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JMJD1C (NM_032776) Human Untagged Clone
CAT＃: SC315660
JMJD1C (untagged)-Human jumonji domain containing 1C (JMJD1C), transcript variant 1
CNY 48,930.00
货期*
12周
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | KDM3C; TRIP-8; TRIP8 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_032776, the custom clone sequence may differ by one or more nucleotides
ATGGCGGTAGAGACGCGGGCAGAGCTGGTGGGTAAGCGGTTCCTGTGTGTGGCGGTCGGC GACGAGGCACGTTCGGAGCGCTGGGAGAGCGGACGCGGCTGGCGAAGCTGGCGAGCGGGG GTCATCCGAGCCGTGTCACACAGGGACAGCCGCAATCCGGACCTGGCGGTGTATGTGGAA TTTGATGATCTTGAATGGGATAAACGAGAGTGGGTTAAAGTTTATGAAGATTTTTCAACT TTCTTGGTGGAATACCACTTAATCTGGGCCAAAAGGAATGACCCTAGCCAGACTCAGGGA TCAAAGAGCAAACAGATTCAGTGGCCTGCATTGACTTTCAAACCTCTGGTTGAAAGAAAT ATACCCAGTTCAGTCACTGCAGTAGAATTCCTTGTAGATAAGCAACTGGATTTTTTAACT GAAGATAGTGCCTTTCAGCCCTACCAGGACGACATAGACAGCCTAAACCCAGTTCTCAGG GACAACCCGCAGCTTCATGAGGAAGTGAAAGTCTGGGTAAAGGAACAAAAGGTTCAGGAG ATTTTTATGCAAGGTCCTTATTCCTTAAATGGATACAGAGTGAGAGTATATAGACAAGAC TCTGCCACCCAGTGGTTTACTGGCATAATTACTCATCATGATCTCTTCACCCGCACCATG ATCGTTATGAATGATCAGGTACTAGAACCACAGAATGTCGATCCTTCTATGGTTCAAATG ACCTTTCTAGATGATGTTGTTCACTCTTTGTTAAAAGGTGAAAATATTGGCATTACATCA CGACGCAGGTCTCGTGCCAATCAAAACGTCAACGCTGTTCACAGCCATTATACACGTGCC CAAGCAAATAGTCCCAGACCAGCAATGAACTCCCAAGCTGCTGTACCAAAACAGAATACA CACCAGCAACAGCAACAAAGAAGTATCCGTCCAAATAAGAGGAAGGGCTCAGATAGCAGT ATACCAGATGAAGAGAAGATGAAGGAGGAAAAATATGATTATATATCACGAGGAGAAAAT CCTAAAGGTAAAAACAAACACTTGATGAATAAAAGAAGGAAACCTGAGGAGGATGAAAAG AAACTAAATATGAAAAGACTTCGAACTGACAATGTTTCAGACTTTTCTGAGAGCAGTGAC TCAGAAAATTCAAATAAGAGAATAATAGATAATTCCTCAGAACAGAAGCCAGAGAATGAA TTGAAAAATAAAAATACTTCAAAAATAAATGGAGAAGAAGGAAAACCCCATAATAATGAG AAGGCAGGAGAAGAGACCCTAAAAAATAGCCAGCCTCCCTGGGATCAAATACAGGAAGAT AAAAAACATGAAGAAGCAGAGAAGCGGAAGTCTGTTGACACTCAGCTTCAAGAAGATATG ATTATTCATTCGTCAGAACAGTCCACAGTTTCTGATCATAATTCTAATGATTTACTTCCT CAGGAATGCAATATGGATAAAACACATACCATGGAATTGCTACCAAAGGAGAAGTTTGTA TCCAGACCACCCACACCAAAATGTGTTATTGATATTACAAATGACACTAATTTAGAAAAG GTGGCTCAGGAAAACTCAAGTACCTTTGGCCTTCAGACACTTCAGAAAATGGATCCTAAT GTTAGTGATTCAAAACACTCTATTGCAAATGCAAAATTCTTGGAAACAGCAAAAAAAGAT