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SEPTIN4 (NM_080415) Human Untagged Clone
CAT＃: SC312764
41521 (untagged)-Human septin 4 (SEPT4), nuclear gene encoding mitochondrial protein, transcript variant 2
CNY 2,400.00
CNY 6,270.00
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARTS; BRADEION; C17orf47; CE5B3; H5; hCDCREL-2; hucep-7; MART; PNUTL2; SEP4; SEPT4 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_080415 edited
GGGTGACGGCGGTGCTGCGAGGTCGGCGCGCAGCTCCGCCGCGGGTCGCTCGGGCGCTGT CCAGGCGGAGCCGGCCCCGCCCGGGCTGCAGCCATGATCAAGCGTTTCCTGGAGGACACC ACGGATGATGGAGAACTGAGCAAGTTCGTGAAGGATTTCTCAGGAAATGCGAGCTGCCAC CCACCAGAGGCTAAGACCTGGGCATCCAGGCCCCAAGTCCCGGAGCCAAGGCCCCAGGCC CCGGACCTCTATGATGATGACCTGGAGTTCAGACCCCCCTCGCGGCCCCAGTCCTCTGAC AACCAGCAGTACTTCTGTGCCCCAGCCCCTCTCAGCCCATCTGCCAGGCCCCGCAGCCCA TGGGGCAAGCTTGATCCCTATGATTCCTCTGAGGATGACAAGGAGTATGTGGGCTTTGCA ACCCTCCCCAACCAAGTCCACCGAAAGTCCGTGAAGAAAGGCTTTGACTTTACCCTCATG GTGGCAGGAGAGTCTGGCCTGGGCAAATCCACACTTGTCAATAGCCTCTTCCTCACTGAT CTGTACCGGGACCGGAAACTTCTTGGTGCTGAAGAGAGGATCATGCAAACTGTGGAGATC ACTAAGCATGCAGTGGACATAGAAGAGAAGGGTGTGAGGCTGCGGCTCACCATTGTGGAC ACACCAGGTTTTGGGGATGCAGTCAACAACACAGAGTGCTGGAAGCCTGTGGCAGAATAC ATTGATCAGCAGTTTGAGCAGTATTTCCGAGACGAGAGTGGCCTGAACCGAAAGAACATC CAAGACAACAGGGTGCACTGCTGCCTGTACTTTATCTCACCCTTCGGCCATGGGTATGGT CCAAGCCTGAGGCTCCTGGCACCACCGGGTGCTGTCAAGGGAACAGGCCAAGAGCACCAG GGGCAGGGCTGCCACTAGCAGGTGGTCACAGGTTCCTGTTCCCCAGGCTCCGGCCATTGG ATGTTGAATTCATGAAGGCCCTGCATCAGCGGGTCAACATCGTGCCTATCCTGGCTAAGG CAGACACACTGACACCTCCCGAAGTGGACCACAAGAAACGCAAAATCCGGGAGGAGATTG AGCATTTTGGAATCAAGATCTATCAATTCCCAGACTGTGACTCTGATGAGGATGAGGACT TCAAATTGCAGGACCAAGCCCTAAAGGAAAGCATCCCATTTGCAGTAATTGGCAGCAACA CTGTAGTAGAGGCCAGAGGGCGGCGAGTTCGGGGTCGACTCTACCCCTGGGGCATCGTGG AAGGACCTGAAGGATGTGACGCGGGAGACACATTATGAGAACTACCGGGCACAGTGCATC CAGAGCATGACCCGCCTGGTGGTGAAGGAACGGAATCGCAACAAACTGACTCGGGAAAGT GGTACCGACTTCCCCATCCCTGCTGTCCCACCAGGGACAGATCCAGAAACTGAGAAGCTT ATCCGAGAGAAAGATGAGGAGCTGCGGCGGATGCAGGAGATGCTACACAAAATACAAAAA CAGATGAAGGAGAACTATTAACTGGCTTTCAGCCCTGGATATTTAAATCTCCTCCTCTTC TTCCTGTCCATGCCGGCCCCTCCCAGCACCAGCTCTGCTCAGGCCCCTTCAGCTACTGCC ACTTCGCCTTACATCCCTGCTGACTGCCCAGAGACTCAGAGGAAATAAAGTTTAATAAAT CTGTAGTGAGAATCCATCAGGCAACACAAAAAAAA >OriGene 5' read for NM_080415 unedited
GTAGGACTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGGCACGAGGCCTCGTGCCG AATTCGGCACGAGGGGGTGACGGCGGTGCTGCGAGGTCGGCGCGCAGCTCCGCCGCGGGT CGCTCGGGCGCTGTCCAGGCGGAGCCGGCCCCGCCCGGGCTGCAGCCATGATCAAGCGTT TCCTGGAGGACACCACGGATGATGGAGAACTGAGCAAGTTCGTGAAGGATTTCTCAGGAA ATGCGAGCTGCCACCCACCAGAGGCTAAGACCTGGGCATCCAGGCCCCAAGTCCCGGAGC CAAGGCCCCAGGCCCCGGACCTCTATGATGATGACCTGGAGTTCAGACCCCCCTCGCGGC CCCAGTCCTCTGACAACCAGCAGTACTTCTGTGCCCCAGCCCCTCTCAGCCCATCTGCCA GGCCCCGCAGCCCATGGGGCAAGCTTGATCCCTATGATTCCTCTGAGGATGACAAGGAGT ATGTGGGCTTTGCAACCCTCCCCAACCAAGTCCACCGAAAGTCCGTGAAGAAAGGCTTTG ACTTTACCCTCATGGTGGCAGGAGAGTCTGGCCTGGGCAAATCCACACTTGTCAATAGCC TCTTCCTCACTGATCTGTACCGGGACCGGAAACTTCTTGGTGCTGAAGAGAGGATCATGC AAACTGTGGAGATCACTAAGCATGCAGTGGACATAGAAGAGAAGGGTGTGAGGCTGCGGC TCACCATTGTGGACACACCAGGTTTTGGGGATGCAGTCAACAACACAGAGTGCTGGAAGC CTGTGGCAGATACATTGATCAGCAGTTTGAGCAGTATTTCCCGAGACGAGAGTGGCCTGA ACCGAAAGACATCCAAGACACAGGTGCACTGCTGCCTGTACTTTATTCTCACCCTTCGGC CATGGGTTATGGTTCCAGGCCTGAGGCTTCCTGGCAAC >OriGene 3' read for NM_080415 unedited
CGTGATGCACCTTCAGGGCCGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGG ATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCCCCCAACAAATTTAT AAAATTTTATTTCCCCTAATTCTCGGGGCATTCCCCAGGGATGTAAGGCAAAGTGGCATT ACCTAAAGGGGCCTGACCAAACCTGGGGCGGGGAGGGGCCGGCTTGGACAGAAAAAAAAG AAAAAAATTTAAATTTCCGGGGCTAAAACCCATTTAAAATTTCCCCTTCATCGGTTTTTG TTTTTGGGGAACCATCTCCGGCACCCCCCGCACCTCCTCATTTTTTTTTCGAATAACCTT CTAATTTTCTGAATCTGCCCCGGGGGGAACACCGGGGATGGGAAATTCGGTCCCCTTTTC CCAATTCATTTTGTTGCAATTCCTTTCTTTCACCACCAGGCGGGTCATGCTTTGAATGCA TTGTCCCCGGTATTTCTAAAAATGTGTCTCCCGGTAAAACCTTAAGGTCCTTCCAAATGC CCAGGGGTAAAGTCGACCCCGAACTCGCCGCCCTCTGGCCTTTATAAAGTGTGGCTGCCA TTACTGAAATGGGGACGCTTTCCTTTAGGGCTTGGTCCGCATTTGAATTCCTCATCCTCA TCAGAGTACAGTCTGGGAATTGATATATCTGATCAAAATGCTCATCTCTCCCGGATTTGC GTTTCTTGGGTCACTTCGGGAGTGTCAGTGTGTCTGCCTTACCAGAAGCCATGTGACCCG TGATGCGGCCTATGGAATCACATCCATGCCGAACCTGGAAACAGAACTGT |
| Restriction Sites | Please inquire |
| ACCN | NM_080415 |
| Insert Size | 1700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_080415.1, NP_536340.1 |
| RefSeq Size | 1911 bp |
| RefSeq ORF | 825 bp |
| Locus ID | 5414 |
| UniProt ID | O43236 |
| Domains | GTP_CDC |
| Gene Summary | This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer. [provided by RefSeq, Nov 2010] Transcript Variant: This variant (2) differs in the 5' UTR and coding region and initiates translation at an alternate start codon, compared to variant 7. This transcript contains an early translation termination site, rendering this transcript a candidate for nonsense-mediated mRNA decay (NMD). However, the encoded protein (isoform 2, also known as ARTS, SEPT4_i2), with distinct N- and C-termini compared to isoform 5, has been shown to be expressed in vivo, and characterized as a mitochondrial pro-apoptotic, tumor suppressor protein having a role in cancer (PMIDs: 11146656, 15254396). |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215054 | SEPT4 (Myc-DDK-tagged)-Human septin 4 (SEPT4), nuclear gene encoding mitochondrial protein, transcript variant 2 |
CNY 2,400.00 |
|
| RC215054L1 | Lenti ORF clone of Human septin 4 (SEPT4), nuclear gene encoding mitochondrial protein, transcript variant 2, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC215054L2 | Lenti ORF clone of Human septin 4 (SEPT4), nuclear gene encoding mitochondrial protein, transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC215054L3 | Lenti ORF clone of Human septin 4 (SEPT4), nuclear gene encoding mitochondrial protein, transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC215054L4 | Lenti ORF clone of Human septin 4 (SEPT4), nuclear gene encoding mitochondrial protein, transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG215054 | 41521 (tGFP-tagged) - Human septin 4 (SEPT4), nuclear gene encoding mitochondrial protein, transcript variant 2 |
CNY 4,000.00 |
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