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Synapsin I (SYN1) (NM_133499) Human Untagged Clone
CAT＃: SC314376
SYN1 (untagged)-Human synapsin I (SYN1), transcript variant Ib
CNY 13,020.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EPILX; MRX50; SYN1a; SYN1b; SYNI |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC314376 representing NM_133499.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGAACTACCTGCGGCGCCGCCTGTCGGACAGCAACTTTATGGCCAATCTGCCAAATGGGTACATGACA GACCTGCAGCGTCCGCAGCCGCCCCCACCGCCGCCCGGTGCCCACAGCCCCGGAGCCACGCCCGGTCCC GGGACCGCCACTGCCGAGAGGTCCTCCGGGGTCGCCCCAGCGGCCTCTCCGGCCGCCCCTAGCCCCGGG TCCTCGGGGGGCGGTGGCTTCTTCTCGTCGCTGTCCAACGCGGTCAAGCAGACCACGGCGGCGGCAGCT GCCACCTTCAGCGAGCAGGTGGGCGGCGGCTCTGGGGGCGCAGGCCGCGGGGGAGCCGCCTCCAGGGTG CTGCTGGTCATCGACGAGCCGCACACCGACTGGGCAAAATACTTCAAAGGGAAAAAGATCCATGGAGAA ATTGACATTAAAGTAGAACAGGCCGAATTCTCTGATCTCAACCTTGTGGCCCATGCCAATGGTGGATTC TCTGTGGATATGGAAGTTCTTCGGAATGGGGTGAAGGTCGTGCGGTCTCTGAAGCCGGATTTTGTGCTG ATCCGCCAGCACGCCTTCAGCATGGCACGCAACGGAGACTACCGCAGTTTGGTCATTGGGCTGCAGTAT GCTGGAATCCCCAGTGTTAACTCCTTGCATTCTGTCTACAACTTCTGTGACAAGCCCTGGGTGTTTGCC CAGATGGTTCGACTGCATAAGAAACTGGGGACAGAAGAATTCCCTCTAATTGATCAGACCTTCTACCCC AATCACAAAGAAATGCTCAGCAGTACAACGTACCCCGTGGTTGTGAAGATGGGGCACGCACACTCTGGG ATGGGCAAGGTCAAGGTTGACAACCAGCATGACTTCCAGGACATCGCAAGTGTCGTGGCACTGACCAAG ACGTATGCCACTGCCGAGCCCTTCATCGATGCCAAATATGACGTGCGTGTCCAGAAGATTGGGCAGAAC TACAAGGCCTACATGAGGACGTCAGTGTCAGGGAACTGGAAGACCAATACTGGCTCTGCGATGCTGGAG CAAATTGCCATGTCTGACAGATACAAGCTGTGGGTGGACACGTGCTCAGAGATTTTTGGGGGACTGGAC ATCTGCGCAGTGGAAGCGCTACATGGCAAGGACGGAAGGGATCACATCATTGAGGTGGTGGGTTCCTCC ATGCCGCTCATTGGTGACCACCAGGATGAAGACAAACAGCTCATCGTAGAGCTCGTGGTCAACAAGATG GCTCAGGCCCTGCCCCGGCAGCGACAGCGGGATGCCTCCCCTGGCAGGGGCTCCCATGGCCAGACTCCG TCCCCAGGGGCCCTGCCCTTGGGCCGCCAGACCTCCCAGCAGCCCGCAGGGCCCCCGGCTCAGCAGCGA CCCCCACCACAGGGCGGCCCTCCACAGCCGGGTCCAGGCCCCCAGCGCCAGGGACCCCCATTGCAGCAG CGCCCGCCCCCGCAGGGCCAGCAGCACCTTTCAGGCCTTGGACCCCCAGCTGGCAGCCCCCTGCCCCAG CGCCTTCCAAGTCCCACCTCAGCGCCCCAGCAGCCCGCGTCCCAGGCCGCGCCGCCGACCCAGGGTCAA GGCCGCCAATCCCGGCCAGTGGCGGGAGGCCCCGGGGCGCCTCCAGCAGCCCGCCCGCCCGCCTCTCCG TCTCCCCAGCGCCAGGCGGGCCCCCCACAGGCTACCCGTCAGACATCCGTCTCTGGCCCGGCTCCGCCA AAGGCCTCTGGGGCCCCACCGGGCGGGCAGCAGCGCCAGGGCCCGCCCCAGAAACCCCCAGGCCCAGCC GGCCCCACACGCCAGGCCAGCCAGGCGGGTCCCGTGCCCCGCACTGGGCCACCCACCACGCAGCAGCCT CGGCCCAGCGGCCCGGGCCCCGCTGGACGTCCCAAACCACAGCTGGCCCAGAAACCCAGCCAGGACGTG CCGCCACCCGCCACCGCCGCTGCAGGGGGACCTCCGCACCCCCAGCTCAAAGCCAGCCCCGCCCAGGCC CAGCCTTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_133499 |
| Insert Size | 2010 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_133499.2 |
| RefSeq Size | 3172 bp |
| RefSeq ORF | 2010 bp |
| Locus ID | 6853 |
| UniProt ID | P17600 |
| MW | 70 kDa |
| Gene Summary | This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (Ib) utilizes an alternative splice acceptor site in terminal exon compared to variant Ia, resulting in the lack of an internal segment and a frameshift. This variant encodes isoform Ib, which contains a shorter carboxyl terminus and a distinct domain F, as compared to isoform Ia. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217800 | SYN1 (Myc-DDK-tagged)-Human synapsin I (SYN1), transcript variant Ib |
CNY 4,904.00 |
|
| RC217800L3 | Lenti-ORF clone of SYN1 (Myc-DDK-tagged)-Human synapsin I (SYN1), transcript variant Ib |
CNY 7,700.00 |
|
| RC217800L4 | Lenti-ORF clone of SYN1 (mGFP-tagged)-Human synapsin I (SYN1), transcript variant Ib |
CNY 7,700.00 |
|
| RG217800 | SYN1 (tGFP-tagged) - Human synapsin I (SYN1), transcript variant Ib |
CNY 6,370.00 |
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