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FBXL11 (KDM2A) (NM_012308) Human Untagged Clone
CAT＃: SC309965
KDM2A (untagged)-Human lysine (K)-specific demethylase 2A (KDM2A), transcript variant 1
CNY 8,096.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CXXC8; FBL7; FBL11; FBXL11; JHDM1A; LILINA |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_012308 edited
CCTGCGGCCGGGGCCGGCCCGGGGCTCGGGCCCGGGCTGCTGACCGCTGGCCTGGGGGAG GCGGGGGCGCCCCGGGCTCGGCGCCGAGGGGTCGCGCTCCTCTCTCCTGACGCCTCCGAC TCCCGGTCTCCAAAGCCAGAAGAGAAGGTTTGATTCAGCAACTGTTTGCTCCCTTTTCCT GGTCGCTCTGACCCTCTCTGGATACTGGGTTGATCCACGGAAAAACCGAAGACGACGTTT GGGATTTAATTATTCCTCTCAGCTTTGGAATCTTTTACTTCTCACTTGGACAAGAACTCA AGAGCAGAATCTCCGTGTTGCAATCTGGTTCCTAAGGAGGAAGAGGAAGGCAGCCCTGGA GTGGTTTCTTTACAGTAATTTCAACAGAAGAGTGAGAGATGGAACCCGAAGAAGAAAGGA TTCGTTACAGCCAGAGATTGCGTGGTACCATGCGACGACGCTATGAAGATGATGGCATTT CAGATGATGAAATTGAAGGAAAAAGAACTTTTGACTTGGAAGAGAAACTGCACACCAACA AATATAATGCCAATTTTGTTACTTTTATGGAAGGAAAAGATTTTAATGTAGAGTATATTC AGCGGGGTGGCTTGAGAGATCCTCTGATTTTCAAGAATTCTGATGGACTCGGAATAAAAA TGCCGGATCCAGACTTCACTGTGAATGATGTCAAAATGTGTGTGGGGAGTCGTCGCATGG TGGATGTCATGGACGTGAACACACAGAAAGGCATTGAAATGACCATGGCTCAGTGGACAC GCTACTATGAGACCCCAGAGGAGGAGCGAGAGAAACTCTATAATGTCATCAGCCTCGAGT TTAGCCACACCAGGCTGGAGAATATGGTGCAGAGGCCCTCCACGGTGGATTTCATTGACT GGGTAGACAACATGTGGCCAAGGCACTTGAAGGAAAGCCAGACTGAATCAACAAATGCCA TCTTGGAGATGCAGTACCCTAAAGTGCAGAAGTACTGTCTAATGAGTGTTCGAGGCTGCT ATACTGACTTCCATGTGGACTTTGGTGGTACCTCTGTTTGGTATCACATCCATCAAGGGG GAAAGGTCTTCTGGCTCATCCCCCCTACAGCCCACAACCTGGAGCTGTACGAGAATTGGC TGCTGTCAGGGAAACAGGGAGACATCTTTCTGGGTGACCGGGTATCAGATTGTCAGCGCA TTGAGCTCAAGCAGGGCTATACCTTCGTCATTCCCTCAGGCTGGATTCATGCTGTGTATA CTCCTACAGACACATTAGTGTTTGGGGGCAATTTTTTGCATAGCTTCAACATCCCTATGC AGTTAAAAATATACAACATTGAAGATCGGACACGGGTTCCAAATAAGTTTCGCTATCCAT TCTACTATGAGATGTGTTGGTATGTGTTGGAGCGCTATGTGTACTGCATAACCAACCGTT CCCACCTAACCAAGGAATTTCAGAAAGAGTCCCTCAGCATGGATTTGGAGTTAAATGGGT