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GRIK3 (NM_000831) Human Untagged Clone
CAT＃: SC310048
GRIK3 (untagged)-Human glutamate receptor, ionotropic, kainate 3 (GRIK3)
CNY 17,670.00
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EAA5; GLR7; GluK3; GLUR7; GluR7a |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_000831 |
| Insert Size | 2760 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000831.3 |
| RefSeq Size | 9225 bp |
| RefSeq ORF | 2760 bp |
| Locus ID | 2899 |
| UniProt ID | Q13003 |
| Domains | lig_chan, ANF_receptor |
| Protein Families | Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| MW | 104 kDa |
| Gene Summary | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223571 | GRIK3 (Myc-DDK-tagged)-Human glutamate receptor, ionotropic, kainate 3 (GRIK3) |
CNY 10,096.00 |
|
| RC223571L1 | Lenti ORF clone of Human glutamate receptor, ionotropic, kainate 3 (GRIK3), Myc-DDK-tagged |
CNY 12,496.00 |
|
| RC223571L2 | Lenti ORF clone of Human glutamate receptor, ionotropic, kainate 3 (GRIK3), mGFP tagged |
CNY 12,496.00 |
|
| RC223571L3 | Lenti ORF clone of Human glutamate receptor, ionotropic, kainate 3 (GRIK3), Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC223571L4 | Lenti ORF clone of Human glutamate receptor, ionotropic, kainate 3 (GRIK3), mGFP tagged |
CNY 9,030.00 |
|
| RG223571 | GRIK3 (tGFP-tagged) - Human glutamate receptor, ionotropic, kainate 3 (GRIK3) |
CNY 11,696.00 |
