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STIM2 (NM_020860) Human Untagged Clone
CAT＃: SC314792
STIM2 (untagged)-Human stromal interaction molecule 2 (STIM2), transcript variant 2
CNY 6,112.00
| Cited in 5 publications. |
Product images
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_020860 edited
GGGGGATGCGCCGCGGCGGCGGCGGCGCGGGAGCTGGGGTTGGTGTTTGGCGGCGCCAGA GCAGCGGATCCCGGTCTCGCCGCAGCAGCAGCGCGGGTGTCGTGCACCGCCTGAAGACGC CGTACCTTTCTACCCCCCACCTTTTTTTTTTTTTTTTTTTAAATAACCGGAACCAATGAA CGCAGCCGGGATCAGAGCTCCGGAGGCCGCCGGTGCCGATGGGACCAGGCTGGCGCCCGG CGGGAGCCCGTGTCTGAGGCGGCGGGGGCGGCCGGAGGAGTCGCCGGCGGCGGTGGTGGC GCCTCGCGGAGCCGGCGAGCTGCAGGCGGCCGGGGCGCCGCTGCGCTTTCACCCGGCTTC TCCTCGGCGCCTTCATCCCGCCTCGACTCCTGGCCCAGCGTGGGGCTGGCTGCTGCGGCG GCGGCGCTGGGCTGCGTTGCTGGTGCTCGGGCTGCTGGTAGCCGGAGCGGCGGACGGATG CGAGCTTGTGCCCCGGCACCTCCGCGGGCGGCGGGCGACTGGCTCTGCCGCAACTGCCGC CTCCTCTCCCGCCGCGGCGGCCGGCGATAGCCCGGCGCTCATGACAGATCCCTGCATGTC ACTGAGTCCACCATGCTTTACAGAAGAAGACAGATTTAGTCTGGAAGCTCTTCAAACAAT ACATAAACAAATGGATGATGACAAAGATGGTGGAATTGAAGTAGAGGAAAGTGATGAATT CATCAGAGAAGATATGAAATATAAAGATGCTACTAATAAACACAGCCATCTGCACAGAGA AGATAAACATATAACGATTGAGGATTTATGGAAACGATGGAAAACATCAGAAGTTCATAA TTGGACCCTTGAAGACACTCTTCAGTGGTTGATAGAGTTTGTTGAACTACCCCAATATGA GAAGAATTTTAGAGACAACAATGTCAAAGGAACGACACTTCCCAGGATAGCAGTGCACGA ACCTTCATTTATGATCTCCCAGTTGAAAATCAGTGACCGGAGTCACAGACAAAAACTTCA GCTCAAGGCATTGGATGTGGTTTTGTTTGGACCTCTAACACGCCCACCTCATAACTGGAT GAAAGATTTTATCCTCACAGTTTCTATAGTAATTGGTGTTGGAGGCTGCTGGTTTGCTTA TACGCAGAATAAGACATCAAAAGAACATGTTGCAAAAATGATGAAAGATTTAGAGAGCTT ACAAACTGCAGAGCAAAGTCTAATGGACTTACAAGAGAGGCTTGAAAAGGCACAGGAAGA AAACAGAAATGTTGCTGTAGAAAAGCAAAATTTAGAGCGCAAAATGATGGATGAAATCAA TTATGCAAAGGAGGAGGCTTGTCGGCTGAGAGAGCTAAGGGAGGGAGCTGAATGTGAATT GAGTAGACGTCAGTATGCAGAACAGGAATTGGAACAGGTTCGCATGGCTCTGAAAAAGGC CGAAAAAGAATTTGAACTGAGAAGCAGTTGGTCTGTTCCAGATGCACTTCAGAAATGGCT TCAGTTAACACATGAAGTAGAAGTGCAATACTACAATATTAAAAGACAAAACGCTGAAAT GCAGCTAGCTATTGCTAAAGATGAGGCAGAAAAAATTAAAAAGAAGAGAAGCACAGTCTT TGGGACTCTGCACGTTGCACACAGCTCCTCCCTAGATGAGGTAGACCACAAAATTCTGGA AGCAAAGAAAGCTCTCTCTGAGTTGACAACTTGTTTACGAGAACGACTTTTTCGCTGGCA ACAAATTGAGAAGATCTGTGGCTTTCAGATAGCCCATAACTCAGGACTCCCCAGCCTGAC CTCTTCCCTTTATTCTGATCACAGCTGGGTGGTGATGCCCAGAGTCTCCATTCCACCCTA TCCAATTGCTGGAGGAGTTGATGACTTAGATGAAGACACACCCCCAATAGTGTCACAATT TCCCGGGACCATGGCTAAACCTCCTGGATCATTAGCCAGAAGCAGCAGCCTGTGCCGTTC ACGCCGCAGCATTGTGCCGTCCTCGCCTCAGCCTCAGCGAGCTCAGCTTGCTCCACACGC CCCCCACCCGTCACACCCTCGGCACCCTCACCACCCGCAACACACACCACACTCCTTGCC