1 (MPEG1), mGFP tagged |
CNY 5,890.00 |
|
| RC224739L3 | Lenti ORF clone of Human macrophage expressed 1 (MPEG1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC224739L4 | Lenti ORF clone of Human macrophage expressed 1 (MPEG1), mGFP tagged |
CNY 10,264.00 |
|
| RG224739 | MPEG1 (tGFP-tagged) - Human macrophage expressed 1 (MPEG1) |
CNY 9,464.00 |