TCTGACCAGAGCTGGGTCAGTGATGTAGTTAAAGTGGATCTAACCCAATCAAGTGTTACA AATGCTTCTTCAGGAAATGATCACTTGAACATGGAAAAAGAGAAGTATGTCTCTTACATT TCTCCTTTAAGTGCAGTTTCTGTCATGGAAGATAAGCTGCATAAGCGAAGTCCACCTCCA GAGACTATAAAATCTAAACTTAATACTTCAGTAGATACTCACAAGATAAAATCCAGCCCA TCACCTGAAGTTGTTAAACCCAAAATAACTCATTCTCCTGATTCTGTAAAGTCTAAGGCC ACTTATGTGAACAGCCAAGCTACTGGTGAAAGAAGATTGGCAAATAAGATAGAACATGAG CTATCAAGATGCAGTTTTCATCCAATTCCTACTCGAAGCAGTACATTAGAAACTACAAAG AGTCCTCTTATCATTGATAAAAATGAGCATTTTACAGTTTACAGAGATCCTGCACTTATT GGGTCAGAAACAGGAGCTAATCATATTTCACCTTTCCTAAGCCAGCATCCTTTTCCTCTT CACTCCTCATCTCATAGAACCTGTTTAAATCCAGGTACCCATCATCCTGCCTTAACTCCT GCACCCCATTTACTAGCCGGATCATCTAGTCAAACTCCATTACCTACCATTAACACTCAT CCTCTGACTAGTGGTCCACACCATGCTGTTCATCACCCTCATTTACTTCCCACTGTGTTA CCTGGAGTGCCTACTGCCTCCTTACTTGGTGGCCACCCACGACTAGAGAGTGCTCATGCC AGCAGCTTGAGCCACTTAGCGCTAGCACACCAGCAACAACAACAGTTGTTACAGCACCAG TCACCTCATCTTCTTGGACAAGCCCATCCTTCTGCTTCATATAATCAGCTTGGACTTTAT CCAATTATTTGGCAGTATCCAAATGGAACACATGCATACTCAGGACTTGGTTTGCCTTCT TCTAAGTGGGTTCACCCAGAAAATGCAGTTAATGCTGAAGCTTCATTAAGGAGGAATTCT CCCAGTCCTTGGCTACATCAGCCCACCCCTGTGACCTCAGCAGATGGTATTGGATTACTT AGTCACATTCCTGTCAGACCTTCCAGTGCAGAGCCTCATCGGCCTCTTAAAATTACAGCC CATTCCAGTCCACCATTGACAAAAACTTTAGTAGATCATCATAAGGAAGAATTAGAAAGA AAAGCTTTTATGGAACCATTACGGTCTGTTGCATCCACATCAGCCAAAAATGACCTGGAT CTAAATAGGTCACAGACTGGAAAAGATTGTCACTTACATAGGCATTTTGTGGATCCAGTA TTAAATCAGTTACAGAGGCCACCCCAGGAGACTGGAGAGAGGTTAAACAAATACAAAGAG GAACACCGTCGAATTCTTCAAGAAAGTATTGATGTTGCTCCCTTTACAACTAAAATCAAG GGACTTGAGGGTGAGAGAGAGAATTATTCCAGAGTGGCATCATCATCTTCCAGTCCTAAA AGCCATATCATCAAACAAGATATGGATGTAGAACGCTCAGTATCAGATCTTTATAAAATG AAGCACTCAGTGCCTCAGAGTTTACCCCAAAGTAACTATTTCACTACATTGTCTAATAGT GTGGTCAATGAACCACCAAGATCATACCCATCCAAAGAAGTTTCAAATATTTACGGTGAT AAACAGAGTAATGCCCTTGCAGCGGCAGCAGCTAATCCTCAAACTCTGACTTCATTTATA ACATCTCTTTCAAAGCCTCCACCTTTGATTAAACACCAACCAGAAAGTGAAGGTTTAGTA GGCAAGATACCAGAACATCTTCCACATCAGATTGCATCTCACTCAGTAACAACCTTCAGA AATGATTGTAGGAGTCCTACCCATTTGACAGTTTCTTCTACAAATACACTCCGCAGTATG CCTGCATTACATAGAGCACCAGTATTTCACCCACCAATCCATCACAGCCTGGAAAGAAAG GAAGGCAGCTATAGTAGTCTTTCCCCTCCAACTTTAACTCCGGTGATGCCAGTAAATGCT GGTGGTAAAGTTCAAGAATCACAGAAGCCTCCAACTCTAATACCCGAACCAAAAGACTCC