TTCCCCTGATCCAGATATCCTCTCAGTGTCAAGTTGCCCTGCGCTTTATCGAAATGAAGA GGAGGAAGAGGCCATTTACTTCTCTGCTGAAAAGCAATGGGAAGTGCCAGACACAGCTTC AGAATGTGACTCCTTAAATTCTTCCATTGGAAGGAAACAGTCTCCTCCTTTAAGCCTCGA GATATACCAAACATTATCTCCGCGAAAGATATCAAGAGATGAGGTGTCCCTAGAGGATTC CTCCCGAGGGGATTCGCCTGTAACTGTGGATGTGTCTTGGGGTTCTCCCGACTGTGTAGG TCTGACAGAAACTAAGAGTATGATCTTCAGTCCTGCAAGCAAAGTGTACAATGGCATTTT GGAGAAATCCTGTAGCATGAACCAGCTTTCCAGTGGCATCCCGGTGCCTAAACCTCGCCA CACATCATGTTCCTCAGCTGGCAACGACAGTAAACCAGTTCAGGAAGCCCCAAGTGTTGC CAGAATAAGCAGCATCCCACATGACCTTTGTCATAATGGAGAGAAAAGCAAAAAGCCATC AAAAATCAAAAGCCTTTTTAAGAAGAAATCTAAGTGAACTGGCTGACTTGATGGAATCAT GTTCAAGTGGCATCTGTAAACTATTATCCCCCACCCTCCACTCCCCACCTTTTTTTTGGT TTAATTTTAGGAATGTAACTCCATTGGGGCTTTCCAGGCCGGATGCCATAGTGGAACATC CAGAAGGGCAACTGTCTACTGTCTGCTTATTTAAGTGACTATATATAATCAATTCATCAA GCCAGTTATTACTGAAAAATCATTGAAATGAGACAGTTTACAGTCATTTCTGCCTATTTA TTTCTGCTTTGTTCTCAGTGATGTATATGCAACATTTTGTTGAAAGCCACGATGGACTTA CAAGCTTTAATGGACTCGTAAGCCAGCATGGGCTTGCAAAAATTTCTTGTTTACCAGAGC ATCTTCTTATCTTTCCACAGAGCTATTTACATCCTGGACTATATAACTTAAAAGAAGTAA AACGTAATTGCACTACTGTTTTCCAGACTGGAAAAAAAAAAAAATCTCTGCAAGTGAAAC TGTATAGAGTTTATAAAATGACTATGGATAGGGGACTGTTTTCACTTTTAGATCAAAATG GGTTTTTAAGTAGAACCTAGGGTTTCTAATTGACTTGATTTCTGGAAATGAAAACCCGCG CTTTTATTATGGGAAGCTTCTTGAACTGCATTTACTATTGTGAAGTTTCAAGTCCCGCTG TAAAGATCATGTTGTTTTGTTTTCCCCAGGGCTTTCACTGTGATTTACTGCATTGCAGGC TGTATGATAAAACACACATAATTTAAAGAGAGAAGGCTCTTGATTCCTTATGCAAGTGGA AGAGTTGAAACTTGATTGAAGGACTTAAAACATTCACAACCTTAAGCCGAGGTGGGGGGA TATGGGGATTCAGGCAATTGTTTACACACTTTGAATAACTGCAAAGGATTTACGGTTTGT GAAAAATGTGTACTGTGGAAAAGATAATAAATTGAAGACATTATTGTGTGGGATTGTGCT GATTTTTGTTGATAACACAAAAAACACTATGTTTTCTGGAGAGCTGTGTAAGCTGTCTTG TTGCTTAGTTGCAATATAAGAAATAGTGATGTTTTGGACGTAAGTTGTCAACAAATTTCT ATTTTATATTGTTATATTTTTATGTAGTTTGAAATGTAAAAATGTTCTAATATCAAGATT AACAAATATAAATTTATGGTGCATTTAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_020860 unedited
GGGATTTGTATACGACTCCTATAGGGCGGCCGCGAAATCGGCACGAGGGGGGGATGCGCC GCGGCGGCGGCGGCGCGGGAGCTGGGGTTGGTGTTTGGCGGCGCCAGAGCAGCGGATCCC GGTCTCGCCGCAGCAGCAGCGCGGGTGTCGTGCACCGCCTGAAGACGCCGTACCTTTCTA CCCCCCACCTTTTTTTTTTTTTTTTTTTAAATAACCGGAACCAATGAACGCAGCCGGGAT CAGAGCTCCGGAGGCCGCCGGTGCCGATGGGACCAGGCTGGCGCCCGGCGGGAGCCCGTG TCTGAGGCGGCGGGGGCGGCCGGAGGAGTCGCCGGCGGCGGTGGTGGCGCCTCGCGGAGC CGGCGAGCTGCAGGCGGCCGGGGCGCCGCTGCGCTTTCACCCGGCTTCTCCTCGGCGCCT TCATCCCGCCTCGACTCCTGGCCCAGCGTGGGGCTGGCTGCTGCGGCGGCGGCGCTGGGC TGCGTTGCTGGTGCTCGGGCTGCTGGTAGCCGGAGCGGCGGACGGATGCGAGCTTGTGCC