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l Afadin (AFDN) (NM_001040000) Human Untagged Clone
CAT＃: SC311059
MLLT4 (untagged)-Human myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), translocated to, 4 (MLLT4), transcript variant 2
CNY 16,952.00
货期*
现货
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AF6; l-afadin; MLL-AF6; MLLT4 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_001040000 edited
ATGTCGGCGGGCGGCCGTGACGAGGAGCGGCGGAAGCTGGCCGACATCATCCACCACTGG AACGCCAACCGGCTGGACCTGTTCGAGATCAGCCAGCCGACCGAGGATTTGGAGTTCCAT GGAGTGATGAGATTTTATTTTCAAGATAAAGCTGCTGGAAACTTTGCAACAAAATGTATT CGGGTCTCTAGTACTGCCACCACTCAAGATGTAATCGAAACGCTCGCGGAGAAATTTCGA CCTGATATGCGAATGCTGTCCTCTCCCAAGTATTCACTCTATGAAGTGCATGTCAGCGGA GAAGAAAGAAGATTGGATATAGATGAGAAACCTCTAGTTGTACAACTGAATTGGAACAAA GATGATCGGGAAGGCAGATTTGTTCTTAAGAATGAGAATGACGCCATTCCTCCTAAGAAG GCTCAAAGTAATGGACCTGAAAAGCAGGAAAAAGAAGGGGTTATCCAGAACTTCAAGAGA ACTCTCTCAAAGAAAGAAAAGAAGGAAAAAAAGAAGAGAGAAAAAGAGGCATTGCGACAG GCATCTGATAAAGATGATAGACCTTTCCAAGGGGAGGATGTTGAAAATTCTCGACTGGCT GCTGAGGTTTACAAAGACATGCCGGAAACCAGCTTTACTCGAACCATTTCTAATCCTGAG GTGGTTATGAAACGACGGAGGCAGCAAAAATTGGAAAAGAGAATGCAGGAATTTCGGAGC TCAGATGGGCGGCCTGATTCAGGTGGAACATTGAGAATTTATGCAGATAGTTTAAAACCA AATATTCCCTACAAGACAATCCTGCTGTCTACTACAGATCCTGCAGACTTTGCTGTGGCT GAAGCTTTAGAGAAGTATGGTCTGGAAAAAGAAAACCCTAAGGATTACTGCATCGCCCGG GTTATGCTTCCTCCTGGAGCCCAGCATTCTGATGAAAAGGGTGCTAAAGAAATTATTCTT GATGATGATGAGTGTCCTTTACAAATCTTCAGGGAATGGCCAAGTGACAAAGGGATTTTA GTCTTTCAGTTGAAGAGGAGGCCACCAGACCACATCCCAAAGAAAACCAAGAAACACTTG GAAGGCAAGACACCCAAGGGAAAGGAGAGAGCTGACGGGTCTGGCTATGGCTCCACCCTT CCTCCGGAGAAGCTGCCCTATTTAGTAGAGTTAAGCCCAGGGAGAAGGAATCACTTTGCC TACTACAACTATCACACTTACGAAGATGGTTCTGACTCTAGAGATAAGCCAAAGCTTTAC CGCCTTCAGTTAAGTGTTACTGAAGTTGGGACAGAAAAGTTGGATGACAACTCTATCCAG TTGTTTGGCCCAGGAATTCAGCCCCATCACTGTGACCTTACCAACATGGATGGAGTGGTC ACTGTGACGCCCAGAAGTATGGACGCAGAAACCTACGTGGAAGGCCAGCGCATCTCAG:A AACCACCATGCTGCAGAGTGGCATGAAAGTGCAGTTTGGGGCGTCCCATGTATTTAAGTT TGTGGACCCCAGTCAGGATCATGCTCTTGCAAAAAGATCTGTGGATGGAGGCCTGATGGT TAAGGGCCCAAGACATAAACCTGGAATTGTTCAGGAGACAACTTTTGATTTGGGAGGAGA TATTCATAGTGGGACAGCATTACCGACAAGCAAGAGCACCACTAGGCTGGACAGCGACAG AGTGTCGTCTGCCTCTAGCACAGCCGAGCGGGGAATGGTGAAGCCGATGATCAGAGTAGA ACAGCAGCCAGATTATCGCAGGCAAGAAAGCAGAACACAGGATGCTTCTGGGCCTGAGCT GATACTACCTGCAAGCATTGAATTCAGGGAAAGTTCTGAAGATTCATTTTTGTCTGCCAT