NRG1 (NM_013961) Human Untagged Clone

CAT#: SC315410

NRG1 (untagged)-Human neuregulin 1 (NRG1), transcript variant GGF



  "NM_013961" in other vectors (6)

CNY 2,400.00

CNY 3,990.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00


NRG1 mouse monoclonal antibody,clone OTI2C3
    • 100 ul

CNY 1,999.00
CNY 3,600.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; NDF; SMDF
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_013961 edited
GGGCTCGCGCGGAGGCCAGGAGCTGAGCGGCGGCGGCTGCCGGACGATGGGAGCGTGAGC
AGGACGGTGATAACCTCTCCCCGATCGGGTTGCGAGGGCGCCGGGCAGAGGCCAGGACGC
GAGCCGCCAGCGGCGGGACCCATCGACGACTTCCCGGGGCGACAGGAGCAGCCCCGAGAG
CCAGGGCGAGCGCCCGTTCCAGGTGGCCGGACCGCCCGCCGCGTCCGCGCCGCGCTCCCT
GCAGGCAACGGGAGACGCCCCCGCGCAGCGCGAGCGCCTCAGCGCGGCCGCTCGCTCTCC
CCATCGAGGGACAAACTTTTCCCAAACCCGATCCGAGCCCTTGGACCAAACTCGCCTGCG
CCGAGAGCCGTCCGCGTAGAGCGCTCCGTCTCCGGCGAGATGTCCGAGCGCAAAGAAGGC
AGAGGCAAAGGGAAGGGCAAGAAGAAGGAGCGAGGCTCCGGCAAGAAGCCGGAGTCCGCG
GCGGGCAGCCAGAGCCCAGCCTTGCCTCCCCAATTGAAAGAGATGAAAAGCCAGGAATCG
GCTGCAGGTTCCAAACTAGTCCTTCGGTGTGAAACCAGTTCTGAATACTCCTCTCTCAGA
TTCAAGTGGTTCAAGAATGGGAATGAATTGAATCGAAAAAACAAACCACAAAATATCAAG
ATACAAAAAAAGCCAGGGAAGTCAGAACTTCGCATTAACAAAGCATCACTGGCTGATTCT
GGAGAGTATATGTGCAAAGTGATCAGCAAATTAGGAAATGACAGTGCCTCTGCCAATATC
ACCATCGTGGAATCAAACGAGATCATCACTGGTATGCCAGCCTCAACTGAAGGAGCATAT
GTGTCTTCAGAGTCTCCCATTAGAATATCAGTATCCACAGAAGGAGCAAATACTTCTTCA
TCTACATCTACATCCACCACTGGGACAAGCCATCTTGTAAAATGTGCGGAGAAGGAGAAA
ACTTTCTGTGTGAATGGAGGGGAGTGCTTCATGGTGAAAGACCTTTCAAACCCCTCGAGA
TACTTGTGCAAGTGCCCAAATGAGTTTACTGGTGATCGCTGCCAAAACTACGTAATGGCC
AGCTTCTACAGTACGTCCACTCCCTTTCTGTCTCTGCCTGAATAG
>OriGene 5' read for NM_013961 unedited
CCGCCCGTCGCGCAACGGGCGGTGGCGCGTACGGCGGGAGGCACATAGCAGAGCCCGCCT
GCGAACGTCAGAACCCCGTATACGACCCACCACAGGGCGGCCGCGAACCCGGCACGAGGG
GCCCGCGCGGAGGCCAGGAGCCGAGCGGCGGCGGCCGCCGGACGATGGGAGCGCGAGCAG
GACGGTGACAACCCCCCCCCGACCGGGCCGCGAGGGCGCCGGGCAGAGGCCAGGACGCGA
GCCGCCAGCGGCGGGACCCATCGACGACTTTCCCGGGGCGACAGGAGCAGCCCCGAGAGC
CAGGGCGAGCGCCCGTTTCCAGGTGGCCGGACCGCCCGCCGCGTCCGCGCCGCGCCCCCT
GCAGGCAACGGGAGACGCCCCCGCGCAGCGCGAGCGCCTCAGCGCGGCCGCTCGCTCTCC
CCATCGAGGGACAAACTTTTCCCAAACCCGATCCGAGCCCTTGGACCAAACTCGCCTGCG
CCGAGAGCCGTCCGCGTAGAGCGCTCCGTCTCCGGCGAGATGTCCGAGCGCAAAGAAGGC
AGAGGCAAAGGGAAGGGCAAGAAGAAGGAGCGAGGCTCCGGCAAGAAGCCGGAGTCCGCG
