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PML Protein (PML) (NM_033238) Human Untagged Clone
CAT＃: SC311116
PML (untagged)-Human promyelocytic leukemia (PML), transcript variant 1
CNY 6,464.00
货期*
现货
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MYL; PP8675; RNF71; TRIM19 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_033238 edited
CGAGAATCGAAACTAAGCTGGGGTCCATGGAGCCTGCACCCGCCCGATCTCCGAGGCCCC AGCAGGACCCCGCCCGGCCCCAGGAGCCCACCATGCCTCCCCCCGAGACCCCCTCTGAAG GCCGCCAGCCCAGCCCCAGCCCCAGCCCTACAGAGCGAGCCCCCGCTTCGGAGGAGGAGT TCCAGTTTCTGCGCTGCCAGCAATGCCAGGCGGAAGCCAAGTGCCCGAAGCTGCTGCCTT GTCTGCACACGCTGTGCTCAGGATGCCTGGAGGCGTCGGGCATGCAGTGCCCCATCTGCC AGGCGCCCTGGCCCCTAGGTGCAGACACACCCGCCCTGGATAACGTCTTTTTCGAGAGTC TGCAGCGGCGCCTGTCGGTGTACCGGCAGATTGTGGATGCGCAGGCTGTGTGCACCCGCT GCAAAGAGTCGGCCGACTTCTGGTGCTTTGAGTGCGAGCAGCTCCTCTGCGCCAAGTGCT TCGAGGCACACCAGTGGTTCCTCAAGCACGAGGCCCGGCCCCTAGCAGAGCTGCGCAACC AGTCGGTGCGTGAGTTCCTGGACGGCACCCGCAAGACCAACAACATCTTCTGCTCCAACC CCAACCACCGCACCCCTACGCTGACCAGCATCTACTGCCGAGGATGTTCCAAGCCGCTGT GCTGCTCGTGCGCGCTCCTTGACAGCAGCCACAGTGAGCTCAAGTGCGACATCAGCGCAG AGATCCAGCAGCGACAGGAGGAGCTGGACGCCATGACGCAGGCGCTGCAGGAGCAGGATA GTGCCTTTGGCGCGGTTCACGCGCAGATGCACGCGGCCGTCGGCCAGCTGGGCCGCGCGC GTGCCGAGACCGAGGAGCTGATCCGCGAGCGCGTGCGCCAGGTGGTAGCTCACGTGCGGG CTCAGGAGCGCGAGCTGCTGGAGGCTGTGGACGCGCGGTACCAGCGCGACTACGAGGAGA TGGCCAGTCGGCTGGGCCGCCTGGATGCTGTGCTGCAGCGCATCCGCACGGGCAGCGCGC TGGTGCAGAGGATGAAGTGCTACGCCTCGGACCAGGAGGTGCTGGACATGCACGGTTTCC TGCGCCAGGCGCTCTGCCGCCTGCGCCAGGAGGAGCCCCAGAGCCTGCAAGCTGCCGTGC GCACCGATGGCTTCGACGAGTTCAAGGTGCGCCTGCAGGACCTCAGCTCTTGCATCACCC AGGGGAAAGATGCAGCTGTATCCAAGAAAGCCAGCCCAGAGGCTGCCAGCACTCCCAGGG ACCCTATTGACGTTGACCTGCCCGAGGAGGCAGAGAGAGTGAAGGCCCAGGTTCAGGCCC TGGGGCTGGCTGAAGCCCAGCCTATGGCTGTGGTACAGTCAGTGCCCGGGGCACACCCCG TGCCAGTGTACGCCTTCTCCATCAAAGGCCCTTCCTATGGAGAGGATGTCTCCAATACAA CGACAGCCCAGAAGAGGAAGTGCAGCCAGACCCAGTGCCCCAGGAAGGTCATCAAGATGG AGTCTGAGGAGGGGAAGGAGGCAAGGTTGGCTCGGAGCTCCCCGGAGCAGCCCAGGCCCA GCACCTCCAAGGCAGTCTCACCACCCCACCTGGATGGACCGCCTAGCCCCAGGAGCCCCG