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HIRA (NM_003325) Human Untagged Clone
CAT＃: SC311322
HIRA (untagged)-Human HIR histone cell cycle regulation defective homolog A (S. cerevisiae) (HIRA)
CNY 10,450.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DGCR1; TUP1; TUPLE1 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_003325, the custom clone sequence may differ by one or more nucleotides
ATGAAGCTCCTGAAGCCGACCTGGGTCAACCACAATGGCAAGCCGATTTTTTCAGTTGAT ATTCACCCTGACGGGACCAAGTTCGCAACTGGAGGACAAGGGCAGGATTCTGGGAAGGTT GTGATCTGGAATATGTCTCCAGTCCTCCAGGAGGATGACGAGAAGGATGAAAATATTCCC AAGATGCTTTGCCAGATGGACAATCACTTAGCATGTGTGAACTGTGTGCGGTGGTCAAAC AGTGGGATGTATTTAGCTTCTGGGGGAGATGACAAACTGATTATGGTGTGGAAGCGGGCT ACGTACATCGGCCCCAGCACCGTGTTCGGCTCCAGTGGTAAGCTTGCCAATGTGGAGCAG TGGCGGTGTGTCTCTATCCTCCGGAATCATTCAGGCGATGTGATGGATGTAGCATGGTCT CCCCACGATGCCTGGCTAGCCTCATGCAGCGTGGATAACACTGTCGTCATCTGGAATGCT GTAAAGTTCCCAGAAATTCTAGCTACTCTGAGAGGTCATTCTGGCTTGGTCAAAGGGTTG ACATGGGACCCTGTTGGTAAATACATAGCTTCTCAAGCTGATGACCGCAGCCTAAAGGTG TGGAGGACGCTGGACTGGCAGTTGGAGACCAGCATCACCAAGCCTTTTGATGAGTGTGGA GGAACGACCCATGTGTTGCGGCTCAGCTGGTCACCTGATGGGCATTACCTGGTGTCTGCC CATGCCATGAACAACTCAGGCCCCACTGCCCAGATCATCGAACGGGAGGGATGGAAGACC AACATGGACTTTGTTGGGCACCGGAAAGCTGTGACTGTCGTGAAATTCAACCCAAAAATC TTCAAAAAGAAGCAGAAGAATGGGAGTTCTGCGAAGCCTAGCTGCCCGTACTGCTGCTGT GCTGTTGGCAGCAAGGACCGCTCGCTTTCTGTCTGGCTCACATGTCTGAAACGGCCGCTG GTGGTCATCCATGAACTGTTTGACAAATCCATCATGGATATTTCCTGGACTCTGAATGGG CTGGGCATCTTGGTATGCTCTATGGACGGCTCTGTGGCATTCCTCGACTTCTCCCAGGAT GAGCTTGGCGATCCCCTGAGCGAGGAGGAGAAGAGCCGCATTCACCAGTCCACCTATGGC AAGAGCCTAGCCATCATGACCGAGGCCCAGCTCTCCACAGCCGTCATTGAGAACCCTGAG ATGCTCAAGTACCAGCGAAGGCAGCAGCAGCAGCAGCTGGACCAGAAGAGTGCTGCGACC AGGGAGATGGGCTCAGCCACCTCAGTCGCAGGCGTTGTCAACGGGGAGAGTCTTGAAGAT ATCAGGAAGAATCTTTTGAAGAAACAAGTTGAGACTCGGACAGCAGATGGCCGGAGAAGA ATCACGCCTCTCTGCATAGCACAGCTGGACACTGGGGACTTCTCCACGGCATTCTTTAAC AGCATCCCCCTCTCGGGCTCCCTGGCGGGCACCATGCTCTCTTCTCATAGCAGTCCACAG CTACTGCCACTGGACTCCAGTACCCCTAACTCCTTCGGCGCCTCGAAGCCTTGCACAGAG CCTGTGGTGGCTGCCAGTGCCAGACCTGCAGGCGATTCTGTCAATAAAGACAGTATGAAT GCTACCTCTACTCCTGCTGCATTGTCACCTTCTGTGTTAACGACCCCGTCCAAGATCGAA CCCATGAAAGCGTTTGACTCCCGGTTCACAGAGCGGTCCAAAGCCACACCAGGTGCTCCT GCCCTGACCAGCATGACTCCGACAGCTGTGGAAAGGTTAAAAGAGCAGAACCTTGTGAAA