CDC2L1 (CDK11B) (NM_033488) Human Untagged Clone

CAT#: SC310140

CDK11B (untagged)-Human cyclin-dependent kinase 11B (CDK11B), transcript variant 4



  "NM_033488" in other vectors (4)

CNY 14,160.00


货期*
5周

规格
    • 10 ug

Product images

经常一起买 (4)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00


CD2 biotinylated mouse monoclonal detection antibody, validated for ELISA and Luminex assays
    • 50 ug

CNY 2,700.00
CNY 3,790.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms CDC2L1; CDK11; CDK11-p46; CDK11-p58; CDK11-p110; CLK-1; p58; p58CDC2L1; p58CLK-1; PK58
Vector pCMV6 series
Sequence Data
>NCBI ORF sequence for NM_033488, the custom clone sequence may differ by one or more nucleotides
ATGTCGCAGTCTGATGACCGGGATTCCAAGCGGGATTCCCTTGAGGAGGGGGAGCTGAGA
GATCACCGCATGGAGATCACAATAAGGAACTCCCCGTATAGAAGAGAAGACTCTATGGAA
GACAGAGGAGAAGAAGATGATTCTTTGGCCATCAAACCACCCCAGCAAATGTCTCGGAAA
GAAAAAGTTCATCACAGAAAAGATGAAAAGAGAAAAGAGAAAAAGCATGCTAGAGTGAAA
GAAAAAGAAAGAGAGCACGAACGTCGGAAACGACATCGAGAAGAACAGGATAAAGCTCGC
CGGGAATGGGAAAGACAGAAGAGAAGGGAAATGGCAAGGGAGCATTCCAGGAGAGAAAGG
GACCGCTTGGAGCAGTTAGAAAGGAAGCGGGAGCGGGAGCGCAAGATGCGGGAGCAGCAG
AAGGAGCAGCGGGAGCAGAAGGAGCGCGAGCGGCGGGCGGAGGAGCGGCGCAAGGAGCGG
GAGGCCCGCAGGGAAGTGTCTGCACATCACCGAACGATGAGAGAGGACTACAGCGACAAA
GTGAAAGCCAGCCACTGGAGTCGCAGCCCGCCTCGGCCGCCGCGGGAGCGGTTCGAGTTG
GGAGACGGCCGGAAGCCAGTAAAAGAAGAGAAAATGGAAGAAAGGGACCTGCTGTCCGAC
TTACAGGACATCAGCGACAGCGAGAGGAAGACCAGCTCGGCCGAGTCCTCGTCAGCAGAA
TCAGGCTCAGGTTCTGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGAGGAGGAAGGGAGC
ACCAGTGAAGAATCAGAGGAGGAGGAGGAGGAAGAGGAAGAGGAGGAGGAGGAGACCGGC
AGCAACTCTGAGGAGGCATCAGAGCAGTCTGCCGAAGAAGTAAGTGAGGAAGAAATGAGT
GAAGATGAAGAACGAGAAAATGAAAACCACCTCTTGGTTGTTCCAGAGTCACGGTTCGAC
CGAGATTCCGGGGAGAGTGAAGAAGCAGAGGAAGAAGTGGGTGAGGGAACGCCGCAGAGC
AGCGCCCTGACAGAGGGCGACTATGTGCCCGACTCCCCTGCCCTGTCGCCCATCGAGCTC
AAGCAGGAGCTGCCCAAGTACCTGCCGGCCCTGCAGGGCTGCCGGAGCGTCGAGGAGTTC
CAGTGCCTGAACAGGATCGAGGAGGGCACCTATGGAGTGGTCTACAGAGCAAAAGACAAG
AAAACAGATGAAATTGTGGCTCTAAAGCGGCTGAAGATGGAGAAGGAGAAGGAGGGCTTC
CCGATCACGTCGCTGAGGGAGATCAACACCATCCTCAAGGCCCAGCATCCCAACATCGTC
ACCGTTAGAGAGATTGTGGTGGGCAGCAACATGGACAAGATCTACATCGTGATGAACTAT
GTGGAGCACGACCTCAAGAGCCTGATGGAGACCATGAAACAGCCCTTCCTGCCAGGGGAG
GTGAAGACCCTGATGATCCAGCTGCTGCGTGGGGTGAAACACCTGCACGACAACTGGATC
CTGCACCGTGACCTCAAGACGTCCAACCTGCTGCTGAGCCACGCCGGCATCCTCAAGGTG
GGTGACTTCGGGCTGGCGCGGGAGTACGGATCCCCTCTGAAGGCCTACACCCCGGTCGTG
GTGACCCTGTGGTACCGCGCCCCAGAGCTGCTGCTTGGTGCCAAGGAATACTCCACGGCC
GTGGACATGTGGTCAGTGGGTTGCATCTTCGGGGAGCTGCTGACTCAGAAGCCTCTGTTC
CCCGGGAAGTCAGAAATCGATCAGATCAACAAGGTGTTCAAGGATCTGGGGACCCCTAGT
GAGAAAATCTGGCCCGGCTACAGCGAGCTCCCAGCAGTCAAGAAGATGACCTTCAGCGAG
CACCCCTACAACAACCTCCGCAAGCGCTTCGGGGCTCTGCTCTCAGACCAGGGCTTCGAC
CTCATGAACAAGTTCCTGACCTACTTCCCCGGGAGGAGGATCAGCGCTGAGGACGGCCTC
AAGCATGAGTATTTCCGCGAGACCCCCCTCCCCATCGACCCCTCCATGTTCCCCACGTGG
CCCGCCAAGAGCGAGCAGCAGCGTGTGAAGCGGGGCACCAGCCCGAGGCCCCCTGAGGGA
GGCCTGGGCTACAGCCAGCTGGGTGACGACGACCTGAAGGAGACGGGCTTCCACCTTACC
ACCACGAACCAGGGGGCCTCTGCCGCGGGCCCCGGCTTCAGCCTCAAGTTCTGA
Restriction Sites Please inquire     
ACCN NM_033488
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_033488.1, NP_277023.1
RefSeq Size 2500 bp
RefSeq ORF 2214 bp
Locus ID 984
Domains pkinase
Protein Families Druggable Genome, Transcription Factors
Gene Summary This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Transcript Variant: This variant (4) contains an additional 5' internal fragment and lacks two separated internal coding regions when compared to variant 1. The additional fragment leads to a translation frame shift. The resulting protein has a unique first 3 aa and a 37 aa truncation at the N-terminus, and lacks two separated internal fragments, as compared to isoform 1.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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