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SMG7 (NM_201569) Human Untagged Clone
CAT＃: SC315117
SMG7 (untagged)-Human Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG7), transcript variant 4
CNY 10,450.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C1orf16; EST1C; SGA56M |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_201569, the custom clone sequence may differ by one or more nucleotides
ATGCTAGTTACCGATTTGGAATACGCTTTAGACAAGAAAGTAGAACAGGATCTCTGGAAT CACGCCTTTAAGAATCAGATCACAACACTGCAAGGCCAGGCAAAGAATCGAGCAAATCCG AATCGGAGTGAAGTTCAGGCAAACCTTTCTCTGTTCCTAGAGGCAGCTAGTGGCTTCTAT ACTCAGTTATTACAAGAACTGTGTACAGTATTTAATGTAGATTTACCATGCCGTGTGAAG TCTTCCCAATTGGGAATTATCAGCAATAAACAGACGCATACCAGCGCCATAGTGAAGCCA CAGTCTAGCTCCTGTTCCTATATCTGCCAGCACTGCCTCGTCCACCTTGGAGACATTGCT CGATACAGAAACCAGACCAGCCAGGCAGAGTCCTACTATAGGCATGCAGCTCAGCTTGTC CCCTCCAATGGTCAGCCTTATAATCAGTTGGCTATCTTAGCTTCTTCCAAAGGAGACCAT CTGACCACAATTTTCTACTACTGCAGAAGCATTGCTGTGAAGTTCCCTTTCCCAGCTGCC TCCACTAATCTGCAAAAAGCACTTTCTAAAGCACTGGAAAGCCGAGATGAGGTGAAAACC AAGTGGGGTGTTTCTGACTTCATCAAGGCCTTTATTAAATTCCACGGTCATGTGTACCTG AGTAAGAGCTTGGAAAAGTTGAGCCCTCTTCGAGAGAAATTGGAAGAACAGTTTAAGAGG CTGCTATTCCAAAAAGCTTTCAACTCTCAGCAGTTAGTTCATGTCACTGTCATTAACCTG TTTCAACTTCATCACCTTCGTGACTTTAGCAATGAAACCGAGCAGCACACTTATAGCCAA GATGAGCAGCTATGTTGGACACAGTTGCTGGCCCTCTTTATGTCTTTTCTTGGCATCCTG TGCAAGTGTCCTCTACAGAATGAGTCTCAGGAGGAGTCCTACAATGCCTATCCTCTTCCA GCAGTCAAGGTCTCCATGGACTGGCTAAGACTCAGACCCAGGGTCTTTCAGGAGGCAGTG GTGGATGAAAGACAGTACATTTGGCCCTGGTTGATTTCTCTTCTGAATAGTTTCCATCCC CATGAAGAGGACCTCTCAAGTATTAGTGCGACACCACTTCCAGAGGAGTTTGAATTACAA GGATTTTTGGCATTGAGACCTTCTTTCAGGAACTTGGATTTTTCCAAAGGTCACCAGGGT ATTACAGGGGACAAAGAAGGCCAGCAACGACGAATACGACAGCAACGCTTGATCTCTATA GGCAAATGGATTGCTGATAATCAGCCAAGGCTGATTCAGTGTGAAAATGAGGTAGGGAAA TTGTTGTTTATCACAGAAATCCCAGAATTAATACTGGAAGACCCCAGTGAAGCCAAAGAG AACCTCATTCTGCAAGAAACATCTGTGATAGAGTCGCTGGCTGCAGATGGGAGCCCAGGG CTAAAATCAGTGCTATCTACAAGCCGAAATTTAAGCAACAACTGTGACACAGGAGAGAAG CCAGTGGTTACCTTCAAAGAAAACATTAAGACACGAGAAGTGAACAGAGACCAAGGAAGA AGTTTTCCTCCCAAAGAGGTAAAATCCCAGACAGAACTAAGAAAGACTCCAGTGTCTGAA GCCAGAAAAACACCTGTAACTCAAACCCCAACTCAAGCAAGTAACTCCCAGTTCATCCCC ATTCATCACCCTGGAGCCTTCCCTCCTCTTCCCAGCAGGCCAGGGTTTCCGCCCCCAACA TATGTTATCCCCCCGCCTGTGGCATTTTCTATGGGCTCAGGTTACACCTTCCCAGCTGGT GTTTCTGTCCCAGGAACCTTTCTTCAGCCTACAGCTCACTCTCCAGCAGGAAACCAGGTG CAAGCTGGGAAACAGTCCCACATTCCTTACAGCCAGCAACGGCCCTCTGGACCAGGGCCA