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TTC3 (NM_003316) Human Untagged Clone
CAT＃: SC315382
TTC3 (untagged)-Human tetratricopeptide repeat domain 3 (TTC3), transcript variant 1
CNY 26,790.00
货期*
4周
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DCRR1; RNF105; TPRDIII |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC315382 representing NM_003316.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGACAATTTTGCTGAGGGAGATTTCACTGTGGCGGATTATGCCTTGTTAGAAGATTGCCCTCACGTG GATGATTGTGTCTTTGCTGCTGAATTTATGAGCAATGATTATGTTCGTGTGACTCAGCTTTACTGTGAT GGGGTGGGTGTGCAATATAAAGATTATATCCAAAGTGAGAGGAATTTGGAATTTGACATCTGCAGTATA TGGTGTAGTAAACCAATTTCTGTCCTGCAAGATTATTGCGATGCCATTAAAATAAACATCTTCTGGCCA CTTCTGTTTCAACATCAAAACAGTTCCGTAATATCACGATTGCATCCCTGTGTGGACGCCAACAATTCA CGTGCTTCTGAGATAAATTTGAAGAAACTACAACATCTTGAGTTGATGGAAGATATTGTGGATTTGGCA AAGAAAGTTGCTAATGATTCATTCCTTATTGGAGGCTTATTGAGAATTGGTTGTAAAATAGAAAATAAA ATCTTGGCAATGGAAGAAGCTCTGAATTGGATAAAATATGCAGGCGATGTAACAATTCTAACTAAATTA GGATCAATTGACAATTGTTGGCCTATGTTAAGTATTTTCTTTACTGAATACAAGTACCACATAACTAAA ATTGTAATGGAAGACTGCAATTTGCTTGAAGAACTTAAAACTCAAAGTTGTATGGATTGTATAGAGGAA GGAGAACTAATGAAAATGAAAGGAAATGAAGAGTTTTCCAAAGAAAGATTTGATATAGCTATTATCTAT TACACCAGAGCCATTGAATATAGACCTGAAAACTACCTTCTTTATGGTAACCGAGCTCTTTGTTTTCTT CGTACTGGACAGTTTAGAAATGCACTCGGTGATGGAAAGAGAGCCACTATTCTGAAGAACACTTGGCCA AAGGGTCATTATCGTTATTGTGATGCTCTTTCTATGCTGGGGGAATATGACTGGGCCCTGCAAGCAAAC ATAAAAGCTCAAAAACTCTGTAAAAATGACCCTGAGGGAATCAAGGATCTAATTCAGCAGCATGTAAAG TTACAAAAACAAATAGAAGACCTACAAGGTCGAACAGCAAATAAGGATCCAATTAAAGCCTTTTATGAA AACAGGGCCTACACACCTAGGAGTTTATCAGCACCTATATTTACTACTTCACTTAACTTTGTGGAGAAG GAAAGAGATTTCAGAAAAATTAATCACGAAATGGCCAACGGTGGTAATCAGAATCTAAAGGTGGCGGAT GAGGCGTTGAAGGTAGATGATTGTGACTGTCATCCTGAATTTTCACCACCATCAAGTCAGCCTCCAAAA CATAAAGGAAAACAAAAATCTCGAAACAATGAATCAGAAAAGTTCAGTTCTAGTTCACCATTGACTTTA CCAGCAGATTTGAAGAACATCTTGGAGAAACAGTTTTCTAAATCTTCCAGAGCTGCACACCAGGATTTT GCTAATATAATGAAAATGCTGAGAAGCTTAATTCAAGATGGCTATATGGCCTTATTGGAGCAGCGTTGC CGCAGCGCTGCACAGGCCTTTACAGAGTTGCTGAACGGTTTAGATCCTCAAAAAATAAAGCAATTGAAC CTGGCCATGATTAACTATGTTTTGGTCGTCTATGGACTTGCCATTTCTCTCCTTGGAATAGGACAGCCT GAGGAATTATCTGAAGCCGAAAACCAGTTTAAGAGGATTATTGAACACTACCCCAGTGAGGGCCTTGAT TGCTTGGCCTACTGTGGAATTGGAAAAGTATATTTGAAAAAAAACAGATTTCTAGAAGCTCTCAATCAC TTTGAGAAAGCAAGAACCTTGATTTATCGTCTTCCTGGAGTGTTAACTTGGCCCACGAGTAATGTGATT ATTGAAGAGTCTCAGCCACAAAAAATAAAGATGCTGTTAGAGAAATTTGTTGAAGAATGCAAGTTCCCT CCAGTGCCAGATGCCATTTGTTGCTATCAGAAGTGCCATGGATATTCTAAGATCCAGATATACATAACT GATCCAGACTTTAAGGGTTTTATACGCATCAGCTGTTGCCAGTACTGTAAAATAGAATTTCACATGAAT TGCTGGAAGAAGTTAAAAACTACAACCTTTAATGATAAAATTGACAAGGATTTTCTACAAGGAATATGT