NRG1 (AF009227) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Vector	pCMV6 series
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for AF009227, the custom clone sequence may differ by one or more nucleotides ATGGACGTGAAGGAGAGGAAGCCTTACCGCTCGCTGACCCGGCGCCGCGACGCCGAGCGC CGCTACACCAGCTCGTCCGCGGACAGCGAGGAGGGCAAAGCCCCGCAGAAATCGTACAGC TCCAGCGAGACCCTGAAGGCCTACGACCAGGACGCCCGCCTAGCCTATGGCAGCCGCGTC AAGGACATTGTGCCGCAGGAGGCCGAGGAATTCTGCCGCACAGGTGCCAACTTCACCCTG CGGGAGCTGGGGCTGGAAGAAGTAACGCCCCCTCACGGGACCCTGTACCGGACAGACATT GGCCTCCCCCACTGCGGCTACTCCATGGGGGCTGGCTCTGATGCCGACATGGAGGCTGAC ACGGTGCTGTCCCCTGAGCACCCCGTGCGTCTGTGGGGCCGGAGCACACGGTCAGGGCGC AGCTCCTGCCTGTCCAGCCGGGCCAATTCCAATCTCACACTCACCGACACCGAGCATGAA AACACTGAGACTGATCATCCGGGCGGCCTGCAGAACCACGCGCGGCTCCGGACGCCGCCG CCGCCGCTCTCGCACGCCCACACCCCCAACCAGCACCACGCGGCCTCCATTAACTCCCTG AACCGGGGCAACTTCACGCCGAGGAGCAACCCCAGCCCGGCCCCCACGGACCACTCGCTC TCCGGAGAGCCCCCTGCCGGCGGCGCCCAGGAGCCTGCCCACGCCCAGGAGAACTGGCTG CTCAACAGCAACATCCCCCTGGAGACCAGAAACCTAGGCAAGCAGCCATTCCTAGGGACA TTGCAGGACAACCTCATTGAGATGGACATTCTCGGCGCCTCCCGCCATGATGGGGCTTAC AGTGACGGGCACTTCCTCTTCAAGCCTGGAGGCACCTCCCCGCTCTTCTGCACCACATCA CCAGGGTACCCACTGACGTCCAGCACAGTGTACTCTCCTCCGCCCCGACCCCTGCCCCGC AGCACCTTCGCCCGGCCGGCCTTTAACCTCAAGAAGCCCTCCAAGTACTGTAACTGGAAG TGCGCAGCCCTGAGCGCCATCGTCATCTCAGCCACTCTGGTCATCCTGCTGGCATACTTT GTGGCCATGCACCTGTTTGGCCTAAACTGGCACCTGCAGCCGATGGAGGGGCAGATGTAT GAGATCACGGAGGACACAGCCAGCAGTTGGCCTGTGCCAACCGACGTCTCCCTATACCCC TCAGGGGGCACTGGCTTAGAGACCCCTGACAGGAAAGGCAAAGGAACCACAGAAGGAAAG CCCAGTAGTTTCTTTCCAGAGGACAGTTTCATAGATTCTGGAGAAATTGATGTGGGAAGG CGAGCTTCCCAGAAGATTCCTCCTGGCACTTTCTGGAGATCTCAAGTGTTCATAGACCAT CCTGTGCATCTGAAATTCAATGTGTCTCTGGGAAAGGCAGCCCTGGTTGGCATTTATGGC AGAAAAGGCCTCCCTCCTTCACATACACAGTTTGACTTTGTGGAGCTGCTGGATGGCAGG AGGCTCCTAACCCAGGAGGCGCGGAGCCTAGAGGGGACCCCGCGCCAGTCTCGGGGAACT GTGCCCCCCTCCAGCCATGAGACAGGCTTCATCCAGTATTTGGATTCAGGAATCTGGCAC TTGGCTTTTTACAATGACGGAAAGGAGTCAGAAGTGGTTTCCTTTCTCACCACTGCCATT GCCTTGCCTCCCCGATTGAAAGAGATGAAAAGCCAGGAATCGGCTGCAGGTTCCAAACTA GTCCTTCGGTGTGAAACCAGTTCTGAATACTCCTCTCTCAGATTCAAGTGGTTCAAGAAT GGGAATGAATTGAATCGAAAAAACAAACCACAAAATATCAAGATACAAAAAAAGCCAGGG AAGTCAGAACTTCGCATTAACAAAGCATCACTGGCTGATTCTGGAGAGTATATGTGCAAA GTGATCAGCAAATTAGGAAATGACAGTGCCTCTGCCAATATCACCATCGTGGAATCAAAC GAGATCATCACTGGTATGCCAGCCTCAACTGAAGGAGCATATGTGTCTTCAGAGTCTCCC ATTAGAATATCAGTATCCACAGAAGGAGCAAATACTTCTTCATCTACATCTACATCCACC ACTGGGACAAGCCATCTTGTAAAATGTGCGGAGAAGGAGAAAACTTTCTGTGTGAATGGA GGGGAGTGCTTCATGGTGAAAGACCTTTCAAACCCCTCGAGATACTTGTGCAAGTGCCCA AATGAGTTTACTGGTGATCGCTGCCAAAACTACGTAATGGCCAGCTTCTACAGTACGTCC ACTCCCTTTCTGTCTCTGCCTGAA
Restriction Sites	Please inquire
ACCN	AF009227
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	AF009227.1, AAC51756.1
RefSeq Size	3111 bp
RefSeq ORF	3111 bp
Locus ID	3084
Domains	ig, IGc2, IG, EGF, EGF
Protein Families	Druggable Genome, Secreted Protein, Transcription Factors, Transmembrane
Protein Pathways	ErbB signaling pathway
Gene Summary	The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.