CAGGCAAATTTTAAGAGTTCTTCAGAACAGAGTTTGACGGAGATGTGGAGACCTAATAAT AACCTCAGCAAAGAGAAAACTGAATGGCATGTGGAGAAAAGCAGCGGAAAGTTACAGGCT GCTATGGCATCTGTCATTGTGCGTCCATCTTCTAGTACAAAAACTGATAGTATGCCAGCA ATGCAGTTAGCTTCTAAAGATCGAGTTAGTGAAAGATCTTCAGCTGGGGCACATAAAACA GATTGCCTCAAACTAGCAGAAGCCGGAGAAACTGGAAGAATCATTTTGCCAAATGTGAAT TCAGACAGTGTTCACACAAAATCTGAAAAAAACTTTCAGGCTGTCTCACAGGGCAGTGTT CCCAGTTCAGTCATGTCTGCTGTAAATACGATGTGTAATACCAAAACGGATGTAATCACA TCTGCTGCCGATACTACCAGTGTTTCCAGCTGGGGTGGTTCAGAAGTAATTTCCTCTTTA TCAAATACCATTTTGGCCTCTACATCATCAGAATGTGTATCTTCAAAAAGTGTCAGTCAG CCAGTGGCTCAAAAACAAGAATGCAAGGTCAGCACCACAGCACCAGTTACATTAGCCAGT AGTAAGACAGGAAGTGTTGTTCAACCCAGTTCTGGGTTCTCAGGCACAACTGATTTTATC CATTTAAAAAAGCACAAGGCAGCATTGGCTGCAGCTCAGTATAAAAGTAGTAATGCCAGT GAGACTGAACCTAATGCTATAAAAAATCAGACACTTTCAGCCTCCCTTCCTCTGGATAGC ACTGTAATCTGTAGTACAATTAACAAAGCAAACTCTGTAGGAAATGGGCAAGCTTCCCAG ACAAGTCAACCAAACTACCATACTAAACTGAAAAAGGCCTGGCTCACCAGACACTCAGAA GAAGATAAAAATACTAATAAAATGGAAAATTCAGGGAATTCTGTATCAGAAATTATTAAG CCATGTTCTGTCAACTTAATAGCCTCTACATCTAGTGATATACAAAATAGTGTAGATAGT AAGATCATAGTTGATAAATATGTAAAAGATGATAAAGTCAACAGGAGAAAAGCCAAAAGA ACTTATGAATCTGGCTCTGAAAGTGGAGACTCAGATGAAAGTGAAAGCAAGTCAGAGCAA AGGACTAAAAGACAACCTAAGCCAACTTACAAAAAGAAGCAAAATGATTTGCAAAAGAGA AAAGGTGAAATAGAAGAAGATTTGAAACCCAATGGAGTTCTCAGCAGGAGTGCCAAAGAA AGAAGTAAACTGAAGTTGCAAAGCAACAGTAATACTGGCATTCCTCGTTCAGTATTGAAA GATTGGCGTAAAGTCAAGAAGCTGAAGCAAACTGGGGAATCCTTTTTACAGGATGACTCC TGCTGTGAGATAGGGCCTAATTTACAAAAGTGTCGAGAATGTAGACTTATTCGCAGTAAA AAAGGAGAAGAACCAGCTCACTCACCAGTATTTTGTAGATTTTACTACTTTAGACGGTTG TCATTTAGTAAAAACGGAGTAGTTAGAATAGATGGTTTCTCTTCTCCTGACCAATATGAT GATGAAGCTATGAGTTTGTGGACACATGAAAATTTTGAAGATGATGAACTAGATATAGAG ACTTCTAAATATATCTTGGATATAATAGGTGATAAGTTCTGTCAATTAGTAACATCTGAA AAAACAGCTTTGTCCTGGGTGAAAAAGGATGCCAAAATTGCCTGGAAAAGAGCAGTGAGA GGAGTCCGGGAGATGTGTGATGCATGTGAAGCAACATTGTTTAACATTCACTGGGTCTGC CAAAAATGTGGATTTGTGGTCTGCTTAGATTGTTACAAGGCAAAGGAAAGGAAGAGTTCT AGAGATAAAGAACTATATGCTTGGATGAAGTGTGTGAAGGGACAGCCTCATGATCACAAA CATTTAATGCCAACCCAAATTATACCTGGTTCTGTTTTGACAGATCTTCTAGATGCCATG CACACTCTTAGGGAAAAATATGGTATTAAATCCCATTGTCATTGTACTAACAAACAGAAT TTACAAGTTGGAAATTTTCCTACAATGAATGGTGTATCTCAAGTTTTACAGAATGTTCTT AATCACAGTAATAAAATTTCTCTGTGCATGCCTGAGTCTCAGCAGCAAAATACTCCTCCG