ATGAACCAGGGACCTCAACAATCACAGCCACCTTCCCAGCAACCCCTTACATCTTTACCA GCTCAGCCAACAGCACAGTCTACAAGCCAGCTGCAGGTTCAAGCTCTAACTCAGCAACAA CAATCCCCTACAAAAGCTGTGCCGGCTTTGGGGAAAAGCCCGCCTCACCACTCTGGATTC CAGCAGTATCAACAGGCAGATGCCTCCAAACAGCTGTGGAATCCCCCTCAGGTTCAAGGC CCATTAGGGAAAATTATGCCTGTGAAACAGCCCTACTACCTTCAGACCCAAGACCCCATA AAACTGTTTGAGCCGTCATTGCAACCTCCTGTAATGCAGCAGCAGCCTCTAGAAAAAAAA ATGAAGCCTTTTCCCATGGAGCCATATAACCATAATCCCTCAGAAGTCAAGGTCCCAGAA TTCTACTGGGATTCTTCCTACAGCATGGCTGATAACAGATCTGTAATGGCACAGCAAGCA AACATAGACCGCAGGGGCAAACGGTCACCAGGAGTCTTCCGTCCAGAGCAGGATCCTGTA CCCAGAATGCCGTTTGAGAAATCCTTATTGGAGAAGCCCTCAGAGCTCATGTCACATTCA TCCTCTTTCCTGTCCCTCACCGGATTCTCTCTCAATCAGGAAAGATACCCAAATAATAGT ATGTTCAATGAGGTATATGGGAAAAACCTGACATCCAGCTCCAAAGCAGAACTCAGTCCC TCAATGGCCCCCCAGGAAACATCTCTGTATTCCCTTTTTGAAGGGACTCCGTGGTCTCCA TCACTTCCTGCCAGTTCAGATCATTCAACACCAGCCAGCCAGTCTCCTCATTCCTCTAAC CCAAGCAGCCTACCCAGCTCTCCTCCAACACACAACCATAATTCTGTTCCATTCTCCAAT TTTGGACCCATTGGGACTCCAGATAACAGGGATAGAAGGACTGCAGATCGGTGGAAAACT GATAAGCCAGCCATGGGTGGGTTTGGCATTGATTATCTCTCAGCAACGTCATCCTCTGAG AGCAGTTGGCATCAGGCCAGCACTCCGAGTGGCACCTGGACAGGCCATGGCCCTTCCATG GAGGATTCCTCTGCTGTCCTCATGGAAAGCCTAAAGTCTATCTGGTCCAGTTCCATGATG CATCCTGGACCTTCTGCTCTGGAGCAGCTGTTAATGCAGCAGAAGCAGAAACAGCAACGG GGACAAGGCACCATGAACCCTCCACAC |
| Restriction Sites | Please inquire |
| ACCN | NM_201569 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_201569.1, NP_963863.1 |
| RefSeq Size | 5676 bp |
| RefSeq ORF | 3150 bp |
| Locus ID | 9887 |
| UniProt ID | Q92540 |
| Gene Summary | This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011] Transcript Variant: This variant (4) has multiple differences in the coding region compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 4) has a distinct C-terminus and is longer than isoform 1. |
Documents
| Product Manuals |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220801 | SMG7 (Myc-DDK-tagged)-Human Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG7), transcript variant 4 |
CNY 11,780.00 |
|
| RC220801L3 | Lenti-ORF clone of SMG7 (Myc-DDK-tagged)-Human Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG7), transcript variant 4 |
CNY 13,680.00 |
|
| RC220801L4 | Lenti-ORF clone of SMG7 (mGFP-tagged)-Human Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG7), transcript variant 4 |
CNY 13,680.00 |
|
| RG220801 | SMG7 (tGFP-tagged) - Human Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG7), transcript variant 4 |
CNY 12,920.00 |