CCGGCACCTCCGCGGGCGGCGGGCGACTGGCTCTGCCGCAACTGCCGCCTCCTCTCCCGC CGCGGCGGCCGGCGATAGCCCGGCGCTCATGACAGATCCCTGCATGTCACTGAGTCCACC ATGCTTTACAGAAGAAGACAGATTTAGTCTGGAAGCTCTTCAAACAATACATAAACAAAT GGATGATGACAAAGATGGTGGAATTGAAGTAGAGGAAAGTGATGAATTCATCAGAGAAGA TATGAAATATAAAGATGCTACTAATAAACACAGCCATCTGCACAGAGAGATAAACATATA ACGATTGAGATTTATGGGAACGATGGAAAACATCAGAAGTCATAATTGGACCCTTGAAGA CACTCTTCAGTGGTTGAATAGAGTTGTTGAACTACCCCAAT >OriGene 3' read for NM_020860 unedited
TGACGATGCACTTCCGGGCCGGAGAGCACTGGGGAGGGGTACAGGGATGCCCCCGGGATC TGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTT TTAAATGCACCATAAATTTATATTTGTTAATCTTGATATTAGAACATTTTTACATTTCAA ACTACATAAAAATATAACAATATAAAATAGAAATTTGTTGACAACTTACGTCCAAAACAT CACTATTTCTTATATTGCAACTAAGCAACAAGACAGCTTACACAGCTCTCCAGAAAACAT AGTGTTTTTTGTGTTATCAACAAAAATCAGCACAATCCCACACAATAATGTCTTCAATTT ATTATCTTTTCCACAGTACACATTTTTCACAAACCGTAAATCCTTTGCAGTTATTCAAAG TGTGTAAACAATTGCCTGAATCCCCATATCCCCCCACCTCGGCTTAAGGTTGTGAATGTT TTAAGTCCTTCAATCAAGTTTCAACTCTTCCACTTGCATAAGGAATCAAGAGCCTTCTCT CTTTAAATTATGTGTGTTTTATCATACAGCCTGCAATGCAGTAAATCACAGTGAAAGCCC TGGGGAAAACAAAACAACATGATCTTTACAGCGGGACTTGAAACTTCACAATAGTAAATG CAGTTCAAGAAGCTTCCCATAATAAAAGCGCGGGTTTTCATTTCCAGAAATCAAGTCAAT TAGAAACCCTAGGTTCTACTTAAAAACCCATTTTGATCTAAAAGTGAAAACAGTCCCCTA TCCATAGTCATTTTATAAACTCTATACAGTTTCACTTGCAGAGATTTTTTTTTTTCCAGT CTGAAACAGTAGTGCATTACGTTTTACTTCTTTAGTATATAGTCCAGGATGTAAATAGCT CTGTGGGAGATAGGA |
| Restriction Sites | Please inquire |
| ACCN | NM_020860 |
| Insert Size | 3900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_020860.1, NP_065911.2 |
| RefSeq Size | 5156 bp |
| RefSeq ORF | 2502 bp |
| Locus ID | 57620 |
| UniProt ID | Q9P246 |
| Gene Summary | This gene is a member of the stromal interaction molecule (STIM) family and likely arose, along with related family member STIM1, from a common ancestral gene. The encoded protein functions to regulate calcium concentrations in the cytosol and endoplasmic reticulum, and is involved in the activation of plasma membrane Orai Ca(2+) entry channels. This gene initiates translation from a non-AUG (UUG) start site. A signal peptide is cleaved from the resulting protein. Multiple transcript variants result from alternative splicing. [provided by RefSeq, Dec 2009] Transcript Variant: This variant (2, also known as STIM2.2 or STIM2alpha) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1. This isoform functions as a positive regulator of store-operated calcium entry (SOCE). |
Citations (5)