TATAAATTATACTAATAGCTCTACAGTCCACTTTAAGTTGTCCCCTACATATGTATTATA TATGGCATGCCGGTATGTATTGTCCAACCAGTACAGACCTGACATCAGCCCTACAGAGCG CACACATAAAGTCATTGCAGTCGTCAACAAGATGGTGAGCATGATGGAGGGTGTCATCCA GAAACAGAAGAATATTGCAGGGGCACTTGCCTTCTGGATGGCAAATGCATCTGAACTTCT CAACTTCATTAAGCAAGACCGAGACCTTAGTCGGATCACACTGGATGCTCAAGATGTTTT AGCACATTTGGTTCAAATGGCATTTAAATACTTGGTTCACTGTCTTCAATCAGAACTTAA TAATTACATGCCAGCCTTTCTAGATGACCCTGAAGAGAACAGTCTGCAACGACCAAAAAT AGATGATGTGCTGCACACGCTCACAGGAGCCATGTCCTTGCTACGACGCTGCAGAGTCAA TGCCGCCCTGACCATCCAGCTCTTCTCTCAGCTCTTCCACTTCATCAATATGTGGCTGTT CAATAGATTGGTGACCGACCCAGATTCGGGGCTGTGCTCCCATTACTGGGGTGCGATTAT CCGTCAGCAGTTGGGCCATATTGAAGCCTGGGCTGAGAAGCAGGGGCTGGAACTGGCTGC GGACTGTCATCTGAGCAGGATCGTGCAGGCAACGACTTTGCTTACCATGGATAAGTATGC ACCTGATGACATTCCAAATATAAACAGCACCTGCTTTAAGTTAAATTCATTACAACTTCA AGCCTTATTACAGAACTATCACTGTGCACCTGATGAGCCTTTTATCCCAACGGATCTTAT AGAAAATGTAGTGACTGTGGCTGAAAACACTGCCGATGAGCTGGCCCGCAGTGATGGAAG GGAAGTGCAGTTGGAGGAGGATCCTGATCTGCAGCTGCCGTTTCTTTTGCCAGAAGATGG TTATTCTTGTGATGTTGTCAGAAACATTCCAAATGGTTTACAAGAATTTTTAGACCCTCT GTGCCAGAGAGGATTTTGCAGGTTAATTCCTCACACACGTTCACCAGGTACTTGGACAAT ATATTTTGAAGGTGCAGATTATGAAAGTCACCTTCTGCGTGAGAACACAGAGCTGGCTCA GCCTCTGAGGAAAGAACCTGAAATAATCACTGTGACCCTAAAAAAGCAGAATGGAATGGG CCTTAGCATTGTTGCAGCAAAGGGTGCTGGTCAAGATAAACTAGGAATCTATGTGAAGTC GGTTGTGAAAGGAGGTGCTGCAGATGTGGATGGACGTCTAGCTGCAGGTGATCAGCTCCT CAGTGTGGATGGACGAAGTCTGGTTGGACTCTCTCAGGAAAGGGCGGCAGAACTCATGAC AAGAACAAGCTCTGTGGTGACACTGGAAGTAGCAAAGCAGGGTGCCATCTACCACGGTCT GGCCACCCTTCTCAATCAGCCATCCCCCATGATGCAGAGAATTTCAGATCGTCGTGGCTC AGGTAAACCCCGACCAAAGAGTGAAGGCTTTGAGCTCTATAATAATTCAACTCAAAATGG GTCTCCTGAGAGTCCTCAGCTGCCTTGGGCAGAATATAGTGAACCAAAGAAATTGCCTGG TGATGACAGACTGATGAAAAATAGAGCTGATCACCGTTCCAGCCCCAACGTAGCAAATCA GCCTCCTAGTCCTGGAGGGAAAAGTGCATATGCCTCTGGAACAACAGCGAAGATAACATC TGTCTCTACTGGAAACCTCTGCACTGAGGAGCAGACGCCTCCGCCTAGACCTGAAGCCTA CCCCATCCCCACTCAGACGTACACCAGAGAGTATTTTACCTTCCCAGCTTCCAAATCCCA GGATCGGATGGCTCCTCCTCAGAACCAGTGGCCAAATTATGAGGAAAAGCCACATATGCA CACAGATAGTAATCATTCCAGTATTGCAATTCAGCGTGTTACACGTTCCCAAGAAGAACT TCGAGAAGATAAAGCTTACCAACTTGAGCGGCATCGAATAGAGGCAGCTATGGACCGAAA GTCTGATAGTGATATGTGGATAAATCAGAGCTCCTCACTGGACTCCAGTACCTCTAGCCA GGAGCATCTGAACCATTCCTCTAAGTCGGTCACCCCTGCTTCCACACTGACCAAAAGTGG CCCTGGCCGTTGGAAAACACCAGCAGCCATACCGGCCACCCCTGTGGCCGTCTCCCAGCC