PANK2 (NM_153638) Human Untagged Clone

CAT#: SC310376

PANK2 (untagged)-Human pantothenate kinase 2 (PANK2), nuclear gene encoding mitochondrial protein, transcript variant 1



  "NM_153638" in other vectors (7)

CNY 4,256.00

CNY 9,220.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
Anti-PANK2 mouse monoclonal antibody, clone OTI3H9 (formerly 3H9)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms C20orf48; HARP; HSS; NBIA1; PKAN
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_153638 edited
GGGTGGATGAGGAGGCTCGGGCCCTTCCACCCACGCGTCCATTGGGCGGCGCCGCCATCA
CTCTCTTCTGGGCTACACCGCCTTCTCTTCCTCCGCGGAACCCGGATCCCCTCCTCCACC
ACCCTCTCCCCGCCCCGTCACGATAGCCTCTCATTGGACGGAGGCACGGTCAATCCTCCT
CGAGTTAGGGAGCCGACTGGACGCGAGGCCTTTGGGCCGTCCCCAGCCTCGTCGGATTGG
CTTCCTGCGCGTTGGCGCAACGGAAGAGGCGGCCGGCCGAGGGCGCGCCTCTGCTCTGGC
TGGACTGCCGCGGAGGAGGCGAGAAGGAATCCGACGCTGGGGGGCTTGCTCGGGCGGCAG
CGACTGCTGCTGCGGATGGGAGGGGGCCGGCTCGGCGCGCCCATGGAGCGCCACGGCAGG
GCTTCCGCCACCTCCGTCTCGTCGGCTGGGGAGCAGGCGGCCGGGGACCCCGAAGGGCGG
CGGCAGGAGCCACTGCGGCGCCGGGCGAGCAGCGCGTCGGTGCCCGCGGTCGGGGCCTCG
GCTGAGGGCACGAGGCGGGATCGACTGGGCTCTTACAGCGGCCCCACCTCGGTCTCCCGC
CAGCGCGTCGAAAGCCTGAGGAAAAAGCGGCCGCTTTTTCCATGGTTTGGACTGGATATC
GGTGGAACTCTGGTCAAGCTGGTATATTTTGAACCCAAAGACATCACTGCTGAAGAAGAA
GAGGAAGAAGTGGAAAGTCTTAAAAGCATTCGGAAGTACCTGACCTCCAATGTGGCTTAT
GGGTCTACAGGCATTCGGGACGTGCACCTCGAGCTGAAGGACCTGACTCTGTGTGGACGC
AAAGGCAATCTGCACTTTATACGCTTTCCCACTCATGACATGCCTGCTTTTATTCAAATG
GGCAGAGATAAAAACTTCTCGAGTCTCCACACTGTCTTTTGTGCCACTGGAGGTGGAGCG
TACAAATTTGAGCAGGATTTTCTCACAATAGGTGATCTTCAGCTTTGCAAACTGGATGAA
CTAGATTGCTTGATCAAAGGAATTTTATACATTGACTCAGTCGGATTCAATGGACGGTCA
CAGTGCTATTACTTTGAAAACCCTGCTGATTCTGAAAAGTGTCAGAAGTTACCATTTGAT
TTGAAAAATCCGTATCCTCTGCTTCTGGTGAACATTGGCTCAGGGGTTAGCATCTTAGCA
GTATATTCCAAAGATAATTACAAACGGGTCACAGGTACTAGTCTTGGAGGAGGAACTTTT
TTTGGTCTCTGCTGTCTTCTTACTGGCTGTACCACTTTTGAAGAAGCTCTTGAAATGGCA
TCTCGTGGAGATAGCACCAAAGTGGATAAACTAGTACGAGATATTTATGGAGGGGACTAT
GAGAGGTTTGGACTGCCAGGCTGGGCTGTGGCTTCAAGCTTTGGAAACATGATGAGCAAG
GAGAAGCGAGAGGCTGTCAGTAAAGAGGACCTGGCCAGAGCGACTTTGATCACCATCACC
AACAACATTGGCTCAATAGCAAGAATGTGTGCCCTTAATGAAAACATTAACCAGGTGGTA