| The use of this cDNA Clones has been cited in the following citations: |
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Polyamines regulate intestinal epithelial restitution through TRPC1-mediated Ca2+ signaling by differentially modulating STIM1 and STIM2
,Jaladanki N. Rao, Navneeta Rathor, Ran Zhuang, Tongtong Zou, Lan Liu, Lan Xiao, Douglas J. Turner, and Jian-Ying Wang,
Am J Physiol Cell Physiol, Aug 2012; 303: C308 - C317.
[STIM2]
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TRPC channels function independently of STIM1 and Orai1
,Wayne I. DeHaven, Bertina F. Jones, John G. Petranka, Jeremy T. Smyth, Takuro Tomita, Gary S. Bird, and James W. Putney, Jr,
J. Physiol., May 2009; 587: 2275 - 2298.
[STIM2]
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Store-operated cyclic AMP signalling mediated by STIM1
,Konstantinos Lefkimmiatis, Meera Srikanthan, Isabella Maiellaro, Mary Pat Moyer, Silvana Curci, Aldebaran M. Hofer,
Nature Cell Biology 11, 433-442 (15 March 2009)
[STIM2]
|
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Stromal Interaction Molecule (STIM) 1 and STIM2 Calcium Sensing Regions Exhibit Distinct Unfolding and Oligomerization Kinetics
,Peter B. Stathopulos, Le Zheng, and Mitsuhiko Ikura,
J. Biol. Chem., Jan 2009; 284: 728 - 732.
[STIM2]
|
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Role of the Store-operated Calcium Entry Proteins, Stim1 and Orai1, in Muscarinic-Cholinergic Receptor Stimulated Calcium Oscillations in Human Embryonic Kidney Cells
,Barbara Wedel, Rebecca R Boyles, James W Putney, and Gary S Bird,
J Physiol. 2007 Mar 15;579(Pt 3):679-89.
[STIM2]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224102 | STIM2 (Myc-DDK-tagged)-Human stromal interaction molecule 2 (STIM2), transcript variant 2 |
CNY 6,104.00 |
|
| RC224102L1 | Lenti ORF clone of Human stromal interaction molecule 2 (STIM2), transcript variant 2, Myc-DDK-tagged |
CNY 8,504.00 |
|
| RC224102L2 | Lenti ORF clone of Human stromal interaction molecule 2 (STIM2), transcript variant 2, mGFP tagged |
CNY 9,690.00 |
|
| RC224102L3 | Lenti ORF clone of Human stromal interaction molecule 2 (STIM2), transcript variant 2, Myc-DDK-tagged |
CNY 9,690.00 |
|
| RC224102L4 | Lenti ORF clone of Human stromal interaction molecule 2 (STIM2), transcript variant 2, mGFP tagged |
CNY 9,690.00 |
|
| RG224102 | STIM2 (tGFP-tagged) - Human stromal interaction molecule 2 (STIM2), transcript variant 2 |
CNY 7,704.00 |