TCATAGGAAGTGAGGTCTTCCTGCCCAACAGCAACCACGTGGCCAGTGGCGCCGGGGAGG CAGAGGAACGCGTTGTGGTGATCAGCAGCTCGGAAGACTCAGATGCCGAAAACTCGTCCT CCCGAGAGCTGGATGACAGCAGCAGTGAGTCCAGTGACCTCCAGCTGGAAGGCCCCAGCA CCCTCAGGGTCCTGGACGAGAACCTTGCTGACCCCCAAGCAGAAGACAGACCTCTGGTTT TCTTTGACCTCAAGATTGACAATGAAACCCAGAAGATTAGCCAGCTGGCTGCGGTGAACC GGGAAAGCAAGTTCCGCGTGGTCATCCAGCCTGAAGCCYTCTTCAGCATCTACTCCAAGG CCGTGTCCCTGGAGGTGGGGCTGCAGCACTTCCTCAGCTTTCTGAGCTCCATGCGCCGCC CTATCTTGGCCTGCTACAAGCTGTGGGGGCCTGGCCTCCCAAACTTCTTCCGGGCCCTGG AGGACATTAACAGGCTGTGGGAATTCCAGGAGGCCATCTCGGGCTTCCTGGCTGCCCTGC CTCTCATCCGGGAGCGTGTGCCCGGGGCCAGCAGCTTCAAACTCAAGAACCTGGCCCAGA CCTACCTGGCGAGAAACATGAGCGAGCGCAGCGCCATGGCTGCCGTGCTGGCCATGCGTG ACCTGTGCCGCCTCCTCGAGGTCTCCCCGGGCCCCCAGCTGGCCCAGCATGTCTACCCCT TCAGTAGCCTGCAGTGCTTTGCCTCCCTGCAGCCCCTGGTGCAGGCAGCTGTGCTGCCCC GGGCTGAGGCCCGCCTCCTGGCCCTACACAACGTGAGCTTCATGGAGCTGCTGAGTGCAC ACCGCCGTGACCGGCAGGGGGGCCTGAAGAAGTACAGCCGCTATCTAAGCCTGCAGACCA CCACGTTGCCCCCTGCCCAGCCTGCTTTCAACCTGCAGGCTCTGGGCACCTACTTTGAAG GCCTGTTGGAGGGTCCGGCGCTGGCACGGGCAGAAGGAGTCTCCACCCCACTTGCTGGCC GTGGCTTGGCAGAGAGGGCCTCCCAGCAGAGCTGAGAGGAGGGGGTGACCAGCTTGGAGT CTCTGGTGGGCAGAGAGGGATGGGGTCCCTGAGCCAGGCCCCACCCATCACAGCATTCCC AGGTCCTGGTACCCAGCCCTCAGTTGTCATTTGGTTCAGAATCAGTTCCCTTTCTCTGGG ACCAAATTTCCCTTCTCTAAACATCCTACAGAGAAGGTTCCAAAGCTGAGCACCCATCAC CCTAGGTGTGCACCAGACTCCTATTAGCCCCTCCTTCCAGGAGCTAGAACCAGGGAGGTC CTGAGTGAGGAAGGCATGACCTCTGGGCTCTCTAGGTGGCCCTGGTCTTGCCCCATCCAT CCCACCTGCCACTACCTTGGGTGTCCTTACAGCTCTGCCCTGACCCCAGCCCCTGCCCCT GGACACCTGCTGACAGCTCCCACACAGAACAGTCTGAGGTGATGCTGGCTACAGCCCTGG CAGCCCATGGCAACTCAAAGTGCCTTCCAAACCAAACTGCCCCTCATGAGGTTAGGGTCC CCCACCCTCCACCTGCCCAGAGGCCAACTCTGTTCCCTTCTCCTTTCATCCCAGAGGGGC CTCATCAGCAAAGACAGAAACTGATGTTCCATGCATGTCCCTGCTTCCAAAGCCTGACCT TCCAAAGCTTGCTTCCTTCCTCCTGGCTGCACAGACACCTCTGCTTGGCCACAGCTTTGC TCTTTGGTCCTCAGGCCACCAGACCCCTCACAGCATGGCCCTTGGCTCTTCCTGCACTGC CCTCACCCTCAGCCGTCCCAAGGAGTGCCCAGCACTACTCAGCATGTAGTCCAGGACCTG CGGCATCAGCATCCCCTGGGAGCTTCTTAGAAATGCAGACCTGTGGGCTCTACCACAGGC