TTTGTTGGAAATTTCTTGAGAATTAATACGATCGCCATGCGGCTTTTGGCATATGCTTTG
GATTATTGGTCCAAGGGGCAGTTGAAAGCACTTTTTTCGGAACACGAGGGTTATTTTGGA
GCTGTTGGAGCACTCCTTGAGCTGTTGAAGATCCCGTGATCATTACCTGGGGAGGGGTTC
CTGAAACCTTCCACAATGGGATCTGTGGACTTTCATTTTTTTAAGAGACTTACTCAATTT
CATGACTGTACTACCTGAAACAAAGTGAGAAAGGACAGGTGTATTTTTCTAAGTCATCAA
GATAAATCCTTAAGAATTCAGTCTAAATTAGCAACCAGGAAGGAAAAATATATTAAAAAC
AACAAAAAAGTGGCACATGTCCAGGCAGTGTGAGGATTTGCTGTATATAAGTTGCCTGCT
TTGTATTTTTGAAATCTCTGCATCACTCATTGGAAGTGCTTCTGAAGAGAGCTGCTCTGT
GTTCAGTTGACTGGTTTTGTGTCCTGTTTGAACTTGCTGAATGTAAGGCAGGCTACTATG
CGTTATAATCTAATCACAATTTGTCAATATGGTCTTGGCAATCATCTGTGCATTACTCTG
GTTTGCATTAAGCCTGTGTGTGAACTTACTGTAAAACATGTTTT
>OriGene 5' read for NM_153638 unedited
GGTTTCATTTGTATACCACTCATATAGGGCGGCCGCGATTCATGAGAGGCTCGGGCCCTT
CCACCCACGCGTCCATTGGGCGGCGCCGCCATCACTCTCTTCTGGGCTACACCGCCTTCT
CTTCCTCCGCGGAACCCGGATCCCCTCCTCCACCACCCTCTCCCCGCCCCGTCACGATAG
CCTCTCATTGGACGGAGGCACGGTCAATCCTCCTCGAGTTAGGGAGCCGACTGGACGCGA
GGCCTTTGGGCCGTCCCCAGCCTCGTCGGATTGGCTTCCTGCGCGTTGGCGCAACGGAAG
AGGCGGCCGGCCGAGGGCGCGCCTCTGCTCTGGCTGGACTGCCGCGGAGGAGGCGAGAAG
GAATCCGACGCTGGGGGGCTTGCTCGGGCGGCAGCGACTGCTGCTGCGGATGGGAGGGGG
CCGGCTCGGCGCGCCCATGGAGCGCCACGGCAGGGCTTCCGCCACCTCCGTCTCGTCGGC
TGGGGAGCAGGCGGCCGGGGACCCCGAAGGGCGGCGGCAGGAGCCACTGCGGCGCCGGGC
GAGCAGCGCGTCGGTGCCCGCGGTCGGGGCCTCGGCTTGAGGCACGAGGCGGGATCGACT
GGGCTCTTACAGCGGCCCCCACCTCGGTCTCCCGCCCGCGCGTCCAAAGCCTGAAGGAAA
AGCGGCCCGCTTTTTCCAGGGTTTGGCCTGGATATCCGTGGAACCTCTGGCAAAGCTGGT
ATATTTTGGACCCCAAAGACTTCCCTGCTTGAAAAAAACAAGGAAGAAATGGAAAGTCTT
AAAAGCCTTTCGGAATTCCTTGCCCCCCAATGTGGGCTAATTGGGCCTACAGGCATTCGG
GGACACGCCACCCCTGAGCTGAAAGGACCTGACTCTTGGTGGGCCCCAAAGCGCATCT
Restriction Sites Please inquire     
ACCN NM_153638
Insert Size 2200 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_153638.2, NP_705902.2
RefSeq Size 2280 bp
RefSeq ORF 1713 bp
Locus ID 80025
UniProt ID Q9BZ23
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Pantothenate and CoA biosynthesis
Gene Summary This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (1) encodes the longest and mitochondrially localized isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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