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THRAP3 (NM_005119) Human Untagged Clone
CAT＃: SC314985
THRAP3 (untagged)-Human thyroid hormone receptor associated protein 3 (THRAP3)
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BCLAF2; TRAP150 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC314985 representing NM_005119.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGTCAAAAACAAACAAATCCAAGTCTGGATCTCGCTCTTCTCGCTCAAGATCTGCATCAAGATCTCGT TCTCGTTCATTTTCGAAGTCTCGGTCCCGAAGCCGATCTCTCTCTCGTTCAAGGAAGCGCAGGCTGAGT TCTAGGTCTCGTTCCAGATCATATTCTCCAGCTCATAACAGAGAAAGAAACCACCCAAGAGTATATCAG AATCGGGATTTCCGAGGTCACAACAGAGGCTATAGAAGGCCCTATTATTTCCGTGGGCGTAACAGAGGC TTTTATCCATGGGGCCAATATAACCGAGGAGGCTATGGAAACTACCGCTCAAATTGGCAGAATTACCGG CAAGCATACAGTCCTCGTCGAGGCCGTTCAAGATCCCGGTCCCCAAAGAGAAGGTCCCCTTCACCAAGG TCCAGGAGCCATTCTAGAAACTCTGATAAGTCGTCTTCTGACCGGTCAAGGCGCTCCTCATCCTCCCGT TCTTCCTCCAACCATAGCCGAGTTGAATCTTCTAAGCGCAAGTCTGCAAAGGAGAAAAAGTCCTCTTCT AAGGATAGCCGGCCATCTCAGGCTGCCGGGGATAACCAGGGAGATGAGGCCAAGGAGCAGACATTCTCT GGAGGCACCTCTCAAGATACAAAAGCATCTGAGAGCTCGAAGCCATGGCCAGATGCCACCTACGGCACT GGTTCTGCATCACGGGCCTCAGCAGTTTCTGAGCTGAGTCCTCGGGAGCGAAGCCCAGCTCTCAAAAGC CCCCTCCAGTCTGTGGTGGTGAGGCGGCGGTCACCCCGTCCTAGCCCCGTGCCAAAACCTAGTCCTCCA CTTTCCAGCACATCCCAGATGGGCTCAACTCTGCCGAGTGGTGCCGGGTATCAGTCTGGGACACACCAA GGTCAGTTCGACCATGGTTCTGGGTCCCTGAGTCCATCCAAAAAGAGCCCTGTGGGTAAGAGTCCACCA TCCACTGGCTCCACATATGGCTCATCTCAGAAGGAGGAGAGTGCTGCTTCAGGAGGAGCAGCCTATACA AAGAGGTATCTAGAAGAGCAGAAGACAGAGAATGGAAAAGATAAGGAACAGAAACAAACAAATACCGAT AAAGAAAAAATAAAAGAGAAAGGGAGCTTCTCTGACACAGGCTTGGGTGATGGAAAAATGAAATCTGAT TCTTTTGCTCCCAAAACTGATTCTGAGAAGCCTTTTCGGGGCAGTCAGTCTCCCAAAAGGTATAAGCTC CGAGATGACTTTGAGAAGAAGATGGCTGACTTCCACAAGGAGGAGATGGATGATCAAGATAAGGACAAA GCTAAGGGAAGAAAGGAATCTGAGTTTGATGATGAACCCAAATTTATGTCTAAAGTCATAGGTGCAAAC AAAAACCAGGAGGAGGAGAAGTCAGGCAAATGGGAGGGCCTGGTATATGCACCTCCAGGGAAGGAAAAG CAGAGAAAAACAGAGGAGCTGGAGGAGGAGTCTTTCCCAGAGAGATCCAAAAAGGAAGATCGGGGCAAG AGAAGCGAAGGTGGGCACAGGGGCTTTGTGCCTGAGAAGAATTTCCGAGTGACTGCTTATAAAGCAGTC CAGGAGAAAAGCTCATCACCTCCCCCAAGAAAGACCTCTGAGAGCCGAGACAAGCTGGGAGCGAAAGGA GATTTTCCCACAGGAAAGTCTTCCTTTTCCATTACTCGAGAGGCACAGGTCAATGTCCGGATGGACTCT TTTGATGAGGACCTCGCACGACCCAGTGGCTTATTGGCTCAGGAACGCAAGCTTTGCCGAGATCTAGTC CATAGCAACAAAAAGGAACAGGAGTTTCGTTCCATTTTCCAGCACATACAATCAGCTCAGTCTCAGCGT AGCCCCTCAGAACTGTTTGCCCAACATATAGTGACCATTGTTCACCATGTTAAAGAGCATCACTTTGGG TCCTCAGGAATGACATTACATGAACGCTTTACTAAATACCTAAAGAGAGGAACTGAGCAGGAGGCAGCC AAAAACAAGAAAAGCCCAGAGATACACAGGAGAATAGACATTTCCCCCAGTACATTCAGAAAACATGGT TTGGCTCATGATGAAATGAAAAGTCCCCGGGAACCTGGCTACAAGGCTGAGGGAAAATACAAAGATGAT CCTGTTGATCTCCGCCTTGATATTGAACGTCGTAAAAAACATAAGGAGAGAGATCTTAAACGAGGTAAA TCGAGAGAATCAGTGGATTCCCGAGACTCCAGTCACTCAAGGGAAAGGTCAGCTGAAAAAACAGAGAAA ACTCATAAAGGATCAAAGAAACAGAAGAAGCATCGGAGAGCAAGAGACAGGTCCAGATCCTCCTCCTCT TCCTCCCAGTCATCTCACTCCTACAAAGCAGAAGAGTACACTGAAGAGACAGAGGAAAGAGAGGAGAGC ACCACGGGCTTTGACAAATCAAGACTGGGGACCAAAGACTTTGTGGGTCCAAGTGAAAGAGGAGGTGGC AGAGCTCGAGGAACCTTTCAGTTTCGAGCCAGAGGAAGAGGCTGGGGCAGAGGCAACTACTCTGGGAAC AATAACAACAACAGCAACAACGATTTTCAAAAAAGAAACCGGGAAGAGGAGTGGGACCCAGAGTACACA CCCAAAAGCAAGAAGTATTACTTGCATGATGACCGTGAAGGCGAAGGCAGTGACAAGTGGGTGAGCCGG GGCCGGGGCCGAGGAGCCTTTCCTCGGGGTCGGGGCCGGTTCATGTTCCGGAAATCAAGTACCAGCCCC AAGTGGGCCCATGACAAGTTCAGTGGGGAGGAAGGGGAGATTGAAGACGACGAGAGTGGGACAGAGAAC CGAGAAGAGAAGGACAATATACAGCCCACAACCGAGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_005119 |