CTCTGGAATCAGAATCTTCAGGGTGGGGCCCAGCAGTCTGTGTTTTAACAGGTTCTCCCG GTGATGCTGGTGCATGCTCAAGTTTGAGAACCGCTGCTCTCATAGACTGCTCCTCCAAGG GGAAGCAGTGTGGAACAGCAGAGAAAGTCCCGTCCCTATCTCTGACTGTGCAGTGAGTGT GGCCTAGGAACAGGTCCCTTCCTAAGCTCTAGTGTCCCCATCTGTAAAATGGGCTGATTG GCCTCCACGGTCAGAGCGGCCATCTGGCTGTGCCATCCTGCATTTTTAGGAATGGAAAGC AGGCCTCTGAGGCAGTGGACAGGAAGACTTCTCATCCTTGAATTCTAGCTCCCATTCCAA ACTGTTAGTCCCCAACCTTGTGGTCACATCAGAGGTCAACAGCAGAACAGAGGCAGGTCA GGGTTGTCCGCTCTGATTAGCAGAACGACAGCCCCTTCCTCCTCCTCCCTCCTTCCCATC CCTACTCATTAGCTCCCTGCTCCTGGGATGCTTCCCAAGCAGCCCAGGCCTCTAGCCTCC ATGGCTGATGACCTCAGCTTTCACACTGGTGAAGTCTGTGTACCCATACTGCAGCCCCAT CCCATGGGGCCCCTGAAGACCCACTGAGGAATTCCGTAGGGTCTTGTTCCCACGACCGGA GTGCTGGCTCTCACAGTGAATTTTGATGCATTTAAAATAAGATTCTGATGCCAGACTGTT AAAATAGGCGCTGGTTCTGAAGCACCGATGGAAACAGATTGATGCAGATGGAAGGAGGAA GGGAGACTGGGCCCACTGATTTCCAGCCCCACCATGTGTGCTGTTTTCAGATGTGATTGA GGGGTGTTCTGCCCTGCCTCCACTGTCACAGCCTTTAATAAAGATGTGAATCTTGAAAAA AAAAAAAAAAAAAAA >OriGene 5' read for NM_033238 unedited
GGACGTCAGCATTTGTNATACGACTTCACTATAGGCGGCCGCGCAATTCGCACGAGCGAG AATCGAAACTAAGCTGGGGTCCATGGAGCCTGCACCCGCCCGATCTCCGAGGCCCCAGCA GGACCCCGCCCGGCCCCAGGAGCCCACCATGCCTCCCCCCGAGACCCCCTCTGAAGGCCG CCAGCCCAGCCCCAGCCCCAGCCCTACAGAGCGAGCCCCCGCTTCGGAGGAGGAGTTCCA GTTTCTGCGCTGCCAGCAATGCCAGGCGGAAGCCAAGTGCCCGAAGCTGCTGCCTTGTCT GCACACGCTGTGCTCAGGATGCCTGGAGGCGTCGGGCATGCAGTGCCCCATCTGCCAGGC GCCCTGGCCCCTAGGTGCAGACACACCCGCCCTGGATAACGTCTTTTTCGAGAGTCTGCA GCGGCGCCTGTCGGTGTACCGGCAGATTGTGGATGCGCAGGCTGTGTGCACCCGCTGCAA AGAGTCGGCCGACTTCTGGTGCTTTGAGTGCGAGCAGCTCCTCTGCGCCAAGTGCTTCGA GGCACACCAGTGGTTCCTCAAGCACGAGGCCCGGCCCCTAGCAGAGCTGCGCAACCAGTC GGTGCGTGAGTTCCTGGACGGCACCCGCAAGACCAACAACATCTTCTGCTCCAACCCCAA CCACCGCACCCCTACGCTGACCAGCATCTACTGCCGAGGATGTTCCAAGCCGCTGTGCTG CTCGTGCGCGCTCCTTGACAGCAGCCACAGTGAGCTCAAGTGCGACATCAGCGCAGAGAT CCAGCAGCGACAGGAAGAGCTGGACGCCATGACGCANGCGCTGCAGGAGCAAGATAGTGC CTTTGGCGCGGTTCACGCGCAGATGCACGNCGCCGTNCGCCAGCTGGGCCGCGCGCGTGC CGAGACCGAC >OriGene 3' read for NM_033238 unedited
