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DPP8 (NM_197960) Human Untagged Clone
CAT＃: SC310056
DPP8 (untagged)-Human dipeptidyl-peptidase 8 (DPP8), transcript variant 3
CNY 9,872.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DP8; DPRP-1; DPRP1; MST097; MSTP097; MSTP135; MSTP141 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_197960 edited
ATGTGGAAGAGATCTGAGCAGATGAAAATAAAATCAGGAAAATGCAACATGGCAGCAGCA ATGGAAACAGAACAGCTGGGTGTTGAGATATTTGAAACTGCGGACTGTGAGGAGAATATT GAATCACAGGATCGGCCTAAATTGGAGCCTTTTTATGTTGAGCGGTATTCCTGGAGTCAG CTTAAAAAGCTGCTTGCCGATACCAGAAAATATCATGGCTACATGATGGCTAAGGCACCA CATGATTTCATGTTTGTGAAGAGGAATGATCCAGATGGACCTCATTCAGACAGAATCTAT TACCTTGCCATGTCTGGTGAGAACAGAGAAAATACACTGTTTTATTCTGAAATTCCCAAA ACTATCAATAGAGCAGCAGTCTTAATGCTCTCTTGGAAGCCTCTTTTGGATCTTTTTCAG GCAACACTGGACTATGGAATGTATTCTCGAGAAGAAGAACTATTAAGAGAAAGAAAACGC ATTGGAACAGTCGGAATTGCTTCTTACGATTATCACCAAGGAAGTGGAACATTTCTGTTT CAAGCCGGTAGTGGAATTTATCACGTAAAAGATGGAGGGCCACAAGGATTTACGCAACAA CCTTTAAGGCCCAATCTAGTGGAAACTAGTTGTCCCAACATACGGATGGATCCAAAATTA TGCCCTGCTGATCCAGACTGGATTGCTTTTATACATAGCAACGATATTTGGATATCTAAC ATCGTAACCAGAGAAGAAAGGAGACTCACTTATGTGCACAATGAGCTAGCCAACATGGAA GAAGATGCCAGATCAGCTGGAGTCGCTACCTTTGTTCTCCAAGAAGAATTTGATAGATAT TCTGGCTATTGGTGGTGTCCAAAAGCTGAAACAACTCCCAGTGGTGGTAAAATTCTTAGA ATTCTATATGAAGAAAATGATGAATCTGAGGTGGAAATTATTCATGTTACATCCCCTATG TTGGAAACAAGGAGGGCAGATTCATTCCGTTATCCTAAAACAGGTACAGCAAATCCTAAA GTCACTTTTAAGATGTCAGAAATAATGATTGATGCTGAAGGAAGGATCATAGATGTCATA GATAAGGAACTAATTCAACCTTTTGAGATTCTATTTGAAGGAGTTGAATATATTGCCAGA GCTGGATGGACTCCTGAGGGAAAATATGCTTGGTCCATCCTACTAGATCGCTCCCAGACT CGCCTACAGATAGTGTTGATCTCACCTGAATTATTTATCCCAGTAGAAGATGATGTTATG GAAAGGCAGAGACTCATTGAGTCAGTGCCTGATTCTGTGACGCCACTAATTATCTATGAA GAAACAACAGACATCTGGATAAATATCCATGACATCTTTCATGTTTTTCCCCAAAGTCAC GAAGAGGAAATTGAGTTTATTTTTGCCTCTGAATGCAAAACAGGTTTCCGTCATTTATAC AAAATTACATCTATTTTAAAGGAAAGCAAATATAAACGATCCAGTGGTGGGCTGCCTGCT CCAAGTGATTTCAAGTGTCCTATCAAAGAGGAGATAGCAATTACCAGTGGTGAATGGGAA GTTCTTGGCCGGCATGGATCTAATATCCAAGTTGATGAAGTCAGAAGGCTGGTATATTTT GAAGGCACCAAAGACTCCCCTTTAGAGCATCACCTGTACGTAGTCAGTTACGTAAATCCT GGAGAGGTGACAAGGCTGACTGACCGTGGCTACTCACATTCTTGCTGCATCAGTCAGCAC TGTGACTTCTTTATAAGTAAGTATAGTAACCAGAAGAATCCACACTGTGTGTCCCTTTAC AAGCTATCAAGTCCTGAAGATGACCCAACTTGCAAAACAAAGGAATTTTGGGCCACCATT TTGGATTCAGCAGGTCCTCTTCCTGACTATACTCCTCCAGAAATTTTCTCTTTTGAAAGT ACTACTGGATTTACATTGTATGGGATGCTCTACAAGCCTCATGATCTACAGCCTGGAAAG AAATATCCTACTGTGCTGTTCATATATGGTGGTCCTCAGGTGCAGTTGGTGAATAATCGG TTTAAAGGAGTCAAGTATTTCCGCTTGAATACCCTAGCCTCTCTAGGTTATGTGGTTGTA GTGATAGACAACAGGGGATCCTGTCACCGAGGGCTTAAATTTGAAGGCGCCTTTAAATAT AAAATGGGTCAAATAGAAATTGACGATCAGGTGGAAGGACTCCAATATCTAGCTTCTCGA TATGATTTCATTGACTTAGATCGTGTGGGCATCCACGGCTGGTCCTATGGAGGATACCTC TCCCTGATGGCATTAATGCAGAGGTCAGATATCTTCAGGGTTGCTATTGCTGGGGCCCCA GTCACTCTGTGGATCTTCTATGATACAGGATACACGGAACGTTATATGGGTCACCCTGAC CAGAATGAACAGGGCTATTACTTAGGATCTGTGGCCATGCAAGCAGAAAAGTTCCCCTCT GAACCAAATCGTTTACTGCTCTTACATGGTTTCCTGGATGAGAATGTCCATTTTGCACAT ACCAGTATATTACTGAGTTTTTTAGTGAGGGCTGGAAAGCCATATGATTTACAGATCTAT CCTCAGGAGAGACACAGCATAAGAGTTCCTGAATCGGGAGAACATTATGAACTGCATCTT TTGCACTACCTTCAAGAAAACCTTGGATCACGTATTGCTGCTCTAAAAGTGATATAATTT TGACCTGTGTAGAACTCTCTGGTATACACTGGCTATTTAACCAAATGAGGAGGTTTAATC AACAGAAAACACAGAATTGATCATCACATTTTGATACCTGCCATGTAACATCTACTCCTG AAAATAAATGTGGTGCCATGCAGGGGTCTACGGTTTGTGGTAGTAATCTAATACCTTAAC CCCACATGCTCAAAATCAAATGATACATATTCCTGAGAGACCCAGCAATACCATAAGAAT TACTAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_197960 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_197960.1, NP_932064.1 |
| RefSeq Size | 3055 bp |
| RefSeq ORF | 2697 bp |
| Locus ID | 54878 |
| UniProt ID | Q6V1X1 |
| Protein Families | Druggable Genome, Protease, Transmembrane |
| Gene Summary | This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region which results in the use of an alternate start codon, compared to variant 1. The encoded isoform (3) is longer and has a distinct N-terminus compared to isoform 1. Both variants 3 and 6 encode the same isoform (3). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Selective Inhibition of Fibroblast Activation Protein Protease Based on Dipeptide Substrate Specificity
,Conrad Yap Edosada, Clifford Quan, Christian Wiesmann, Thuy Tran, Dan Sutherlin, Mark Reynolds, J. Michael Elliott, Helga Raab, Wayne Fairbrother, and Beni B. Wolf,
J. Biol. Chem., Vol. 281, Issue 11, 7437-7444, March 17, 2006
[DPP8]
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