CTTACCCCTGACTGTGAAGGTGTCATTTCTAAGATTATCATCTTCAGCAGTGGTGGTGAAGTTAAATGT GAATTTGAACACAAGGTCATAAAAGAAAAGGTTCCTCCAAGACCTATTCTGAAACAGAAATGTTCTAGC CTAGAGAAACTAAGACTGAAAGAAGACAAAAAATTGAAGAGAAAGATCCAAAAAAAAGAAGCAAAAAAG TTAGCACAAGAAAGAATGGAGGAGGACTTAAGAGAAAGTAATCCACCCAAAAATGAAGAGCAGAAAGAA ACTGTAGACAATGTTCAGCGTTGTCAGTTCCTTGATGACAGAATTCTACAGTGTATAAAGCAGTATGCT GACAAGATTAAATCCGGCATACAGAATACAGCCATGCTTCTCAAAGAATTGCTTTCTTGGAAAGTTTTG AGCACAGAAGACTATACAACCTGTTTTTCTAGCAGAAATTTTCTAAATGAAGCAGTGGACTATGTTATT CGCCACTTGATTCAAGAAAATAACAGAGTAAAGACAAGAATATTTCTGCATGTTTTGAGTGAGCTTAAA GAAGTGGAGCCCAAATTAGCCGCCTGGATCCAAAAACTTAATAGCTTTGGCTTAGATGCCACAGGAACT TTCTTTTCTCGTTATGGAGCATCTCTTAAACTGCTTGATTTTAGTATCATGACTTTCCTCTGGAATGAG AAATATGGTCACAAACTAGACTCTATAGAAGGAAAGCAACTTGATTATTTCTCTGAGCCAGCATCATTG AAGGAAGCCCGTTGTTTAATATGGCTGCTAGAAGAACACAGAGACAAGTTCCCAGCATTGCATAGTGCT TTAGATGAATTCTTTGATATAATGGACAGCCGCTGTACTGTGTTAAGGAAACAAGATAGTGGTGAAGCA CCGTTTAGTTCAACCAAGGTGAAAAACAAAAGCAAGAAAAAGAAGCCAAAGGATTCAAAGCCTATGTTA GTTGGGTCTGGAACAACTTCAGTAACTTCAAATAATGAGATCATCACTTCAAGTGAAGACCATAGCAAT CGAAATTCAGATTCTGCAGGCCCATTTGCAGTGCCTGACCATCTTCGGCAAGATGTAGAAGAATTCGAA GCTCTCTATGACCAACACAGTAACGAATATGTTGTCCGCAATAAGAAGCTATGGGACATGAACCCAAAA CAAAAATGTTCAACTCTATATGATTACTTCTCTCAGTTTTTGGAGGAACATGGTCCCTTGGACATGAGT AACAAGATGTTCTCTGCAGAATATGAGTTTTTCCCAGAAGAAACTCGACAGATACTAGAAAAAGCAGGA GGTTTAAAACCTTTTCTCTTGGGATGCCCTCGTTTTGTTGTGATTGACAACTGTATTGCACTGAAGAAG GTTGCATCACGGCTCAAGAAAAAAAGGAAGAAGAAAAACATTAAAACAAAAGTAGAAGAAATTTCAAAA GCAGGGGAGTATGTACGAGTTAAACTACAACTGAATCCAGCTGCTAGGGAATTTAAACCAGATGTAAAG TCTAAACCAGTGTCAGATTCATCTTCAGCACCAGCTTTTGAAAATGTGAAACCCAAACCTGTGTCTGCA AATTCTCCCAAGCCAGCTTGTGAAGATGTGAAGGCCAAACCAGTATCCGACAATTCTTCTAGACAAGTT TCTGAGGATGGGCAACCCAAAGGGGTCTCTTCTAATTCTCCTAAACCAGGCTCTGAGGATGCAAATTAC AAGCGAGTCTCCTGTAATTCCCCCAAACCGGTTCTTGAGGATGTGAAACCAACTTATTGGGCTCAATCC CATTTGGTCACAGGATACTGTACGTATCTTCCTTTCCAGAGATTTGATATCACCCAGACACCGCCAGCA TACATAAACGTGTTACCAGGTTTGCCCCAGTACACCAGCATATATACACCCTTGGCCAGCCTTTCTCCT GAATATCAGCTACCAAGATCAGTACCAGTGGTGCCGTCTTTTGTAGCCAATGACAGAGCAGATAAAAAT GCTGCTGCCTATTTTGAGGGTCATCATTTGAATGCTGAGAATGTTGCTGGTCACCAGATTGCCTCTGAA ACACAGATCCTTGAGGGCTCTTTGGGAATATCTGTAAAGTCACACTGCAGCACAGGTGATGCTCATACA GTCCTGAGTGAGTCTAACAGAAATGATGAGCACTGTGGAAATTCTAACAACAAATGTGAAGTAATTCCA GAAAGCACCAGTGCAGTAACAAACATTCCACACGTGCAGATGGTTGCCATACAGGTATCTTGGAACATA ATACACCAAGAAGTCAATACTGAGCCATATAATCCTTTTGAGGAACGACAAGGGGAAATTTCACGGATT GAAAAGGAGCACCAAGTATTACAAGACCAACTTCAAGAAGTGTATGAAAATTATGAGCAGATAAAACTT AAGGGCTTAGAAGAGACCAGGGACCTGGAAGAGAAGTTGAAAAGGCACTTAGAAGAAAACAAGATCTCA AAGACGGAATTAGATTGGTTCCTTCAAGATTTGGAAAGAGAAATTAAAAAATGGCAACAGGAAAAAAAA