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BRIT1 (MCPH1) (NM_024596) Human Untagged Clone
CAT＃: SC311118
MCPH1 (untagged)-Human microcephalin 1 (MCPH1), transcript variant 1
CNY 5,432.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BRIT1; MCT |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_024596 edited
ATGGCGGCCCCCATCCTGAAAG::::::TGGCCTATGTTGAAGTGTGGTCATCCAATGGA ACAGAAAATTATTCAAAGACATTTACAACACAGCTTGTGGATATGGGGGCAAAGGTTTCA AAAACTTTTAACAAACAAGTAACTCACGTTATCTTCAAAGATGGCTACCAGAGCACTTGG GACAAAGCTCAGAAGAGAGGCGTAAAGCTCGTTTCGGTGCTCTGGGTTGAAAAATGCAGG ACAGCTGGAGCACACATTGATGAATCATTGTTCCCTGCAGCTAATATGAATGAACACTTA TCAAGCCTAATTAAAAAAAAACGTAAATGTATGCAGCCCAAAGATTTTAATTTTAAAACA CCAGAAAATGATAAGAGATTTCAGAAGAAATTTGAGAAAATGGCTAAAGAGCTACAAAGG CAAAAAACAAATCTAGATGATGATGTACCTATTCTCTTATTTGAATCTAATGGTTCATTA ATATATACTCCCACAATTGAAATTAATAGTAGTCACCACAGCGCAATGGAGAAGAGATTA CAAGAGATGAAGGAGAAAAGGGAAAATCTTTCCCCCACCTCTTCCCAAATGATTCAGCAG TCTCATGATAATCCAAGTAACTCTCTGTGTGAAGCACCTTTGAACATTTCACGTGATACT TTGTGTTCAGATGAATACTTTGCTGGTGGCTTACACTCATCTTTTGATGATCTTTGTGGA AACTCAGGATGTGGAAATCAGGAAAGGAAGTTGGAAGGATCCATTAATGACATTAAAAGT GATGTGTGTATTTCTTCACTTGTATTGAAAGCAAATAATATTCATTCATCACCATCTTTC ACTCACCTCGATAAATCAAGTCCTCAGAAATTTCTGAGTAATCTTTCAAAGGAAGAAATA AACTTGCAAAGAAATATTGCAGGTAAAGTAGTCACCCCTSACCAAAAGCAGGCTGCAGGT ATGTCTCAGGAGACGTTTGAAGAGAAGTATCGTTTGTCTCCTACCTTATCTTCAACAAAA GGCCACCTTTTGATACATTCAAGACCCAGGAGTTCCTCAGTAAAGAGAAAAAGAGTATCA CATGGCTCCCATTCACCTCCGAAGGAAAAATGCAAGAGAAAGAGGAGCACCAGGAGATCT ATCATGCCGAGGCTGCAGCTGTGCAGGTCGGAAGRCAGGCTGCAGCACGTGGCGGGACCT GCCCTGGAGGCTCTTAGCTGTGGGGAGTCTTCATATGATGACTATTTTTCACCTGATAAT CTTAAGGAAAGGTATTCAGAGAATCTTCCTCCTGAATCTCAGCTGCCATCAAGCCCTGCT CAGTTGAGCTGCAGAAGTCTTTCTAAGAAGGAGAGAACAAGCATATTTGAAATGTCTGAT TTTTCCTGCGTTGGCAAAAAAACCAGAACAGTTGACATTACCAATTTCACAGCAAAAACC ATCTCCAGTCCTCGGAAAACTGGAAATGGTGAAGGCCGTGCAACTTCGAGTTGCGTGACT TCTGCCCCTGAAGAAGCCCTAAGGTGTTGTAGACAGGCTGGGAAAGAAGACGCATGCCCA GAGGGAAATGGCTTTTCTTACACCATTGAGGACCCTGCTCTTCCAAAAGGACATGATGAT GATTTAACTCCTTTGGAAGGAAGCCTTGAAGAAATGAAAGAAGCGGTTGGTCTGAAAAGC ACACAGAACAAAGGTACCACTTCCAAAATATCAAACTCCTCTGAAGGCGAAGCCCAGAGT GAACATGAGCCATGTTTTATAGTTGACTGTAACATGGAGACGTCTACAGAAGAGAAGGAA AACTTACCCGGAGGATACAGTGGAAGTGTTAAAAATAGACCAACAAGGCATGATGTTTTA GATGACTCATGTGACGGCTTTAAGGACCTCATCAAACCTCATGAGGAATTGAAGAAAAGT GGGAGAGGCAAAAAGCCAACAAGAACATTAGTCATGACAAGCATGCCATCTGAAAAGCAG AATGTCGTCATCCAGGTTGTGGATAAATTGAAAGGCTTTTCAATTGCACCAGACGTCTGT GAGACCACGACTCACGTGCTTTCCGGGAAGCCACTTCGCACCCTGAATGTGCTGCTGGGA ATTGCGCGTGGCTGCTGGGTTCTCTCTTATGATTGGGTGCTATGGTCTTTAGAATTGGGT CACTGGATTTCTGAGGAGCCGTTCGAACTGTCTCACCACTTCCCTGCAGCTCCCCTGTGC CGAAGCGAGTGCCACTTGTCTGCAGGGCCGTACCGCGGAACCCTCTTTGCCGACCAGCCA GCGATGTTTGTCTCGCCTGCCAGCAGCCCCCCAGTGGCCAAGCTCTGTGAACTAGTCCAC CTGTGCGGAGGCCGGGTCAGCCAAGTCCCCCGCCAGGCCAGCATCGTCATCGGGCCCTAC AGCGGAAAGAAGAAAGCCACAGTCAAGTATCTGTCTGAGAAATGGGTCTTAGATTCCATC ACCCAGCACAAGGTCTGTGCCCCTGAAAACTACCTATTGTCACAATGA |
| Restriction Sites | Please inquire |
| ACCN | NM_024596 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a good match to NM_024596.1 except for 6bp deletion at 5' and one SNP. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_024596.1, NP_078872.1 |
| RefSeq Size | 2518 bp |
| RefSeq ORF | 2223 bp |
| Locus ID | 79648 |
| UniProt ID | Q8NEM0 |
| Domains | BRCT |
| Gene Summary | This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010] Transcript Variant: This variant (1, also known as MCPH1-FL) encodes isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224920 | MCPH1 (Myc-DDK-tagged)-Human microcephalin 1 (MCPH1), transcript variant 1 |
CNY 6,120.00 |
|
| RC224920L1 | Lenti ORF clone of Human microcephalin 1 (MCPH1), transcript variant 1, Myc-DDK-tagged |
CNY 8,520.00 |
|
| RC224920L2 | Lenti ORF clone of Human microcephalin 1 (MCPH1), transcript variant 1, mGFP tagged |
CNY 9,030.00 |
|
| RC224920L3 | Lenti ORF clone of Human microcephalin 1 (MCPH1), transcript variant 1, Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC224920L4 | Lenti ORF clone of Human microcephalin 1 (MCPH1), transcript variant 1, mGFP tagged |
CNY 9,030.00 |
|
| RG224920 | MCPH1 (tGFP-tagged) - Human microcephalin 1 (MCPH1), transcript variant 1 |
CNY 7,720.00 |
|
| SC318315 | MCPH1 (untagged)-Human microcephalin 1 (MCPH1), transcript variant 1 |
CNY 16,060.00 |
|
| SC318316 | MCPH1 (untagged)-Human microcephalin 1 (MCPH1), transcript variant 1 |
CNY 16,060.00 |