GCGGGCAGCCAGAGCCCAGCCTTGCCTCCCCAATTGAAAGAGATGAAAAGCCAGGAATCG
GCTGCAGGTTCCAAACTAGTCCTTCGGTGTGAAACCAGTTCTGAATACTCCTCTCTCAGA
TTCAAGTGGTTCAAGAATGGGAATGAATTGAATCGAAAAACAACCACAAATATCAAGATA
CAAAAAAGCCAGGGAAGTCAGACTTCGCATTAACAAAGCATCACTGGCTGATTCTGGAGA
GTATATGTGCAAAGGTGATCAGCAATTAGGAAATGACAGTGCCTCTGCCCA
>OriGene 3' read for NM_013961 unedited
TGGTGCTGCACTTCAGGGCCGGAGAGGCACCTGGGGAGGGGTCACAGGGATGCCACCCGG
GATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGACTATTCAGGCAGAGACAG
AAAGGGAGTGGACGTACTGTAGAAGCTGGCCATTACGTAGTTTTGGCAGCGATCACCAGT
AAACTCATTTGGGCACTTGCACAAGTATCTCGAGGGGTTTGAAAGGTCTTTCACCATGAA
GCACTCCCCTCCATTCACACAGAAAGTTTTCTCCTTCTCCGCACATTTTACAAGATGGCT
TGTCCCAGTGGTGGATGTAGATGTAGATGAAGAAGTATTTGCTCCTTCTGTGGATACTGA
TATTCTAATGGGAGACTCTGAAGACACATATGCTCCTTCAGTTGAGGCTGGCATACCAGT
GATGATCTCGTTTGATTCCACGATGGTGATATTGGCAGAGGCACTGTCATTTCCTAATTT
GCTGATCACTTTGCACATATACTCTCCAGAATCAGCCAGTGATGCTTTGTTAATGCGAAG
TTCTGACTTCCCTGGCTTTTTTTGTATCTTGATATTTTGTGGTTTGTTTTTTCGATTCAA
TTCATTCCCATTCTTGAACCACTTGAATCTGAGAGAGGAGTATTCAGAACTGGTTTCACA
CCGAAGGACTAGTTTGGAACCTGCAGCCGATTCCTGGCTTTTCATCTCTTTCAATTGGGG
AGGCAAGGCTGGGCTCTGGCTGCCCGCCGCGGACTCCGGCTTCTTGCCGGAGCCTCGCTC
CTTCTTCTTGCCCTTCCCTTTGCCTCTGCCTTCTTTGCGCTCGGACATCTCGCCGGAGAC
GGAGCGCTCTACGCGGACGCTCTCGGCGCAGCGAGTTTGGTCCAAGGGCTCGGATCGGGT
TTGGGAAAGTTTGTCCTCGATGGGGAGAGCGAGCGCCGCGCTGAGCGCTCGCGCTGCGCG
GGGGGCGTCTCCGTTGCCTGCAGGAGCGCCGCCGCGAAGCG
Restriction Sites Please inquire     
ACCN NM_013961
Insert Size 1100 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_013961.2, NP_039255.1
RefSeq Size 1703 bp
RefSeq ORF 726 bp
Locus ID 3084
Domains ig, IGc2, IG, EGF, EGF
Protein Families Druggable Genome, Secreted Protein, Transcription Factors, Transmembrane
Protein Pathways ErbB signaling pathway
Gene Summary The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016]
Transcript Variant: The GGF (also called GGFHFB1) variant is identical to HRG-beta3 variant, except for its shorter 5' and 3' UTRs. The GGF and GGF2 variants are expressed in the nervous system and function as a neuronal signal that promotes the proliferation and survival of the oligodendrocyte and the myelinating cells.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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