TGGAGTCTGGGAATGGGGATGAGGAAGCAGTGGATCGAGAACCCCGACGCTTGAGCAGCA GGCGTTCTGTCCTCACTAGCCCTGTAGCGAATGGAGTCAACCTGGATTATGATGGACTGG GCAAAACCTGCCGAAGTCTTCCAAGTCTGAAGAAAACTTTGGCTGGGGACTCATCTTCTG ACTGTAGCCGGGGCTCCCACAATGGACAAGTGTGGGATCCCCAGTGTGCTCCCCGAAAGG ACAGGCAAGTGCATCTGACCCATTTTGAGCTTGAAGGCCTTCGCTGCCTTGTAGATAAGT TGGAGTCTCTGCCACTGCACAAGAAATGTGTCCCCACAGGGATAGAAGATGAAGATGCTC TCATTGCTGATGTAAAGATTTTGCTGGAGGAGCTTGCCAACAGCGATCCCAAGTTAGCCC TCACTGGAGTTCCTATAGTACAGTGGCCAAAAAGGGATAAGCTTAAATTCCCCACTCGGC CAAAGGTGCGGGTTCCTACCATCCCCATTACGAAGCCTCACACTATGAAACCAGCTCCAC GGTTAACACCTGTGAGGCCAGCTGCTGCCTCCCCGATTGTGTCAGGAGCCAGACGGAGAC GAGTGCGATGTCGAAAATGCAAAGCCTGTGTGCAAGGAGAGTGTGGTGTTTGCCACTACT GCAGAGACATGAAGAAGTTTGGGGGGCCTGGACGCATGAAGCAGTCCTGTGTCCTCCGAC AGTGCTTGGCACCCAGACTGCCTCACTCAGTCACATGTTCCCTCTGTGGAGAGGTGGATC AGAATGAAGAGACACAAGACTTTGAGAAGAAACTCATGGAATGCTGTATCTGCAATGAGA TTGTTCATCCTGGCTGCCTCCAGATGGACGGAGAGGGGTTGCTTAACGAAGAATTGCCAA ATTGCTGGGAATGTCCAAAGTGCTACCAGGAGGACAGCTCGGAGAAAGCCCAGAAGCGGA AAATGGAAGAGAGTGACGAAGAAGCTGTGCAAGCCAAAGTCCTGCGGCCCCTGCGGAGCT GCGATGAGCCTCTCACGCCCCCGCCTCATTCACCCACTTCCATGCTGCAGCTCATCCATG ACCCGGTTTCCCCCCGGGGTATGGTGACTCGGTCATCCCCTGGGGCTGGCCCCAGCGACC ACCACAGTGCCAGCCGCGATGAGCGCTTCAAACGGCGGCAGTTGCTGCGGCTGCAGGCCA CAGAGCGCACCATGGTACGGGAAAAGGAGAACAATCCCAGCGGCAAAAAGGAGCTGTCTG AAGTTGAGAAAGCCAAGATCCGGGGATCGTACCTCACTGTCACGCTACAGAGGCCCACCA AAGAGCTCCACGGGACATCCATTGTGCCCAAGCTGCAGGCCATCACGGCCTCCTCTGCCA ACCTTCGCCATTCCCCCCGTGTGCTAGTGCAGCACTGCCCAGCCCGAACCCCCCAGCGTG GGGATGAGGAGGGGCTGGGGGGAGAGGAGGAGGAAGAGGAGGAGGAGGAGGAGGAAGATG ACAGTGCAGAGGAGGGGGGTGCAGCCAGGCTGAATGGCCGGGGCAGTTGGGCTCAGGATG GAGACGAAAGCTGGATGCAGCGGGAGGTCTGGATGTCTGTCTTCCGCTACCTCAGCCGCA GAGAACTTTGTGAATGTATGCGAGTGTGCAAGACGTGGTATAAATGGTGCTGCGACAAGA GACTTTGGACAAAAATTGACTTGAGTAGGTGTAAGGCCATTGTGCCCCAGGCCCTCAGTG GCATCATCAAGAGGCAGCCAGTCAGCCTTGACCTCAGTTGGACCAACATCTCTAAAAAGC AACTGACATGGCTCGTCAATAGGCTGCCAGGACTGAAAGACCTCCTCCTAGCAGGCTGCT CCTGGTCTGCAGTCTCTGCCCTCAGCACCTCCAGCTGCCCCCTTCTCAGGACCCTTGATC