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LLGL2 (NM_004524) Human Untagged Clone
CAT＃: SC310006
LLGL2 (untagged)-Human lethal giant larvae homolog 2 (Drosophila) (LLGL2), transcript variant 1
CNY 19,570.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HGL; Hugl-2; LGL2 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_004524, the custom clone sequence may differ by one or more nucleotides
ATGAGGCGGTTCCTGAGGCCAGGGCATGACCCTGTGCGGGAGAGGCTCAAGCGGGACCTG TTCCAGTTTAACAAGACGGTGGAGCATGGCTTCCCGCACCAGCCCAGCGCCCTCGGCTAC AGCCCGTCCCTGCGCATCCTGGCCATCGGCACCCGTTCTGGAGCCATCAAGCTCTACGGA GCCCCAGGCGTGGAGTTCATGGGGCTGCACCAGGAGAACAACGCTGTGACGCAGATCCAC CTCCTGCCCGGCCAGTGCCAGCTGGTCACCCTGCTGGATGACAACAGCCTGCACCTTTGG AGCCTGAAGGTCAAGGGCGGGGCATCGGAGCTGCAGGAGGATGAGAGCTTCACACTGCGT GGACCCCCAGGGGCTGCCCCCAGTGCCACACAGATCACCGTGGTCCTGCCACATTCCTCC TGCGAGCTGCTCTACCTGGGCACCGAGAGTGGCAACGTGTTTGTGGTGCAGCTGCCAGCT TTTCGTGCGCTGGAGGACCGGACCATCAGCTCGGACGCGGTGCTGCAGCGGTTGCCAGAG GAGGCCCGCCACCGGCGTGTGTTCGAGATGGTGGAGGCACTGCAGGAGCACCCTCGAGAC CCCAACCAGATCCTGATCGGCTACAGCCGAGGCCTCGTTGTCATCTGGGACCTACAGGGC AGCCGCGTGCTCTACCACTTCCTCAGCAGCCAGCAACTGGAGAACATCTGGTGGCAGCGG GACGGCCGCCTGCTCGTCAGCTGTCACTCTGACGGCAGCTACTGCCAGTGGCCCGTGTCC AGCGAAGCCCAGCAACCAGAGCCCCTCCGCAGCCTCGTGCCTTACGGTCCCTTTCCTTGC AAAGCGATTACCAGAATCCTCTGGCTGACCACTAGGCAGGGGTTGCCCTTCACCATCTTC CAGGGTGGCATGCCACGGGCCAGCTACGGGGACCGCCACTGCATCTCAGTGATCCACGAT GGCCAGCAGACGGCCTTCGACTTCACCTCCCGTGTCATCGGCTTCACTGTCCTCACAGAG GCAGACCCTGCAGCCACCTTTGACGACCCCTATGCCCTGGTGGTGCTGGCTGAGGAGGAG CTGGTGGTGATTGACCTGCAGACAGCAGGCTGGCCACCGGTCCAGCTGCCCTACCTGGCT TCTCTGCACTGTTCCGCCATCACCTGCTCTCACCACGTCTCCAACATCCCGCTGAAGCTG TGGGAGCGGATCATTGCCGCCGGCAGCCGGCAGAACGCACACTTCTCCACCATGGAGTGG CCAATTGATGGTGGCACCAGCCTGACCCCAGCCCCACCCCAGAGGGACCTGCTGCTCACA GGGCACGAGGACGGCACGGTGCGGTTCTGGGATGCCTCGGGTGTCTGCCTGCGGCTGCTC TACAAACTCAGCACTGTGCGCGTGTTCCTCACCGACACGGACCCCAACGAGAACTTCAGT GCCCAGGGCGAGGACGAGTGGCCCCCACTCCGCAAGGTGGGCTCCTTTGACCCCTACAGT GATGACCCCCGGCTGGGCATCCAGAAGATCTTCCTCTGCAAGTACAGCGGCTACCTGGCT GTGGCAGGCACGGCAGGGCAGGTGCTGGTACTGGAACTGAATGACGAGGCAGCGGAGCAG GCTGTGGAGCAGGTGGAGGCCGACCTGCTGCAGGACCAAGAGGGCTACCGCTGGAAGGGG CACGAGCGCCTGGCAGCCCGCTCAGGGCCCGTGCGCTTTGAGCCTGGCTTTCAGCCCTTC GTGTTGGTGCAGTGTCAGCCCCCGGCTGTGGTCACCTCCTTGGCCCTGCACTCTGAGTGG CGGCTCGTGGCCTTCGGCACCAGCCATGGCTTTGGCCTCTTTGACCACCAGCAGCGGCGG CAGGTCTTTGTTAAGTGCACACTGCACCCCAGTGACCAGCTGGCCTTGGAGGGCCCACTC