AAGTCTGAGAAAAATGGTGGCAGCAGCCCAGAGAGTGATGTAGGCACAGATAACAAGTTA ACTCCTCCAGAATCCCAGTCACCACTGCACTGGTTAGCAGATCTTGCAGAGCAAAAAGCC AGAGAGGAAAAAAAAGAAAACAAAGAACTTACCCTTGAAAACCAAATTAAAGAAGAAAGA GAACAAGACAACTCTGAATCTCCAAATGGCAGAACATCACCTCTTGTGTCCCAGAATAAT GAACAAGGCTCAACCTTACGGGATTTGCTGACTACAACAGCTGGAAAGCTACGTGTGGGG TCTACAGATGCTGGCATTGCCTTTGCCCCAGTATATTCAATGGGAGCCCCAAGTAGCAAA AGTGGACGGACTATGCCTAACATTCTTGATGACATAATTGCTTCAGTTGTTGAAAACAAA ATTCCACCAAGTAAAACCTCCAAGATAAATGTAAAACCAGAGCTTAAAGAAGAGCCTGAA GAAAGCATAATATCTGCAGTGGATGAAAATAATAAATTATACAGTGATATACCACATTCT TGGATCTGTGAGAAGCATATTTTATGGCTTAAGGATTATAAGAATAGCAGTAATTGGAAG CTTTTCAAAGAATGTTGGAAACAAGGACAGCCTGCAGTGGTTTCTGGTGTGCATAAGAAA ATGAACATTAGCCTATGGAAGGCGGAATCAATTAGTCTTGATTTTGGAGACCACCAAGCT GATCTCCTGAACTGCAAAGATAGCATCATTTCAAATGCCAATGTTAAGGAATTCTGGGAT GGTTTTGAAGAAGTTTCAAAACGGCAGAAAAACAAGAGTGGAGAAACAGTTGTTTTAAAA TTGAAAGACTGGCCTTCAGGAGAAGACTTCAAGACTATGATGCCAGCAAGATACGAAGAT CTTTTAAAAAGTCTGCCATTGCCAGAATATTGTAATCCAGAAGGAAAATTCAATTTGGCC TCTCATTTGCCAGGATTTTTTGTACGTCCTGATCTAGGACCCAGGTTGTGCAGTGCCTAT GGTGTAGTTGCTGCTAAAGATCATGATATAGGAACAACAAATCTCCATATTGAAGTTTCT GATGTTGTAAATATACTAGTTTATGTTGGCATAGCAAAAGGAAATGGCATTCTCTCAAAA GCAGGAATTCTCAAGAAATTTGAGGAAGAAGATTTGGATGACATTTTAAGGAAAAGATTG AAGGACTCAAGTGAAATACCTGGTGCTCTGTGGCATATTTATGCTGGGAAAGATGTTGAC AAGATAAGGGAATTTCTTCAAAAGATTTCAAAAGAACAAGGCCTTGAAGTTCTACCAGAA CATGATCCAATACGTGACCAAAGTTGGTATGTGAACAAAAAGCTCCGTCAAAGGCTGCTT GAAGAATATGGAGTCAGAACCTGTACTCTTATTCAGTTCCTTGGTGATGCTATTGTTTTG CCAGCGGGAGCACTTCATCAGGTTCAGAATTTTCACAGCTGTATTCAGGTAACTGAAGAT TTTGTGTCTCCAGAACATCTTGTAGAGTCATTTCATTTAACACAGGAACTGAGACTTTTG AAGGAAGAAATCAATTATGATGATAAACTACAGGTTAAAAATATTTTGTATCATGCAGTC AAAGAAATGGTGAGAGCCTTGAAGATACACGAGGATGAAGTAGAGGATATGGAAGAAAAT |
| Restriction Sites | Please inquire |
| ACCN | NM_032776 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_032776.1, NP_116165.1 |
| RefSeq Size | 8762 bp |
| RefSeq ORF | 7623 bp |
| Locus ID | 221037 |
| UniProt ID | Q15652 |
| Protein Families | Druggable Genome |
| Gene Summary | The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). |
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