TTCGGTGGGCAGTAGGAATCAAGGACCCTCAAATTCGGGACTTGCTTACTCCACCGGCTG ATAAACCAGGTCAGGACAATCGCAGCAAGCTCCGGAACATGACCGACTTCCGGCTGGCAG GCCTTGACATCACAGATGCCACGCTTCGCCTCATAATTCGCCACATGCCCCTCCTGTCTC GACTCGACCTCAGTCACTGCAGCCACCTTACAGATCAGTCCTCCAATCTACTCACTGCTG TCGGGTCTTCCACTCGCTACTCTCTCACAGAGCTCAATATGGCAGGTTGCAATAAATTGA CAGACCAGACCCTGATCTACCTACGGCGCATTGCCAACGTCACCTTGATCGACCTTCGAG GATGCAAGCAGATCACTCGAAAAGCCTGCGAGCACTTCATCTCAGACTTGTCCATCAACA GCCTCTACTGCCTGTCTGACGAGAAGCTGATACAGAAGATCAGCTAAGACACACCCAGCC CAGATTCAACAGGAAACCGATCTTCCCCTGACTCCCCACCGAGGAGAGCCTCTCCTCGAC CCTGCACGGGCTCTGAGGCCAGCGTCACACTCCCTCTCTGCTCTCCTGTCCCTTGAGCCC TTCCTCTACAGGTGGGGCAGAGAGGGTGGTGGACACCAGGCTTATCTGCCTGCTCCTCTC CCTCCTAAGGAAAAGGGAGTAGCAGATTGATCTGAGGGGAAAGCACAGGCTGTGCTGTCG AGGCGCCTGCTCGCTTACTCGCCTGCCAGGAGGCCGGGCTCTCAGTTTGGGGTGTTTGTG CAACCTTCATCTGCACTGGGCCCTGTGCCCCTCCTCCCCATCCATGGTCCCCAGCAGTGC CTGGTTCTGAGCAAACTCCCA >Reverse primer walk for NM_012308 unedited
ATTTNCAATGGCCTTTNCTGTGTGNNTTCACGTCCATGGNACATCCACCATGGGCGACGA CTCCCCACACACATTTTGACATCATTCACAGTGAAGTCTGGATCCGGCATTTTTATTCCG AGTCCATCAGAATTCTTGAAAATCAGAGGATCTCTCAAGCCACCCCGCTGAATATACTCT ACATTAAAATCTTTTCCTTCCATAAAAGTAACAAAATTGGCATTATATTTGTTGGTGTGC AGTTTCTCTTCCAAGTCAAAAGTTCTTTTTCCTTCAATTTCATCATCTGAAATGCCATCA TCTTCATAGCGTCGTCGCATGGTACCACGCAATCTCTGGCTGTAACGAATCCTTTCTTCT TCGGGTTCCATCTCTCACTCTTCTGTTGAAATTACTGTAAAGAAACCACTCCAGGGCTGC CTTCCTCTTCCTCCTTAGGAACCAGATTGCAACACGGAGATTCTGCTCTTGAGTTCTTGT CCAAGTGAGAAGTAAAAGATTCCAAAGCTGAGAGGAATAATTAAATCCCAAACGTCGTCT TCGGTTTTTCCGTGGATCAACCCAGTATCCAGAGAGGGTCAGAGCGACCAGGANAAGGGA GCAAACAGTTGCTGAATCAAACCTTCTCTTCTGGCTTTGGAGACCGGGAGTCGGAGGCGT CAGGAGAGAGGAGCGCGACCCCTCGGCGCCGAGCCCCGGGGCGCCCCCGCCTCCCCCAGG CCAGCGGTCAGCAGCCCGGGCCCGAGCCCCGGGCCGGCCCCGGCCGCAGGGAGCGCCCTC CTTGCCGTGCCCTNCGCCAGCAAGGGCTGGCCTCGTGCCCGATTTCGCGGCCCCCTATAG TGAGTCCTATTACCAAA >OriGene 3' read for NM_012308 unedited