GAGCTGAGGCCCCGAGACCTCCTGGAGAGCAGCAGTGACAGCGATGAGAAAGTCCCTTTG GCTAAGGCTTCCTCACTGTCCAAGCGAAAACTTGAGCTTGAGGTAGAGACAGTAGAGAAG AAGAAGAAAGGGCGGCCTCGGAAGGACTCTCGTCTCATGCCTGTGTCTCTGTCTGTCCAG TCTCCAGCTGCCCTAACCGCAGAGAAGGAGGCCATGTGTCTGTCTGCACCAGCACTTGCA CTGAAGCTGCCAATTCCAAGCCCCCAGAGAGCATTCACCCTCCAGGTCAGCTCCGATCCT TCCATGTACATTGAGGTGGAGAATGAAGTGACAGTGGTGGGGGGCGTGAAGCTGAGCCGC CTGAAGTGCAACCGGGAAGGGAAGGAGTGGGAGACGGTACTCACCAGCCGGATCCTCACT GCTGCGGGCAGCTGTGACGTGGTGTGTGTCGCCTGTGAAAAAAGGATGCTGTCAGTGTTC TCCACCTGTGGTCGCCGTCTCCTCTCTCCCATCCTCCTGCCATCCCCGATCTCTACTTTG CATTGCACAGGCTCCTACGTCATGGCGCTCACCGCTGCAGCCACACTCTCTGTCTGGGAT GTTCACAGACAGGTGGTTGTGGTGAAAGAAGAGTCTCTACACTCCATCCTGGCAGGAAGT GATATGACGGTATCACAGATCTTGCTGACGCAGCATGGAATCCCAGTAATGAACCTGTCC GATGGGAAGGCGTACTGCTTTAATCCGTCACTTTCCACATGGAACCTGGTTTCTGACAAG CAGGACTCACTGGCTCAGTGTGCAGACTTTAGGAGCAGCCTGCCATCCCAGGACGCCATG CTGTGCTCAGGACCGTTAGCCATAATCCAGGGCCGCACCTCCAACTCGGGAAGGCAGGCT GCCCGGCTCTTCTCCGTGCCTCATGTGGTGCAGCAAGAGACCACCCTGGCCTACCTAGAG AACCAGGTGGCAGCAGCACTCACCCTGCAGTCCAGCCACGAGTACCGCCATTGGCTCCTC GTCTACGCACGGTACCTCGTAAACGAAGGGTTTGAATACCGACTTCGAGAAATATGCAAG GACTTACTGGGTCCGGTTCACTACTCCACTGGAAGCCAGTGGGAGTCAACAGTAGTGGGT CTGCGGAAGAGGGAGCTGCTGAAGGAGCTGCTACCAGTCATCGGGCAGAACCTCCGATTC CAGCGCCTCTTCACCGAGTGTCAGGAACAGCTCGACATCCTGAGGGACAAGTAG |
| Restriction Sites | Please inquire |
| ACCN | NM_003325 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003325.3, NP_003316.3 |
| RefSeq Size | 4013 bp |
| RefSeq ORF | 3054 bp |
| Locus ID | 7290 |
| UniProt ID | P54198 |
| Domains | WD40 |
| Protein Families | Transcription Factors |
| Gene Summary | This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008] |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208049 | HIRA (Myc-DDK-tagged)-Human HIR histone cell cycle regulation defective homolog A (S. cerevisiae) (HIRA) |
CNY 7,080.00 |
|
| RC208049L3 | Lenti-ORF clone of HIRA (Myc-DDK-tagged)-Human HIR histone cell cycle regulation defective homolog A (S. cerevisiae) (HIRA) |
CNY 10,260.00 |
|
| RC208049L4 | Lenti-ORF clone of HIRA (mGFP-tagged)-Human HIR histone cell cycle regulation defective homolog A (S. cerevisiae) (HIRA) |
CNY 10,260.00 |
|
| RG208049 | HIRA (tGFP-tagged) - Human HIR histone cell cycle regulation defective homolog A (S. cerevisiae) (HIRA) |
CNY 9,220.00 |