GAAATCCAAGAAAGACTAAAATCACTGAAGAAGAAAATTAAAAAGGTTTCAAATGCCAGTGAAATGTAT ACCCAGAAAAATGATGGAAAGGAAAAGGAACATGAATTACATCTGGATCAGTCCCTTGAAATCAGCAAC ACACTTACAAATGAGAAAATGAAAATAGAAGAGTATATAAAGAAAGGGAAAGAGGATTATGAAGAGAGT CATCAGAGAGCTGTGGCTGCAGAGGTATCCGTACTTGAAAACTGGAAGGAGAGTGAAGTGTATAAGCTA CAGATCATGGAGTCACAAGCAGAAGCCTTTCTGAAGAAGCTGGGGCTGATTAGCCGTGATCCTGCAGCA TATCCTGACATGGAGTCTGATATACGTTCATGGGAATTGTTTCTTTCTAATGTTACAAAAGAAATTGAG AAAGCAAAGTCTCAGTTTGAAGAACAAATTAAGGCAATTAAAAATGGTTCTCGGCTCAGTGAACTTTCT AAAGTGCAGATTTCTGAGCTTTCATTTCCTGCCTGTAACACGGTTCATCCCGAGTTACTCCCTGAGTCT TCAGGCGACGATGGCCAAGGGCTTGTGACTTCTGCAAGCGACGTGACTGGAAACCACGCAGCACTTCAC AGGGATCCTAGTGTGTTCTCTGCTGGTGATTCCCCAGGGGAGGCTCCTTCTGCGCTGTTGCCAGGGCCA CCCCCTGGTCAGCCTGAAGCCACTCAGCTGACAGGGCCAAAACGGGCTGGCCAGGCAGCTCTGTCAGAA CGAAGCCCTGTGGCTGATCGGAAGCAGCCTGTTCCTCCAGGACGTGCTGCGCGTTCAAGCCAGTCTCCA AAAAAGCCGTTCAATAGTATTATTGAGCACCTGTCAGTGGTATTCCCATGTTACAACAGCACTGAGCTT GCTGGTTTTATTAAAAAAGTGCGAAGCAAAAACAAGAACTCACTCTCAGGATTGAGTATTGATGAAATT GTCCAAAGAGTGACAGAACACATTCTAGATGAACAGAAAAAGAAAAAGCCAAACCCAGGAAAGGACAAG AGGACTTATGAGCCCAGCTCTGCCACCCCCGTGACCAGGTCCTCCCAGGGCTCACCCTCGGTGGTTGTT GCACCATCACCCAAAACCAAGGGGCAGAAAGCAGAAGATGTCCCTGTGAGGATTGCACTGGGTGCAAGT TCCTGTGAAATATGCCACGAGGTGTTCAAATCAAAAAACGTGCGTGTGCTCAAATGTGGGCACAAGTAT CACAAAGGGTGCTTTAAGCAGTGGCTTAAAGGGCAGAGCGCTTGCCCGGCCTGCCAGGGTCGTGATCTC CTGACAGAAGAGTCACCTTCTGGAAGAGGCTGGCCCAGTCAGAATCAGGAGCTGCCTTCCTGCTCTTCT AGGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_003316 |
| Insert Size | 6078 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003316.3 |
| RefSeq Size | 9021 bp |
| RefSeq ORF | 6078 bp |
| Locus ID | 7267 |
| UniProt ID | P53804 |
| Domains | TPR, RING |
| Protein Families | Druggable Genome |
| MW | 229.9 kDa |
| Gene Summary | E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation; its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) differs in the 5' UTR and has multiple coding region differences compared to variant 3. These differences cause translation initiation at a downstream AUG and result in an isoform (1) with a shorter N-terminus compared to isoform 3. Variants 1, 2, and 7 all encode the same isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221541 | TTC3 (Myc-DDK-tagged)-Human tetratricopeptide repeat domain 3 (TTC3), transcript variant 1 |
CNY 20,048.00 |
|
| RC221541L1 | Lenti ORF clone of Human tetratricopeptide repeat domain 3 (TTC3), transcript variant 1, Myc-DDK-tagged |
CNY 22,448.00 |
|
| RG221541 | TTC3 (tGFP-tagged) - Human tetratricopeptide repeat domain 3 (TTC3), transcript variant 1 |
CNY 20,900.00 |
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