CTTGGGATGGCACTTCCAGGTCCAGNAAAGCACTGGGGCAGGGTCACAGGGATGCCACCC GGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTT TTTTTTTTTTCAAGATTCACATCTTTATTAAAGGCTGTGACAGTGGAGGCAGGGCAAAAC ACCCCTCAATCACATCTGAAAACAGCACACATGGTGGGGCTGGAAATCAGTGGGCCCAGT CTCCCTTCCTCCTTCCATCTGCATCAATCTGTTTCCATCGGTGCTTCAGAACCAGCGCCT ATTTTAACAGTCTGGCATCAGAATCTTATTTTAAATGCATCAAAATTCACTGTGAGAGCC AGCACTCCGGTCGTGGGAACAAGACCCTACGGAATTCCTCAGTGGGTCTTCAGGGGCCCC ATGGGATGGGGCTGCAGTATGGGTACACAGACTTCACCAGTGTGAAAGCTGAGGTCATCA GCCATGGAGGCTAGAGGCCTGGGCTGCTTGGGAAGCATCCCAGGAGCAGGGAGCTAATGA GTAGGGATGGGAAGGAGGGAGGAGGAGGAAGGGGCTGTCGTTCTGCTAATCAGAGCGGAC AACCCTGACCTGCCTCTGTTCTGCTGTTGACCTCTGATGTGACCACAAGGTTGGGGACTA ACAGTTTGGAATGGGAGCTAGAATTCAAGGATGAAAAGTCTTCCTGTCCACTGCCTCAAA GGCCTTGCTTCCATTCCTAAAAATGCAGGAGGCCCAGCCAGATGGCCGCTCTGACCATGG AAGCCCATCCAGCCCATTTTACGAATGGGGAACCCTAAAACCTTAAGAAGGGACCTGGTT CTAGGCCAAACTCACTGGCCAAGTCGAAATAAGGAACGGGACTTTTTT |
| Restriction Sites | Please inquire |
| ACCN | NM_033238 |
| Insert Size | 4500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_033238.2, NP_150241.2 |
| RefSeq Size | 5600 bp |
| RefSeq ORF | 2649 bp |
| Locus ID | 5371 |
| UniProt ID | P29590 |
| Domains | zf-B_box, RING |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Acute myeloid leukemia, Pathways in cancer, Ubiquitin mediated proteolysis |
| Gene Summary | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longest transcript, and encodes the longest isoform (1, also known as TRIM19alpha). |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215705 | PML (Myc-DDK-tagged)-Human promyelocytic leukemia (PML), transcript variant 1 |
CNY 8,840.00 |
|
| RC215705L3 | Lenti-ORF clone of PML (Myc-DDK-tagged)-Human promyelocytic leukemia (PML), transcript variant 1 |
CNY 10,740.00 |
|
| RC215705L4 | Lenti-ORF clone of PML (mGFP-tagged)-Human promyelocytic leukemia (PML), transcript variant 1 |
CNY 10,740.00 |
|
| RG215705 | PML (tGFP-tagged) - Human promyelocytic leukemia (PML), transcript variant 1 |
CNY 8,704.00 |
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