TCCCGCGTCAAGTCCCTCAAGAAGTCCTTGCGTCAGTCATTCCGCCGGATGCGTCGGAGC CGGGTGTCCAGCCGGAAGCGGCACCCGGCTGGCCCCCCAGGAGAGGCACAGGAGGGGAGT GCCAAGGCTGAGCGGCCAGGCCTCCAGAACATGGAGCTGGCGCCTGTGCAGCGCAAGATC GAGGCTCGCTCGGCAGAGGACTCCTTCACAGGCTTCGTCCGGACCCTGTACTTTGCTGAC ACCTACCTGAAGGACAGCTCCCGGCACTGCCCCTCGCTGTGGGCTGGCACCAATGGGGGC ACCATCTATGCCTTCTCCCTGCGTGTGCCTCCCGCCGAGCGGAGAATGGATGAGCCTGTG CGGGCAGAGCAGGCCAAGGAGATCCAGCTGATGCACCGGGCGCCGGTGGTGGGCATCCTG GTGCTCGACGGACACAGCGTACCCCTTCCCGAGCCCCTCGAAGTGGCCCATGATCTGTCG AAGAGCCCTGACATGCAGGGAAGCCACCAGCTGCTCGTCGTATCAGAGGAGCAGTTCAAG GTGTTCACGCTGCCCAAGGTGAGTGCCAAGCTGAAGTTGAAGCTGACGGCCCTGGAGGGC TCAAGAGTGCGGCGGGTCAGCGTGGCCCACTTCGGCAGTCGTCGAGCCGAGGACTACGGG GAGCACCACCTGGCAGTCCTTACCAACCTGGGCGACATCCAGGTGGTCTCGCTGCCCCTG CTCAAGCCCCAGGTGCGCTACAGCTGCATCCGCCGGGAGGACGTCAGTGGCATCGCCTCC TGCGTCTTCACCAAATATGGCCAAGGCTTCTACCTGATCTCACCCTCGGAGTTTGAGCGC TTCTCTCTCTCCACCAAGTGGCTGGTGGAGCCCCGGTGTCTGGTGGATTCAGCAGAAACC AAGAACCACCGCCCTGGTAACGGTGCGGGCCCCAAGAAGGCCCCGAGCCGAGCCAGGAAC TCAGGGACTCAGAGTGATGGCGAGGAGAAGCAGCCCGGCCTGGTGATGGAGCGCGCTCTG CTCAGTGATGAGAGAGCGGCAACTGGCGTTCACATCGAGCCGCCGTGGGGTGCAGCCTCA GCAATGGCGGAGCAGAGTGAGTGGCTGAGCGTCCAGGCTGCGCGATGA |
| Restriction Sites | Please inquire |
| ACCN | NM_004524 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004524.2, NP_004515.2 |
| RefSeq Size | 3547 bp |
| RefSeq ORF | 3048 bp |
| Locus ID | 3993 |
| UniProt ID | Q6P1M3 |
| Domains | WD40 |
| Protein Families | Druggable Genome |
| Protein Pathways | Tight junction |
| Gene Summary | The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) lacks an alternate exon in the coding region compared to variant 3, that causes a frameshift. The resulting isoform (a) is shorter and has a distinct C-terminus compared to isoform c. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212604 | LLGL2 (Myc-DDK-tagged)-Human lethal giant larvae homolog 2 (Drosophila) (LLGL2), transcript variant 1 |
CNY 10,600.00 |
|
| RC212604L3 | Lenti-ORF clone of LLGL2 (Myc-DDK-tagged)-Human lethal giant larvae homolog 2 (Drosophila) (LLGL2), transcript variant 1 |
CNY 12,070.00 |
|
| RC212604L4 | Lenti-ORF clone of LLGL2 (mGFP-tagged)-Human lethal giant larvae homolog 2 (Drosophila) (LLGL2), transcript variant 1 |
CNY 12,070.00 |
|
| RG212604 | LLGL2 (tGFP-tagged) - Human lethal giant larvae homolog 2 (Drosophila) (LLGL2), transcript variant 1 |
CNY 11,210.00 |