| Insert Size | 2868 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005119.3 |
| RefSeq Size | 4447 bp |
| RefSeq ORF | 2868 bp |
| Locus ID | 9967 |
| UniProt ID | Q9Y2W1 |
| Protein Families | Druggable Genome, Transcription Factors |
| MW | 108.7 kDa |
| Gene Summary | Involved in pre-mRNA splicing. Remains associated with spliced mRNA after splicing which probably involves interactions with the exon junction complex (EJC). Can trigger mRNA decay which seems to be independent of nonsense-mediated decay involving premature stop codons (PTC) recognition. May be involved in nuclear mRNA decay. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC/CD45 is proposed to sequester phosphorylated SFPQ from PTPRC/CD45 pre-mRNA in resting T-cells. Involved in cyclin-D1/CCND1 mRNA stability probably by acting as component of the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. Involved in response to DNA damage. Is excluced from DNA damage sites in a manner that parallels transcription inhibition; the function may involve the SNARP complex. Initially thought to play a role in transcriptional coactivation through its association with the TRAP complex; however, it is not regarded as a stable Mediator complex subunit. Cooperatively with HELZ2, enhances the transcriptional activation mediated by PPARG, maybe through the stabilization of the PPARG binding to DNA in presence of ligand. May play a role in the terminal stage of adipocyte differentiation. Plays a role in the positive regulation of the circadian clock. Acts as a coactivator of the CLOCK-ARNTL/BMAL1 heterodimer and promotes its transcriptional activator activity and binding to circadian target genes (PubMed:24043798).[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213342 | THRAP3 (Myc-DDK-tagged)-Human thyroid hormone receptor associated protein 3 (THRAP3) |
CNY 6,992.00 |
|
| RC213342L1 | Lenti ORF clone of Human thyroid hormone receptor associated protein 3 (THRAP3), Myc-DDK-tagged |
CNY 9,392.00 |
|
| RC213342L2 | Lenti ORF clone of Human thyroid hormone receptor associated protein 3 (THRAP3), mGFP tagged |
CNY 9,030.00 |
|
| RC213342L3 | Lenti ORF clone of Human thyroid hormone receptor associated protein 3 (THRAP3), Myc-DDK-tagged |
CNY 9,392.00 |
|
| RC213342L4 | Lenti ORF clone of Human thyroid hormone receptor associated protein 3 (THRAP3), mGFP tagged |
CNY 9,392.00 |
|
| RG213342 | THRAP3 (tGFP-tagged) - Human thyroid hormone receptor associated protein 3 (THRAP3) |
CNY 8,592.00 |