NNCCATCGGNNGATGGCACTTNCCAGGNCCAGNAAAGCACTGGGGNAGGGTCACAGGGAT GCCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTT TTTTTTTTTTTTTTTAAACTGCAAAAAGCTATGTGCTGCCCTAGAGAGAGGATCTTTGGA CAGGCCGTTCAATGCAAAGTAAAAGGGGGCAGCTGATGGGGCTCAACAAAGGGCGGTGGA GCGGGAGACACCATGCTCCCCTCCCTCCCTCCCTCCACACACACGCGCAGAATACACTCA GCCACACACACAGAGGCACGTGCACACCCCCTTCCATGGCTGCAGGCAGAGGGCTGGTGA CTGGCTTCTAAGCAGGACCCCCTGACTGCCCTGAAAGTTCAGTGAGCCACTGGGGCTAGA CACAGGCCTGGGCTCAGGGGGCTCCGCTAAACCAGAGGCCTGGAGGAGCCTGGCTGGGAG GCAGGTTGGGGCTTGGCCCAGTCCTCTGCCGCCTCCAGCTTGGGGGAGATAGGCTGCTCC CTCTGAAGACGTGCATCCTGGGAAAGCCTTCTCAGGCAGATGAAAACACAGGGAAAAGGC AGTCAGTGGGAGGCAAAAAAAAAAGGGGAACAAGGAAAAGGGGGCCGTCCCAAAAACCAC TTGGGGACCAACAAAAAGGGGTGGCCCCTGGGGTAAACATTCCCGCCCCCCGAAGAGCTT AACCCCCAAAAAGGCAAAAAGGACCTCTTAAAACCAACCAATAAATCCGGTAAACCGGGG GGGGAAACCCTATTTTGGGAACAACCCCAATGCTGGGGAAAACCCACCCCAAGGGAAAGA AAAAAGAGGGAACACCCTTTAAAGGCCGGG |
| Restriction Sites | Please inquire |
| ACCN | NM_012308 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_012308.1, NP_036440.1 |
| RefSeq Size | 6210 bp |
| RefSeq ORF | 3489 bp |
| Locus ID | 22992 |
| UniProt ID | Q9Y2K7 |
| Domains | F-box, PHD, zf-CXXC, JmjC, LRR_CC |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223440 | KDM2A (Myc-DDK-tagged)-Human lysine (K)-specific demethylase 2A (KDM2A), transcript variant 1 |
CNY 8,088.00 |
|
| RC223440L1 | Lenti ORF clone of Human lysine (K)-specific demethylase 2A (KDM2A), transcript variant 1, Myc-DDK-tagged |
CNY 10,488.00 |
|
| RC223440L2 | Lenti ORF clone of Human lysine (K)-specific demethylase 2A (KDM2A), transcript variant 1, mGFP tagged |
CNY 13,490.00 |
|
| RC223440L3 | Lenti ORF clone of Human lysine (K)-specific demethylase 2A (KDM2A), transcript variant 1, Myc-DDK-tagged |
CNY 10,488.00 |
|
| RC223440L4 | Lenti ORF clone of Human lysine (K)-specific demethylase 2A (KDM2A), transcript variant 1, mGFP tagged |
CNY 10,488.00 |
|
| RG223440 | KDM2A (tGFP-tagged) - Human lysine (K)-specific demethylase 2A (KDM2A), transcript variant 1 |
CNY 9,688.00 |