AATCCGAACAGACCTGCCTCCGCCACCCCCGCCACCTCCAGTCCACTATGCCGGTGATTT CGATGGAATGTCCATGGATTTGCCTCTCCCACCACCCCCTTCCGCCAACCAGATAGGGCT GCCGTCTGCGCAGGTGGCTGCTGCTGAACGGAGAAAGAGAGAAGAACATCAGCGTTGGTA TGAGAAGGAGAAGGCCCGCCTGGAGGAGGAGCGGGAGAGGAAGCGGAGAGAGCAGGAGAG GAAGTTGGGCCAGATGCGCACTCAGTCCTTAAACCCTGCTCCGTTTTCTCCCCTGACTGC ACAGCAGATGAAGCCCGAAAAGCCTTCCACACTCCAGCGGCCACAGGAAACAGTCATTCG GGAGCTGCAGCCTCAGCAGCAGCCCCGCACGATCGAGCGCAGAGACTTGCAGTACATTAC AGTCAGCAAAGAGGAGCTTTCCTCGGGGGACAGTCTGTCCCCCGACCCGTGGAAGCGGGA CGCCAAGGAGAAGCTGGAGAAGCAGCAGCAGATGCACATCGTGGACATGCTGAGCAAGGA GATCCAGGAGCTCCAGAGCAAACCGGACCGCAGCGCCGAGGAGAGCGACCGGCTGCGCAA GCTCATGCTGGAGTGGCAGTTCCAGAAGAGACTCCAGGAGTCGAAGCAGAAGGACGAAGA TGACGAGGAGGAGGAGGACGATGATGTGGACACCATGCTGATCATGCAGCGCCTGGAGGC TGAACGAAGAGCGAGGGACGAGGAGCGGAGGCGGCAGCAGCAGTTAGAAGAGATGCGCAA GCGGGAAGCGGAAGACCGAGCGAGGCAAGAGGAAGAGCGCCGGCGGCAGGAGGAGGAGCG AACAAAACGAGACGCTGAAGAAAAGGTTATGGTCCTTTAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001040000 |
| Insert Size | 7800 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001040000.1, NP_001035089.1 |
| RefSeq Size | 7551 bp |
| RefSeq ORF | 4956 bp |
| Locus ID | 4301 |
| UniProt ID | P55196 |
| Protein Families | Druggable Genome |
| Protein Pathways | Adherens junction, Leukocyte transendothelial migration, Tight junction |
| Gene Summary | This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011] Transcript Variant: This variant (2) has several differences compared to variant 4. The resulting isoform (2) is longer at the N-terminus but has a shorter and distinct C-terminus compared to isoform 4. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217774 | MLLT4 (Myc-DDK-tagged)-Human myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), translocated to, 4 (MLLT4), transcript variant 2 |
CNY 16,944.00 |
|
| RC217774L3 | Lenti-ORF clone of MLLT4 (Myc-DDK-tagged)-Human myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 (MLLT4), transcript variant 2 |
CNY 13,970.00 |
|
| RC217774L4 | Lenti-ORF clone of MLLT4 (mGFP-tagged)-Human myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 (MLLT4), transcript variant 2 |
CNY 13,970.00 |
|
| RG217774 | MLLT4 (tGFP-tagged) - Human myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 (MLLT4), transcript variant 2 |
CNY 18,544.00 |
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